MetaADEDB 2.0 @ LMMD
alfacalcidol
(OFHCOWSQAMBJIW-AVJTYSNKSA-N)
Structure
SMILES
CC(CCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CCC/C/2=C\C=C/1\C[C@@H](O)C[C@@H](C1=C)O)C)C
Type(s)
Approved; Nutraceutical
ATC code(s)
A11CC03; M05BB06
Molecular Formula:
C27H44O2
Molecular Weight:
400.637
Log P:
6.5898
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
2
TPSA:
40.46
CAS Number(s):
41294-56-8; 65445-14-9
Synonym(s)
1.
alfacalcidol
2.
1 alpha-hydroxycholecalciferol
3.
1 alpha-hydroxyvitamin D3
4.
1-alpha-oxycholecalciferol
5.
1-hydroxycholecalciferol
6.
1-hydroxycholecalciferol, (1alpha,3alpha-(5Z,7E))-isomer
7.
1-hydroxycholecalciferol, (1beta)-(5Z)-isomer
8.
1-hydroxycholecalciferol, (1beta,3beta-(5E,7E))-isomer
9.
1-hydroxycholecalciferol, aluminum salt
10.
1alpha-OHD3
11.
AlfaD
12.
Bondiol
13.
Eenalfadrie
14.
EinsAlpha
15.
Etalpha
16.
Oksidevit
17.
One-Alpha
18.
Un-Alfa
19.
alphacalcidol
External Link(s)
MeSHC008088
PubChem Compound5282181
ChEBI94779
31186
CHEMBLCHEMBL1601669
DrugBankDB01436
DrugCentral130
KEGGdr:D01518
ZINC12484965
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal AbscessOFFSIDES
2Abdominal massOFFSIDES
3Acetonaemic vomitingOFFSIDES
4Acute kidney injury20453404CTD
5AdenitisOFFSIDES
6Adenocarcinoma17893519CTD
7Adrenal atrophyOFFSIDES
8Alanine Aminotransferase IncreasedOFFSIDES
9Albumin globulin ratio decreasedOFFSIDES
10Alkalosis20453404CTD
11Altered state of consciousnessOFFSIDES
12AminoaciduriaOFFSIDES
13AmyloidosisOFFSIDES
14AnorexiaOFFSIDES
15Anti-erythropoietin antibody positiveOFFSIDES
16Anti-insulin antibody positiveOFFSIDES
17Antiphospholipid SyndromeOFFSIDES
18AnuriaOFFSIDES
19ApathyOFFSIDES
20AppendicitisOFFSIDES
21Arteriosclerotic retinopathyOFFSIDES
22Arteriovenous graft thrombosisOFFSIDES
23AscitesOFFSIDES
24Atlantoaxial instabilityOFFSIDES
25Atrioventricular BlockOFFSIDES
26Atrophy of tongue papillaeOFFSIDES
27AuraOFFSIDES
28Autoimmune hepatitisOFFSIDES
29B-cell lymphoma stage IVOFFSIDES
30Bacterial conjunctivitisOFFSIDES
31Band neutrophil count increasedOFFSIDES
32Band neutrophil percentage decreasedOFFSIDES
33Band neutrophil percentage increasedOFFSIDES
34Beta 2 microglobulin urine increasedOFFSIDES
35Beta-N-acetyl-D-glucosaminidase increasedOFFSIDES
36Biliary dilatationOFFSIDES
37Blood albumin decreasedOFFSIDES
38Blood alkaline phosphatase increasedOFFSIDES
39Blood beta-D-glucan abnormalOFFSIDES
40Blood beta-D-glucan increasedOFFSIDES
41Blood chloride decreasedOFFSIDES
42Blood cholinesterase decreasedOFFSIDES
43Blood creatine phosphokinase decreasedOFFSIDES
44Blood creatine phosphokinase increasedOFFSIDES
45Blood creatinine decreasedOFFSIDES
46Blood creatinine increasedOFFSIDES
47Blood fibrinogen increasedOFFSIDES
48Blood immunoglobulin G increasedOFFSIDES
49Blood iron decreasedOFFSIDES
50Blood lactate dehydrogenase increasedOFFSIDES
51Blood osmolarity abnormalOFFSIDES
52Blood pH increasedOFFSIDES
53Blood parathyroid hormone decreasedOFFSIDES
54Blood parathyroid hormone increasedOFFSIDES
55Blood phosphorus increasedOFFSIDES
56Blood potassium decreasedOFFSIDES
57Blood potassium increasedOFFSIDES
58Blood pressure fluctuationOFFSIDES
59Blood product transfusion dependentOFFSIDES
60Blood sodiumOFFSIDES
61Blood urea increasedOFFSIDES
62Blood uric acidOFFSIDES
63Bone marrow depressionOFFSIDES
64BradycardiaOFFSIDES
65Brain AbscessOFFSIDES
66Brain stem syndromeOFFSIDES
67BronchiectasisOFFSIDES
68Bronchoalveolar LavageOFFSIDES
69Bulbar palsyOFFSIDES
70CYTOMEGALOVIRUS ANTIGENOFFSIDES
71Calcific deposits removalOFFSIDES
72CalcinosisCanada Vigilance: 1Canada Vigilance
73CalciphylaxisOFFSIDES
74Candida sepsisOFFSIDES
75Carcinoembryonic antigen increasedOFFSIDES
76Cardiac TamponadeOFFSIDES
77Cardioactive drug level above therapeuticOFFSIDES
78CataractOFFSIDES
79Catheter placementOFFSIDES
80Catheter related infectionOFFSIDES
81Catheter site related reactionOFFSIDES
82Cerebral disorderOFFSIDES
83Chemotherapeutic drug level increasedOFFSIDES
84ChokingOFFSIDES
85CholangiolitisOFFSIDES
86Cholestatic liver injuryOFFSIDES
87Chronic respiratory failureOFFSIDES
88Color blindnessOFFSIDES
89Colorectal Neoplasms17893519CTD
90Compression fractureOFFSIDES
91Concomitant disease aggravatedOFFSIDES
92Congenital pyelocaliectasisOFFSIDES
93ContractureOFFSIDES
94Corneal epithelium disorderOFFSIDES
95Creatinine renal clearance decreasedOFFSIDES
96Cytomegalovirus test positiveOFFSIDES
97Decreased immune responsivenessOFFSIDES
98Delusional disorder, persecutory typeOFFSIDES
99Depressed Level of ConsciousnessOFFSIDES
100DermatomyositisOFFSIDES
101Device interactionOFFSIDES
102Disseminated Intravascular CoagulationOFFSIDES
103Duodenal perforationOFFSIDES
104DyscalculiaOFFSIDES
105DyslaliaOFFSIDES
106EncephalitisOFFSIDES
107EndophthalmitisOFFSIDES
108Endotoxic shockOFFSIDES
109Engraftment syndromeOFFSIDES
110Enterococcal infectionOFFSIDES
111Enterocolitis bacterialOFFSIDES
112EnterocolitisOFFSIDES
113EpidermolysisOFFSIDES
114Epstein-Barr virus test positiveOFFSIDES
115Escherichia sepsisOFFSIDES
116Eyelid Function DisorderOFFSIDES
117Familial Hypophosphatemic Rickets18775977CTD
118Fanconi SyndromeOFFSIDES
119Focal glomerulosclerosisOFFSIDES
120Food PoisoningOFFSIDES
121Fungus serology test positiveOFFSIDES
122Gamma-Glutamyltransferase IncreasedOFFSIDES
123GangreneOFFSIDES
124Gastric mucosal lesionOFFSIDES
125Gastric ulcerOFFSIDES
126GastroenteritisOFFSIDES
127Gastrointestinal motility disorderOFFSIDES
128General physical conditionOFFSIDES
129General physical health deteriorationOFFSIDES
130GlobulinuriaOFFSIDES
131GlossitisOFFSIDES
132Graves Disease9322804CTD
133Heart-lung transplant rejectionOFFSIDES
134HemiplegiaOFFSIDES
135Hepatitis B DNA increasedOFFSIDES
136Hepatitis BOFFSIDES
137HepatoblastomaOFFSIDES
138HiccoughOFFSIDES
139Hilar lymphadenopathyOFFSIDES
140Histiocytosis haematophagicOFFSIDES
141HordeolumOFFSIDES
142HydropneumothoraxOFFSIDES
143Hypercalcemia

View details

CTD
144HypercapniaOFFSIDES
145HypercreatinaemiaOFFSIDES
146Hyperparathyroidism, Secondary8840326CTD
147HyperparathyroidismOFFSIDES
148HyperventilationOFFSIDES
149Hypocalcemia11701698CTD
150Hypoparathyroidism familial isolated20119591CTD
151Hypoparathyroidism2616424CTD
152HypophagiaOFFSIDES
153HypoxiaOFFSIDES
154HypozincaemiaOFFSIDES
155Ileal ulcerOFFSIDES
156Immunosuppressant drug levelOFFSIDES
157ImmunosuppressionOFFSIDES
158ImpetigoOFFSIDES
159IncoherentOFFSIDES
160Infected cystOFFSIDES
161Infection in an immunocompromised hostOFFSIDES
162Injury asphyxiationOFFSIDES
163Insulin autoimmune syndromeOFFSIDES
164Intestinal ObstructionOFFSIDES
165Intestinal adenocarcinomaOFFSIDES
166Intracardiac massOFFSIDES
167Intraocular lens dislocationOFFSIDES
168IntussusceptionOFFSIDES
169Iron OverloadOFFSIDES
170Laboratory test interferenceOFFSIDES
171Lack of spontaneous speechOFFSIDES
172Large intestine perforationOFFSIDES
173LegionellaOFFSIDES
174LeukoencephalopathyOFFSIDES
175Leukopenia neonatalOFFSIDES
176LeukoplakiaOFFSIDES
177Lichen PlanusOFFSIDES
178Lip erosionOFFSIDES
179LipogranulomaOFFSIDES
180Liver AbscessOFFSIDES
181Low Cardiac Output SyndromeOFFSIDES
182Lung AbscessOFFSIDES
183Lung InjuryOFFSIDES
184Lung cystOFFSIDES
185Lung infection pseudomonalOFFSIDES
186Lupus NephritisOFFSIDES
187LymphangiomaOFFSIDES
188LymphangitisOFFSIDES
189LymphoceleOFFSIDES
190Lymphocyte count decreasedOFFSIDES
191Lymphocyte percentage decreasedOFFSIDES
192Lymphocyte stimulation test positiveOFFSIDES
193Lymphoma, Follicular2996693CTD
194LymphomaOFFSIDES
195Malignant HypertensionOFFSIDES
196Malignant tumour excisionOFFSIDES
197Mammary Neoplasms, Experimental2563099CTD
198Megakaryocytes increasedOFFSIDES
199MelanosisOFFSIDES
200Mesangioproliferative glomerulonephritisOFFSIDES
201Metabolic acidosisOFFSIDES
202MoaningOFFSIDES
203Monocyte percentage decreasedOFFSIDES
204Monocyte percentage increasedOFFSIDES
205MonoplegiaOFFSIDES
206Multiple System AtrophyOFFSIDES
207Multiple sclerosis relapseOFFSIDES
208MyelitisOFFSIDES
209Myeloblast count increasedOFFSIDES
210MyringitisOFFSIDES
211NasopharyngitisOFFSIDES
212Nephrocalcinosis11701698CTD
213Nephrogenic Fibrosing DermopathyOFFSIDES
214Nephrotic SyndromeOFFSIDES
215Neuromyelitis OpticaOFFSIDES
216Obsessive thoughtsOFFSIDES
217Occult blood positiveOFFSIDES
218OliguriaOFFSIDES
219Optic Disc EdemaOFFSIDES
220Optic NeuritisOFFSIDES
221Oral mucosal exfoliationOFFSIDES
222OsteolysisOFFSIDES
223OsteomyelitisOFFSIDES
224Osteoporosis, Postmenopausal10750555CTD
225Osteoporosis20069278CTD
226PCO2 decreasedOFFSIDES
227ParaparesisOFFSIDES
228ParaplegiaOFFSIDES
229PeriostitisOFFSIDES
230Peripheral occlusive diseaseOFFSIDES
231Peritoneal DialysisOFFSIDES
232Peritoneal cloudy effluentOFFSIDES
233Peritoneal lesionOFFSIDES
234PeritonitisOFFSIDES
235PertussisOFFSIDES
236Platelet TransfusionOFFSIDES
237PleurisyOFFSIDES
238Pneumocystis jiroveci pneumoniaOFFSIDES
239PolymyositisOFFSIDES
240Polyomavirus-associated nephropathyOFFSIDES
241Postoperative constipationOFFSIDES
242Procedural hypotensionOFFSIDES
243Productive CoughOFFSIDES
244Protein total decreasedOFFSIDES
245Protein-losing gastroenteropathyOFFSIDES
246Prothrombin time abnormalOFFSIDES
247Psychiatric symptomOFFSIDES
248Pulmonary artery thrombosisOFFSIDES
249Pulmonary hilar enlargementOFFSIDES
250Pulmonary sepsisOFFSIDES
251PurulenceOFFSIDES
252Purulent dischargeOFFSIDES
253Pyloric StenosisOFFSIDES
254Pyoderma GangrenosumOFFSIDES
255Renal ColicOFFSIDES
256Renal tubular acidosisOFFSIDES
257Renin increasedOFFSIDES
258Residual urineOFFSIDES
259Respiratory Tract Infections21617088CTD
260Reticulocyte count decreasedOFFSIDES
261Retinal Vein OcclusionOFFSIDES
262Retinal pigment epithelial tearOFFSIDES
263RhabdomyolysisOFFSIDES
264Rickets

View details

CTD
265ScabOFFSIDES
266Sclerosing encapsulating peritonitisOFFSIDES
267ScotomaOFFSIDES
268SerositisOFFSIDES
269Shunt malfunctionOFFSIDES
270Shunt occlusionOFFSIDES
271Shunt thrombosisOFFSIDES
272Sigmoidoscopy abnormalOFFSIDES
273Skin ErosionOFFSIDES
274Skin hypertrophyOFFSIDES
275Soft tissue inflammationOFFSIDES
276Speech rehabilitationOFFSIDES
277SpondylitisOFFSIDES
278Sputum retentionOFFSIDES
279Stevens-Johnson SyndromeOFFSIDES
280Subcutaneous EmphysemaOFFSIDES
281Sudden onset of sleepOFFSIDES
282TachyphylaxisOFFSIDES
283TetanyOFFSIDES
284ThoracotomyOFFSIDES
285ThyroiditisOFFSIDES
286Tolosa-Hunt SyndromeOFFSIDES
287Umbilical herniaOFFSIDES
288Unresponsive to verbal stimuliOFFSIDES
289Upper respiratory tract inflammationOFFSIDES
290Urea urine increasedOFFSIDES
291Ureteric anastomosis complicationOFFSIDES
292Urine nitrogenOFFSIDES
293Uterine CancerOFFSIDES
294Vascular bypass graftOFFSIDES
295Ventricular FlutterOFFSIDES
296Vertebrobasilar InsufficiencyOFFSIDES
297VitrectomyOFFSIDES
298Weight Gain12960676CTD
299XanthopsiaOFFSIDES
300jejunitisOFFSIDES
301kyphosisOFFSIDES
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