MetaADEDB 2.0 @ LMMD
Cefepime
(HVFLCNVBZFFHBT-ZKDACBOMSA-N)
Structure
SMILES
CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])C[N+]1(C)CCCC1
Type(s)
Approved; Investigational
ATC code(s)
J01DE01; J01RA06
Molecular Formula:
C19H24N6O5S2
Molecular Weight:
480.561
Log P:
-0.4111
Hydrogen Bond Acceptor:
12
Hydrogen Bond Donor:
2
TPSA:
203.58
CAS Number(s):
88040-23-7
Synonym(s)
1.
Cefepime
2.
Axépim
3.
BMY 28142
4.
BMY-28142
5.
Cefepim
6.
Cefepime Hydrochloride
7.
Maxipime
8.
Quadrocef
9.
BMY28142
External Link(s)
MeSHD000077723
PubChem Compound5479537
BindingDB50292244
50350470
ChEBI478164
CHEMBLCHEMBL186
DrugBankDB01413
DrugCentral535
KEGGcpd:C08111
dr:D02376
Therapeutic Target DatabaseD0A1CB
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1MyoclonusFAERS: 45SIDER
US FAERS
2Status EpilepticusFAERS: 3711498064CTD
OFFSIDES
SIDER
US FAERS
3NeutropeniaFAERS: 30SIDER
US FAERS
4Altered state of consciousnessFAERS: 29OFFSIDES
SIDER
US FAERS
5AphasiaFAERS: 29US FAERS
6Mental status changesFAERS: 25OFFSIDES
US FAERS
7Acute kidney injuryFAERS: 17US FAERS
8PruritusFAERS: 17SIDER
US FAERS
9AgitationFAERS: 15SIDER
US FAERS
10DeliriumFAERS: 1516344542CTD
US FAERS
11UrticariaFAERS: 1511792017CTD
SIDER
US FAERS
12Blood creatinine increasedFAERS: 13OFFSIDES
US FAERS
13LethargyFAERS: 12US FAERS
14ThrombocytopeniaFAERS: 12SIDER
US FAERS
15Blood urea increasedFAERS: 10OFFSIDES
US FAERS
16AstheniaFAERS: 9US FAERS
17Depressed Level of ConsciousnessFAERS: 9SIDER
US FAERS
18SomnolenceFAERS: 9US FAERS
19TremorFAERS: 9US FAERS
20White blood cell count decreasedFAERS: 9US FAERS
21Drug ineffectiveFAERS: 8US FAERS
22OverdoseFAERS: 8US FAERS
23Toxicity to various agentsFAERS: 8US FAERS
24DisorientationFAERS: 7US FAERS
25Electroencephalogram abnormalFAERS: 7US FAERS
26Anaphylactic shockFAERS: 6SIDER
US FAERS
27HypersensitivityFAERS: 6SIDER
US FAERS
28Respiratory FailureFAERS: 6OFFSIDES
US FAERS
29ShockFAERS: 6SIDER
US FAERS
30Therapy cessationFAERS: 6US FAERS
31Abdominal PainFAERS: 5OFFSIDES
SIDER
US FAERS
32AngioedemaFAERS: 5US FAERS
33ErythemaFAERS: 5SIDER
US FAERS
34HeadacheFAERS: 5SIDER
US FAERS
35HypotensionFAERS: 5US FAERS
36Incorrect dose administeredFAERS: 5US FAERS
37LeukopeniaFAERS: 5SIDER
US FAERS
38NauseaFAERS: 5SIDER
US FAERS
39Neutrophil count decreasedFAERS: 5OFFSIDES
US FAERS
40Cardiac ArrestFAERS: 4US FAERS
41General physical health deteriorationFAERS: 4US FAERS
42Pharmaceutical product complaintFAERS: 4US FAERS
43SepsisFAERS: 4SIDER
US FAERS
44Unresponsive to stimuliFAERS: 4OFFSIDES
US FAERS
45nervous system disorderFAERS: 4US FAERS
46Chest PainFAERS: 3US FAERS
47ChillsFAERS: 3SIDER
US FAERS
48ChoreoathetosisFAERS: 3US FAERS
49Clostridium colitisFAERS: 3US FAERS
50DehydrationFAERS: 3OFFSIDES
US FAERS
51Disseminated Intravascular CoagulationFAERS: 3OFFSIDES
US FAERS
52DyslaliaFAERS: 3US FAERS
53Erythema MultiformeFAERS: 3SIDER
US FAERS
54Lip swellingFAERS: 3US FAERS
55Medication ErrorFAERS: 3US FAERS
56MonoplegiaFAERS: 3US FAERS
57NephritisFAERS: 3US FAERS
58PainFAERS: 3SIDER
US FAERS
59PancytopeniaFAERS: 3SIDER
US FAERS
60Posterior reversible encephalopathy syndromeFAERS: 3US FAERS
61PregnancyFAERS: 3US FAERS
62Respiratory arrestFAERS: 3US FAERS
63Stevens-Johnson SyndromeFAERS: 325811541CTD
SIDER
US FAERS
64StuporFAERS: 316344542CTD
SIDER
US FAERS
65Tardive DyskinesiaFAERS: 3US FAERS
66Urinary tract infectionFAERS: 3SIDER
US FAERS
67VomitingFAERS: 3SIDER
US FAERS
68Alanine Aminotransferase IncreasedFAERS: 2OFFSIDES
SIDER
US FAERS
69Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
70Back PainFAERS: 2US FAERS
71Brain DeathFAERS: 2US FAERS
72Burning sensationFAERS: 2US FAERS
73Cerebrovascular accidentFAERS: 2US FAERS
74ChoreaFAERS: 2US FAERS
75ClonusFAERS: 2US FAERS
76Clostridium difficile colitisFAERS: 2OFFSIDES
US FAERS
77ColitisFAERS: 2OFFSIDES
SIDER
US FAERS
78Creatinine renal clearance decreasedFAERS: 2US FAERS
79CrystalluriaFAERS: 2US FAERS
80Drug administration errorFAERS: 2OFFSIDES
US FAERS
81Drug level increasedFAERS: 2US FAERS
82EncephalitisFAERS: 2OFFSIDES
US FAERS
83FatigueFAERS: 2US FAERS
84Febrile NeutropeniaFAERS: 2OFFSIDES
US FAERS
85FlushingFAERS: 2US FAERS
86HyperreflexiaFAERS: 2US FAERS
87Inappropriate schedule of drug administrationFAERS: 2US FAERS
88InfectionFAERS: 2OFFSIDES
SIDER
US FAERS
89Intestinal ObstructionFAERS: 2US FAERS
90Lupus-like syndromeFAERS: 2US FAERS
91MalaiseFAERS: 2US FAERS
92Myocardial InfarctionFAERS: 2US FAERS
93PeritonitisFAERS: 2OFFSIDES
US FAERS
94PneumoniaFAERS: 2SIDER
US FAERS
95PurpuraFAERS: 2US FAERS
96Rash erythematousFAERS: 2US FAERS
97Renal tubular necrosisFAERS: 2OFFSIDES
US FAERS
98SwellingFAERS: 2US FAERS
99Therapy changeFAERS: 2US FAERS
100TuberculosisFAERS: 2US FAERS
101WheezingFAERS: 2US FAERS
102pseudomembranous colitisFAERS: 2SIDER
US FAERS
103AbasiaFAERS: 1US FAERS
104Abdominal discomfortFAERS: 1OFFSIDES
US FAERS
105Accidental overdoseFAERS: 1US FAERS
106Accidental underdoseFAERS: 1US FAERS
107AcidosisFAERS: 1OFFSIDES
US FAERS
108Activities of daily living impairedFAERS: 1US FAERS
109Adverse eventFAERS: 1US FAERS
110ArthralgiaFAERS: 1US FAERS
111AsphyxiaFAERS: 1US FAERS
112AsterixisFAERS: 1US FAERS
113Atrial FibrillationFAERS: 1US FAERS
114Bladder dysfunctionFAERS: 1US FAERS
115Blood creatine increasedFAERS: 1US FAERS
116BradycardiaFAERS: 1US FAERS
117Cardiac stress test abnormalFAERS: 1US FAERS
118CellulitisFAERS: 111528241CTD
US FAERS
119Chest discomfortFAERS: 1US FAERS
120CholecystitisFAERS: 1US FAERS
121CholestasisFAERS: 1SIDER
US FAERS
122ChromaturiaFAERS: 1US FAERS
123Clostridium difficile infectionFAERS: 1US FAERS
124Coma scale abnormalFAERS: 1US FAERS
125Coronary Artery DiseaseFAERS: 1US FAERS
126Cystic FibrosisFAERS: 1US FAERS
127DementiaFAERS: 1US FAERS
128DermatomyositisFAERS: 1US FAERS
129Device leakageFAERS: 1US FAERS
130Device related infectionFAERS: 1OFFSIDES
US FAERS
131DizzinessFAERS: 1SIDER
US FAERS
132Documented hypersensitivity to administered drugFAERS: 1US FAERS
133Drug dose omissionFAERS: 1US FAERS
134Drug monitoring procedure incorrectly performedFAERS: 1US FAERS
135Drug prescribing errorFAERS: 1US FAERS
136Drug resistanceFAERS: 1US FAERS
137Drug toxicityFAERS: 1US FAERS
138DysarthriaFAERS: 1US FAERS
139DysphemiaFAERS: 1US FAERS
140DystoniaFAERS: 121354086CTD
US FAERS
141EczemaFAERS: 1US FAERS
142Emotional distressFAERS: 1OFFSIDES
US FAERS
143Enterococcal sepsisFAERS: 1OFFSIDES
US FAERS
144EosinophiliaFAERS: 1SIDER
US FAERS
145Eosinophilic PneumoniaFAERS: 1US FAERS
146Epigastric discomfortFAERS: 1US FAERS
147EpilepsyFAERS: 1US FAERS
148ExtravasationFAERS: 1SIDER
US FAERS
149Eyelid Function DisorderFAERS: 1US FAERS
150Feeling abnormalFAERS: 1SIDER
US FAERS
151Flank PainFAERS: 1US FAERS
152HemiplegiaFAERS: 1US FAERS
153Histone antibody positiveFAERS: 1US FAERS
154Hypertensive crisisFAERS: 1US FAERS
155HypophagiaFAERS: 1OFFSIDES
US FAERS
156HypoxiaFAERS: 1OFFSIDES
US FAERS
157ImmobileFAERS: 1US FAERS
158Inappropriate affectFAERS: 1US FAERS
159Incorrect route of drug administrationFAERS: 1US FAERS
160Infusion site painFAERS: 1US FAERS
161Injection Site ReactionFAERS: 1US FAERS
162Injection related reactionFAERS: 1US FAERS
163Injection site erythemaFAERS: 1US FAERS
164Injection site inflammationFAERS: 1SIDER
US FAERS
165Injection site painFAERS: 1US FAERS
166Injection site warmthFAERS: 1US FAERS
167Intentional drug misuseFAERS: 1US FAERS
168Live BirthFAERS: 1US FAERS
169Liver AbscessFAERS: 1US FAERS
170Lung infection pseudomonalFAERS: 1US FAERS
171Medical device complicationFAERS: 1US FAERS
172Muscle RigidityFAERS: 1US FAERS
173Muscle necrosisFAERS: 1US FAERS
174MyalgiaFAERS: 1US FAERS
175Neck PainFAERS: 1US FAERS
176NephrolithiasisFAERS: 1OFFSIDES
US FAERS
177NervousnessFAERS: 1US FAERS
178No reaction on previous exposure to drugFAERS: 1US FAERS
179Nonspecific reactionFAERS: 1US FAERS
180Oral painFAERS: 1US FAERS
181OsteomyelitisFAERS: 116545177CTD
OFFSIDES
US FAERS
182PallorFAERS: 1US FAERS
183PalpitationsFAERS: 1US FAERS
184Peripheral swellingFAERS: 1US FAERS
185PerseverationFAERS: 1US FAERS
186PetechiaeFAERS: 1US FAERS
187PhotophobiaFAERS: 1US FAERS
188Product label confusionFAERS: 1US FAERS
189Product label issueFAERS: 1US FAERS
190Product packaging confusionFAERS: 1US FAERS
191Product substitution issueFAERS: 1US FAERS
192Pseudomonas test positiveFAERS: 1US FAERS
193RectoceleFAERS: 1US FAERS
194Renal cystFAERS: 1US FAERS
195Respiratory distressFAERS: 1US FAERS
196RetchingFAERS: 1US FAERS
197SeromaFAERS: 1US FAERS
198Serum SicknessFAERS: 1US FAERS
199Sinus bradycardiaFAERS: 1US FAERS
200Slow speechFAERS: 1US FAERS
201StrabismusFAERS: 1US FAERS
202StridorFAERS: 1US FAERS
203TachycardiaFAERS: 1US FAERS
204ThrombosisFAERS: 1US FAERS
205Urinary RetentionFAERS: 1US FAERS
206VasculitisFAERS: 1US FAERS
207Wrong technique in drug usage processFAERS: 1US FAERS
208jaundiceFAERS: 1US FAERS
209Abdominal InfectionOFFSIDES
SIDER
210Abnormalities, Drug-Induced29596928CTD
211Acquired diaphragmatic eventrationOFFSIDES
212Acute myocardial infarctionOFFSIDES
213Acute respiratory failureOFFSIDES
214AgranulocytosisSIDER
215AgraphiaOFFSIDES
216AlveolitisOFFSIDES
217AnhidrosisOFFSIDES
218AnorexiaOFFSIDES
219Anticonvulsant drug level above therapeuticOFFSIDES
220AnxietyOFFSIDES
221Aortic AneurysmOFFSIDES
222ArteriosclerosisOFFSIDES
223ArthritisOFFSIDES
224ArthropathyOFFSIDES
225AscitesOFFSIDES
226Aspiration PneumoniaOFFSIDES
227AtelectasisOFFSIDES
228Atrial FlutterOFFSIDES
229Atrioventricular BlockOFFSIDES
230Band neutrophil percentage increasedOFFSIDES
231BiopsyOFFSIDES
232Blood alkaline phosphatase increasedOFFSIDES
SIDER
233Blood beta-D-glucan increasedOFFSIDES
234Blood chloride increasedOFFSIDES
235Blood creatine phosphokinase decreasedOFFSIDES
236Blood creatine phosphokinase increasedOFFSIDES
237Blood lactate dehydrogenase increasedOFFSIDES
238Blood pH decreasedOFFSIDES
239Blood phosphorus decreasedOFFSIDES
SIDER
240Blood potassium decreasedOFFSIDES
241Blood potassium increasedSIDER
242Blood sodiumOFFSIDES
243Blurred visionOFFSIDES
244Bone scan abnormalOFFSIDES
245Brain Diseases16344542CTD
246Brain HypoxiaOFFSIDES
247Brain natriuretic peptide increasedOFFSIDES
248BronchitisSIDER
249Bunion operationOFFSIDES
250BunionOFFSIDES
251Ca++ increasedSIDER
252Calcium lowSIDER
253Carotid artery aneurysmOFFSIDES
254Catheter sepsisOFFSIDES
255Central Nervous System InfectionOFFSIDES
256Choking sensationOFFSIDES
257Chronic Obstructive Airway DiseaseOFFSIDES
258Coagulation test abnormalOFFSIDES
259Colon adenomaOFFSIDES
260Compression fractureOFFSIDES
261ConfabulationOFFSIDES
262Confusion21354086CTD
263ConstipationSIDER
264CyanosisOFFSIDES
265Cytomegalovirus hepatitisOFFSIDES
266Cytomegalovirus test positiveOFFSIDES
267DebridementOFFSIDES
268DemyelinationOFFSIDES
269DermatitisSIDER
270Device FailureOFFSIDES
271DiarrheaOFFSIDES
272Diastolic dysfunctionOFFSIDES
273DisabilitySIDER
274DrowsinessOFFSIDES
275Drug Eruptions11792017CTD
276Dry gangreneOFFSIDES
277DysgeusiaSIDER
278Economic problemOFFSIDES
279Ejection Fraction DecreasedOFFSIDES
280Embryo Loss29596928CTD
281Enterobacter pneumoniaOFFSIDES
282Enterococcal infectionOFFSIDES
283EnterocolitisOFFSIDES
284Epidural Abscess11778010CTD
285EpistaxisOFFSIDES
286Erosive gastritisOFFSIDES
287ExcitabilitySIDER
288ExophthalmosOFFSIDES
289Failure to ThriveOFFSIDES
290Feeding tube complicationOFFSIDES
291Fever17325906CTD
292GangreneOFFSIDES
293Gastrointestinal PainSIDER
294Gastrointestinal arteriovenous malformationOFFSIDES
295Gastrointestinal hypomotilityOFFSIDES
296GranulocytosisOFFSIDES
297Hallucinations, mixedOFFSIDES
298Heparin-induced thrombocytopeniaOFFSIDES
299Hepatic impairmentSIDER
300HepatitisOFFSIDES
301HypospadiasOFFSIDES
302Iliac artery stenosisOFFSIDES
303InflammationSIDER
304Infusion Site ExtravasationOFFSIDES
305Intentional self-injuryOFFSIDES
306Intermittent ClaudicationOFFSIDES
307Intervertebral Disc DegenerationOFFSIDES
308Intervertebral disc disorderOFFSIDES
309Joint injuryOFFSIDES
310Kidney FailureOFFSIDES
311Left Ventricular HypertrophyOFFSIDES
312Leukopenia neonatalOFFSIDES
313Life expectancy shortenedOFFSIDES
314Local reactionSIDER
315Loose toothOFFSIDES
316Lumbar radiculopathyOFFSIDES
317Lymph nodes scan abnormalOFFSIDES
318Lymphocyte percentage decreasedOFFSIDES
319Lymphoid tissue hyperplasiaOFFSIDES
320Metabolic acidosisOFFSIDES
321MetatarsalgiaOFFSIDES
322MucormycosisOFFSIDES
323Multi-organ disorderOFFSIDES
324Muscle hypertrophyOFFSIDES
325Musculoskeletal chest painOFFSIDES
326ObstructionOFFSIDES
327Oral candidiasisSIDER
328Orbital infectionOFFSIDES
329OsteolysisOFFSIDES
330OsteopeniaOFFSIDES
331OsteoporosisOFFSIDES
332OsteosclerosisOFFSIDES
333Papillary muscle disorderOFFSIDES
334ParophthalmiaOFFSIDES
335Performance status decreasedOFFSIDES
336Pericardial effusion29596928CTD
337PhlebitisSIDER
338Phosphorus lowSIDER
339Phrenic nerve paralysisOFFSIDES
340Pneumocystis jiroveci pneumoniaOFFSIDES
341PneumothoraxOFFSIDES
342Postrenal failureOFFSIDES
343Potassium increasedSIDER
344Productive CoughOFFSIDES
345Pulmonary HypertensionOFFSIDES
346Pulmonary radiation injuryOFFSIDES
347PyelonephritisSIDER
348RalesOFFSIDES
349Reticulocyte count increasedOFFSIDES
350RhonchiOFFSIDES
351Seizures12779103CTD
352Septic ShockOFFSIDES
353SepticemiaSIDER
354Serratia sepsisOFFSIDES
355Sinus headacheOFFSIDES
356Sinus operationOFFSIDES
357SinusitisOFFSIDES
358Skin lesionOFFSIDES
359Skin necrosisOFFSIDES
360Spinal fusion surgeryOFFSIDES
361Sputum culture positiveOFFSIDES
362Staphylococcal Infections8150772CTD
363Stasis dermatitisOFFSIDES
364Stem cell transplantOFFSIDES
365Stenotrophomonas infectionOFFSIDES
366Subcutaneous EmphysemaOFFSIDES
367Sudden deathOFFSIDES
368Synovial CystOFFSIDES
369TinnitusOFFSIDES
370Tooth ExtractionOFFSIDES
371Tooth LossOFFSIDES
372Toxic Epidermal NecrolysisSIDER
373TracheitisOFFSIDES
374Transaminases abnormalOFFSIDES
375Troponin increasedOFFSIDES
376Urine sodium abnormalOFFSIDES
377Vascular insufficiencyOFFSIDES
378Vasodilation procedureSIDER
379VasodilationSIDER
380Venoocclusive diseaseOFFSIDES
381Venous InsufficiencyOFFSIDES
382Venous occlusionOFFSIDES
383Ventricular FibrillationOFFSIDES
384VertebroplastyOFFSIDES
385Vitamin K DeficiencyOFFSIDES
386Vulvovaginal mycotic infectionSIDER
387colonoscopyOFFSIDES
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