MetaADEDB 2.0 @ LMMD
Triiodothyronine
(AUYYCJSJGJYCDS-LBPRGKRZSA-N)
Structure
SMILES
OC(=O)[C@H](Cc1cc(I)c(c(c1)I)Oc1ccc(c(c1)I)O)N
Type(s)
Approved; Vet_approved
ATC code(s)
H03AA02; H03AA03
Molecular Formula:
C15H12I3NO4
Molecular Weight:
650.973
Log P:
4.6530
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
3
TPSA:
92.78
CAS Number(s):
5714-08-9; 6893-02-3; 1823692
Synonym(s)
1.
Triiodothyronine
2.
Liothyronine
3.
T3 Thyroid Hormone
4.
3,3',5-Triiodothyronine
5.
Cytomel
6.
Liothyronine Sodium
7.
Thyroid Hormone, T3
External Link(s)
MeSHD014284
PubChem Compound5920
7048703
BindingDB18860
ChEBI18258
533015
CHEMBLCHEMBL1544
DrugBankDB00279
DrugCentral1585
IUPHAR/BPS Guide to PHARMACOLOGY2634
KEGGdr:D08128
cpd:C02465
Therapeutic Target DatabaseD0D8QI
D0S6JG
ZINC3830999
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 21OFFSIDES
US FAERS
2HeadacheFAERS: 15US FAERS
3FatigueFAERS: 12OFFSIDES
US FAERS
4Product substitution issueFAERS: 12US FAERS
5HyperthyroidismFAERS: 91513203
12516873
23391542		CTD
US FAERS
6MalaiseFAERS: 8US FAERS
7PalpitationsFAERS: 8US FAERS
8AlopeciaFAERS: 6OFFSIDES
US FAERS
9AnxietyFAERS: 5OFFSIDES
US FAERS
10Drug abuseFAERS: 5US FAERS
11ArthralgiaFAERS: 4US FAERS
12Atrial FibrillationFAERS: 4US FAERS
13DizzinessFAERS: 4OFFSIDES
US FAERS
14Feeling abnormalFAERS: 4OFFSIDES
US FAERS
15HypersensitivityFAERS: 4US FAERS
16Abdominal discomfortFAERS: 3OFFSIDES
US FAERS
17Adverse eventFAERS: 3US FAERS
18AstheniaFAERS: 3OFFSIDES
US FAERS
19Chest PainFAERS: 3OFFSIDES
US FAERS
20HypothyroidismFAERS: 310580751
17634708		CTD
US FAERS
21LethargyFAERS: 3OFFSIDES
US FAERS
22MyalgiaFAERS: 3US FAERS
23NauseaFAERS: 3OFFSIDES
US FAERS
24OverdoseFAERS: 3OFFSIDES
US FAERS
25PainFAERS: 3OFFSIDES
US FAERS
26Product quality issueFAERS: 3US FAERS
27Reaction to excipientFAERS: 3US FAERS
28Thyrotoxic periodic paralysisFAERS: 3OFFSIDES
US FAERS
29VomitingFAERS: 3US FAERS
30Blood thyroid stimulating hormone decreasedFAERS: 2US FAERS
31Bone painFAERS: 2OFFSIDES
US FAERS
32BradycardiaFAERS: 22483802CTD
US FAERS
33Cardiac ArrestFAERS: 2US FAERS
34DeliriumFAERS: 2US FAERS
35Dry skinFAERS: 2OFFSIDES
US FAERS
36Eye irritationFAERS: 2US FAERS
37FlatulenceFAERS: 2OFFSIDES
US FAERS
38Pharmaceutical product complaintFAERS: 2OFFSIDES
US FAERS
39Product compounding quality issueFAERS: 2US FAERS
40Reaction to drug excipientsFAERS: 2US FAERS
41UrticariaFAERS: 2US FAERS
42Wrong technique in product usage processFAERS: 2US FAERS
43Abnormal weight gainFAERS: 1US FAERS
44Atrial FlutterFAERS: 1OFFSIDES
US FAERS
45Blood thyroid stimulating hormone abnormalFAERS: 1OFFSIDES
US FAERS
46Blood thyroid stimulating hormone increasedFAERS: 1OFFSIDES
US FAERS
47CataractFAERS: 1US FAERS
48Chest discomfortFAERS: 1US FAERS
49DeafnessFAERS: 1OFFSIDES
US FAERS
50Depressed Level of ConsciousnessFAERS: 1US FAERS
51Diabetes MellitusFAERS: 1US FAERS
52DiplopiaFAERS: 1OFFSIDES
US FAERS
53Drug level decreasedFAERS: 1US FAERS
54Drug level increasedFAERS: 1US FAERS
55Drug resistanceFAERS: 1US FAERS
56DyspepsiaFAERS: 1OFFSIDES
US FAERS
57EczemaFAERS: 1OFFSIDES
US FAERS
58Epinephrine increasedFAERS: 1US FAERS
59Expired product administeredFAERS: 1US FAERS
60Eye painFAERS: 1OFFSIDES
US FAERS
61Feeling jitteryFAERS: 1US FAERS
62FlushingFAERS: 1US FAERS
63GastritisFAERS: 1US FAERS
64Gastrointestinal PainFAERS: 1US FAERS
65GlaucomaFAERS: 1US FAERS
66Gluten sensitivityFAERS: 1US FAERS
67Hormone level abnormalFAERS: 1OFFSIDES
US FAERS
68Inappropriate schedule of product administrationFAERS: 1US FAERS
69Incorrect dose administeredFAERS: 1OFFSIDES
US FAERS
70Joint stiffnessFAERS: 1OFFSIDES
US FAERS
71Myocardial InfarctionFAERS: 1SIDER
US FAERS
72MyocarditisFAERS: 1US FAERS
73NephrolithiasisFAERS: 1US FAERS
74Nonspecific reactionFAERS: 1US FAERS
75Oropharyngeal discomfortFAERS: 1US FAERS
76Post procedural complicationFAERS: 1US FAERS
77Product formulation issueFAERS: 1US FAERS
78Product friableFAERS: 1US FAERS
79Product preparation errorFAERS: 1US FAERS
80Product solubility abnormalFAERS: 1US FAERS
81Product taste abnormalFAERS: 1US FAERS
82Pulmonary EmbolismFAERS: 1US FAERS
83SinusitisFAERS: 1OFFSIDES
US FAERS
84SluggishnessFAERS: 1US FAERS
85Temperature regulation disorderFAERS: 1US FAERS
86Tension HeadacheFAERS: 1US FAERS
87Therapeutic product effect increasedFAERS: 1US FAERS
88Throat irritationFAERS: 1US FAERS
89Thyroid hormones decreasedFAERS: 1US FAERS
90TinnitusFAERS: 1US FAERS
91TremorFAERS: 1US FAERS
92Tri-iodothyronine free increasedFAERS: 1US FAERS
93AbasiaOFFSIDES
94Abdominal PainOFFSIDES
95Abnormal withdrawal bleedingOFFSIDES
96Abnormalities, Drug-Induced29458080CTD
97Accidental overdoseOFFSIDES
98Acid refluxOFFSIDES
99AcneOFFSIDES
100ActinomycosisOFFSIDES
101Activities of daily living impairedOFFSIDES
102Acute Coronary SyndromeSIDER
103Acute sinusitisOFFSIDES
104Adnexa uteri massOFFSIDES
105AdnexitisOFFSIDES
106AgeusiaOFFSIDES
107Altered bowel functionOFFSIDES
108AmblyopiaOFFSIDES
109AmnesiaOFFSIDES
110AngerOFFSIDES
111Angina PectorisSIDER
112AngioedemaOFFSIDES
113AnhedoniaOFFSIDES
114AnhidrosisOFFSIDES
115Animal biteOFFSIDES
116Ankle FractureOFFSIDES
117Antimicrobial susceptibility test resistantOFFSIDES
118ApathyOFFSIDES
119AphoniaOFFSIDES
120ArthritisOFFSIDES
121ArthrodesisOFFSIDES
122Arthropod biteOFFSIDES
123AsthmaOFFSIDES
124Atrioventricular BlockOFFSIDES
125Back disorderOFFSIDES
126Band neutrophil count increasedOFFSIDES
127Biopsy tongue abnormalOFFSIDES
128BlepharitisOFFSIDES
129Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
130Blood GlucoseOFFSIDES
131Blood chloride increasedOFFSIDES
132Blood cholesterol abnormalOFFSIDES
133Blood glucose decreasedOFFSIDES
134Blood phosphorus decreasedOFFSIDES
135Blood pressure fluctuationOFFSIDES
136Blood thyroid stimulating hormoneOFFSIDES
137Blood urine presentOFFSIDES
138Blurred visionOFFSIDES
139Body TemperatureOFFSIDES
140Body temperature fluctuationOFFSIDES
141Bone density decreasedOFFSIDES
142Bone erosionOFFSIDES
143Bone fragmentationOFFSIDES
144Bone lesionOFFSIDES
145Brain Diseases29458080CTD
146BruxismOFFSIDES
147Bunion operationOFFSIDES
148Burning sensationOFFSIDES
149Candidiasis of vaginaOFFSIDES
150Cardiac FlutterOFFSIDES
151Cardiac HypertrophyOFFSIDES
152Cardiac TamponadeOFFSIDES
153Cardiac function disturbance postoperativeOFFSIDES
154Cardiomegaly

View details

3024615
6099802
6723573
7494538
 		CTD
155Cataract operationOFFSIDES
156Catheter placementOFFSIDES
157Catheter related complicationOFFSIDES
158Central line infectionOFFSIDES
159Chemical and Drug Induced Liver Injury7377592
7503757
12516873		CTD
160Choking sensationOFFSIDES
161ChokingOFFSIDES
162ChromaturiaOFFSIDES
163Clostridium difficile colitisOFFSIDES
164Cognition Disorders9230642CTD
165Cold sweatOFFSIDES
166Color blindnessOFFSIDES
167Completed SuicideOFFSIDES
168ConfabulationOFFSIDES
169Congenital heart diseaseOFFSIDES
170CryingOFFSIDES
171DebridementOFFSIDES
172Dental FistulaOFFSIDES
173Dental abscessOFFSIDES
174Depressed moodOFFSIDES
175Depressive disorder3680608
8298824		CTD
176Device FailureOFFSIDES
177Device related infectionOFFSIDES
178DiabetesOFFSIDES
179DiarrheaOFFSIDES
180Dissociative disorderOFFSIDES
181DiverticulumOFFSIDES
182DrowsinessOFFSIDES
183Drug administration errorOFFSIDES
184Drug dispensing errorOFFSIDES
185Drug exposure during pregnancyOFFSIDES
186Drug level fluctuatingOFFSIDES
187Drug toxicityOFFSIDES
188Drug withdrawal headacheOFFSIDES
189DysgeusiaOFFSIDES
190DysmenorrheaOFFSIDES
191Dysthymic DisorderOFFSIDES
192DystoniaOFFSIDES
193DysuriaOFFSIDES
194Ejection Fraction DecreasedOFFSIDES
195Emotional distressOFFSIDES
196Endodontic procedureOFFSIDES
197EpistaxisOFFSIDES
198ErythemaOFFSIDES
199Essential TremorOFFSIDES
200Euphoric moodOFFSIDES
201Eustachian tube disorderOFFSIDES
202ExcoriationOFFSIDES
203Facial NeuralgiaOFFSIDES
204Failure of implantOFFSIDES
205Feeling ColdOFFSIDES
206Flat affectOFFSIDES
207Fluid overloadOFFSIDES
208Foreign body traumaOFFSIDES
209FormicationOFFSIDES
210FrustrationOFFSIDES
211GamblingOFFSIDES
212Gastric infectionOFFSIDES
213Gingival erythemaOFFSIDES
214Gingival graftOFFSIDES
215Glossopharyngeal NeuralgiaOFFSIDES
216GoiterOFFSIDES
217GranulocytosisOFFSIDES
218Granuloma7503757CTD
OFFSIDES
219HemiparesisOFFSIDES
220HepatitisOFFSIDES
221HordeolumOFFSIDES
222HyperkeratosisOFFSIDES
223HyperparathyroidismOFFSIDES
224Hypoaesthesia facialOFFSIDES
225Hypokalemic periodic paralysis19002009CTD
226HypophagiaOFFSIDES
227HyporeflexiaOFFSIDES
228HypotensionSIDER
229HysterectomyOFFSIDES
230Impaired gastric emptyingOFFSIDES
231Impaired self-careOFFSIDES
232Impaired work abilityOFFSIDES
233Implantable defibrillator malfunctionOFFSIDES
234Incision site cellulitisOFFSIDES
235Increased upper airway secretionOFFSIDES
236Injection site pruritusOFFSIDES
237Injury asphyxiationOFFSIDES
238Insulin-like growth factor increasedOFFSIDES
239Intention tremorOFFSIDES
240Intentional misuseOFFSIDES
241Intervertebral Disc DegenerationOFFSIDES
242Intervertebral disc disorderOFFSIDES
243Iodine allergyOFFSIDES
244IritisOFFSIDES
245Joint InstabilityOFFSIDES
246Joint injuryOFFSIDES
247Joint warmthOFFSIDES
248Keratitis siccaOFFSIDES
249Kidney FailureOFFSIDES
250Life expectancy shortenedOFFSIDES
251Limb Deformities, Congenital29458080CTD
252Lipid Metabolism Disorders6816881CTD
253Livedo ReticularisOFFSIDES
254Loose toothOFFSIDES
255Low turnover osteopathyOFFSIDES
256Lymphocyte count decreasedOFFSIDES
257MacroglossiaOFFSIDES
258MalabsorptionOFFSIDES
259Mastication disorderOFFSIDES
260Maxillofacial Abnormalities29458080CTD
261Mental impairmentOFFSIDES
262MetamorphopsiaOFFSIDES
263MetaplasiaOFFSIDES
264Metastatic painOFFSIDES
265Mononucleosis syndromeOFFSIDES
266Mouth BreathingOFFSIDES
267Multiple MyelomaOFFSIDES
268Multiple SclerosisOFFSIDES
269Multiple drug overdose intentionalOFFSIDES
270Muscle WeaknessOFFSIDES
271Musculoskeletal discomfortOFFSIDES
272Necrosis7377592
7503757
12516873		CTD
273Nephrogenic Diabetes InsipidusOFFSIDES
274Nervous tensionOFFSIDES
275Nodule on extremityOFFSIDES
276NystagmusOFFSIDES
277Occupational Diseases23084307CTD
278Ocular discomfortOFFSIDES
279Ocular icterusOFFSIDES
280OnychoclasisOFFSIDES
281Optic AtrophyOFFSIDES
282Optic NeuritisOFFSIDES
283Oral Cavity FistulaOFFSIDES
284Oral mucosa atrophyOFFSIDES
285Oropharyngeal painOFFSIDES
286OsteolysisOFFSIDES
287OsteomyelitisOFFSIDES
288OsteotomyOFFSIDES
289Ovarian InfectionOFFSIDES
290Paranasal sinus hypersecretionOFFSIDES
291ParanoiaOFFSIDES
292PericarditisOFFSIDES
293PeriodontitisOFFSIDES
294PhimosisOFFSIDES
295PhlebitisSIDER
296Pigmentation Disorders29458080CTD
297PlasmacytomaOFFSIDES
298PlasmacytosisOFFSIDES
299PleurisyOFFSIDES
300Polycystic Kidney Diseases8724899CTD
301PolymenorrheaOFFSIDES
302PolyuriaOFFSIDES
303Portal vein pressure increasedOFFSIDES
304Postmenopausal bleedingOFFSIDES
305Prescribed overdoseOFFSIDES
306Procedural complicationOFFSIDES
307Propionibacterium infectionOFFSIDES
308PsoriasisOFFSIDES
309Pulmonary HypertensionOFFSIDES
310Pulmonary arterial hypertensionOFFSIDES
311Pulmonary necrosisOFFSIDES
312Purulent dischargeOFFSIDES
313Quality of life decreasedOFFSIDES
314Rectal dischargeOFFSIDES
315Retinal Artery OcclusionOFFSIDES
316SarcoidosisOFFSIDES
317ScotomaOFFSIDES
318Seizures1513203CTD
319Skin IndurationOFFSIDES
320Skin hypertrophyOFFSIDES
321Skin lacerationOFFSIDES
322Skin neoplasm excisionOFFSIDES
323Soft Tissue InfectionOFFSIDES
324Spinal column stenosisOFFSIDES
325Stem cell transplantOFFSIDES
326StressOFFSIDES
327Subcutaneous noduleOFFSIDES
328Synovial CystOFFSIDES
329Systolic hypertensionOFFSIDES
330TachycardiaSIDER
331Tardive DyskinesiaOFFSIDES
332TendinitisOFFSIDES
333Thalamic infarctionOFFSIDES
334Therapeutic response unexpectedOFFSIDES
335Toe operationOFFSIDES
336Tooth ExtractionOFFSIDES
337Tooth InfectionOFFSIDES
338Tooth LossOFFSIDES
339Trisomy 21OFFSIDES
340Tubo-ovarian abscessOFFSIDES
341Unevaluable eventOFFSIDES
342Unresponsive to verbal stimuliOFFSIDES
343Uterine PolypOFFSIDES
344VIIth nerve paralysisOFFSIDES
345Vestibular Diseases29458080CTD
346Vestibular NeuronitisOFFSIDES
347VestibulitisOFFSIDES
348Viral labyrinthitisOFFSIDES
349Viral sinusitisOFFSIDES
350Vulvovaginal discomfortOFFSIDES
351Weight GainOFFSIDES
352Withdrawal bleeding irregularOFFSIDES
353Wound DebridementOFFSIDES
354Wound InfectionOFFSIDES
355Wound dehiscenceOFFSIDES
356Wound infection staphylococcalOFFSIDES
357effusionOFFSIDES
358fibromaOFFSIDES
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