MetaADEDB 2.0 @ LMMD
Isradipine
(HMJIYCCIJYRONP-UHFFFAOYSA-N)
Structure
SMILES
COC(=O)C1=C(C)NC(=C(C1c1cccc2c1non2)C(=O)OC(C)C)C
Type(s)
Approved; Investigational
ATC code(s)
C08CA03
Molecular Formula:
C19H21N3O5
Molecular Weight:
371.387
Log P:
2.9110
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
1
TPSA:
103.55
CAS Number(s):
75695-93-1
Synonym(s)
1.
Isradipine
2.
Dynacirc
3.
Isradipine, (+-)-Isomer
4.
Isradipine, (R)-Isomer
5.
Isradipine, (S)-Isomer
6.
Lomir
7.
PN 200-110
8.
PN 205-033
9.
PN 205-034
10.
PN-200-110
11.
PN-205-033
12.
PN-205-034
13.
PN 205 033
14.
PN 205 034
15.
PN 205033
16.
PN 205034
17.
PN205033
18.
PN205034
External Link(s)
MeSHD017275
PubChem Compound3784
BindingDB50436176
ChEBI6073
CHEMBLCHEMBL315436
CHEMBL3211306
CHEMBL1648
DrugBankDB00270
DrugCentral1511
IUPHAR/BPS Guide to PHARMACOLOGY4488
KEGGdr:D00349
Therapeutic Target DatabaseD0HC8Q
D0Z7KE
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 6US FAERS
2HeadacheFAERS: 31451544
1827026
8466725		CTD
SIDER
US FAERS
3Joint swellingFAERS: 2US FAERS
4Medication residueFAERS: 2OFFSIDES
US FAERS
5OverdoseFAERS: 2US FAERS
6Product quality issueFAERS: 2US FAERS
7Unevaluable eventFAERS: 2US FAERS
8Adverse eventFAERS: 1US FAERS
9AgitationFAERS: 1US FAERS
10ArthralgiaFAERS: 1SIDER
US FAERS
11DizzinessFAERS: 11451544
1827026
8466725		CTD
OFFSIDES
SIDER
US FAERS
12Drug administration errorFAERS: 1US FAERS
13Drug dispensing errorFAERS: 1US FAERS
14Feeling abnormalFAERS: 1SIDER
US FAERS
15HypersensitivityFAERS: 1US FAERS
16Joint injuryFAERS: 1US FAERS
17Labile blood pressureFAERS: 1US FAERS
18MyalgiaFAERS: 1US FAERS
19Myocardial InfarctionFAERS: 18769587CTD
SIDER
US FAERS
20Neck PainFAERS: 1US FAERS
21NervousnessFAERS: 1SIDER
US FAERS
22Physical assaultFAERS: 1US FAERS
23PruritusFAERS: 1SIDER
US FAERS
24Suicide attemptFAERS: 1US FAERS
25Therapeutic response unexpectedFAERS: 1OFFSIDES
US FAERS
26TinnitusFAERS: 1US FAERS
27Transcription medication errorFAERS: 1US FAERS
28Urinary tract infectionFAERS: 1US FAERS
29AbasiaOFFSIDES
30Abdominal InfectionOFFSIDES
31Abdominal discomfortOFFSIDES
SIDER
32Abnormal visionOFFSIDES
33Acid refluxOFFSIDES
34AcidosisOFFSIDES
35ActinomycosisOFFSIDES
36Acute Coronary SyndromeSIDER
37Acute respiratory failureOFFSIDES
38Acute sinusitisOFFSIDES
39Adnexa uteri cystOFFSIDES
40AgoraphobiaOFFSIDES
41AgraphiaOFFSIDES
42AlveolitisOFFSIDES
43AlveoloplastyOFFSIDES
44AmnesiaOFFSIDES
45Amphetamine-Related Disorders15850499CTD
46Anaphylactic shockSIDER
47AneurysmOFFSIDES
48Angina Pectoris

View details

1703598
7918132
8769587
11002857
 		CTD
SIDER
49Angioedema19077729CTD
SIDER
50AnisocoriaOFFSIDES
51AnorexiaOFFSIDES
52AnosmiaOFFSIDES
53AnxietyOFFSIDES
SIDER
54Aortic valve sclerosisOFFSIDES
55Application site irritationOFFSIDES
56Application site pruritusOFFSIDES
57Arteriovenous fistula occlusionOFFSIDES
58Arteriovenous fistula thrombosisOFFSIDES
59ArthroscopyOFFSIDES
60AspergillosisOFFSIDES
61AstheniaOFFSIDES
SIDER
62AsthmaOFFSIDES
63Ataxia12196060CTD
64Atherosclerosis

View details

1376828
1695298
1720479
2150640
7670645
7789292
8205295
8769587
8934382
8973777
 		CTD
65Atrial FibrillationSIDER
66AutomatismOFFSIDES
67Back PainSIDER
68Back disorderOFFSIDES
69Bacteria tissue specimen identifiedOFFSIDES
70Bacterial test positiveOFFSIDES
71Basal cell carcinomaOFFSIDES
72BiopsyOFFSIDES
73Blood alkaline phosphatase increasedOFFSIDES
74Blood cholesterolOFFSIDES
75Blood creatinine increasedOFFSIDES
76Blood electrolytes abnormalOFFSIDES
77Blood glucose decreasedOFFSIDES
78Blood magnesium increasedOFFSIDES
79Blood pH decreasedOFFSIDES
80Blood pressure inadequately controlledOFFSIDES
81Blood thyroid stimulating hormone increasedOFFSIDES
82Bone painOFFSIDES
83Bone swellingOFFSIDES
84Bone trimmingOFFSIDES
85Bradycardia12066967CTD
SIDER
86Brain Ischemia11481148CTD
87BronchitisOFFSIDES
88Burning sensationOFFSIDES
89BursitisOFFSIDES
90Capillary Leak SyndromeOFFSIDES
91Cardiac stress test abnormalOFFSIDES
92Cataract operationOFFSIDES
93CataractOFFSIDES
94Catheter placementOFFSIDES
95Central line infectionOFFSIDES
96Cerebellar infarctionOFFSIDES
97Cerebrovascular accidentSIDER
98Cervical cord compressionOFFSIDES
99Chest PainOFFSIDES
SIDER
100Choking sensationOFFSIDES
101ChoroiditisOFFSIDES
102Chronic left ventricular failureOFFSIDES
103Cocaine-Related Disorders1828708
9738534
12957222		CTD
104Compression fractureOFFSIDES
105Congenital tricuspid valve incompetenceOFFSIDES
106ConstipationSIDER
107CryingOFFSIDES
108Cutaneous sarcoidosisOFFSIDES
109Cytolytic hepatitisOFFSIDES
110Decreased LibidoOFFSIDES
111DehydrationOFFSIDES
112Delayed sleep phaseOFFSIDES
113Dental examinationOFFSIDES
114Denture wearerOFFSIDES
115Depressed moodOFFSIDES
116DermatitisSIDER
117Diabetic FootOFFSIDES
118DiarrheaOFFSIDES
119Diastolic dysfunctionOFFSIDES
120DiscomfortSIDER
121Disease ProgressionOFFSIDES
122Disturbance in sexual arousalSIDER
123DrowsinessSIDER
124Drug effect delayedOFFSIDES
125Drug withdrawal headacheOFFSIDES
126Duodenal ulcer perforationOFFSIDES
127Dysarthria12196060CTD
128DyspepsiaSIDER
129Economic problemOFFSIDES
130Edema1827026CTD
131Ejection Fraction DecreasedOFFSIDES
132Electrocardiogram QT corrected intervalOFFSIDES
133EpistaxisOFFSIDES
134Erectile dysfunctionOFFSIDES
SIDER
135ErythemaOFFSIDES
136ExcoriationOFFSIDES
137Failure to ThriveOFFSIDES
138FatigueOFFSIDES
SIDER
139Fatty LiverOFFSIDES
140FlatulenceOFFSIDES
141Flushing

View details

1451544
1827026
8466725
10777026
 		CTD
SIDER
142Focal glomerulosclerosisOFFSIDES
143GammopathyOFFSIDES
144Gingival HyperplasiaSIDER
145GoutOFFSIDES
146GranulocytosisOFFSIDES
147Heart Diseases23707769CTD
148Heart failure8769587CTD
149HepatitisSIDER
150Hyperosmolar stateOFFSIDES
151HyperparathyroidismOFFSIDES
152HyperpigmentationOFFSIDES
153Hyperplasia15257873CTD
154Hypertensive heart diseaseOFFSIDES
155Hyperviscosity syndromeOFFSIDES
156HyporeflexiaOFFSIDES
157Hypotension8480506CTD
SIDER
158Immunoglobulins abnormalOFFSIDES
159Injection site erythemaOFFSIDES
160Intervertebral disc disorderOFFSIDES
161Intestinal Diseases19077729CTD
162Joint Range of Motion DecreasedOFFSIDES
163Joint sprainOFFSIDES
164Kidney FailureOFFSIDES
165Kidney NeoplasmOFFSIDES
166Left Ventricular HypertrophyOFFSIDES
167Left atrial dilatationOFFSIDES
168LegionellaOFFSIDES
169Lethargy12196060CTD
OFFSIDES
SIDER
170LeukopeniaSIDER
171Long QT SyndromeOFFSIDES
172MalaiseSIDER
173Malignant neoplasm progressionOFFSIDES
174MalnutritionSIDER
175Medical device complicationOFFSIDES
176Metabolic acidosisOFFSIDES
177MetamorphopsiaOFFSIDES
178Monoclonal immunoglobulin presentOFFSIDES
179MonoplegiaOFFSIDES
180Motor retardationOFFSIDES
181Movement Disorders18947822CTD
182Multiple MyelomaOFFSIDES
183Multiple SclerosisOFFSIDES
184Muscle Weakness12196060CTD
OFFSIDES
185Muscle tightnessOFFSIDES
186Musculoskeletal PainOFFSIDES
187Musculoskeletal chest painOFFSIDES
188Musculoskeletal discomfortOFFSIDES
SIDER
189MutismOFFSIDES
190Nail bed infectionOFFSIDES
191NauseaOFFSIDES
SIDER
192Nephrogenic Fibrosing DermopathyOFFSIDES
193NocturiaSIDER
194NumbnessSIDER
195Oral infectionOFFSIDES
196Oropharyngeal discomfortSIDER
197Oropharyngeal painSIDER
198OsteolysisOFFSIDES
199OsteomyelitisOFFSIDES
200OsteoradionecrosisOFFSIDES
201OsteosclerosisOFFSIDES
202PallorOFFSIDES
203PalpitationsSIDER
204ParanoiaOFFSIDES
205PneumoperitoneumOFFSIDES
206PolyhydramniosOFFSIDES
207PolyuriaSIDER
208Poor dental conditionOFFSIDES
209ProstatismOFFSIDES
210Proteinuria9176849CTD
211PsoriasisOFFSIDES
212Pulmonary HypertensionOFFSIDES
213Pulmonary thrombosisOFFSIDES
214Purulent dischargeOFFSIDES
215QRS axis abnormalOFFSIDES
216Renal Artery StenosisOFFSIDES
217Renal cystOFFSIDES
218Renal failure neonatalOFFSIDES
219Renal massOFFSIDES
220Retinal vascular occlusionOFFSIDES
221RhinorrheaOFFSIDES
222ScotomaOFFSIDES
223SerositisOFFSIDES
224ShockSIDER
225Sick Sinus SyndromeOFFSIDES
226Skin IndurationOFFSIDES
227Skin hypertrophyOFFSIDES
228Skin lacerationOFFSIDES
229Skin lesionOFFSIDES
230Skin necrosisOFFSIDES
231Small bowel angioedemaOFFSIDES
232SomnolenceSIDER
233Spinal column stenosisOFFSIDES
234Subcutaneous AbscessOFFSIDES
235Subcutaneous EmphysemaOFFSIDES
236Supraventricular tachycardiaOFFSIDES
237SyncopeSIDER
238Tachycardia

View details

1827026
8466725
10777026
15925741
 		CTD
SIDER
239TensionSIDER
240ThrombocytopeniaSIDER
241TineaOFFSIDES
242Tooth ExtractionOFFSIDES
243Tricuspid valve sclerosisOFFSIDES
244Troponin increasedOFFSIDES
245Urine output increasedSIDER
246UrticariaSIDER
247Vasospasm, Intracranial12202012CTD
248Ventricular FibrillationSIDER
249Ventricular arrhythmiaSIDER
250Violence-related symptomOFFSIDES
251Visual ImpairmentSIDER
252Visual disturbanceSIDER
253VomitingSIDER
254Weight GainOFFSIDES
255Wound dehiscenceOFFSIDES
256Wound infection staphylococcalOFFSIDES
257bone marrow fibrosisOFFSIDES
258nervous system disorderSIDER
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