MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Docusate sodium

(APSBXTVYXVQYAB-UHFFFAOYSA-M)

Structure

SMILES: CCCCC(COC(=O)CC(S(=O)(=O)[O-])C(=O)OCC(CCCC)CC)CC.[Na+]
Molecular Formula:: C20H37NaO7S
Molecular Weight:: 444.558
Log P:: 4.8903
Hydrogen Bond Acceptor:: 7
Hydrogen Bond Donor:: 0
TPSA:: 118.18
CAS Number(s):: 577-11-7

Synonym(s)

Docusate sodium

External Link(s)

PubChem Compound	23673837
ChEBI	4674
CHEMBL	CHEMBL1905872
KEGG	dr:D00305

Adverse Drug Event(s)

	Name	Number of Reports	Data Source
1	Drug ineffective	FAERS: 13 Canada Vigilance: 8	Canada Vigilance US FAERS
2	Constipation	FAERS: 8 Canada Vigilance: 1	Canada Vigilance US FAERS
3	Feeling abnormal	FAERS: 8	US FAERS
4	Asthenia	FAERS: 6	OFFSIDES US FAERS
5	Overdose	FAERS: 6	US FAERS
6	Abdominal Pain	FAERS: 5	OFFSIDES US FAERS
7	Intestinal Obstruction	FAERS: 4	US FAERS
8	Medication Error	FAERS: 4	US FAERS
9	Nausea	FAERS: 4 Canada Vigilance: 1	Canada Vigilance OFFSIDES US FAERS
10	Dehydration	FAERS: 3	OFFSIDES US FAERS
11	Drug dispensing error	FAERS: 3	US FAERS
12	Dysgeusia	FAERS: 3	US FAERS
13	Malaise	FAERS: 3	US FAERS
14	Palpitations	FAERS: 3	US FAERS
15	Product quality issue	FAERS: 3	US FAERS
16	Stress	FAERS: 3	US FAERS
17	Unevaluable event	FAERS: 3	US FAERS
18	Acute prerenal failure	FAERS: 2	OFFSIDES US FAERS
19	Amnesia	FAERS: 2	OFFSIDES US FAERS
20	Angina Pectoris	FAERS: 2	US FAERS
21	Burkholderia test positive	FAERS: 2	US FAERS
22	Chest discomfort	FAERS: 2	US FAERS
23	Chills	FAERS: 2	US FAERS
24	Disability	FAERS: 2	US FAERS
25	Drug Dependence	FAERS: 2	US FAERS
26	Fluid imbalance	FAERS: 2	US FAERS
27	Foreign body in respiratory tract	FAERS: 2	US FAERS
28	Hypersensitivity	FAERS: 2	US FAERS
29	Inappropriate schedule of drug administration	FAERS: 2	US FAERS
30	Memory impairment	FAERS: 2	US FAERS
31	Product physical issue	FAERS: 2	US FAERS
32	Pulmonary congestion	FAERS: 2	US FAERS
33	Rectal tenesmus	FAERS: 2	US FAERS
34	Respiratory distress	FAERS: 2	US FAERS
35	Syncope	FAERS: 2	US FAERS
36	Vomiting	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
37	Weight decreased	FAERS: 2	US FAERS
38	Wheezing	FAERS: 2	US FAERS
39	Abasia	FAERS: 1	US FAERS
40	Abdominal adhesions	FAERS: 1	OFFSIDES US FAERS
41	Abscess	FAERS: 1	OFFSIDES US FAERS
42	Alopecia	FAERS: 1	US FAERS
43	Anaphylactic shock	FAERS: 1	US FAERS
44	Anger	FAERS: 1	US FAERS
45	Anorectal discomfort	FAERS: 1	US FAERS
46	Bladder spasm	FAERS: 1	US FAERS
47	Blood creatinine abnormal	FAERS: 1	US FAERS
48	Blood glucose decreased	FAERS: 1	OFFSIDES US FAERS
49	Blood urine present	FAERS: 1	US FAERS
50	Body temperature fluctuation	FAERS: 1	US FAERS
51	Bone pain	FAERS: 1	US FAERS
52	Cerebrovascular accident	FAERS: 1	US FAERS
53	Cervix carcinoma	FAERS: 1	US FAERS
54	Choking	FAERS: 1	US FAERS
55	Chronic left ventricular failure	FAERS: 1	US FAERS
56	Dementia	FAERS: 1	US FAERS
57	Dizziness	FAERS: 1	OFFSIDES US FAERS
58	Drug abuse	FAERS: 1	US FAERS
59	Drug dose omission	FAERS: 1	US FAERS
60	Dyschezia	FAERS: 1	US FAERS
61	Epilepsy	FAERS: 1	US FAERS
62	Erythema	FAERS: 1	US FAERS
63	Expired product administered	FAERS: 1	US FAERS
64	Flatulence	FAERS: 1	US FAERS
65	Foreign body aspiration	FAERS: 1	US FAERS
66	Full blood count abnormal	FAERS: 1	US FAERS
67	Full blood count decreased	FAERS: 1	US FAERS
68	Gastrointestinal motility disorder	FAERS: 1	US FAERS
69	Gastrointestinal perforation	FAERS: 1	US FAERS
70	Headache	FAERS: 1	US FAERS
71	Hernia pain	FAERS: 1	US FAERS
72	Hernia	FAERS: 1	OFFSIDES US FAERS
73	Hospice Care	FAERS: 1	US FAERS
74	Hypertrophic Cardiomyopathy	FAERS: 1	US FAERS
75	Incorrect route of drug administration	FAERS: 1	US FAERS
76	Intestinal stent insertion	FAERS: 1	US FAERS
77	Joint swelling	FAERS: 1	US FAERS
78	Macular degeneration	FAERS: 1	US FAERS
79	Medication residue present	FAERS: 1	US FAERS
80	Moaning	FAERS: 1	US FAERS
81	Myocardial Infarction	FAERS: 1	US FAERS
82	Nephrolithiasis	FAERS: 1	OFFSIDES US FAERS
83	Oliguria	FAERS: 1	US FAERS
84	Oropharyngeal pain	FAERS: 1	OFFSIDES US FAERS
85	Pain	FAERS: 1 Canada Vigilance: 1	Canada Vigilance OFFSIDES US FAERS
86	Pharmaceutical product complaint	FAERS: 1	US FAERS
87	Product adhesion issue	FAERS: 1	US FAERS
88	Product commingling	FAERS: 1	US FAERS
89	Product contamination microbial	FAERS: 1	US FAERS
90	Product contamination physical	FAERS: 1	US FAERS
91	Product counterfeit	FAERS: 1	US FAERS
92	Product label issue	FAERS: 1	US FAERS
93	Product leakage	FAERS: 1	US FAERS
94	Product size issue	FAERS: 1	US FAERS
95	Product substitution issue	FAERS: 1	US FAERS
96	Product taste abnormal	FAERS: 1	US FAERS
97	Product use issue	FAERS: 1	US FAERS
98	Sputum culture positive	FAERS: 1	US FAERS
99	Throat irritation	FAERS: 1	US FAERS
100	Tremor	FAERS: 1	US FAERS
101	Urinary Incontinence	FAERS: 1	US FAERS
102	Urticaria	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
103	Visual Impairment	FAERS: 1	US FAERS
104	Wrong technique in drug usage process	FAERS: 1	US FAERS
105	Abdominal Abscess		OFFSIDES
106	Abdominal discomfort		OFFSIDES
107	Abdominal mass		OFFSIDES
108	Abuse		OFFSIDES
109	Acanthosis		OFFSIDES
110	Acid reflux		OFFSIDES
111	Acidosis		OFFSIDES
112	Acquired mitochondrial DNA mutation		OFFSIDES
113	Actinomycosis		OFFSIDES
114	Activities of daily living impaired		OFFSIDES
115	Acute respiratory failure		OFFSIDES
116	Adverse event		OFFSIDES
117	Alveolitis		OFFSIDES
118	Amblyopia		OFFSIDES
119	Anal Fissure		OFFSIDES
120	Androgens decreased		OFFSIDES
121	Anhedonia		OFFSIDES
122	Anhidrosis		OFFSIDES
123	Anticonvulsant drug level below therapeutic		OFFSIDES
124	Anxiety		OFFSIDES
125	Aphagia		OFFSIDES
126	Appendicitis		OFFSIDES
127	Application site urticaria		OFFSIDES
128	Arteriosclerosis		OFFSIDES
129	Arthritis		OFFSIDES
130	Arthroscopy		OFFSIDES
131	Ascites		OFFSIDES
132	Aspiration Pneumonia		OFFSIDES
133	Astigmatism		OFFSIDES
134	Ataxia		OFFSIDES
135	Atrial Flutter		OFFSIDES
136	Aura		OFFSIDES
137	Bacterial disease carrier		OFFSIDES
138	Band neutrophil percentage increased		OFFSIDES
139	Basal cell carcinoma		OFFSIDES
140	Belligerence		OFFSIDES
141	Biopsy breast abnormal		OFFSIDES
142	Blood 1,25-dihydroxycholecalciferol decreased		OFFSIDES
143	Blood Glucose		OFFSIDES
144	Blood amylase increased		OFFSIDES
145	Blood bicarbonate		OFFSIDES
146	Blood cholesterol		OFFSIDES
147	Blood creatinine increased		OFFSIDES
148	Blood electrolytes decreased		OFFSIDES
149	Blood immunoglobulin G increased		OFFSIDES
150	Blood magnesium increased		OFFSIDES
151	Blood phosphorus decreased		OFFSIDES
152	Blood potassium decreased		OFFSIDES
153	Blurred vision		OFFSIDES
154	Bone density decreased		OFFSIDES
155	Bone erosion		OFFSIDES
156	Bone fragmentation		OFFSIDES
157	Bone lesion		OFFSIDES
158	Brain natriuretic peptide increased		OFFSIDES
159	Bronchitis		OFFSIDES
160	Bruxism		OFFSIDES
161	Burning sensation		OFFSIDES
162	CD4 Lymphocytes Decreased		OFFSIDES
163	Catheter related infection		OFFSIDES
164	Catheter site erythema		OFFSIDES
165	Cellulitis		OFFSIDES
166	Chest Pain		OFFSIDES
167	Choking sensation		OFFSIDES
168	Chromaturia		OFFSIDES
169	Circumstance or information capable of leading to medication error		OFFSIDES
170	Compulsive shopping		OFFSIDES
171	Confabulation		OFFSIDES
172	Congenital pulmonary hypertension		OFFSIDES
173	Congenital tricuspid valve incompetence		OFFSIDES
174	Contraindicated product administered	Canada Vigilance: 1	Canada Vigilance
175	Coronary artery insufficiency		OFFSIDES
176	Cyst		OFFSIDES
177	Cytomegalovirus chorioretinitis		OFFSIDES
178	Decreased Libido		OFFSIDES
179	Demyelination		OFFSIDES
180	Dental Fistula		OFFSIDES
181	Dental caries		OFFSIDES
182	Dental prosthesis user		OFFSIDES
183	Dependent Personality Disorder		OFFSIDES
184	Depression suicidal		OFFSIDES
185	Device Failure		OFFSIDES
186	Diabetes		OFFSIDES
187	Diabetes mellitus inadequate control		OFFSIDES
188	Diabetic Foot		OFFSIDES
189	Diaphragmatic Hernia		OFFSIDES
190	Diarrhea		OFFSIDES
191	Diastolic dysfunction		OFFSIDES
192	Disease Progression		OFFSIDES
193	Distal intestinal obstruction syndrome		OFFSIDES
194	Diverticular perforation		OFFSIDES
195	Diverticulum		OFFSIDES
196	Drowsiness		OFFSIDES
197	Drug addict		OFFSIDES
198	Drug administered at inappropriate site		OFFSIDES
199	Drug effect delayed		OFFSIDES
200	Drug screen negative		OFFSIDES
201	Drug toxicity		OFFSIDES
202	Dry skin		OFFSIDES
203	Dysmorphism		OFFSIDES
204	Dysthymic Disorder		OFFSIDES
205	Dysuria		OFFSIDES
206	Eczema		OFFSIDES
207	Electrocardiogram ST segment abnormal		OFFSIDES
208	Electrocardiogram ST-T change		OFFSIDES
209	Emotional distress		OFFSIDES
210	Endodontic procedure		OFFSIDES
211	Enterobacter pneumonia		OFFSIDES
212	Enterococcal infection		OFFSIDES
213	Enterocutaneous Fistula		OFFSIDES
214	Enzyme abnormality		OFFSIDES
215	Epidural Abscess		OFFSIDES
216	Erosive gastritis		OFFSIDES
217	Esophageal Stenosis		OFFSIDES
218	Excoriation		OFFSIDES
219	Eye inflammation		OFFSIDES
220	Eyelid Diseases		OFFSIDES
221	Failure of implant		OFFSIDES
222	Failure to Thrive		OFFSIDES
223	Fatigue		OFFSIDES
224	Febrile Neutropenia		OFFSIDES
225	Flank Pain		OFFSIDES
226	Flight of ideas		OFFSIDES
227	Fluid overload		OFFSIDES
228	Formication		OFFSIDES
229	Galactorrhea		OFFSIDES
230	Gambling		OFFSIDES
231	Gangrene		OFFSIDES
232	Gastric Bypass		OFFSIDES
233	Gastrointestinal ulcer		OFFSIDES
234	Gaze palsy		OFFSIDES
235	Genital Herpes		OFFSIDES
236	Gingival graft		OFFSIDES
237	Gout		OFFSIDES
238	Growth of eyelashes		OFFSIDES
239	Heparin-induced thrombocytopenia		OFFSIDES
240	Hepatic Infarction		OFFSIDES
241	Hepatic necrosis		OFFSIDES
242	Hepatosplenomegaly		OFFSIDES
243	Hiccough		OFFSIDES
244	Hydronephrosis		OFFSIDES
245	Hypercreatininaemia		OFFSIDES
246	Hyperkeratosis		OFFSIDES
247	Hyperpigmentation		OFFSIDES
248	Hypertensive emergency		OFFSIDES
249	Hypophagia		OFFSIDES
250	Hypoxia		OFFSIDES
251	Infection		OFFSIDES
252	Infusion Site Extravasation		OFFSIDES
253	Injection site injury		OFFSIDES
254	Insulin-requiring type 2 diabetes mellitus		OFFSIDES
255	Intention tremor		OFFSIDES
256	Intestinal resection		OFFSIDES
257	Intestinal stoma complication		OFFSIDES
258	Intraocular inflammation		OFFSIDES
259	Intraocular pressure test		OFFSIDES
260	Intussusception		OFFSIDES
261	Joint sprain		OFFSIDES
262	Kidney Failure		OFFSIDES
263	Left Ventricular Hypertrophy		OFFSIDES
264	Left atrial dilatation		OFFSIDES
265	Legionella		OFFSIDES
266	Lesion excision		OFFSIDES
267	Lethargy		OFFSIDES
268	Leukopenia neonatal		OFFSIDES
269	Lipase		OFFSIDES
270	Liver Abscess		OFFSIDES
271	Liver transplant rejection		OFFSIDES
272	Loose tooth		OFFSIDES
273	Lung Injury		OFFSIDES
274	Lymphocyte count decreased		OFFSIDES
275	Malignant neoplasm progression		OFFSIDES
276	Medical device removal		OFFSIDES
277	Mental status changes		OFFSIDES
278	Metabolic acidosis		OFFSIDES
279	Metastatic Renal Cell Carcinoma		OFFSIDES
280	Metatarsalgia		OFFSIDES
281	Multiple Myeloma		OFFSIDES
282	Multiple Sclerosis		OFFSIDES
283	Multiple sclerosis relapse		OFFSIDES
284	Muscle Weakness		OFFSIDES
285	Muscle necrosis		OFFSIDES
286	Musculoskeletal Pain		OFFSIDES
287	Musculoskeletal discomfort		OFFSIDES
288	Musculoskeletal stiffness		OFFSIDES
289	Nephrogenic Fibrosing Dermopathy		OFFSIDES
290	Neurodermatitis		OFFSIDES
291	Neuroleptic Malignant Syndrome		OFFSIDES
292	Neutrophil count decreased		OFFSIDES
293	Nodule on extremity		OFFSIDES
294	Noonan Syndrome		OFFSIDES
295	Obstruction		OFFSIDES
296	Optic Disc Edema		OFFSIDES
297	Optic Neuritis		OFFSIDES
298	Oral Cavity Fistula		OFFSIDES
299	Oral infection		OFFSIDES
300	Oral mucosa atrophy		OFFSIDES
301	Oral polypectomy		OFFSIDES
302	Osteolysis		OFFSIDES
303	Osteomyelitis		OFFSIDES
304	Osteopenia		OFFSIDES
305	Pancreatitis		OFFSIDES
306	Paranoia		OFFSIDES
307	Patellofemoral Pain Syndrome		OFFSIDES
308	Perirectal abscess		OFFSIDES
309	Peroneal nerve injury		OFFSIDES
310	Pinguecula		OFFSIDES
311	Plasmacytoma		OFFSIDES
312	Plasmacytosis		OFFSIDES
313	Polyuria		OFFSIDES
314	Portal Vein Thrombosis		OFFSIDES
315	Post procedural cellulitis		OFFSIDES
316	Post procedural complication		OFFSIDES
317	Postmenopausal bleeding		OFFSIDES
318	Postural Orthostatic Tachycardia Syndrome		OFFSIDES
319	Presbyopia		OFFSIDES
320	Primary sequestrum		OFFSIDES
321	Propofol Infusion Syndrome		OFFSIDES
322	Pruritus	Canada Vigilance: 1	Canada Vigilance
323	Pulmonary Hypertension		OFFSIDES
324	Pulmonary Valve Stenosis		OFFSIDES
325	Pulmonary malformation		OFFSIDES
326	Purulent discharge		OFFSIDES
327	Rash erythematous	Canada Vigilance: 1	Canada Vigilance
328	Red cell distribution width decreased		OFFSIDES
329	Reflux gastritis		OFFSIDES
330	Reflux laryngitis		OFFSIDES
331	Regurgitation		OFFSIDES
332	Renal tubular necrosis		OFFSIDES
333	Respiratory Failure		OFFSIDES
334	Sarcoidosis		OFFSIDES
335	Schizoaffective Disorder		OFFSIDES
336	Schizophrenia		OFFSIDES
337	Septic Shock		OFFSIDES
338	Sick Sinus Syndrome		OFFSIDES
339	Sinusitis		OFFSIDES
340	Skin Induration		OFFSIDES
341	Skin laceration		OFFSIDES
342	Skin neoplasm excision		OFFSIDES
343	Spinal column stenosis		OFFSIDES
344	Splenic Infarction		OFFSIDES
345	Stem cell transplant		OFFSIDES
346	Subcutaneous Abscess		OFFSIDES
347	Supraventricular tachycardia		OFFSIDES
348	Sweat gland infection		OFFSIDES
349	Synovial Cyst		OFFSIDES
350	Temperature regulation disorder		OFFSIDES
351	Tooth Extraction		OFFSIDES
352	Tooth Infection		OFFSIDES
353	Tooth Loss		OFFSIDES
354	Tooth repair		OFFSIDES
355	Troponin increased		OFFSIDES
356	Ultrasound breast abnormal		OFFSIDES
357	Unresponsive to stimuli		OFFSIDES
358	Urinary tract infection staphylococcal		OFFSIDES
359	VIIth nerve paralysis		OFFSIDES
360	Vein wall hypertrophy		OFFSIDES
361	Vitreous degeneration		OFFSIDES
362	Vulvovaginal pruritus		OFFSIDES
363	Weight Gain		OFFSIDES
364	Wound Infection		OFFSIDES
365	Wound dehiscence		OFFSIDES
366	fibroma		OFFSIDES

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120235