MetaADEDB 2.0 @ LMMD
Ketorolac
(OZWKMVRBQXNZKK-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1
Type(s)
Approved
ATC code(s)
M01AB15; S01BC05; S01FB51
Molecular Formula:
C15H13NO3
Molecular Weight:
255.269
Log P:
2.2910
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
59.3
CAS Number(s):
66635-83-4; 74103-06-3; 74103-07-4
Synonym(s)
1.
Ketorolac
External Link(s)
MeSHD020910
PubChem Compound3826
BindingDB50009855
85511
ChEBI76223
6129
CHEMBLCHEMBL469
DrugBankDB00465
DrugCentral1529
IUPHAR/BPS Guide to PHARMACOLOGY6661
KEGGcpd:C07062
dr:D08104
Therapeutic Target DatabaseD0D9JW
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1HypersensitivityFAERS: 14SIDER
US FAERS
2Incorrect drug administration durationFAERS: 11US FAERS
3NauseaFAERS: 11
Canada Vigilance: 2		12224377CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
4Product quality issueFAERS: 11US FAERS
5Injection site painFAERS: 10SIDER
US FAERS
6Drug administration errorFAERS: 9OFFSIDES
US FAERS
7HeadacheFAERS: 9
Canada Vigilance: 4		11867972CTD
SIDER
Canada Vigilance
US FAERS
8DizzinessFAERS: 8
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
9Injection site erythemaFAERS: 7US FAERS
10AsthmaFAERS: 6SIDER
US FAERS
11Back PainFAERS: 6
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
12Chest PainFAERS: 6
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
13PainFAERS: 6
Canada Vigilance: 1

View details

2785813
7571027
9882077
10100293
11474276
12190806
15102535
18165188
18215494
19459639
 		CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
14UrticariaFAERS: 611792017CTD
SIDER
US FAERS
15VomitingFAERS: 612224377CTD
SIDER
US FAERS
16Drug ineffectiveFAERS: 5
Canada Vigilance: 4		Canada Vigilance
US FAERS
17Eye irritationFAERS: 5SIDER
US FAERS
18RhabdomyolysisFAERS: 5US FAERS
19Drug prescribing errorFAERS: 4US FAERS
20GastritisFAERS: 4SIDER
US FAERS
21NephrolithiasisFAERS: 4OFFSIDES
US FAERS
22Peripheral swellingFAERS: 4US FAERS
23Poor quality drug administeredFAERS: 4US FAERS
24Product use in unapproved indicationFAERS: 4US FAERS
25PruritusFAERS: 4SIDER
US FAERS
26Abdominal PainFAERS: 3OFFSIDES
SIDER
US FAERS
27AngioedemaFAERS: 38189303CTD
SIDER
US FAERS
28AnxietyFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
29ArthralgiaFAERS: 3SIDER
US FAERS
30Chest discomfortFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
31Contraindicated drug prescribedFAERS: 3US FAERS
32FatigueFAERS: 3SIDER
US FAERS
33HypotensionFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
34Injection Site ReactionFAERS: 3SIDER
US FAERS
35MalaiseFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
36Neck PainFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
37AstheniaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
38Blood creatinine increasedFAERS: 2SIDER
US FAERS
39Contraindicated product administeredFAERS: 2US FAERS
40DiscomfortFAERS: 2SIDER
US FAERS
41Drug abuseFAERS: 2US FAERS
42Duodenal UlcerFAERS: 2OFFSIDES
SIDER
US FAERS
43DuodenitisFAERS: 2US FAERS
44ErythemaFAERS: 2SIDER
US FAERS
45Eye painFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
46Gastric ulcerFAERS: 2OFFSIDES
SIDER
US FAERS
47Injection site bruisingFAERS: 2US FAERS
48KeratitisFAERS: 2SIDER
US FAERS
49Lip swellingFAERS: 2US FAERS
50Musculoskeletal PainFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
51MyalgiaFAERS: 2SIDER
US FAERS
52NervousnessFAERS: 2SIDER
US FAERS
53Perforated ulcerFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
54PneumoniaFAERS: 2SIDER
US FAERS
55Prescription drug used without a prescriptionFAERS: 2US FAERS
56Product contamination physicalFAERS: 2US FAERS
57Pulmonary function test decreasedFAERS: 2SIDER
US FAERS
58SomnolenceFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
59TachycardiaFAERS: 2SIDER
US FAERS
60ThrombosisFAERS: 2US FAERS
61TinnitusFAERS: 2
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
62TremorFAERS: 2SIDER
US FAERS
63Venous thrombosis limbFAERS: 2US FAERS
64Abdominal discomfortFAERS: 1
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
65Accidental exposure to productFAERS: 1US FAERS
66Acute respiratory failureFAERS: 1US FAERS
67Adverse eventFAERS: 1US FAERS
68AgranulocytosisFAERS: 1SIDER
US FAERS
69Anastomotic ulcerFAERS: 1US FAERS
70Blood glucose decreasedFAERS: 1OFFSIDES
US FAERS
71Blood glucose fluctuationFAERS: 1US FAERS
72Blood potassium decreasedFAERS: 1US FAERS
73Blood urine presentFAERS: 1US FAERS
74BradycardiaFAERS: 19202919CTD
SIDER
US FAERS
75BronchospasmFAERS: 1SIDER
US FAERS
76Cardiac ArrestFAERS: 1US FAERS
77CellulitisFAERS: 1OFFSIDES
US FAERS
78ChromaturiaFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
79Corneal ScarFAERS: 1US FAERS
80CryingFAERS: 1US FAERS
81DehydrationFAERS: 1US FAERS
82Disseminated Intravascular CoagulationFAERS: 1US FAERS
83Documented hypersensitivity to administered productFAERS: 1US FAERS
84Drug administered to patient of inappropriate ageFAERS: 1US FAERS
85Drug dose omissionFAERS: 1US FAERS
86Drug screen positiveFAERS: 1OFFSIDES
US FAERS
87DyspepsiaFAERS: 1SIDER
US FAERS
88DysphoniaFAERS: 1US FAERS
89DysuriaFAERS: 1OFFSIDES
SIDER
US FAERS
90Enlarged uvulaFAERS: 1US FAERS
91Eye InfectionFAERS: 1SIDER
US FAERS
92Eye inflammationFAERS: 1OFFSIDES
US FAERS
93Facial paralysisFAERS: 1US FAERS
94Feeling abnormalFAERS: 1SIDER
US FAERS
95FlatulenceFAERS: 1OFFSIDES
SIDER
US FAERS
96FlushingFAERS: 1SIDER
US FAERS
97HypophagiaFAERS: 1US FAERS
98HypoxiaFAERS: 1US FAERS
99Inappropriate affectFAERS: 1US FAERS
100Inappropriate schedule of product administrationFAERS: 1US FAERS
101InflammationFAERS: 118165188CTD
US FAERS
102InfluenzaFAERS: 1US FAERS
103Infusion site erythemaFAERS: 1US FAERS
104Infusion site painFAERS: 1US FAERS
105Infusion site pruritusFAERS: 1US FAERS
106Infusion site rashFAERS: 1US FAERS
107Injection site cellulitisFAERS: 1US FAERS
108Injection site infectionFAERS: 1US FAERS
109Injury associated with deviceFAERS: 1US FAERS
110Intercepted drug dispensing errorFAERS: 1US FAERS
111Intercepted drug prescribing errorFAERS: 1US FAERS
112IritisFAERS: 1SIDER
US FAERS
113Joint Range of Motion DecreasedFAERS: 1OFFSIDES
US FAERS
114Joint swellingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
115LacerationFAERS: 1OFFSIDES
US FAERS
116LaryngitisFAERS: 1US FAERS
117Ligament injuryFAERS: 1US FAERS
118LymphadenopathyFAERS: 1SIDER
US FAERS
119Medication ErrorFAERS: 1US FAERS
120Mouth swellingFAERS: 1US FAERS
121Multi-organ disorderFAERS: 1US FAERS
122Musculoskeletal chest painFAERS: 1US FAERS
123Musculoskeletal discomfortFAERS: 1OFFSIDES
SIDER
US FAERS
124No adverse eventFAERS: 1US FAERS
125Occupational exposure to productFAERS: 1US FAERS
126OliguriaFAERS: 1SIDER
US FAERS
127PapuleFAERS: 1US FAERS
128ParanoiaFAERS: 1SIDER
US FAERS
129PericarditisFAERS: 1US FAERS
130Post procedural complicationFAERS: 1OFFSIDES
US FAERS
131PresyncopeFAERS: 1US FAERS
132Procedural hypotensionFAERS: 1US FAERS
133Product depositFAERS: 1US FAERS
134Product dose omissionFAERS: 1US FAERS
135Product use issueFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
136Purpura FulminansFAERS: 1US FAERS
137QuadriplegiaFAERS: 1US FAERS
138Skin WrinklingFAERS: 1US FAERS
139Spinal column stenosisFAERS: 1US FAERS
140Status EpilepticusFAERS: 1US FAERS
141Streptococcus test positiveFAERS: 1US FAERS
142SwellingFAERS: 1SIDER
US FAERS
143SyncopeFAERS: 1SIDER
US FAERS
144Toxic Epidermal NecrolysisFAERS: 1SIDER
US FAERS
145VertigoFAERS: 1SIDER
US FAERS
146Visual ImpairmentFAERS: 1SIDER
US FAERS
147WheezingFAERS: 1SIDER
US FAERS
148Wrong patient received medicationFAERS: 1US FAERS
149Wrong technique in drug usage processFAERS: 1US FAERS
150Wrong technique in product usage processFAERS: 1US FAERS
151Abnormal visionSIDER
152AbuseOFFSIDES
153Acid refluxOFFSIDES
154ActinomycosisOFFSIDES
155Acute Chest SyndromeOFFSIDES
156Acute Coronary SyndromeSIDER
157Acute kidney injury

View details

1558096
8007038
8079033
8272928
8273901
8575131
8692635
9027269
9152303
12195419
 		CTD
158Acute prerenal failureOFFSIDES
159AdenocarcinomaOFFSIDES
160AgitationSIDER
161Alanine Aminotransferase IncreasedOFFSIDES
162Alcohol abuseOFFSIDES
163AlopeciaSIDER
164Altered state of consciousnessOFFSIDES
165AlveolitisOFFSIDES
166AmenorrheaOFFSIDES
167Anaphylactic shockSIDER
168Anaphylactoid ReactionSIDER
169AngerOFFSIDES
170AnhedoniaOFFSIDES
171Animal scratchOFFSIDES
172AnisocoriaOFFSIDES
173AnorexiaSIDER
174Arterial InjuryOFFSIDES
175ArthritisOFFSIDES
SIDER
176ArthropathyOFFSIDES
SIDER
177ArthroscopyOFFSIDES
178Aspartate Aminotransferase IncreasedSIDER
179AtelectasisOFFSIDES
180Atrial FlutterOFFSIDES
181Atrial tachycardiaOFFSIDES
182Atrioventricular BlockOFFSIDES
183Autonomic neuropathyOFFSIDES
184Basal Ganglia Diseases11869410CTD
185Basal cell carcinomaOFFSIDES
186Bipolar DisorderOFFSIDES
187Bipolar I disorderOFFSIDES
188Bladder painSIDER
189BlepharitisSIDER
190Blood GlucoseOFFSIDES
191Blood alkaline phosphatase increasedOFFSIDES
192Blood and lymphatic system disordersSIDER
193Blood bilirubin unconjugated increasedOFFSIDES
194Blood glucose abnormalOFFSIDES
195Blood triglycerides increasedOFFSIDES
196Blood urea increasedSIDER
197Bone density decreasedOFFSIDES
198Bone infarctionOFFSIDES
199Bone painOFFSIDES
200Brain scan abnormalOFFSIDES
201Breast CystOFFSIDES
202Breast FeedingSIDER
203BronchitisOFFSIDES
204BruxismOFFSIDES
205BursitisOFFSIDES
206Calcific deposits removalOFFSIDES
207CandiduriaOFFSIDES
208CataractSIDER
209Catheter sepsisOFFSIDES
210Cervical dysplasiaOFFSIDES
211ChillsSIDER
212Choking sensationOFFSIDES
213Chronic Obstructive Airway DiseaseOFFSIDES
214Chronic sinusitisOFFSIDES
215Coagulation factor increasedOFFSIDES
216ColitisOFFSIDES
SIDER
217Colon adenomaOFFSIDES
218Compression fractureOFFSIDES
219Compulsive shoppingOFFSIDES
220Conjunctival depositOFFSIDES
221ConjunctivitisSIDER
222ConstipationSIDER
223Conversion disorderOFFSIDES
224Corneal PerforationSIDER
225Corneal UlcerOFFSIDES
226Corneal erosionSIDER
227Corneal lesionSIDER
228Corneal thinningSIDER
229Creatinine increasedSIDER
230CystitisSIDER
231DeafnessSIDER
232DebridementOFFSIDES
233DemyelinationOFFSIDES
234Dental cariesOFFSIDES
235Depressed Level of ConsciousnessSIDER
236DermatitisSIDER
237DiabetesOFFSIDES
238Diabetes mellitus inadequate controlOFFSIDES
239Diabetic Autonomic NeuropathyOFFSIDES
240DiarrheaOFFSIDES
241DiplopiaSIDER
242Disturbance in sexual arousalSIDER
243DiverticulosisOFFSIDES
244DiverticulumOFFSIDES
245DrowsinessSIDER
246Drug Eruptions11792017CTD
247Drug withdrawal headacheOFFSIDES
248DysgeusiaOFFSIDES
SIDER
249DysmenorrheaOFFSIDES
250Dysthymic DisorderOFFSIDES
251DystoniaOFFSIDES
252EcchymosisSIDER
253Economic problemOFFSIDES
254Edema19459639CTD
255Electrocardiogram ST-T segment depressionOFFSIDES
256Emotional distressOFFSIDES
257Endodontic procedureOFFSIDES
258EndophthalmitisSIDER
259Engraftment syndromeOFFSIDES
260Enterocutaneous FistulaOFFSIDES
261EosinophiliaSIDER
262EpicondylitisOFFSIDES
263Epidermal necrosisSIDER
264EpistaxisCanada Vigilance: 1Canada Vigilance
SIDER
265EructationSIDER
266Erythema MultiformeSIDER
267Euphoric moodSIDER
268Exacerbation of asthmaSIDER
269Eye BurnsSIDER
270Febrile NeutropeniaOFFSIDES
271FibromyalgiaOFFSIDES
272Fistula repairOFFSIDES
273Flank PainSIDER
274Fluid overloadOFFSIDES
275FormicationOFFSIDES
276GamblingOFFSIDES
277Gamma-Glutamyltransferase IncreasedOFFSIDES
278GastroduodenitisOFFSIDES
279Gastrointestinal PainSIDER
280Gastrointestinal fullnessSIDER
281Gastrointestinal perforationSIDER
282General physical health deteriorationOFFSIDES
283GlaucomaSIDER
284GlossitisSIDER
285GranulocytosisOFFSIDES
286Hallucinations, mixedOFFSIDES
287Hearing Loss9105776CTD
288HeartburnSIDER
289Hematoma10100293CTD
290Hemorrhage8695075CTD
291Hepatic congestionOFFSIDES
292HepatitisOFFSIDES
SIDER
293HerniaSIDER
294HiccoughOFFSIDES
295HydronephrosisOFFSIDES
296Hyperalgesia16448827CTD
297Hyperkalemia8575131CTD
298HyperkinesiaSIDER
299HyperventilationCanada Vigilance: 1Canada Vigilance
300ImmobileOFFSIDES
301Impaired gastric emptyingOFFSIDES
302Incorrect drug administration rateOFFSIDES
303InfectionSIDER
304InfertilitySIDER
305Infusion site mobility decreasedOFFSIDES
306Injection site dermatitisOFFSIDES
307Intentional self-injuryOFFSIDES
308Intercostal neuralgiaOFFSIDES
309Intervertebral disc disorderOFFSIDES
310Intestinal ObstructionOFFSIDES
311Intestinal PerforationOFFSIDES
312Keratic precipitatesSIDER
313Kidney FailureOFFSIDES
314Kidney Papillary Necrosis8782036CTD
315KleptomaniaOFFSIDES
316Lacrimal structural disorderSIDER
317LacrimationSIDER
318Left Ventricular HypertrophyOFFSIDES
319Leukopenia neonatalOFFSIDES
320LeukopeniaSIDER
321Ligament ruptureOFFSIDES
322LightheadednessSIDER
323LymphomaOFFSIDES
324MalnutritionSIDER
325Mass excisionOFFSIDES
326Medical device complicationOFFSIDES
327Meniscus removalOFFSIDES
328Mental impairmentOFFSIDES
329Metabolic acidosisOFFSIDES
SIDER
330Metastases to abdominal cavityOFFSIDES
331Migraine Disorders8782036
11867972		CTD
332Muscle necrosisOFFSIDES
333Musculoskeletal stiffnessOFFSIDES
334Myocardial InfarctionSIDER
335Myocardial fibrosisOFFSIDES
336Nasal discomfortSIDER
337NasopharyngitisSIDER
338NephritisSIDER
339Nephrogenic Diabetes InsipidusOFFSIDES
340Nephrotic SyndromeSIDER
341Nerve Root CompressionOFFSIDES
342OnychalgiaOFFSIDES
343Open reduction of fractureOFFSIDES
344Oral Cavity FistulaOFFSIDES
345Oral painSIDER
346Oropharyngeal discomfortSIDER
347Oropharyngeal painOFFSIDES
SIDER
348OsteolysisOFFSIDES
349OsteomyelitisOFFSIDES
350OsteosclerosisOFFSIDES
351Pain, Postoperative

View details

1558096
7549168
8272928
8695075
8919832
9463202
11731754
12224377
16113981
16306736
19594851
 		CTD
352PallorSIDER
353PalpitationsCanada Vigilance: 1Canada Vigilance
SIDER
354Pancreatic PseudocystOFFSIDES
355PancreatitisSIDER
356PancytopeniaSIDER
357PanophthalmitisSIDER
358PapillomaOFFSIDES
359Paranoid reactionSIDER
360Peptic UlcerSIDER
361Pericardial effusionOFFSIDES
362PeritonitisOFFSIDES
363Personality ChangeOFFSIDES
364PhotophobiaSIDER
365Pneumatosis Cystoides IntestinalisOFFSIDES
366PneumothoraxOFFSIDES
367Polyarteritis Nodosa7594371CTD
368Polysubstance dependenceOFFSIDES
369PolyuriaSIDER
370Poor dental conditionOFFSIDES
371Post procedural discomfortOFFSIDES
372Post procedural dizzinessOFFSIDES
373PostmenopauseOFFSIDES
374Postoperative HemorrhageSIDER
375Postoperative wound complicationOFFSIDES
376Prescribed overdoseOFFSIDES
377Primary sequestrumOFFSIDES
378ProctocolitisSIDER
379Protein urine presentSIDER
380ProteinuriaSIDER
381Psychiatric symptomOFFSIDES
382Psychotic Disorders11869410CTD
383Pulmonary EmbolismSIDER
384Pulmonary HypertensionOFFSIDES
385Pulmonary arterial pressure increasedOFFSIDES
386Pulmonary congestionOFFSIDES
387PurpuraSIDER
388Purulent dischargeOFFSIDES
389PyelonephritisOFFSIDES
390Radicular painOFFSIDES
391RalesOFFSIDES
392RednessSIDER
393Reflex Sympathetic DystrophyOFFSIDES
394Renal Insufficiency8775277
10100293
17272643		CTD
395Renal tubular necrosisOFFSIDES
396Respiratory DepressionSIDER
397Respiratory FailureOFFSIDES
398Restrictive pulmonary diseaseOFFSIDES
399Retinal cystOFFSIDES
400Retrosternal painSIDER
401RhinalgiaSIDER
402RhinitisOFFSIDES
SIDER
403Right ventricular systolic pressure increasedOFFSIDES
404Salpingo-oophorectomyOFFSIDES
405Scotoma20656711CTD
406Sense of oppressionOFFSIDES
407SepsisSIDER
408Septic ShockOFFSIDES
409Serum urea increasedSIDER
410ShockSIDER
411Skin lacerationOFFSIDES
412Sore mouthSIDER
413SpondylolisthesisOFFSIDES
414SprainSIDER
415StarvationOFFSIDES
416Stevens-Johnson Syndrome25811541CTD
SIDER
417Stomach Diseases15102535CTD
418Stomach acheSIDER
419StomatitisSIDER
420Stomatocytes presentOFFSIDES
421StuporSIDER
422Substance Withdrawal Syndrome11976266
16448827		CTD
423Superficial ThrombophlebitisOFFSIDES
424SweatingSIDER
425Synovial CystOFFSIDES
426SynovitisOFFSIDES
427TendinitisOFFSIDES
428TenosynovitisOFFSIDES
429TensionSIDER
430ThirstSIDER
431Throat irritationSIDER
432ThrombocytopeniaSIDER
433Tooth ExtractionOFFSIDES
434Tooth InfectionOFFSIDES
435Tooth LossOFFSIDES
436TraumaSIDER
437Ulcerative stomatitisSIDER
438Ulcer18165188CTD
OFFSIDES
SIDER
439Unevaluable eventOFFSIDES
440Urinary RetentionSIDER
441Urine output increasedSIDER
442Urobilin urineOFFSIDES
443Uterine spasmOFFSIDES
444Vascular purpuraSIDER
445VasculitisSIDER
446Vasodilation procedureSIDER
447VasodilationSIDER
448Venous InjuryOFFSIDES
449Visual disturbanceOFFSIDES
SIDER
450Weaning failureOFFSIDES
451effusionOFFSIDES
452jaundiceSIDER
453kyphosisOFFSIDES
454nervous system disorderSIDER
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