MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Vincristine

(OGWKCGZFUXNPDA-XQKSVPLYSA-N)

Structure

SMILES: O=CN1c2cc(OC)c(cc2[C@]23[C@@H]1[C@@](O)(C(=O)OC)[C@H](OC(=O)C)[C@]1([C@@H]3N(CC2)CC=C1)CC)[C@]1(C[C@@H]2CN(CCc3c1[nH]c1c3cccc1)C[C@](C2)(O)CC)C(=O)OC
Molecular Formula:: C46H56N4O10
Molecular Weight:: 824.958
Log P:: 4.0942
Hydrogen Bond Acceptor:: 13
Hydrogen Bond Donor:: 3
TPSA:: 171.17
CAS Number(s):: 57-22-7; 1217704-92-1

Synonym(s)

Vincristine

Leurocristine

Citomid

Farmistin

Oncovin

Oncovine

Onkocristin

Vincasar

Vincasar PFS

10.

Vincristin Bristol

11.

Vincristin medac

12.

Vincristine Sulfate

13.

Vincrisul

14.

Vintec

15.

cellcristin

16.

PFS, Vincasar

17.

Sulfate, Vincristine

External Link(s)

MeSH	D014750
PubChem Compound	5978
BindingDB	50139772
ChEBI	28445
CHEMBL	CHEMBL90555
IUPHAR/BPS Guide to PHARMACOLOGY	6785
KEGG	cpd:C07204 dr:D08679
Therapeutic Target Database	D09QVV
ZINC	85432549

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Incorrect route of drug administration	FAERS: 5		US FAERS
2	Medication Error	FAERS: 5		US FAERS
3	Polyneuropathy	FAERS: 5		OFFSIDES US FAERS
4	Vomiting	FAERS: 4	5660206 9434832	CTD SIDER US FAERS
5	Asthenia	FAERS: 3		SIDER US FAERS
6	Autonomic nervous system imbalance	FAERS: 3		US FAERS
7	Guillain-Barre Syndrome	FAERS: 3		US FAERS
8	Myalgia	FAERS: 3		SIDER US FAERS
9	Urinary Retention	FAERS: 3	182948 5286047 19936661	CTD SIDER US FAERS
10	Wrong drug administered	FAERS: 3		US FAERS
11	nervous system disorder	FAERS: 3		SIDER US FAERS
12	Autonomic neuropathy	FAERS: 2		US FAERS
13	Blood creatine phosphokinase increased	FAERS: 2		OFFSIDES US FAERS
14	Cardiac Arrest	FAERS: 2		SIDER US FAERS
15	Colitis	FAERS: 2		US FAERS
16	Constipation	FAERS: 2	View details 1319399 2857400 2859431 2861395 3974093 4163141 4294312 4343318 4352365 5660206 5813374 10499201 12368705 19936661 20921909	CTD SIDER US FAERS
17	Denervation atrophy	FAERS: 2		US FAERS
18	Depressed Level of Consciousness	FAERS: 2		US FAERS
19	Drug administration error	FAERS: 2		US FAERS
20	Flushing	FAERS: 2		US FAERS
21	Hypotension	FAERS: 2	182948	CTD SIDER US FAERS
22	Ileus	FAERS: 2	View details 182948 2997407 3974093 4294312 4348690 4352365 5813374 6937637 8534764	CTD SIDER US FAERS
23	Incorrect dose administered	FAERS: 2		US FAERS
24	Neuropathy	FAERS: 2		SIDER US FAERS
25	Neutropenia	FAERS: 2	View details 4551303 7534090 9434832 11305414 11846301	CTD SIDER US FAERS
26	Paraparesis	FAERS: 2		US FAERS
27	Peripheral motor neuropathy	FAERS: 2		SIDER US FAERS
28	Pneumonia	FAERS: 2		SIDER US FAERS
29	Transaminases increased	FAERS: 2		US FAERS
30	Urticaria	FAERS: 2		US FAERS
31	Abasia	FAERS: 1		US FAERS
32	Abdominal Pain	FAERS: 1	View details 1319399 2857400 2859431 4163141 4294312 4352365 4552812 5660206 5813374	CTD SIDER US FAERS
33	Accidental overdose	FAERS: 1		US FAERS
34	Acute myocardial infarction	FAERS: 1		US FAERS
35	Agitation	FAERS: 1		SIDER US FAERS
36	Alanine Aminotransferase Increased	FAERS: 1		OFFSIDES US FAERS
37	Anal sphincter atony	FAERS: 1		US FAERS
38	Aspartate Aminotransferase Increased	FAERS: 1		SIDER US FAERS
39	Axonal neuropathy	FAERS: 1		US FAERS
40	Back Pain	FAERS: 1		SIDER US FAERS
41	Blood electrolytes abnormal	FAERS: 1		US FAERS
42	Bone pain	FAERS: 1		OFFSIDES SIDER US FAERS
43	Cervical spine flattening	FAERS: 1		US FAERS
44	Demyelination	FAERS: 1		OFFSIDES US FAERS
45	Diastolic dysfunction	FAERS: 1		US FAERS
46	Diplegia	FAERS: 1		US FAERS
47	Drug ineffective	FAERS: 1		OFFSIDES US FAERS
48	Duodenal perforation	FAERS: 1		US FAERS
49	Dysgeusia	FAERS: 1		US FAERS
50	Epilepsy	FAERS: 1		US FAERS
51	Erythema	FAERS: 1	9571977	CTD OFFSIDES US FAERS
52	Gastrointestinal Pain	FAERS: 1		SIDER US FAERS
53	Gastrointestinal hypomotility	FAERS: 1		US FAERS
54	General physical health deterioration	FAERS: 1		OFFSIDES US FAERS
55	Headache	FAERS: 1		SIDER US FAERS
56	Hepatitis C antibody positive	FAERS: 1		US FAERS
57	Hepatitis	FAERS: 1		US FAERS
58	Hypersensitivity	FAERS: 1		SIDER US FAERS
59	Hypokinesia	FAERS: 1		US FAERS
60	Hypoxia	FAERS: 1		OFFSIDES US FAERS
61	Immediate post-injection reaction	FAERS: 1		US FAERS
62	Immunosuppression	FAERS: 1		US FAERS
63	Impaired work ability	FAERS: 1		US FAERS
64	Inflammation	FAERS: 1		US FAERS
65	Injection Site Reaction	FAERS: 1		US FAERS
66	Injection site infection	FAERS: 1		US FAERS
67	Injection site pain	FAERS: 1		US FAERS
68	Intestinal Perforation	FAERS: 1		US FAERS
69	Lethargy	FAERS: 1	6937637	CTD US FAERS
70	Malaise	FAERS: 1		US FAERS
71	Memory impairment	FAERS: 1		US FAERS
72	Meningism	FAERS: 1	284172	CTD US FAERS
73	Multiple System Atrophy	FAERS: 1		US FAERS
74	Musculoskeletal Pain	FAERS: 1		SIDER US FAERS
75	Musculoskeletal stiffness	FAERS: 1		US FAERS
76	Nerve Degeneration	FAERS: 1	View details 232962 1850399 4290103 4301062 4309019 4314181 5767018 6303274 7155172 7659949 9161096 9452187 10499201 11587867 12401321 14637374 16676325 16698718 16797537 19935391	CTD US FAERS
77	Nerve root lesion	FAERS: 1		US FAERS
78	Ophthalmoplegia	FAERS: 1	View details 4294312 4314181 5813374 16816519	CTD OFFSIDES US FAERS
79	Opisthotonus	FAERS: 1		US FAERS
80	Optic Neuropathy	FAERS: 1		US FAERS
81	Oral pruritus	FAERS: 1		US FAERS
82	Pain	FAERS: 1	View details 1329697 1654424 2862358 3025992 3044635 4314181 4343318 4352365 5813374 8622042 12368705 17280922 17659836	CTD OFFSIDES SIDER US FAERS
83	Pallor	FAERS: 1		US FAERS
84	Pancreatitis	FAERS: 1		US FAERS
85	Paresis anal sphincter	FAERS: 1		US FAERS
86	Pericardial effusion	FAERS: 1		US FAERS
87	Phlebitis	FAERS: 1		US FAERS
88	Posterior reversible encephalopathy syndrome	FAERS: 1		US FAERS
89	Product label confusion	FAERS: 1		US FAERS
90	Product label issue	FAERS: 1		US FAERS
91	Pulmonary toxicity	FAERS: 1		OFFSIDES US FAERS
92	Quadriplegia	FAERS: 1	View details 581313 3974093 4290103 10390891 12427913	CTD US FAERS
93	Quality of life decreased	FAERS: 1		US FAERS
94	Respiratory Failure	FAERS: 1		OFFSIDES SIDER US FAERS
95	Respiratory arrest	FAERS: 1		US FAERS
96	Respiratory distress	FAERS: 1		SIDER US FAERS
97	Sensorimotor disorder	FAERS: 1		US FAERS
98	Sepsis	FAERS: 1	4631913	CTD US FAERS
99	Stevens-Johnson Syndrome	FAERS: 1		US FAERS
100	Subileus	FAERS: 1		OFFSIDES US FAERS
101	Supraventricular tachycardia	FAERS: 1		OFFSIDES US FAERS
102	Thrombophlebitis	FAERS: 1		US FAERS
103	Toxic Epidermal Necrolysis	FAERS: 1		US FAERS
104	Wheezing	FAERS: 1		US FAERS
105	Abdominal Cramps			SIDER
106	Abdominal colic			SIDER
107	Abdominal discomfort			OFFSIDES
108	Abdominal symptom			OFFSIDES
109	Abducens Nerve Diseases		5813374 14970803 14970804	CTD
110	Abnormal vision			OFFSIDES
111	Abscess			OFFSIDES
112	Acanthosis			OFFSIDES
113	Actinic keratosis			OFFSIDES
114	Actinomycosis			OFFSIDES
115	Activities of daily living impaired			OFFSIDES
116	Acute Coronary Syndrome			SIDER
117	Acute kidney injury		10454517	CTD
118	Acute sinusitis			OFFSIDES
119	Adenocarcinoma		675898 6340628 19825857	CTD
120	Adrenocortical carcinoma		12015757	CTD
121	Agranulocytosis		5813374	CTD
122	Alcohol poisoning			OFFSIDES
123	Alkalosis		582354	CTD OFFSIDES
124	Allogenic bone marrow transplantation therapy			OFFSIDES
125	Alopecia		View details 2862358 4294312 4348690 4352365 4551303 4559404 5067790 5254045 5660206 5813374 24374478 29958920	CTD OFFSIDES SIDER
126	Altered state of consciousness			OFFSIDES SIDER
127	Alveoloplasty			OFFSIDES
128	Amimia			OFFSIDES
129	Amnestic Disorder			OFFSIDES
130	Amyloidosis			OFFSIDES
131	Anaphylactic shock			SIDER
132	Anemia		View details 4551437 4552812 5813374 11846301	CTD
133	Anger			OFFSIDES
134	Angina Pectoris		11724093	CTD
135	Anhidrosis			OFFSIDES
136	Anorexia		4294312 5660206 17109847	CTD SIDER
137	Anosmia			OFFSIDES
138	Antidepressant drug clearance decreased			OFFSIDES
139	Anxiety			OFFSIDES
140	Aphasia		17356399 19936661 20363963	CTD
141	Aphonia		3152952	CTD
142	Application site cellulitis			OFFSIDES
143	Artificial crown procedure			OFFSIDES
144	Ascites		6937637	CTD
145	Astrocytoma		View details 185991 939971 1312230 1432038 3171334 8186424	CTD
146	Ataxia		657152	CTD OFFSIDES SIDER
147	Atelectasis			OFFSIDES
148	Athetosis		657152 6316187	CTD
149	Atrial tachycardia			OFFSIDES
150	Autoimmune thrombocytopenia			OFFSIDES
151	Azotemia		4833837	CTD
152	B-cell lymphoma recurrent			OFFSIDES
153	BK virus infection			OFFSIDES
154	Back disorder			OFFSIDES
155	Bacterial sepsis			OFFSIDES
156	Bedridden			OFFSIDES
157	Beta 2 microglobulin increased			OFFSIDES
158	Beta-N-acetyl-D-glucosaminidase increased			OFFSIDES
159	Biopsy bone abnormal			OFFSIDES
160	Bipolar Disorder			OFFSIDES
161	Blast cell count increased			OFFSIDES
162	Blepharitis			OFFSIDES
163	Blepharoptosis		View details 4294312 5813374 15838404 16816519	CTD OFFSIDES
164	Blepharospasm			OFFSIDES
165	Blindness, Cortical		7459813 14515391	CTD
166	Blindness		View details 1377296 1497023 6894223 19936661	CTD SIDER
167	Blood amylase increased			OFFSIDES
168	Blood and lymphatic system disorders			SIDER
169	Blood blister			OFFSIDES
170	Blood cholesterol			OFFSIDES
171	Blood fibrinogen			OFFSIDES
172	Blood immunoglobulin A increased			OFFSIDES
173	Blood immunoglobulin M			OFFSIDES
174	Blood lactate dehydrogenase increased			OFFSIDES
175	Blood phosphorus decreased			OFFSIDES
176	Blood sodium abnormal			OFFSIDES
177	Blood sodium increased			OFFSIDES
178	Blood sodium			OFFSIDES
179	Blood triglycerides increased			OFFSIDES
180	Blood urea abnormal			OFFSIDES
181	Bone Marrow Neoplasms		2214347	CTD
182	Bone Sarcoma			OFFSIDES
183	Bone lesion			OFFSIDES
184	Bone marrow depression			SIDER
185	Brain Concussion			OFFSIDES
186	Brain Diseases		View details 284172 1280054 3469437 4848646 5767018 6328836 6738836 6893362 7931469 19936661	CTD
187	Brain Infarction			SIDER
188	Brain Injuries		8413926	CTD
189	Brain Neoplasms		View details 185991 939971 1312230 6773738 7931469 8186424 9760072 15543016	CTD
190	Bronchitis			OFFSIDES
191	Bronchoalveolar Lavage			OFFSIDES
192	Bruxism			OFFSIDES
193	Burkitt Lymphoma		View details 3965085 9186541 18782177 25023062	CTD
194	Bursitis			OFFSIDES
195	CYTOMEGALOVIRUS ANTIGEN			OFFSIDES
196	Calciphylaxis			OFFSIDES
197	Candida serology positive			OFFSIDES
198	Capillary Leak Syndrome			OFFSIDES
199	Carcinoma, Small Cell		165045	CTD
200	Carcinoma, Transitional Cell		8602639	CTD
201	Carcinoma		4352365 6964043 7844616	CTD
202	Cardiomegaly		25537132	CTD
203	Cardiomyopathies		6940649 24201307 25537132	CTD
204	Cardiotoxicity			OFFSIDES
205	Catheter placement			OFFSIDES
206	Catheter related infection			OFFSIDES
207	Cellulitis			OFFSIDES
208	Central Nervous System Neoplasms		3359561 10963643	CTD
209	Central line infection			OFFSIDES
210	Central venous catheter removal			OFFSIDES
211	Cerebellar Diseases		12401321	CTD
212	Cerebral Hemorrhage		7931469	CTD
213	Cerebral Infarction			SIDER
214	Cervicobrachial syndrome			OFFSIDES
215	Charcot-Marie-Tooth Disease		View details 8600343 10519723 12679647 12756314 15382281 18837430	CTD
216	Charles Bonnet Syndrome			OFFSIDES
217	Chemical and Drug Induced Liver Injury		6937637	CTD
218	Choking sensation			OFFSIDES
219	Cholangiolitis			OFFSIDES
220	Cholestatic liver injury			OFFSIDES
221	Chordoma		4528471	CTD
222	Chorea		6316187	CTD
223	Chronic sinusitis			OFFSIDES
224	Circumstance or information capable of leading to medication error			OFFSIDES
225	Colectomy			OFFSIDES
226	Colon adenoma			OFFSIDES
227	Colonic Pseudo-Obstruction			SIDER
228	Colorectal Neoplasms		7960606	CTD
229	Complete Hearing Loss			SIDER
230	Compression fracture			OFFSIDES
231	Confusion		7099798 19936661	CTD
232	Congenital hypertrichosis			OFFSIDES
233	Conjunctival deposit			OFFSIDES
234	Cor pulmonale			OFFSIDES
235	Corneal Diseases		4294312	CTD
236	Coronary Artery Disease			SIDER
237	Coronary Thrombosis		11724093	CTD
238	Cranial nerve diseases		View details 182948 4290103 6385604 10390891 15838404 17710662 18754106	CTD
239	Cyanosis			OFFSIDES
240	Cystitis		4551437 8518042	CTD
241	Deafness Neurosensory			OFFSIDES
242	Deafness			SIDER
243	Debridement			OFFSIDES
244	Decreased vibratory sense			SIDER
245	Deglutition Disorders		10942065 20167372	CTD
246	Dehydration			SIDER
247	Delayed engraftment			OFFSIDES
248	Demyelinating Diseases		View details 1497023 4290103 4314181 6303274 8600343 9452187 11587867 16698718 17279013 18766974 19935391	CTD
249	Dental Fistula			OFFSIDES
250	Dental caries			OFFSIDES
251	Depressed mood			OFFSIDES
252	Dermatitis			SIDER
253	Desmoplastic Small Round Cell Tumor		10555010	CTD
254	Device related infection			OFFSIDES
255	Diabetes mellitus inadequate control			OFFSIDES
256	Diarrhea		4294312 7534090 29958920	CTD OFFSIDES
257	Diffuse Large B-Cell Lymphoma			OFFSIDES
258	Diffuse alveolar damage			OFFSIDES
259	Diplopia		5813374	CTD
260	Disease Progression			OFFSIDES
261	Disease recurrence			OFFSIDES
262	Disorders of Excessive Somnolence		9571977	CTD
263	Disseminated Intravascular Coagulation			OFFSIDES
264	Dizziness			OFFSIDES SIDER
265	Drowsiness			OFFSIDES
266	Drug Overdose		182948 5159844	CTD
267	Drug resistance			OFFSIDES
268	Drug withdrawal headache			OFFSIDES
269	Dysarthria		10942065 20167372 20363963	CTD
270	Dysmenorrhea			OFFSIDES
271	Dysphonia		16696885	CTD
272	Dystonia			OFFSIDES
273	Dysuria			SIDER
274	Early satiety			OFFSIDES
275	Ecthyma			OFFSIDES
276	Eczema			OFFSIDES
277	Edema		6937637	CTD
278	Ejection Fraction Decreased			OFFSIDES
279	Emotional distress			OFFSIDES
280	Encephalitis			OFFSIDES
281	Eosinophilia		4551437	CTD
282	Ependymoma		3359561 16609949	CTD
283	Epistaxis			OFFSIDES
284	Epstein-Barr virus associated lymphoproliferative disorder			OFFSIDES
285	Epstein-Barr virus test positive			OFFSIDES
286	Erectile dysfunction			SIDER
287	Erosive balanitis			OFFSIDES
288	Erosive gastritis			OFFSIDES
289	Erythema Nodosum			OFFSIDES
290	Escherichia infection			OFFSIDES
291	Esophageal Neoplasms		7844616	CTD
292	Esophageal Stenosis			OFFSIDES
293	Exanthema		9434832	CTD
294	Extravasation			SIDER
295	Eye Infection			OFFSIDES
296	Facial Nerve Diseases		4294312 5813374 20167372	CTD
297	Facial Pain		View details 1319399 1407990 2857400 3974093 4163141 5813374	CTD
298	Facial paralysis		4309695 19770526	CTD SIDER
299	Failure to Thrive			OFFSIDES
300	Fatigue		6293321	CTD OFFSIDES SIDER
301	Fatty Liver			OFFSIDES
302	Febrile Neutropenia			OFFSIDES SIDER
303	Febrile bone marrow aplasia			OFFSIDES
304	Fecal Incontinence		9375755	CTD
305	Fever		179476 2636248	CTD
306	Fistula repair			OFFSIDES
307	Food Poisoning			OFFSIDES
308	Foot Deformities		4009878 8600343	CTD
309	Formication			OFFSIDES
310	Fungus serology test positive			OFFSIDES
311	Gagging		16609949	CTD
312	Gait Ataxia		4294312	CTD
313	Gait Disorders, Neurologic		View details 1319399 3152952 8859020 24374478	CTD
314	Gallop rhythm present			OFFSIDES
315	Gastroenteritis bacillus			OFFSIDES
316	Gastrointestinal Diseases		View details 1939879 4294312 5254045 6089632 6150069 7960606	CTD
317	Gastrointestinal arteriovenous malformation			OFFSIDES
318	Gastrointestinal toxicity			OFFSIDES
319	Gastroparesis		19448908	CTD
320	Gene Mutation			OFFSIDES
321	Gingival Hypertrophy			OFFSIDES
322	Glioma		1662522 12874004 19901110	CTD
323	Gliosis		1497023	CTD OFFSIDES
324	Gram stain positive			OFFSIDES
325	Granuloma			OFFSIDES
326	Haematotoxicity			OFFSIDES
327	Hallucinations		7537641 17356399	CTD
328	Hearing Loss, Bilateral		7272895 11154039 12868558	CTD
329	Hearing Loss, Sudden		12868558	CTD
330	Hearing Loss		18669462 19415035	CTD
331	Heart Diseases		3169098 7466925	CTD
332	Hemangioblastoma		3359561	CTD
333	Hematoma, Subdural		7931469	CTD
334	Hematuria		8518042 8602639 12748258	CTD
335	Hemiplegia		20363963	CTD
336	Hemolytic-Uremic Syndrome		View details 1699855 2482985 6846975 11037870	CTD
337	Hepatic Veno-Occlusive Disease		View details 9191535 9251728 11194540 15981233 18839274 19701718	CTD
338	Hepatitis B positive			OFFSIDES
339	Hepatitis B virus test			OFFSIDES
340	Hepatitis B			OFFSIDES
341	Hepatomegaly		6287875 6937637	CTD
342	Hepatosplenic candidiasis			OFFSIDES
343	Hepatosplenomegaly			OFFSIDES
344	Hepatotoxicity			OFFSIDES
345	Hip surgery			OFFSIDES
346	Hoarseness		16609949	CTD
347	Hodgkin Disease		View details 934199 1329697 2531872 4007346 4348690 4352365 4916023 6089632 6092732 6459048 6896575 7313841 15147373 15922437 16135485 16794504 17290056 17606976 17701600 18293384 19770686	CTD
348	Hyperalgesia		View details 8783247 9452187 9619501 9698336 10321468 11983324 12749967 12759171 12809704 12865165 14637374 15082137 15235822 15713428 15875786 16098672 16472913 16530953 16545521 16556439 16632831 16676325 16982702 17572696 17989505 18234883 18492948 18652822 18766156 18799818 18930597 18938155 19276613 19300402 19336915 19448908 19571391 19815945 20081245 20431905 20830263 20846523 26102012 27474498	CTD
349	Hyperbilirubinemia		6937637	CTD
350	Hypercapnia			OFFSIDES
351	Hyperkalemia		4833837	CTD
352	Hyperpigmentation			OFFSIDES
353	Hypesthesia		View details 1329697 4294312 4343318 8859020 20379113	CTD
354	Hypocalcemia		4833837	CTD
355	Hypokalemia		582354	CTD
356	Hyponatremia		View details 4356234 4974027 12051122 12368705	CTD
357	Hyporeflexia			OFFSIDES SIDER
358	Hypotension, Orthostatic		View details 1148735 4393517 6396566 7407771	CTD
359	Iatrogenic Disease		View details 1280054 1895154 6573227 6893362 9856687 11587867 19935391	CTD
360	Incision site infection			OFFSIDES
361	Infection			OFFSIDES SIDER
362	Infusion site mobility decreased			OFFSIDES
363	Intervertebral disc disorder			OFFSIDES
364	Intestinal Obstruction			SIDER
365	Intestinal Pseudo-Obstruction		9434832	CTD
366	Intestinal necrosis			SIDER
367	Intracranial Aneurysm			OFFSIDES
368	Intracranial Hypotension			OFFSIDES
369	Intracranial Thrombosis		3111251	CTD
370	JC virus infection			OFFSIDES
371	Kidney Diseases		11305414	CTD
372	Kidney Failure			OFFSIDES
373	Leukemia, Myelomonocytic, Chronic		15981233	CTD
374	Leukemia, Plasma Cell		4571885	CTD
375	Leukemia, T-Cell		18766974	CTD
376	Leukoencephalopathy			OFFSIDES
377	Leukopenia neonatal			OFFSIDES
378	Leukopenia		View details 2997407 4352365 4551437 4631913 5660206 7960606	CTD SIDER
379	Life expectancy shortened			OFFSIDES
380	Limb discomfort			OFFSIDES
381	Lip erosion			OFFSIDES
382	Liver Abscess			OFFSIDES
383	Liver diseases		169340	CTD
384	Lumbar radiculopathy			OFFSIDES
385	Lung Neoplasms		6189445 6964043 19825857	CTD
386	Lupus Erythematosus, Systemic		1696192	CTD
387	Lymphangitis			OFFSIDES
388	Lymphocyte count decreased			OFFSIDES
389	Lymphocyte stimulation test positive			OFFSIDES
390	Lymphoma, AIDS-Related		8697399	CTD
391	Lymphoma, Extranodal NK-T-Cell		20839428	CTD
392	Lymphoma, Non-Hodgkin		View details 403727 581313 582354 657152 1243105 1329697 2217048 2861395 2872506 4301062 4348690 4352365 4393517 4551303 4916023 6429913 6683953 6722721 6894223 7155172 8384253 12172056 12427913 14970804	CTD
393	Lymphoma		View details 630255 4512319 6396566 9571977 9681210 10963643 16546662 21986259	CTD OFFSIDES
394	Lymphoplasmacytoid lymphoma/immunocytoma			OFFSIDES
395	Lysosomal Storage Diseases		28551711	CTD
396	Macroglossia			OFFSIDES
397	Malignant neoplasm progression			OFFSIDES
398	Malignant tumour excision			OFFSIDES
399	Mass excision			OFFSIDES
400	Mastication disorder			OFFSIDES
401	Mechanical ventilation			OFFSIDES
402	Mediastinal mass			OFFSIDES
403	Medulloblastoma		View details 939971 3359561 7099798 19701718 19890797	CTD
404	Melanoma, Amelanotic		15990972	CTD
405	Meningoencephalitis		6573227	CTD
406	Menorrhagia			SIDER
407	Mental status changes			SIDER
408	Metamyelocyte percentage increased			OFFSIDES
409	Metaplasia			OFFSIDES
410	Micronuclei, Chromosome-Defective		30944280	CTD
411	Mononeuritis			OFFSIDES
412	Mononeuropathies		169494	CTD
413	Motor Neuron Disease		10390891 11241435	CTD
414	Motor Skills Disorders		12401321	CTD
415	Mouth Neoplasms		2482985	CTD
416	Movement Disorders		View details 1654424 3025992 8859020 21494842	CTD
417	Mucormycosis			OFFSIDES
418	Multiple Myeloma		View details 1445746 3838922 11154039 12791655 15528922 15609275 17050881 17097782 17355553 20864405 25672400	CTD OFFSIDES
419	Multiple Sclerosis			OFFSIDES
420	Muscle Cramp		1659838	CTD
421	Muscle Weakness		View details 284172 1329697 2861395 2862358 3152952 3974093 4009878 4046919 4294312 4301062 4314181 4348690 4352365 5027400 5660206 5813374 8534764 8600343 8622042 10519723 10942065 12427913 17356399 19936661	CTD OFFSIDES
422	Muscle hypotonia		1939879 16609949	CTD
423	Muscle strain			OFFSIDES
424	Muscular Atrophy		View details 4290103 4294312 4314181 5813374	CTD
425	Musculoskeletal chest pain			OFFSIDES
426	Musculoskeletal discomfort			SIDER
427	Mycosis Fungoides		1850399	CTD
428	Myeloblast count increased			OFFSIDES
429	Myelocyte percentage increased			OFFSIDES
430	Myelocytosis			OFFSIDES
431	Myelodysplasia			OFFSIDES
432	Myeloma recurrence			OFFSIDES
433	Myelosuppression			SIDER
434	Myocardial Infarction		View details 693307 1243105 3960084 4007346 7313841 7572766 8781842 9415359 11724093 17284715	CTD SIDER
435	Myocardial Ischemia		7809448	CTD
436	Myocardial fibrosis			OFFSIDES
437	Myoclonus			SIDER
438	Myotonic Disorders		934199	CTD
439	Nausea		4294312 5660206	CTD SIDER
440	Necrosis		View details 6573227 10730638 24201307 25537132	CTD
441	Neoplasm Metastasis		7960606	CTD
442	Neoplasms, Bone Tissue		278643	CTD
443	Neoplasms, Experimental		24154679 25672400	CTD
444	Neoplasms, Neuroepithelial		12325066	CTD
445	Nephrotic Syndrome		9655358	CTD
446	Neuralgia		View details 1324459 5660206 9619501 10321468 12710988 14637374 15713428 16472913 19936661 20846523 26102012	CTD
447	Neuritis			SIDER
448	Neuroaxonal Dystrophies		857581	CTD
449	Neurobehavioral Manifestations		8413926 12401321	CTD
450	Neuroblastoma		857581 4294312 18353067	CTD
451	Neuroectodermal Tumors		12837982	CTD
452	Neuromuscular Diseases		278643 2997407 5254045	CTD
453	Neuromuscular Junction Diseases		172049	CTD
454	Neuropathy, Painful		27474498	CTD
455	Neurotoxicity Syndromes		View details 105807 182948 630255 1407990 1654424 2363100 2857400 2897788 3327022 3477471 3488849 4009878 6125275 6149015 6150069 6316187 6473007 6722721 6964043 7074557 8608515 9681224 10553948 11255732 11335041 11587867 11957264 15330181 17023056 17572696 18714154 18797198 19770526 19936661 20921909 21225912 26102012	CTD
456	Neutropenic colitis			OFFSIDES
457	Neutropenic infection			OFFSIDES
458	Neutropenic sepsis			OFFSIDES
459	Neutrophil count abnormal			OFFSIDES
460	Neutrophil count decreased			OFFSIDES
461	Nodule on extremity			OFFSIDES
462	Nodule			OFFSIDES
463	Nuclear magnetic resonance imaging brain			OFFSIDES
464	Numbness			SIDER
465	Nutritional condition abnormal			OFFSIDES
466	Nystagmus			SIDER
467	Olfaction Disorders		16698718	CTD
468	Oliguria			OFFSIDES
469	Optic Atrophy		View details 813350 1497023 6894223 7099798	CTD SIDER
470	Optic Nerve Glioma		16936459	CTD
471	Optic Neuritis			OFFSIDES
472	Oral Ulcer		6937637	CTD
473	Oral infection			OFFSIDES
474	Oral mucosal exfoliation			OFFSIDES
475	Orchitis			OFFSIDES
476	Oropharyngeal pain			OFFSIDES
477	Orthopnea			OFFSIDES
478	Osteolysis			OFFSIDES
479	Osteomyelitis			OFFSIDES
480	Osteopenia			OFFSIDES
481	Osteoporosis			OFFSIDES
482	Osteosarcoma recurrent			OFFSIDES
483	Osteosarcoma		View details 310278 857581 6940649 22016816	CTD
484	Overweight			OFFSIDES
485	Pancytopenia			SIDER
486	Paraplegia		9375755	CTD OFFSIDES
487	Paresis		1329697 6316187	CTD SIDER
488	Paresthesia		View details 581313 1329697 1654424 1939879 2861395 2862358 2897788 2997407 3974093 4290103 4294312 4301062 4309019 4314181 4343318 4348690 4352365 4559404 4608355 5027400 5660206 5813374 7511314 8534764 10499201 10942065 12116067 12427913 17097782 20921909	CTD
489	Peripheral Nervous System Diseases		View details 172049 182948 1148735 1390351 1497023 1659838 1850399 1964745 2555214 2995593 3009012 4294312 4301062 4309019 4314181 4348690 4356234 6245189 6285279 6303274 6385604 6683953 6937637 7099798 7511314 7659949 8444217 8771166 8866126 9452187 9698336 10321468 10499201 10741703 10931481 11241435 11305414 11957264 12116067 12427913 12679647 12710988 12865165 14637374 15382281 15781834 16698718 16797537 17279013 17280922 17659836 17710662 18176183 18270703 18754106 18837430 19300402 19815945 19909482 19936661 20216233 20431905 20433602 20830263 20864405 21225912 24374478 26102012 29958920	CTD
490	Physical disability			OFFSIDES
491	Pilonidal Cyst			OFFSIDES
492	Plasmacytoma			OFFSIDES
493	Platelet Transfusion			OFFSIDES
494	Platelet adhesiveness increased			OFFSIDES
495	Pneumocystis jiroveci pneumonia			OFFSIDES
496	Poisoning		23649840	CTD
497	Polymyalgia Rheumatica			OFFSIDES
498	Polyradiculoneuropathy		17594344	CTD
499	Polyuria			SIDER
500	Poor sucking reflex			OFFSIDES
501	Portal Hypertension			OFFSIDES
502	Posturing			OFFSIDES
503	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma		View details 16816519 17710662 18176182 18191947 21064136 21225912 24154679	CTD
504	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma		12426685 20167372 20463610	CTD
505	Primary mediastinal large B-cell lymphoma stage II			OFFSIDES
506	Primary sequestrum			OFFSIDES
507	Prolonged menses			SIDER
508	Prostatic Neoplasms		6340628	CTD
509	Prothrombin time abnormal			OFFSIDES
510	Pseudomonas Infections		4631913	CTD
511	Pulmonary function test decreased			OFFSIDES
512	Radiation associated pain			OFFSIDES
513	Rales			OFFSIDES
514	Raynaud Disease		6846998 7689922 15543016	CTD
515	Recurrence		2214347	CTD
516	Reflex, Abnormal		View details 284172 581313 1319399 1329697 2861395 2897788 3152952 3974093 4290103 4294312 4301062 4309019 4309695 4314181 4343318 4348690 4352365 4356234 4552812 4559404 5660206 5813374 6245189 6265865 6285279 7511314 8600343 10499201 10942065 11030069 12427913 19936661 20921909	CTD
517	Renal Insufficiency		12844235	CTD
518	Renal interstitial fibrosis			OFFSIDES
519	Respiratory Insufficiency		5027400	CTD
520	Respiratory Paralysis		284172	CTD
521	Respiratory Sounds		View details 1405987 1939879 11882230 16609949 16696885 20505534	CTD
522	Respiratory tract congestion			OFFSIDES
523	Reticulocyte count increased			OFFSIDES
524	Retinal Degeneration		813350 1497023	CTD
525	Retinal infarction			OFFSIDES
526	Retrograde Degeneration		View details 1497023 1964745 6245189 6265865 16930282 17267126	CTD
527	Rhabdomyosarcoma		View details 857581 9191535 11846301 18989167	CTD
528	Right Ventricular Hypertrophy			OFFSIDES
529	Risus sardonicus			OFFSIDES
530	Sciatic Neuropathy		9161096 26102012	CTD
531	Seizures		View details 179476 182948 1319399 2859431 3164090 4512319 5660206 6429913 9434832 15794179 17031686 19936661	CTD
532	Sensation Disorders		8384253	CTD
533	Septic Shock			SIDER
534	Sequestrectomy			OFFSIDES
535	Serum Sickness			OFFSIDES
536	Shunt malfunction			OFFSIDES
537	Sick Sinus Syndrome			OFFSIDES
538	Sinus headache			OFFSIDES
539	Sinus operation			OFFSIDES
540	Sinus rhythm			OFFSIDES
541	Sinusitis			OFFSIDES
542	Skin Neoplasms		20431905	CTD
543	Skin laceration			OFFSIDES
544	Skin lesion			OFFSIDES
545	Small intestine carcinoma			OFFSIDES
546	Soft Tissue Infection			OFFSIDES
547	Soft tissue inflammation			OFFSIDES
548	Somatosensory Disorders		19936661	CTD
549	Spinal Cord Neoplasms		3171334	CTD
550	Spinal Neoplasms		4528471	CTD
551	Spinal column stenosis			OFFSIDES
552	Splenectomy			OFFSIDES
553	Splenomegaly		6937637	CTD
554	Stem cell transplant			OFFSIDES
555	Stomatitis		4294312	CTD SIDER
556	Stress ulcer			OFFSIDES
557	Stridor			OFFSIDES
558	Subcutaneous nodule			OFFSIDES
559	Subdural Effusion			OFFSIDES
560	Sudden Cardiac Death			SIDER
561	Superior Vena Cava Syndrome		19018221 19770526	CTD
562	Supratentorial Neoplasms		12837982	CTD
563	Sweating			SIDER
564	Synovial Cyst			OFFSIDES
565	T-Cell Lymphoma			OFFSIDES
566	Temporal Arteritis			OFFSIDES
567	Teratoma		2859431	CTD
568	Terminal state			OFFSIDES
569	Testicular Neoplasms		5027400	CTD
570	Thoracic cavity drainage			OFFSIDES
571	Thrombocytopenia		View details 2981498 2997407 4352365 4551437 4552812 5813374 11305414 11846301	CTD SIDER
572	Thromboembolism		7960606	CTD
573	Thrombosis		2946315 3875694	CTD
574	Thyroiditis			OFFSIDES
575	Tinnitus		19415035	CTD OFFSIDES
576	Tooth Extraction			OFFSIDES
577	Transfusion-Related Acute Lung Injury			OFFSIDES
578	Treatment related secondary malignancy			OFFSIDES
579	Tremor		4518764	CTD
580	Unresponsive to pain stimuli			OFFSIDES
581	Urate nephropathy			SIDER
582	Uremia		582354	CTD
583	Urinary Bladder Diseases		5286047 15891567	CTD
584	Urinary Incontinence		17356399	CTD
585	Urinary Tract Pain			OFFSIDES
586	Urinary sediment abnormal			OFFSIDES
587	Urinary sediment present			OFFSIDES
588	Urination Disorders		5813374	CTD
589	Urine cytomegalovirus positive			OFFSIDES
590	Urine output increased			SIDER
591	VIIth nerve paralysis			SIDER
592	Vaginal obstruction			OFFSIDES
593	Vascular graft complication			OFFSIDES
594	Vasospasm, Intracranial		17356399	CTD
595	Vena cava filter insertion			OFFSIDES
596	Vertigo			SIDER
597	Viral pharyngitis			OFFSIDES
598	Vision Disorders		4352365	CTD
599	Vitamin B 12 Deficiency			OFFSIDES
600	Vocal Cord Paralysis		View details 1405987 1939879 10578547 11882230 16546662 16609949 16696885 19179723 20505534	CTD SIDER
601	Voice Disorders		1654424 4352365 9681210	CTD
602	Vulvovaginal adhesion			OFFSIDES
603	Wallerian Degeneration		539376	CTD
604	Water-Electrolyte Imbalance		582354	CTD
605	Weight decreased			SIDER
606	Wound Complication			OFFSIDES
607	Xerosis			OFFSIDES
608	anaphylaxis		19018221	CTD
609	colonoscopy			OFFSIDES
610	fibroma			OFFSIDES
611	leiomyosarcoma		1421432 7844616 12748258	CTD
612	leukemia		View details 581272 630255 3875694 4163141 5286047 5660206 6149015	CTD
613	oligodendroglioma		View details 7931469 15015656 19901104 20842591 21246521	CTD

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