Diane
(RWYFURDDADFSHT-RBBHPAOJSA-N)
Structure
- SMILES
- CC(=O)O[C@@]1(CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2C=C(C2=CC(=O)[C@H]3C([C@]12C)C3)Cl)C(=O)C.C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCc2c1ccc(c2)O
- Molecular Formula:
- C44H53ClO6
- Molecular Weight:
- 713.341
- Log P:
- 8.2202
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 2
- TPSA:
- 100.9
- CAS Number(s):
- 60528-19-0
Synonym(s)
1.
Diane
External Link(s)
| PubChem Compound | 107694 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Headache | FAERS: 2 Canada Vigilance: 12 | Canada Vigilance SIDER US FAERS | |
| 2 | Abdominal Pain | Canada Vigilance: 4 | Canada Vigilance SIDER | |
| 3 | Accidental overdose | Canada Vigilance: 1 | Canada Vigilance | |
| 4 | Acne | Canada Vigilance: 2 | Canada Vigilance | |
| 5 | Acute kidney injury | Canada Vigilance: 1 | Canada Vigilance | |
| 6 | Alanine Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance | |
| 7 | Alopecia | Canada Vigilance: 6 | Canada Vigilance | |
| 8 | Amenorrhea | OFFSIDES | ||
| 9 | Anger | Canada Vigilance: 1 | Canada Vigilance | |
| 10 | Anorectal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 11 | Anxiety | Canada Vigilance: 6 | Canada Vigilance | |
| 12 | Apathy | Canada Vigilance: 1 | Canada Vigilance | |
| 13 | Arthralgia | Canada Vigilance: 1 | Canada Vigilance | |
| 14 | Aspartate Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance | |
| 15 | Asthenia | Canada Vigilance: 1 | Canada Vigilance | |
| 16 | Autoimmune thyroiditis | OFFSIDES | ||
| 17 | Back Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 18 | Blindness | Canada Vigilance: 1 | Canada Vigilance | |
| 19 | Blood creatinine increased | Canada Vigilance: 2 | Canada Vigilance | |
| 20 | Bone pain | OFFSIDES | ||
| 21 | Bradycardia | OFFSIDES | ||
| 22 | Brain Death | Canada Vigilance: 3 | Canada Vigilance | |
| 23 | Brain Hypoxia | Canada Vigilance: 2 | Canada Vigilance | |
| 24 | Breast tenderness | SIDER | ||
| 25 | Cardiac Arrest | Canada Vigilance: 5 | Canada Vigilance | |
| 26 | Cardiac Tamponade | OFFSIDES | ||
| 27 | Cerebral Infarction | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Cerebrovascular accident | Canada Vigilance: 12 | Canada Vigilance | |
| 29 | Cervix carcinoma | Canada Vigilance: 2 | Canada Vigilance | |
| 30 | Chest Pain | Canada Vigilance: 9 | Canada Vigilance OFFSIDES | |
| 31 | Chest discomfort | Canada Vigilance: 2 | Canada Vigilance | |
| 32 | Chloasma | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Complications of maternal exposure to therapeutic drugs | OFFSIDES | ||
| 34 | Compression fracture | OFFSIDES | ||
| 35 | Congenital hypertrichosis | OFFSIDES | ||
| 36 | Contact lens intolerance | SIDER | ||
| 37 | Crying | Canada Vigilance: 3 | Canada Vigilance | |
| 38 | Cytolytic hepatitis | OFFSIDES | ||
| 39 | Deep Vein Thrombosis | Canada Vigilance: 12 | Canada Vigilance | |
| 40 | Depressed mood | Canada Vigilance: 4 | Canada Vigilance SIDER | |
| 41 | Dermatitis | SIDER | ||
| 42 | Disease recurrence | OFFSIDES | ||
| 43 | Disturbance in sexual arousal | SIDER | ||
| 44 | Dizziness | Canada Vigilance: 3 | Canada Vigilance | |
| 45 | Drug exposure during pregnancy | OFFSIDES | ||
| 46 | Drug ineffective | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Dysarthria | Canada Vigilance: 2 | Canada Vigilance | |
| 48 | Dyschezia | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Ear discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Ectropion | Canada Vigilance: 2 | Canada Vigilance | |
| 51 | Edema | 10857213 | CTD | |
| 52 | Embolism | Canada Vigilance: 2 | Canada Vigilance | |
| 53 | Emotional disorder | Canada Vigilance: 2 | Canada Vigilance | |
| 54 | Epilepsy | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Epistaxis | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Erythema Multiforme | SIDER | ||
| 57 | Erythema Nodosum | SIDER | ||
| 58 | Erythema | Canada Vigilance: 1 | Canada Vigilance | |
| 59 | Facial Neuralgia | OFFSIDES | ||
| 60 | Familial Mediterranean Fever | OFFSIDES | ||
| 61 | Fatigue | Canada Vigilance: 4 | Canada Vigilance | |
| 62 | Gastrointestinal Diseases | 10857213 | CTD | |
| 63 | Gastrointestinal Pain | SIDER | ||
| 64 | Hemiparesis | Canada Vigilance: 2 | Canada Vigilance | |
| 65 | Hepatitis | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 66 | Hepatomegaly | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Hepatotoxicity | OFFSIDES | ||
| 68 | Hypersensitivity | SIDER | ||
| 69 | Hypertrophy of Breast | SIDER | ||
| 70 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Injection site dermatitis | OFFSIDES | ||
| 72 | Injection site erythema | OFFSIDES | ||
| 73 | Injection site pruritus | OFFSIDES | ||
| 74 | Intentional product misuse | Canada Vigilance: 1 | Canada Vigilance | |
| 75 | Intracranial mass | Canada Vigilance: 1 | Canada Vigilance | |
| 76 | Leukopenia neonatal | OFFSIDES | ||
| 77 | Limb discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 78 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Malnutrition | SIDER | ||
| 80 | Metrorrhagia | Canada Vigilance: 2 | Canada Vigilance | |
| 81 | Migraine Disorders | 10857213 | CTD | |
| 82 | Migraine with Aura | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Mood Disorders | 10857213 | CTD | |
| 84 | Mood swings | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 85 | Muscle tightness | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Mutism | Canada Vigilance: 1 | Canada Vigilance | |
| 87 | Myalgia | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Myelodysplasia | OFFSIDES | ||
| 89 | Myocardial Infarction | Canada Vigilance: 2 | Canada Vigilance | |
| 90 | Myocarditis | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Myopia | OFFSIDES | ||
| 92 | Nausea | Canada Vigilance: 7 | Canada Vigilance SIDER | |
| 93 | Nerve injury | Canada Vigilance: 1 | Canada Vigilance | |
| 94 | Neutropenia | Canada Vigilance: 1 | Canada Vigilance | |
| 95 | Osteolysis | OFFSIDES | ||
| 96 | Osteopenia | OFFSIDES | ||
| 97 | Osteosclerosis | OFFSIDES | ||
| 98 | Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 99 | Palpitations | Canada Vigilance: 5 | Canada Vigilance | |
| 100 | Pelvic Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 101 | Perianal erythema | Canada Vigilance: 1 | Canada Vigilance | |
| 102 | Pericardial effusion | OFFSIDES | ||
| 103 | Pericarditis | OFFSIDES | ||
| 104 | Peripheral swelling | Canada Vigilance: 3 | Canada Vigilance | |
| 105 | Phlebitis | Canada Vigilance: 2 | Canada Vigilance OFFSIDES | |
| 106 | Pleuritic pain | Canada Vigilance: 1 | Canada Vigilance | |
| 107 | Pregnancy on oral contraceptive | Canada Vigilance: 3 | Canada Vigilance OFFSIDES | |
| 108 | Pruritus | Canada Vigilance: 1 | Canada Vigilance | |
| 109 | Pulmonary Embolism | Canada Vigilance: 23 | Canada Vigilance | |
| 110 | Pulmonary thrombosis | Canada Vigilance: 1 | Canada Vigilance | |
| 111 | Quadriplegia | Canada Vigilance: 1 | Canada Vigilance | |
| 112 | Secretion discharge | Canada Vigilance: 1 | Canada Vigilance | |
| 113 | Septic Shock | OFFSIDES | ||
| 114 | Skin lesion | Canada Vigilance: 1 | Canada Vigilance | |
| 115 | Somnolence | Canada Vigilance: 1 | Canada Vigilance | |
| 116 | Sopor | OFFSIDES | ||
| 117 | Stillbirth | Canada Vigilance: 1 | Canada Vigilance | |
| 118 | Stress | Canada Vigilance: 2 | Canada Vigilance | |
| 119 | Syncope | Canada Vigilance: 1 | Canada Vigilance | |
| 120 | Tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 121 | Thalamic infarction | Canada Vigilance: 1 | Canada Vigilance | |
| 122 | Thoracic Outlet Syndrome | OFFSIDES | ||
| 123 | Thrombocytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 124 | Thrombophlebitis | Canada Vigilance: 3 | Canada Vigilance | |
| 125 | Thrombosis | Canada Vigilance: 7 | Canada Vigilance | |
| 126 | Urticaria | SIDER | ||
| 127 | Uterine Cancer | Canada Vigilance: 2 | Canada Vigilance | |
| 128 | Uterine Polyp | Canada Vigilance: 2 | Canada Vigilance | |
| 129 | Vaginal Discharge | SIDER | ||
| 130 | Vascular dissection | Canada Vigilance: 1 | Canada Vigilance | |
| 131 | Venous Thrombosis | Canada Vigilance: 2 | Canada Vigilance | |
| 132 | Ventricular arrhythmia | Canada Vigilance: 1 | Canada Vigilance | |
| 133 | Visual Impairment | Canada Vigilance: 4 | Canada Vigilance | |
| 134 | Vomiting | Canada Vigilance: 4 | Canada Vigilance SIDER | |
| 135 | Vulvovaginal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 136 | Weight decreased | SIDER | ||
| 137 | nervous system disorder | Canada Vigilance: 1 | Canada Vigilance SIDER |
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