MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Metolazone

(AQCHWTWZEMGIFD-UHFFFAOYSA-N)

Structure

SMILES: CC1Nc2cc(Cl)c(cc2C(=O)N1c1ccccc1C)S(=O)(=O)N
Type(s): Approved
ATC code(s): C03BA08; C03EA12; G01AE10
Molecular Formula:: C16H16ClN3O3S
Molecular Weight:: 365.835
Log P:: 4.6982
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 2
TPSA:: 100.88
CAS Number(s):: 17560-51-9; 56436-31-8; 56436-32-9

Synonym(s)

Metolazone

Diulo

Microx

Mykrox

SR-720-22

Zaroxolyn

SR 720 22

SR72022

External Link(s)

MeSH	D008788
PubChem Compound	4170
BindingDB	25899
ChEBI	64354
CHEMBL	CHEMBL878
DrugBank	DB00524
DrugCentral	1783
IUPHAR/BPS Guide to PHARMACOLOGY	4838
KEGG	dr:D00431
Therapeutic Target Database	D01WLC

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Dehydration	FAERS: 11		OFFSIDES US FAERS
2	Asthenia	FAERS: 9 Canada Vigilance: 1		Canada Vigilance OFFSIDES SIDER US FAERS
3	Dizziness	FAERS: 9		OFFSIDES SIDER US FAERS
4	Hypotension	FAERS: 9		US FAERS
5	Blood potassium decreased	FAERS: 8		OFFSIDES US FAERS
6	Nausea	FAERS: 7	11572578	CTD OFFSIDES SIDER US FAERS
7	Syncope	FAERS: 6		SIDER US FAERS
8	Drug ineffective	FAERS: 5		US FAERS
9	Pharmaceutical product complaint	FAERS: 5		OFFSIDES US FAERS
10	Polyuria	FAERS: 4		OFFSIDES US FAERS
11	Acute kidney injury	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
12	Headache	FAERS: 3		SIDER US FAERS
13	Pancreatitis	FAERS: 3	1928234	CTD SIDER US FAERS
14	Pruritus	FAERS: 3		SIDER US FAERS
15	Vomiting	FAERS: 3		SIDER US FAERS
16	Back Pain	FAERS: 2		SIDER US FAERS
17	Cardiac Arrest	FAERS: 2		US FAERS
18	Constipation	FAERS: 2		SIDER US FAERS
19	Drug dispensing error	FAERS: 2		US FAERS
20	Ejection Fraction Decreased	FAERS: 2		OFFSIDES US FAERS
21	Fatigue	FAERS: 2		OFFSIDES SIDER US FAERS
22	Feeling abnormal	FAERS: 2		OFFSIDES SIDER US FAERS
23	Malaise	FAERS: 2		SIDER US FAERS
24	Pain	FAERS: 2		OFFSIDES SIDER US FAERS
25	Abasia	FAERS: 1		OFFSIDES US FAERS
26	Abdominal Pain	FAERS: 1		OFFSIDES SIDER US FAERS
27	Activities of daily living impaired	FAERS: 1		US FAERS
28	Agranulocytosis	FAERS: 1		SIDER US FAERS
29	Angioedema	FAERS: 1		US FAERS
30	Apparent death	FAERS: 1		US FAERS
31	Arthropathy	FAERS: 1		US FAERS
32	Bladder discomfort	FAERS: 1		US FAERS
33	Blood electrolytes decreased	FAERS: 1		OFFSIDES US FAERS
34	Blood glucose increased	FAERS: 1		US FAERS
35	Blood urea increased	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES SIDER US FAERS
36	Blood urine present	FAERS: 1		US FAERS
37	Bradycardia	FAERS: 1		OFFSIDES US FAERS
38	Cellulitis	FAERS: 1		OFFSIDES US FAERS
39	Chest discomfort	FAERS: 1		US FAERS
40	Dysuria	FAERS: 1		US FAERS
41	Electrolyte imbalance	FAERS: 1		US FAERS
42	Eosinophilia	FAERS: 1		US FAERS
43	Erythema	FAERS: 1		OFFSIDES US FAERS
44	Eye irritation	FAERS: 1		US FAERS
45	Fibromyalgia	FAERS: 1		US FAERS
46	Fluid overload	FAERS: 1		OFFSIDES US FAERS
47	Gait inability	FAERS: 1		US FAERS
48	Gout	FAERS: 1		OFFSIDES US FAERS
49	Hepatitis	FAERS: 1 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
50	Hypersensitivity	FAERS: 1		SIDER US FAERS
51	Incorrect dose administered	FAERS: 1		US FAERS
52	Lethargy	FAERS: 1		OFFSIDES SIDER US FAERS
53	Medical diet	FAERS: 1		US FAERS
54	Medication Error	FAERS: 1		US FAERS
55	Metabolic alkalosis	FAERS: 1		US FAERS
56	Neutropenia	FAERS: 1		US FAERS
57	Oropharyngeal pain	FAERS: 1		OFFSIDES SIDER US FAERS
58	Rash erythematous	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
59	Reaction to drug excipients	FAERS: 1		US FAERS
60	Stevens-Johnson Syndrome	FAERS: 1	25811541	CTD SIDER US FAERS
61	Terminal state	FAERS: 1		US FAERS
62	Therapeutic response unexpected with drug substitution	FAERS: 1		US FAERS
63	Tremor	FAERS: 1		US FAERS
64	Urticaria	FAERS: 1		SIDER US FAERS
65	Ventricular Fibrillation	FAERS: 1		OFFSIDES US FAERS
66	Weight decreased	FAERS: 1		US FAERS
67	White blood cell count decreased	FAERS: 1		US FAERS
68	Abdominal Infection			OFFSIDES
69	Abdominal bloating			SIDER
70	Abdominal discomfort			OFFSIDES SIDER
71	Abdominal sepsis			OFFSIDES
72	Abdominal wall infection			OFFSIDES
73	Abnormal vision			OFFSIDES
74	Abscess			OFFSIDES
75	Achlorhydria			OFFSIDES
76	Acid reflux			OFFSIDES
77	Actinomycosis			OFFSIDES
78	Acute Coronary Syndrome			OFFSIDES
79	Acute bronchitis			OFFSIDES
80	Acute myocardial infarction			OFFSIDES
81	Acute prerenal failure			OFFSIDES
82	Acute respiratory failure			OFFSIDES
83	Acute sinusitis			OFFSIDES
84	Adenitis			OFFSIDES
85	Adenocarcinoma			OFFSIDES
86	Adenoma			OFFSIDES
87	Adrenal mass			OFFSIDES
88	Agitation			SIDER
89	Alanine Aminotransferase Increased			OFFSIDES
90	Albumin globulin ratio decreased			OFFSIDES
91	Alcohol abuse			OFFSIDES
92	Alkalosis		635611	CTD
93	Alveolitis			OFFSIDES
94	Alveoloplasty			OFFSIDES
95	Ammonia increased			OFFSIDES
96	Amyloidosis			OFFSIDES
97	Anal Fistula			OFFSIDES
98	Angioplasty			OFFSIDES
99	Anhedonia			OFFSIDES
100	Anorexia		11572578	CTD OFFSIDES SIDER
101	Anoxic Encephalopathy			OFFSIDES
102	Anticoagulation drug level above therapeutic			OFFSIDES
103	Antiviral drug level above therapeutic			OFFSIDES
104	Anxiety			OFFSIDES SIDER
105	Aortic bypass			OFFSIDES
106	Aortic valve calcification			OFFSIDES
107	Apathy			OFFSIDES
108	Arteriosclerosis			OFFSIDES
109	Arteriovenous graft thrombosis			OFFSIDES
110	Arthralgia			SIDER
111	Arthritis			OFFSIDES
112	Artificial crown procedure			OFFSIDES
113	Ascites infection			OFFSIDES
114	Ascites			OFFSIDES
115	Aspiration Pneumonia			OFFSIDES
116	Asthma			OFFSIDES
117	Asymptomatic bacteriuria			OFFSIDES
118	Ataxia			OFFSIDES
119	Atelectasis			OFFSIDES
120	Atrial Flutter			OFFSIDES
121	Atrial natriuretic peptide increased			OFFSIDES
122	Atrial tachycardia			OFFSIDES
123	Axonal neuropathy			OFFSIDES
124	Back disorder			OFFSIDES
125	Bacteria urine identified			OFFSIDES
126	Basal cell carcinoma			OFFSIDES
127	Bile Duct Stenosis			OFFSIDES
128	Bladder Neoplasm			OFFSIDES
129	Bladder cancer stage IV			OFFSIDES
130	Bladder neoplasm surgery			OFFSIDES
131	Blepharoptosis			OFFSIDES
132	Blepharospasm			OFFSIDES
133	Blood Glucose			OFFSIDES
134	Blood albumin decreased			OFFSIDES
135	Blood alkaline phosphatase increased			OFFSIDES
136	Blood amylase decreased			OFFSIDES
137	Blood bicarbonate			OFFSIDES
138	Blood calcium abnormal			OFFSIDES
139	Blood chloride abnormal			OFFSIDES
140	Blood chloride decreased			OFFSIDES
141	Blood creatine phosphokinase MB increased			OFFSIDES
142	Blood creatinine increased	Canada Vigilance: 1		Canada Vigilance OFFSIDES
143	Blood electrolytes abnormal			OFFSIDES
144	Blood fibrinogen increased			OFFSIDES
145	Blood glucose abnormal			OFFSIDES
146	Blood glucose decreased			OFFSIDES
147	Blood glucose fluctuation			OFFSIDES
148	Blood magnesium decreased			OFFSIDES
149	Blood magnesium increased			OFFSIDES
150	Blood pH decreased			OFFSIDES
151	Blood potassium increased			OFFSIDES
152	Blood pressure fluctuation			OFFSIDES
153	Blood pressure immeasurable			OFFSIDES
154	Blood sodium			OFFSIDES
155	Blood triglycerides increased			OFFSIDES
156	Blood urea abnormal			OFFSIDES
157	Blood uric acid			OFFSIDES
158	Blurred vision			OFFSIDES
159	Bone density decreased			OFFSIDES
160	Bone fissure			OFFSIDES
161	Bone lesion			OFFSIDES
162	Bone pain			OFFSIDES
163	Borderline Personality Disorder			OFFSIDES
164	Botulism			OFFSIDES
165	Brain Death			OFFSIDES
166	Brain natriuretic peptide increased			OFFSIDES
167	Breast hyperplasia			OFFSIDES
168	Breast tenderness			OFFSIDES
169	Bronchitis			OFFSIDES
170	Bronchopneumonia			OFFSIDES
171	Bronchoscopy abnormal			OFFSIDES
172	Bruxism			OFFSIDES
173	Calcium deficiency			OFFSIDES
174	Cardiac Hypertrophy			OFFSIDES
175	Cardioactive drug level			OFFSIDES
176	Cardioactive drug level above therapeutic			OFFSIDES
177	Cardioactive drug level below therapeutic			OFFSIDES
178	Cardioactive drug level increased			OFFSIDES
179	Carotid artery aneurysm			OFFSIDES
180	Carotid bruit			OFFSIDES
181	Cataract operation			OFFSIDES
182	Cataract			OFFSIDES
183	Catheter related complication			OFFSIDES
184	Central nervous system lesion			OFFSIDES
185	Cerebral Infarction	Canada Vigilance: 1		Canada Vigilance
186	Cerebral atrophy			OFFSIDES
187	Cervical myelopathy			OFFSIDES
188	Chemotherapeutic drug level increased			OFFSIDES
189	Chest Pain			OFFSIDES SIDER
190	Chills			SIDER
191	Choking sensation			OFFSIDES
192	Choking			OFFSIDES
193	Cholecystitis infective			OFFSIDES
194	Cholecystitis			OFFSIDES
195	Cholestasis		11572578	CTD
196	Chronic Fatigue Syndrome			OFFSIDES
197	Chronic Obstructive Airway Disease			OFFSIDES
198	Chronic respiratory failure			OFFSIDES
199	Circumstance or information capable of leading to medication error			OFFSIDES
200	Cirrhosis			OFFSIDES
201	Claustrophobia			OFFSIDES
202	Clostridium colitis			OFFSIDES
203	Clubbing			OFFSIDES
204	Cold sweat			OFFSIDES
205	Concomitant disease progression			OFFSIDES
206	Confabulation			OFFSIDES
207	Congenital heart disease			OFFSIDES
208	Congenital tricuspid valve incompetence			OFFSIDES
209	Continuous Positive Airway Pressure			OFFSIDES
210	Cor pulmonale			OFFSIDES
211	Coronary angioplasty			OFFSIDES
212	Coronary artery insufficiency			OFFSIDES
213	Craniotomy			OFFSIDES
214	Culture positive			OFFSIDES
215	Cyanopsia			OFFSIDES
216	Cyanosis			OFFSIDES
217	Deafness Neurosensory			OFFSIDES
218	Deafness			OFFSIDES
219	Debridement			OFFSIDES
220	Delusion of replacement			OFFSIDES
221	Delusional disorder, unspecified type			OFFSIDES
222	Demyelination			OFFSIDES
223	Dental Fistula			OFFSIDES
224	Dental abscess			OFFSIDES
225	Dental prosthesis placement			OFFSIDES
226	Depressed mood			OFFSIDES
227	Dermatitis			SIDER
228	Dermatomyositis			OFFSIDES
229	Device dislocation			OFFSIDES
230	Device related infection			OFFSIDES
231	Diabetes			OFFSIDES
232	Diabetes mellitus inadequate control			OFFSIDES
233	Diabetic Nephropathy			OFFSIDES
234	Diabetic Retinopathy			OFFSIDES
235	Diabetic ulcer			OFFSIDES
236	Diarrhea			OFFSIDES
237	Diastolic dysfunction			OFFSIDES
238	Discomfort			SIDER
239	Disease Progression			OFFSIDES
240	Disease recurrence			OFFSIDES
241	Diverticulosis			OFFSIDES
242	Diverticulum			OFFSIDES
243	Drowning			OFFSIDES
244	Drowsiness			SIDER
245	Drug Tolerance			OFFSIDES
246	Drug addict			OFFSIDES
247	Drug toxicity			OFFSIDES
248	Drug withdrawal headache			OFFSIDES
249	Dry skin			SIDER
250	Dysgeusia			SIDER
251	Dyspepsia			OFFSIDES SIDER
252	Dysphasia			OFFSIDES
253	Ear discharge			OFFSIDES
254	Eclampsia			OFFSIDES
255	Economic problem			OFFSIDES
256	Edema		1276698	CTD
257	Ejection fraction abnormal			OFFSIDES
258	Electrocardiogram ST-T change			OFFSIDES
259	Electrocardiogram ST-T segment abnormal			OFFSIDES
260	Electrocardiogram poor R-wave progression			OFFSIDES
261	Electromechanical dissociation			OFFSIDES
262	Embolism			OFFSIDES
263	Emotional disorder			OFFSIDES
264	Emotional distress			OFFSIDES
265	Endodontic procedure			OFFSIDES
266	Endometrial disorder			OFFSIDES
267	Enteritis			OFFSIDES
268	Enterococcal infection			OFFSIDES
269	Epididymitis			OFFSIDES
270	Epigastric distress			SIDER
271	Epistaxis			OFFSIDES SIDER
272	Erectile dysfunction			SIDER
273	Erosive gastritis			OFFSIDES
274	Erythema Multiforme			SIDER
275	Escherichia infection			OFFSIDES
276	Escherichia urinary tract infection			OFFSIDES
277	Eustachian tube disorder			OFFSIDES
278	Excoriation			OFFSIDES
279	Exposure to toxic agent			OFFSIDES
280	Extremity contracture			OFFSIDES
281	Facial Neuralgia			OFFSIDES
282	Factor V Leiden mutation			OFFSIDES
283	Fat necrosis			OFFSIDES
284	Febrile Neutropenia			OFFSIDES
285	Femoral arterial stenosis			OFFSIDES
286	Fistula repair			OFFSIDES
287	Flank Pain			OFFSIDES
288	Flatulence			SIDER
289	Fluid imbalance			OFFSIDES
290	Frostbite			OFFSIDES
291	Gallop rhythm present			OFFSIDES
292	Gangrene			OFFSIDES
293	Gastric infection			OFFSIDES
294	Gastric ulcer			OFFSIDES
295	Gastroenteritis			OFFSIDES
296	Gastrointestinal Pain			SIDER
297	Gaze palsy			OFFSIDES
298	General physical health deterioration			OFFSIDES
299	General symptom			OFFSIDES
300	Glaucoma			OFFSIDES
301	Globulin abnormal			OFFSIDES
302	Globulinuria			OFFSIDES
303	Glomerulonephritis			OFFSIDES
304	Glycosuria			SIDER
305	Goiter			OFFSIDES
306	Graft infection			OFFSIDES
307	Granulocytosis			OFFSIDES
308	Haematotoxicity			OFFSIDES
309	Hay fever			OFFSIDES
310	Hemothorax			OFFSIDES
311	Hepatic congestion			OFFSIDES
312	Hepatojugular reflux			OFFSIDES
313	Hernia obstructive			OFFSIDES
314	Hernia			OFFSIDES
315	Hidradenitis			OFFSIDES
316	Hydronephrosis			OFFSIDES
317	Hypercalcemia		1928234	CTD
318	Hypercapnia			OFFSIDES
319	Hyperkeratosis			OFFSIDES
320	Hyperosmolar state			OFFSIDES
321	Hyperparathyroidism			OFFSIDES
322	Hyperpigmentation			OFFSIDES
323	Hypertensive heart disease			OFFSIDES
324	Hypertrophic Cardiomyopathy			OFFSIDES
325	Hypoaesthesia facial			OFFSIDES
326	Hypogonadism			OFFSIDES
327	Hypokalemia		6860532 6883959	CTD
328	Hyponatremia		635611	CTD
329	Hypophagia			OFFSIDES
330	Hypoxia			OFFSIDES
331	Hysterectomy			OFFSIDES
332	Iliac artery stenosis			OFFSIDES
333	Immunosuppressant drug level decreased			OFFSIDES
334	Impaired gastric emptying			OFFSIDES
335	Impaired self-care			OFFSIDES
336	Impetigo			OFFSIDES
337	Implant site discharge			OFFSIDES
338	Implant site infection			OFFSIDES
339	Implant site reaction			OFFSIDES
340	Implantable defibrillator insertion			OFFSIDES
341	Incontinence			OFFSIDES
342	Incorrect drug administration rate			OFFSIDES
343	Infection			OFFSIDES
344	Infertility			OFFSIDES
345	Infusion site mobility decreased			OFFSIDES
346	Infusion site pain			OFFSIDES
347	Injection site erythema			OFFSIDES
348	Insulin Resistance			OFFSIDES
349	Insulin-requiring type 2 diabetes mellitus			OFFSIDES
350	Intermittent Claudication			OFFSIDES
351	Intervertebral Disc Degeneration			OFFSIDES
352	Intestinal Obstruction			OFFSIDES
353	Iron Overload			OFFSIDES
354	Joint Range of Motion Decreased			OFFSIDES
355	Jugular vein distension			OFFSIDES
356	Keratitis sicca			OFFSIDES
357	Kidney Failure			OFFSIDES
358	Laceration			OFFSIDES
359	Lassitude			SIDER
360	Left Ventricular Hypertrophy			OFFSIDES
361	Left atrial dilatation			OFFSIDES
362	Legionella			OFFSIDES
363	Leukoencephalopathy			OFFSIDES
364	Leukopenia			SIDER
365	Lightheadedness			SIDER
366	Limb injury			OFFSIDES
367	Localised intraabdominal fluid collection			OFFSIDES
368	Lumbar radiculopathy			OFFSIDES
369	Lymphangitis			OFFSIDES
370	Macrocytosis			OFFSIDES
371	Magnesium Deficiency			OFFSIDES
372	Malabsorption			OFFSIDES
373	Malignant Hypertension			OFFSIDES
374	Malignant neoplasm progression			OFFSIDES
375	Mastoiditis			OFFSIDES
376	Mediastinitis			OFFSIDES
377	Mental impairment			OFFSIDES
378	Mental status changes			OFFSIDES
379	Metabolic acidosis			OFFSIDES
380	Metastatic Renal Cell Carcinoma			OFFSIDES
381	Microalbuminuria			OFFSIDES
382	Micrographic skin surgery			OFFSIDES
383	Milk-Alkali Syndrome			OFFSIDES
384	Moaning			OFFSIDES
385	Multiple Myeloma			OFFSIDES
386	Multiple Sclerosis			OFFSIDES
387	Multiple allergies			OFFSIDES
388	Muscle Cramp		1276698	CTD
389	Muscle Weakness			OFFSIDES
390	Muscular Dystrophy			OFFSIDES
391	Musculoskeletal Pain			OFFSIDES
392	Musculoskeletal discomfort			OFFSIDES SIDER
393	Musculoskeletal stiffness			OFFSIDES
394	Myalgia	Canada Vigilance: 1		Canada Vigilance
395	Myelodysplasia			OFFSIDES
396	Myomectomy			OFFSIDES
397	Myosclerosis			OFFSIDES
398	Nephrogenic Fibrosing Dermopathy			OFFSIDES
399	Nephrotic Syndrome			OFFSIDES
400	Nervousness			SIDER
401	Neuropathic ulcer			OFFSIDES
402	Neuropathy			SIDER
403	Neutropenic sepsis			OFFSIDES
404	Nocturia			OFFSIDES SIDER
405	Non-small cell lung cancer stage I			OFFSIDES
406	Nystagmus			OFFSIDES
407	Occult blood positive			OFFSIDES
408	Open reduction of fracture			OFFSIDES
409	Oral mucosal erythema			OFFSIDES
410	Orchitis			OFFSIDES
411	Oropharyngeal discomfort			SIDER
412	Orthopnea			OFFSIDES
413	Osteolysis			OFFSIDES
414	Osteoma			OFFSIDES
415	Osteomyelitis			OFFSIDES
416	Osteoradionecrosis			OFFSIDES
417	Osteosclerosis			OFFSIDES
418	Oxygen supplementation			OFFSIDES
419	PCO2 decreased			OFFSIDES
420	PCO2 increased			OFFSIDES
421	PO2 decreased			OFFSIDES
422	Pacemaker complication			OFFSIDES
423	Pain of skin			OFFSIDES
424	Pallor			OFFSIDES
425	Palpitations			SIDER
426	Paranasal sinus hypersecretion			OFFSIDES
427	Paranoia			OFFSIDES
428	Partner stress			OFFSIDES
429	Patellofemoral Pain Syndrome			OFFSIDES
430	Pedal pulse decreased			OFFSIDES
431	Pelvic fluid collection			OFFSIDES
432	Pelvic mass			OFFSIDES
433	Performance status decreased			OFFSIDES
434	Pericardial effusion			OFFSIDES
435	Peripheral arterial occlusive disease			OFFSIDES
436	Peripheral embolism			OFFSIDES
437	Perirectal abscess			OFFSIDES
438	Peritoneal Dialysis			OFFSIDES
439	Peritonitis			OFFSIDES
440	Petechiae			SIDER
441	Phlebitis			OFFSIDES
442	Phonophobia			OFFSIDES
443	Plasmapheresis			OFFSIDES
444	Pneumoperitoneum			OFFSIDES
445	Polyarteritis Nodosa		6126318	CTD
446	Poor peripheral circulation			OFFSIDES
447	Poor personal hygiene			OFFSIDES
448	Post procedural cellulitis			OFFSIDES
449	Primary sequestrum			OFFSIDES
450	Productive Cough			OFFSIDES
451	Pseudoporphyria			OFFSIDES
452	Psoriasis			OFFSIDES
453	Pulmonary Hypertension			OFFSIDES
454	Pulmonary Valve Stenosis			OFFSIDES
455	Pulmonary arterial hypertension			OFFSIDES
456	Pulmonary arterial pressure increased			OFFSIDES
457	Pulmonary congestion			OFFSIDES
458	Pulmonary necrosis			OFFSIDES
459	Pulmonary vascular disorder			OFFSIDES
460	Purpura			SIDER
461	Purulent discharge			OFFSIDES
462	Pustular psoriasis			OFFSIDES
463	Pyelonephritis			OFFSIDES
464	QRS axis abnormal			OFFSIDES
465	Quality of life decreased			OFFSIDES
466	Rales			OFFSIDES
467	Removal of transplanted organ			OFFSIDES
468	Renal Artery Stenosis			OFFSIDES
469	Renal Colic			OFFSIDES
470	Renal cyst			OFFSIDES
471	Renal embolism			OFFSIDES
472	Renal mass			OFFSIDES
473	Renal tubular necrosis			OFFSIDES
474	Respiratory Failure			OFFSIDES
475	Restrictive cardiomyopathy			OFFSIDES
476	Reticulocyte count increased			OFFSIDES
477	Rhabdomyolysis			OFFSIDES
478	Rheumatoid factor increased			OFFSIDES
479	Rhinitis			OFFSIDES
480	Rhinorrhea			OFFSIDES
481	Rhonchi			OFFSIDES
482	Right Ventricular Hypertrophy			OFFSIDES
483	Right atrial dilatation			OFFSIDES
484	Seizures		1276698	CTD
485	Septic Shock			OFFSIDES
486	Serum urea increased			SIDER
487	Shock			SIDER
488	Sick Sinus Syndrome			OFFSIDES
489	Sinus bradycardia			OFFSIDES
490	Sinus polyp			OFFSIDES
491	Sinusitis			OFFSIDES
492	Skin Induration			OFFSIDES
493	Skin hypertrophy			OFFSIDES
494	Skin laceration			OFFSIDES
495	Skin lesion			OFFSIDES
496	Skin necrosis			OFFSIDES SIDER
497	Skin tightness			OFFSIDES
498	Snoring			OFFSIDES
499	Somnolence			SIDER
500	Spinal column stenosis			OFFSIDES
501	Spondylolisthesis			OFFSIDES
502	Spondylolysis			OFFSIDES
503	Spontaneous penile erection			OFFSIDES
504	Sputum culture positive			OFFSIDES
505	Staring			OFFSIDES
506	Stasis dermatitis			OFFSIDES
507	Stool analysis abnormal			OFFSIDES
508	Subcutaneous nodule			OFFSIDES
509	Submandibular mass			OFFSIDES
510	Sudden Cardiac Death			OFFSIDES
511	Sudden death			OFFSIDES
512	Supraventricular tachycardia			OFFSIDES
513	Sweat gland infection			OFFSIDES
514	Swelling			SIDER
515	Synovial Cyst			OFFSIDES
516	Temporal Arteritis			OFFSIDES
517	Tension			SIDER
518	Thrombocytopenia			SIDER
519	Thrombophlebitis			OFFSIDES
520	Thyroidectomy			OFFSIDES
521	Tinea Pedis			OFFSIDES
522	Tinnitus			SIDER
523	Tobacco user			OFFSIDES
524	Tooth Extraction			OFFSIDES
525	Tooth repair			OFFSIDES
526	Toxic Epidermal Necrolysis			SIDER
527	Transfusion Reaction			OFFSIDES
528	Troponin I increased			OFFSIDES
529	Troponin increased			OFFSIDES
530	Ulcer			OFFSIDES
531	Umbilical hernia			OFFSIDES
532	Unevaluable event			OFFSIDES
533	Unresponsive to stimuli			OFFSIDES
534	Urethral Obstruction			OFFSIDES
535	Urinary Tract Pain			OFFSIDES
536	Urinary tract infection pseudomonal			OFFSIDES
537	Urine arsenic increased			OFFSIDES
538	Urine flow decreased			OFFSIDES
539	Uterine Cancer			OFFSIDES
540	Vaginal Prolapse			OFFSIDES
541	Vascular calcification			OFFSIDES
542	Vascular purpura			SIDER
543	Vasculitis, Leukocytoclastic, Cutaneous		1946137	CTD
544	Venous Insufficiency			OFFSIDES
545	Venous Thrombosis			SIDER
546	Venous stasis			OFFSIDES
547	Venous thrombosis limb			OFFSIDES
548	Ventricular hypokinesia			OFFSIDES
549	Vertigo			SIDER
550	Vitamin B 12 Deficiency			OFFSIDES
551	Waist circumference increased			OFFSIDES
552	Walking aid user			OFFSIDES
553	Weight Gain			OFFSIDES
554	Wound Infection			OFFSIDES
555	Wound infection staphylococcal			OFFSIDES
556	Wrong drug administered			OFFSIDES
557	Xanthopsia			OFFSIDES
558	effusion			OFFSIDES
559	jaundice		11572578	CTD

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