MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Piperacillin, Tazobactam Drug Combination

(TUPFOYXHAYOHIB-YCAIQWGJSA-M)

Structure

SMILES: OC(=O)[C@@H]1N2C(=O)C[C@H]2S(=O)(=O)[C@@]1(C)Cn1ccnn1.CCN1CCN(C(=O)C1=O)C(=O)N[C@@H](C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)[O-])(C)C)c1ccccc1.[Na+]
Molecular Formula:: C33H38N9NaO12S2
Molecular Weight:: 839.828
Log P:: -1.4840
Hydrogen Bond Acceptor:: 22
Hydrogen Bond Donor:: 3
TPSA:: 315.4
CAS Number(s):: 157044-21-8

Synonym(s)

Piperacillin, Tazobactam Drug Combination

Piperacillin - Tazobactam

Piperacillin-Tazobactam Combination Product

Pipercillin Sodium - Tazobactam Sodium

Pipercillin Sodium, Tazobactam Sodium Drug Combination

Tazocel

Tazocillin

Tazocin

Zosyn

10.

Piperacillin Tazobactam

11.

Piperacillin Tazobactam Combination Product

12.

Pipercillin Sodium Tazobactam Sodium

13.

Tazobactam, Piperacillin -

External Link(s)

MeSH	D000077725
PubChem Compound	23695841

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Hypersensitivity	FAERS: 16 Canada Vigilance: 1		Canada Vigilance US FAERS
2	Erythema	FAERS: 12 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
3	Tachycardia	FAERS: 12		US FAERS
4	Cyanosis	FAERS: 9		US FAERS
5	Hypotension	FAERS: 9		US FAERS
6	Anaphylactic shock	FAERS: 8 Canada Vigilance: 1		Canada Vigilance US FAERS
7	Chest discomfort	FAERS: 8		US FAERS
8	Chills	FAERS: 8		US FAERS
9	Drug ineffective	FAERS: 7		US FAERS
10	Angioedema	FAERS: 6		US FAERS
11	Flushing	FAERS: 6		US FAERS
12	Pruritus	FAERS: 6 Canada Vigilance: 1		Canada Vigilance US FAERS
13	Sepsis	FAERS: 6 Canada Vigilance: 1		Canada Vigilance US FAERS
14	Vomiting	FAERS: 6 Canada Vigilance: 1		Canada Vigilance US FAERS
15	White blood cell count decreased	FAERS: 6		US FAERS
16	Bronchospasm	FAERS: 5		US FAERS
17	Cardiac Arrest	FAERS: 5		US FAERS
18	Abdominal Pain	FAERS: 4 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
19	Necrosis	FAERS: 4		US FAERS
20	Rash erythematous	FAERS: 4		US FAERS
21	Temperature intolerance	FAERS: 4		OFFSIDES US FAERS
22	Bradycardia	FAERS: 3		OFFSIDES US FAERS
23	Delirium	FAERS: 3		US FAERS
24	Documented hypersensitivity to administered product	FAERS: 3		US FAERS
25	Hyperpyrexia	FAERS: 3		US FAERS
26	Malaise	FAERS: 3		US FAERS
27	Nausea	FAERS: 3		OFFSIDES US FAERS
28	Product use issue	FAERS: 3		US FAERS
29	Respiratory arrest	FAERS: 3		US FAERS
30	Septic Shock	FAERS: 3		OFFSIDES US FAERS
31	Thrombocytopenia	FAERS: 3 Canada Vigilance: 2	16622157	CTD Canada Vigilance US FAERS
32	Unresponsive to stimuli	FAERS: 3		OFFSIDES US FAERS
33	Urinary Incontinence	FAERS: 3		US FAERS
34	Urticaria	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
35	Accidental exposure	FAERS: 2		US FAERS
36	Acute myocardial infarction	FAERS: 2		OFFSIDES US FAERS
37	Alanine Aminotransferase Increased	FAERS: 2		OFFSIDES US FAERS
38	Alanine aminotransferase abnormal	FAERS: 2		OFFSIDES US FAERS
39	Ankle Fracture	FAERS: 2		OFFSIDES US FAERS
40	Aspartate aminotransferase abnormal	FAERS: 2		OFFSIDES US FAERS
41	Asthma	FAERS: 2		US FAERS
42	Blood lactate dehydrogenase abnormal	FAERS: 2		OFFSIDES US FAERS
43	Cholestasis	FAERS: 2		US FAERS
44	Clostridium difficile infection	FAERS: 2		US FAERS
45	Dizziness	FAERS: 2		US FAERS
46	Enlarged uvula	FAERS: 2		US FAERS
47	Epilepsy	FAERS: 2		US FAERS
48	Febrile Neutropenia	FAERS: 2		OFFSIDES US FAERS
49	Gamma-glutamyltransferase abnormal	FAERS: 2		OFFSIDES US FAERS
50	Headache	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
51	Hepatotoxicity	FAERS: 2		OFFSIDES US FAERS
52	Laryngospasm	FAERS: 2		US FAERS
53	Pallor	FAERS: 2		US FAERS
54	Palpitations	FAERS: 2		US FAERS
55	Respiratory Failure	FAERS: 2		OFFSIDES US FAERS
56	Abdominal discomfort	FAERS: 1		US FAERS
57	Accidental overdose	FAERS: 1		US FAERS
58	Agitation	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
59	Agranulocytosis	FAERS: 1		US FAERS
60	Anuria	FAERS: 1		US FAERS
61	Arthralgia	FAERS: 1	9017778	CTD US FAERS
62	Aspartate Aminotransferase Increased	FAERS: 1		US FAERS
63	Asthenia	FAERS: 1		OFFSIDES US FAERS
64	Autoimmune thrombocytopenia	FAERS: 1		US FAERS
65	Back Pain	FAERS: 1		US FAERS
66	Base excess decreased	FAERS: 1		US FAERS
67	Blood alkaline phosphatase increased	FAERS: 1		OFFSIDES US FAERS
68	Blood chloride decreased	FAERS: 1		OFFSIDES US FAERS
69	Blood pH decreased	FAERS: 1		US FAERS
70	Blood pressure fluctuation	FAERS: 1		OFFSIDES US FAERS
71	Blood pressure immeasurable	FAERS: 1		US FAERS
72	Blood sodium decreased	FAERS: 1		US FAERS
73	Budd-Chiari Syndrome	FAERS: 1		US FAERS
74	Burning sensation	FAERS: 1		US FAERS
75	Central line infection	FAERS: 1		OFFSIDES US FAERS
76	Chest Pain	FAERS: 1		US FAERS
77	Choking sensation	FAERS: 1		OFFSIDES US FAERS
78	Choking	FAERS: 1		US FAERS
79	Clostridium test positive	FAERS: 1		US FAERS
80	Cold sweat	FAERS: 1		US FAERS
81	Concomitant disease progression	FAERS: 1		OFFSIDES US FAERS
82	Contraindicated product prescribed	FAERS: 1		US FAERS
83	Dermatitis	FAERS: 1		US FAERS
84	Diffuse panbronchiolitis	FAERS: 1		US FAERS
85	Discomfort	FAERS: 1		US FAERS
86	Disseminated Intravascular Coagulation	FAERS: 1		OFFSIDES US FAERS
87	Diverticulitis	FAERS: 1		US FAERS
88	Documented hypersensitivity to administered drug	FAERS: 1		OFFSIDES US FAERS
89	Drug prescribing error	FAERS: 1		US FAERS
90	Dysbacteriosis	FAERS: 1		US FAERS
91	Eosinophilic myocarditis	FAERS: 1		OFFSIDES US FAERS
92	Erythropenia	FAERS: 1		US FAERS
93	Extravasation	FAERS: 1		US FAERS
94	Eye pain	FAERS: 1		US FAERS
95	Facial Pain	FAERS: 1		US FAERS
96	Feeling Cold	FAERS: 1		US FAERS
97	Feeling abnormal	FAERS: 1		US FAERS
98	Infusion site pain	FAERS: 1		OFFSIDES US FAERS
99	Intercepted medication error	FAERS: 1		US FAERS
100	Labile blood pressure	FAERS: 1		OFFSIDES US FAERS
101	Leukopenia	FAERS: 1		US FAERS
102	Limb discomfort	FAERS: 1		US FAERS
103	Musculoskeletal discomfort	FAERS: 1		US FAERS
104	Myocardial Infarction	FAERS: 1		US FAERS
105	Myocarditis	FAERS: 1		US FAERS
106	Occult blood positive	FAERS: 1		US FAERS
107	Occupational exposure to product	FAERS: 1		US FAERS
108	Opisthotonus	FAERS: 1		US FAERS
109	Overdose	FAERS: 1		US FAERS
110	PCO2 increased	FAERS: 1		US FAERS
111	PO2 decreased	FAERS: 1		US FAERS
112	Palmar erythema	FAERS: 1		US FAERS
113	Pneumonitis	FAERS: 1		US FAERS
114	Purpura	FAERS: 1		US FAERS
115	Rales	FAERS: 1		US FAERS
116	Respiratory distress	FAERS: 1		US FAERS
117	Rhabdomyolysis	FAERS: 1		US FAERS
118	Rhonchi	FAERS: 1		US FAERS
119	Shock	FAERS: 1		US FAERS
120	Skin lesion	FAERS: 1		US FAERS
121	Skin reaction	FAERS: 1		US FAERS
122	Swelling	FAERS: 1		US FAERS
123	Toxic Epidermal Necrolysis	FAERS: 1		US FAERS
124	Transaminases increased	FAERS: 1		US FAERS
125	Transfusion Reaction	FAERS: 1		US FAERS
126	Typhoid Fever	FAERS: 1		US FAERS
127	Urinary Retention	FAERS: 1		US FAERS
128	Vasculitis	FAERS: 1		US FAERS
129	Wheezing	FAERS: 1		US FAERS
130	nervous system disorder	FAERS: 1		US FAERS
131	Abdominal Abscess			OFFSIDES
132	Abdominal Infection			OFFSIDES
133	Abdominal sepsis			OFFSIDES
134	Abscess			OFFSIDES
135	Accelerated Idioventricular Rhythm			OFFSIDES
136	Acid fast bacilli infection			OFFSIDES
137	Acid reflux			OFFSIDES
138	Acidosis			OFFSIDES
139	Actinic keratosis			OFFSIDES
140	Actinomycosis		15155214	CTD
141	Acute graft versus host disease in intestine			OFFSIDES
142	Acute graft versus host disease in liver			OFFSIDES
143	Acute kidney injury		9017778	CTD
144	Acute promyelocytic leukaemia differentiation syndrome			OFFSIDES
145	Acute respiratory failure			OFFSIDES
146	Adnexitis			OFFSIDES
147	Adrenal atrophy			OFFSIDES
148	Adrenal mass			OFFSIDES
149	Alcohol withdrawal syndrome			OFFSIDES
150	Allergy to arthropod sting			OFFSIDES
151	Alveolitis			OFFSIDES
152	Alveoloplasty			OFFSIDES
153	Ammonia increased			OFFSIDES
154	Anastomotic stenosis			OFFSIDES
155	Anemia, Hemolytic		17381629 20101875	CTD
156	Animal bite			OFFSIDES
157	Animal scratch			OFFSIDES
158	Anti-erythrocyte antibody positive			OFFSIDES
159	Anti-platelet antibody positive			OFFSIDES
160	Antidepressant drug clearance decreased			OFFSIDES
161	Antiphospholipid antibodies positive			OFFSIDES
162	Antithrombin III decreased			OFFSIDES
163	Anxiety			OFFSIDES
164	Aortic Injury			OFFSIDES
165	Aphagia			OFFSIDES
166	Appendicitis			OFFSIDES
167	Arterial bypass operation			OFFSIDES
168	Arteriosclerosis			OFFSIDES
169	Arteriovenous fistula			OFFSIDES
170	Arthropod bite			OFFSIDES
171	Ascites infection			OFFSIDES
172	Ascites			OFFSIDES
173	Aspergillosis			OFFSIDES
174	Aspiration Pneumonia			OFFSIDES
175	Atelectasis			OFFSIDES
176	Atrial tachycardia			OFFSIDES
177	Autoimmune hepatitis			OFFSIDES
178	B-cell lymphoma recurrent			OFFSIDES
179	Bacillus infection			OFFSIDES
180	Bacteria blood identified			OFFSIDES
181	Bacteria stool identified			OFFSIDES
182	Bacteria urine identified			OFFSIDES
183	Bacteria urine no organism observed			OFFSIDES
184	Bacteria wound identified			OFFSIDES
185	Bacterial test positive			OFFSIDES
186	Band neutrophil percentage decreased			OFFSIDES
187	Bicytopenia			OFFSIDES
188	Bile duct necrosis			OFFSIDES
189	Bilirubin conjugated increased			OFFSIDES
190	Bladder prolapse			OFFSIDES
191	Bladder spasm			OFFSIDES
192	Blepharitis			OFFSIDES
193	Blepharoptosis			OFFSIDES
194	Blood Glucose			OFFSIDES
195	Blood albumin decreased			OFFSIDES
196	Blood bicarbonate			OFFSIDES
197	Blood chloride increased			OFFSIDES
198	Blood creatine increased	Canada Vigilance: 1		Canada Vigilance
199	Blood creatine phosphokinase			OFFSIDES
200	Blood creatinine increased			OFFSIDES
201	Blood electrolytes abnormal			OFFSIDES
202	Blood fibrinogen increased			OFFSIDES
203	Blood glucose decreased			OFFSIDES
204	Blood glucose fluctuation			OFFSIDES
205	Blood lactate dehydrogenase increased			OFFSIDES
206	Blood magnesium decreased			OFFSIDES
207	Blood osmolarity increased			OFFSIDES
208	Blood pH increased			OFFSIDES
209	Blood phosphorus decreased			OFFSIDES
210	Blood phosphorus increased			OFFSIDES
211	Blood potassium decreased			OFFSIDES
212	Blood potassium increased			OFFSIDES
213	Blood sodium increased	Canada Vigilance: 1		Canada Vigilance OFFSIDES
214	Blood urea increased	Canada Vigilance: 1		Canada Vigilance OFFSIDES
215	Body Temperature			OFFSIDES
216	Bone fistula			OFFSIDES
217	Bone lesion			OFFSIDES
218	Bone pain			OFFSIDES
219	Bordetella Infections		9755831	CTD
220	Brain Abscess			OFFSIDES
221	Brain natriuretic peptide abnormal			OFFSIDES
222	Breast tenderness			OFFSIDES
223	Breech Presentation			OFFSIDES
224	Bronchopneumonia			OFFSIDES
225	Bronchoscopy abnormal			OFFSIDES
226	Bulbar palsy			OFFSIDES
227	C-reactive protein abnormal			OFFSIDES
228	CYTOMEGALOVIRUS ANTIGEN			OFFSIDES
229	Candiduria			OFFSIDES
230	Carbon dioxide abnormal			OFFSIDES
231	Cardiac Tamponade			OFFSIDES
232	Cardiac enzymes increased			OFFSIDES
233	Carotid bruit			OFFSIDES
234	Catheter related infection			OFFSIDES
235	Catheter sepsis			OFFSIDES
236	Catheter site cellulitis			OFFSIDES
237	Catheter site infection			OFFSIDES
238	Catheter site necrosis			OFFSIDES
239	Catheter site pain			OFFSIDES
240	Cavernous Sinus Thrombosis			OFFSIDES
241	Cellulitis			OFFSIDES
242	Central Nervous System Infection			OFFSIDES
243	Cerebral atrophy			OFFSIDES
244	Cerebral dysgenesis			OFFSIDES
245	Cholangiolitis			OFFSIDES
246	Cholecystitis			OFFSIDES
247	Chromatopsia			OFFSIDES
248	Chromaturia	Canada Vigilance: 1		Canada Vigilance
249	Chronic Obstructive Airway Disease			OFFSIDES
250	Chronic respiratory failure			OFFSIDES
251	Chronic sinusitis			OFFSIDES
252	Circumstance or information capable of leading to medication error			OFFSIDES
253	Clostridium Infections		15155214	CTD
254	Clostridium difficile colitis			OFFSIDES
255	Clostridium difficile toxin test positive			OFFSIDES
256	Colitis			OFFSIDES
257	Colon adenoma			OFFSIDES
258	Colonic fistula			OFFSIDES
259	Complications of transplant surgery			OFFSIDES
260	Compression fracture			OFFSIDES
261	Concomitant disease aggravated			OFFSIDES
262	Confusion		15102992 17496739 19499182	CTD
263	Congenital tricuspid valve incompetence			OFFSIDES
264	Cor pulmonale			OFFSIDES
265	Coronary artery embolism			OFFSIDES
266	Corynebacterium Infections		15155214	CTD
267	Creatinine renal clearance decreased			OFFSIDES
268	Culture positive			OFFSIDES
269	Culture wound positive			OFFSIDES
270	Cutaneous Candidiasis			OFFSIDES
271	Cytomegalovirus antibody positive			OFFSIDES
272	Cytomegalovirus test positive			OFFSIDES
273	Deafness			OFFSIDES
274	Debridement			OFFSIDES
275	Demyelination			OFFSIDES
276	Dental caries			OFFSIDES
277	Dental prosthesis user			OFFSIDES
278	Dentofacial anomaly			OFFSIDES
279	Denture wearer			OFFSIDES
280	Depressed Level of Consciousness			OFFSIDES
281	Device Failure			OFFSIDES
282	Device breakage			OFFSIDES
283	Device interaction			OFFSIDES
284	Device related infection			OFFSIDES
285	Diarrhea			OFFSIDES
286	Diffuse alveolar damage			OFFSIDES
287	Dilatation intrahepatic duct acquired			OFFSIDES
288	Diverticular fistula			OFFSIDES
289	Diverticulum			OFFSIDES
290	Duodenal ulcer perforation			OFFSIDES
291	Duodenitis			OFFSIDES
292	Duodenogastric Reflux			OFFSIDES
293	Eating disorder symptom			OFFSIDES
294	Economic problem			OFFSIDES
295	Ejection Fraction Decreased			OFFSIDES
296	Electrocardiogram QRS complex			OFFSIDES
297	Electrocardiogram ST segment abnormal			OFFSIDES
298	Electrocardiogram ST-T change			OFFSIDES
299	Electrocardiogram T wave peaked			OFFSIDES
300	Electrocardiogram change			OFFSIDES
301	Electrocardiogram poor R-wave progression			OFFSIDES
302	Electromechanical dissociation			OFFSIDES
303	Embolic stroke			OFFSIDES
304	Emotional disorder			OFFSIDES
305	Emotional distress			OFFSIDES
306	Endocarditis			OFFSIDES
307	Endodontic procedure			OFFSIDES
308	Endometriosis			OFFSIDES
309	Endoscopic Retrograde Cholangiopancreatography			OFFSIDES
310	Enterococcal infection			OFFSIDES
311	Eosinophil percentage increased			OFFSIDES
312	Epididymitis			OFFSIDES
313	Epistaxis			OFFSIDES
314	Erectile dysfunction			OFFSIDES
315	Escherichia coli Infections		19499182	CTD
316	Escherichia infection			OFFSIDES
317	Escherichia sepsis			OFFSIDES
318	Esophageal Stenosis			OFFSIDES
319	Ethmoid sinus surgery			OFFSIDES
320	Exanthema		9017778	CTD
321	Exfoliative rash			OFFSIDES
322	Exophthalmos			OFFSIDES
323	Extremity contracture			OFFSIDES
324	Failure to anastomose			OFFSIDES
325	Fatty Liver			OFFSIDES
326	Feeding tube complication			OFFSIDES
327	Femoral artery occlusion			OFFSIDES
328	Fever		9017778 16622157	CTD
329	Flank Pain			OFFSIDES
330	Flat affect			OFFSIDES
331	Flatulence			OFFSIDES
332	Fluid overload			OFFSIDES
333	Foaming at mouth			OFFSIDES
334	Focal glomerulosclerosis			OFFSIDES
335	Fracture treatment			OFFSIDES
336	Galactorrhea			OFFSIDES
337	Gamma-Glutamyltransferase Increased			OFFSIDES
338	Gammopathy			OFFSIDES
339	Gangrene			OFFSIDES
340	Gastrointestinal arteriovenous malformation			OFFSIDES
341	Gastrointestinal perforation			OFFSIDES
342	Gastrointestinal stoma complication			OFFSIDES
343	Gastrointestinal ulcer			OFFSIDES
344	General physical health deterioration			OFFSIDES
345	Goiter			OFFSIDES
346	Granulocytosis			OFFSIDES
347	Haemophilus Infections		9755831	CTD
348	Hallucinations		15102992 19499182	CTD
349	Heparin-induced thrombocytopenia			OFFSIDES
350	Hepatic artery occlusion			OFFSIDES
351	Hepatic artery thrombosis			OFFSIDES
352	Hepatic candidiasis			OFFSIDES
353	Hepatic congestion			OFFSIDES
354	Hepatic vein occlusion			OFFSIDES
355	Hepatitis A			OFFSIDES
356	Hepatitis B positive			OFFSIDES
357	Histiocytosis haematophagic			OFFSIDES
358	Histoplasmosis			OFFSIDES
359	Hormone level abnormal			OFFSIDES
360	Hydrocephalus			OFFSIDES
361	Hypercapnia			OFFSIDES
362	Hyperosmolar state			OFFSIDES
363	Hypokalemia		20642978	CTD
364	Hypophagia			OFFSIDES
365	Hypoxia			OFFSIDES
366	Immune reconstitution syndrome			OFFSIDES
367	Immunosuppressant drug level			OFFSIDES
368	Incision site pain			OFFSIDES
369	Incontinence			OFFSIDES
370	Infection			OFFSIDES
371	Infusion Site Extravasation			OFFSIDES
372	Injection site inflammation			OFFSIDES
373	Injection site pustule			OFFSIDES
374	Inspiratory capacity decreased			OFFSIDES
375	Intermittent Claudication			OFFSIDES
376	Intervertebral Disc Degeneration			OFFSIDES
377	Intervertebral disc disorder			OFFSIDES
378	Intestinal Obstruction			OFFSIDES
379	Joint sprain			OFFSIDES
380	Kidney Failure			OFFSIDES
381	Klebsiella sepsis			OFFSIDES
382	Laceration			OFFSIDES
383	Lactobacillus infection			OFFSIDES
384	Lethargy			OFFSIDES
385	Leucine aminopeptidase increased			OFFSIDES
386	Leukopenia neonatal			OFFSIDES
387	Leukoplakia			OFFSIDES
388	Lichen Planus			OFFSIDES
389	Life expectancy shortened			OFFSIDES
390	Lipase			OFFSIDES
391	Livedo Reticularis			OFFSIDES
392	Liver Abscess			OFFSIDES
393	Liver transplant rejection			OFFSIDES
394	Lumbar radiculopathy			OFFSIDES
395	Lung Abscess			OFFSIDES
396	Lung consolidation			OFFSIDES
397	Lung infection pseudomonal			OFFSIDES
398	Lymphedema			OFFSIDES
399	Malabsorption			OFFSIDES
400	Mandibular prosthesis user			OFFSIDES
401	Mastoiditis			OFFSIDES
402	Maxillofacial operation			OFFSIDES
403	Mechanical ventilation			OFFSIDES
404	Megacolon			OFFSIDES
405	Meningioma			OFFSIDES
406	Mental status changes			OFFSIDES
407	Metabolic acidosis			OFFSIDES
408	Metastases to mouth			OFFSIDES
409	Metastatic Neoplasm			OFFSIDES
410	Metastatic pain			OFFSIDES
411	Micrographic skin surgery			OFFSIDES
412	Mononeuritis			OFFSIDES
413	Multi-organ disorder			OFFSIDES
414	Muscle Weakness			OFFSIDES
415	Musculoskeletal chest pain			OFFSIDES
416	Mycosis Fungoides			OFFSIDES
417	Nephritis allergic			OFFSIDES
418	Nephritis, Interstitial		9017778 16649401	CTD
419	Nephrogenic Diabetes Insipidus	Canada Vigilance: 1		Canada Vigilance OFFSIDES
420	Nephrolithiasis			OFFSIDES
421	Neuralgic Amyotrophy			OFFSIDES
422	Neurogenic Bowel			OFFSIDES
423	Neurological decompensation			OFFSIDES
424	Neutropenia	Canada Vigilance: 4	16622157	CTD Canada Vigilance
425	Neutropenic sepsis			OFFSIDES
426	Nodule			OFFSIDES
427	Nonspecific reaction			OFFSIDES
428	Ocular icterus	Canada Vigilance: 1		Canada Vigilance OFFSIDES
429	Oliguria			OFFSIDES
430	Open wound			OFFSIDES
431	Ophthalmoplegia			OFFSIDES
432	Oroantral Fistula			OFFSIDES
433	Orthopnea			OFFSIDES
434	Osteolysis			OFFSIDES
435	Osteomyelitis			OFFSIDES
436	Osteopenia			OFFSIDES
437	Osteoporosis			OFFSIDES
438	Oxygen consumption increased			OFFSIDES
439	Pain		9017778	CTD OFFSIDES
440	Pancreatic Pseudocyst			OFFSIDES
441	Pancreatitis			OFFSIDES
442	Pancytopenia		8982034	CTD
443	Panophthalmitis			OFFSIDES
444	Paracentesis			OFFSIDES
445	Paresthesia		16622157	CTD
446	Parvovirus B19 serology positive			OFFSIDES
447	Patellofemoral Pain Syndrome			OFFSIDES
448	Pelvic abscess			OFFSIDES
449	Pelvic fluid collection			OFFSIDES
450	Pericardial Cyst			OFFSIDES
451	Pericardial effusion			OFFSIDES
452	Pericarditis			OFFSIDES
453	Peritonitis			OFFSIDES
454	Plasmacytoma			OFFSIDES
455	Plasmapheresis			OFFSIDES
456	Pleurisy			OFFSIDES
457	Pneumothorax			OFFSIDES
458	Poikilocytosis			OFFSIDES
459	Polyuria			OFFSIDES
460	Poor dental condition			OFFSIDES
461	Poor personal hygiene			OFFSIDES
462	Post procedural complication			OFFSIDES
463	Post procedural infection			OFFSIDES
464	Postoperative abscess			OFFSIDES
465	Postoperative renal failure			OFFSIDES
466	Posturing			OFFSIDES
467	Proctitis			OFFSIDES
468	Prolapse repair			OFFSIDES
469	Propofol Infusion Syndrome			OFFSIDES
470	Protein total increased			OFFSIDES
471	Psychomotor skills impaired			OFFSIDES
472	Pulmonary Eosinophilia			OFFSIDES
473	Pulmonary congestion			OFFSIDES
474	Rectal Prolapse			OFFSIDES
475	Red man syndrome			OFFSIDES
476	Refusal of treatment by relative			OFFSIDES
477	Renal tubular acidosis			OFFSIDES
478	Renal tubular necrosis			OFFSIDES
479	Residual urine			OFFSIDES
480	Respiratory tract infection fungal			OFFSIDES
481	Reticulocyte count increased			OFFSIDES
482	Retroperitoneal abscess			OFFSIDES
483	Septic embolus			OFFSIDES
484	Sequestrectomy			OFFSIDES
485	Sinus antrostomy			OFFSIDES
486	Sinus headache			OFFSIDES
487	Sinusitis			OFFSIDES
488	Skin laceration			OFFSIDES
489	Sleep Initiation and Maintenance Disorders		15102992	CTD
490	Sphincter of Oddi Dysfunction			OFFSIDES
491	Spinal column stenosis			OFFSIDES
492	Splenic Infarction			OFFSIDES
493	Splenic candidiasis			OFFSIDES
494	Splenic cyst			OFFSIDES
495	Spondylolisthesis			OFFSIDES
496	Sputum culture positive			OFFSIDES
497	Staphylococcal Infections		9755831	CTD
498	Staring			OFFSIDES
499	Stem cell transplant			OFFSIDES
500	Stenotrophomonas infection			OFFSIDES
501	Streptococcal Infections		9755831	CTD
502	Subacute endocarditis			OFFSIDES
503	Subcutaneous nodule			OFFSIDES
504	Synovial Cyst			OFFSIDES
505	Synovitis			OFFSIDES
506	Therapy cessation			OFFSIDES
507	Thoracic cavity drainage			OFFSIDES
508	Throat cancer			OFFSIDES
509	Thrombophlebitis			OFFSIDES
510	Tooth Extraction			OFFSIDES
511	Tooth Infection			OFFSIDES
512	Tooth Loss			OFFSIDES
513	Tooth repair			OFFSIDES
514	Tracheal Stenosis			OFFSIDES
515	Tremor		17496739	CTD
516	Trichosporon infection			OFFSIDES
517	Urinary tract infection pseudomonal			OFFSIDES
518	Urination Disorders		9017778	CTD
519	Uterovaginal prolapse			OFFSIDES
520	Vaginal cellulitis			OFFSIDES
521	Vaginal mycosis			OFFSIDES
522	Vascular calcification			OFFSIDES
523	Venoocclusive disease			OFFSIDES
524	Ventricular Fibrillation			OFFSIDES
525	Wound Infection			OFFSIDES
526	Wound decomposition			OFFSIDES
527	Wound infection staphylococcal			OFFSIDES
528	colonoscopy			OFFSIDES
529	jaundice	Canada Vigilance: 1		Canada Vigilance
530	kyphosis			OFFSIDES
531	treatment failure			OFFSIDES

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