MetaADEDB 2.0 @ LMMD
Micafungin
(PIEUQSKUWLMALL-YABMTYFHSA-N)
Structure
SMILES
CCCCCOc1ccc(cc1)c1onc(c1)c1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@H](CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC1=O)[C@H](O)C)C[C@@H](C2)O)[C@@H]([C@H](c1ccc(c(c1)OS(=O)(=O)O)O)O)O)[C@@H](CC(=O)N)O)C
Type(s)
Approved; Investigational
ATC code(s)
J02AX05
Molecular Formula:
C56H71N9O23S
Molecular Weight:
1270.270
Log P:
-0.5390
Hydrogen Bond Acceptor:
32
Hydrogen Bond Donor:
16
TPSA:
518.52
CAS Number(s):
235114-32-6
Synonym(s)
1.
Micafungin
2.
FK 463
3.
FK-463
4.
FK463
5.
Micafungin Sodium
6.
Mycamine
External Link(s)
MeSHD000077551
PubChem Compound477468
ChEBI600520
CHEMBLCHEMBL457547
DrugBankDB01141
KEGGcpd:C15819
dr:D02465
dr:D08218
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Product use issueFAERS: 84US FAERS
2Drug ineffectiveFAERS: 58US FAERS
3Septic ShockFAERS: 23OFFSIDES
US FAERS
4Blood creatinine increasedFAERS: 15US FAERS
5Incorrect product storageFAERS: 14US FAERS
6SepsisFAERS: 14US FAERS
7InfectionFAERS: 13US FAERS
8Aspartate Aminotransferase IncreasedFAERS: 12US FAERS
9Alanine Aminotransferase IncreasedFAERS: 10OFFSIDES
US FAERS
10Drug resistanceFAERS: 10OFFSIDES
US FAERS
11Intentional product misuseFAERS: 10US FAERS
12Respiratory FailureFAERS: 10OFFSIDES
US FAERS
13treatment failureFAERS: 10US FAERS
14OverdoseFAERS: 9US FAERS
15Bronchopulmonary AspergillosisFAERS: 8US FAERS
16PneumoniaFAERS: 819148589CTD
US FAERS
17Product quality issueFAERS: 8US FAERS
18VomitingFAERS: 8US FAERS
19CandidiasisFAERS: 720606829CTD
US FAERS
20Cardiac ArrestFAERS: 7US FAERS
21Product storage errorFAERS: 7US FAERS
22Abdominal PainFAERS: 6US FAERS
23Candida sepsisFAERS: 6US FAERS
24NeutropeniaFAERS: 6US FAERS
25PalpitationsFAERS: 6US FAERS
26Chest discomfortFAERS: 5US FAERS
27HypersensitivityFAERS: 5US FAERS
28No adverse eventFAERS: 5US FAERS
29PancreatitisFAERS: 5US FAERS
30PeritonitisFAERS: 5US FAERS
31Atrial FibrillationFAERS: 4US FAERS
32Device related infectionFAERS: 4US FAERS
33LeukopeniaFAERS: 4US FAERS
34NauseaFAERS: 419148589CTD
US FAERS
35Product preparation errorFAERS: 4US FAERS
36Sinus bradycardiaFAERS: 4US FAERS
37Trichosporon infectionFAERS: 4OFFSIDES
US FAERS
38Wrong technique in product usage processFAERS: 4US FAERS
39Abdominal wound dehiscenceFAERS: 3US FAERS
40AgranulocytosisFAERS: 3US FAERS
41Altered state of consciousnessFAERS: 3US FAERS
42Anaphylactic shockFAERS: 3US FAERS
43AspergillosisFAERS: 3OFFSIDES
US FAERS
44Blood potassium decreasedFAERS: 3OFFSIDES
US FAERS
45Capillary Leak SyndromeFAERS: 3US FAERS
46ChillsFAERS: 3US FAERS
47CholestasisFAERS: 319325554CTD
US FAERS
48Disease ProgressionFAERS: 3OFFSIDES
US FAERS
49Disseminated Intravascular CoagulationFAERS: 3OFFSIDES
US FAERS
50DizzinessFAERS: 3US FAERS
51Drug ineffective for unapproved indicationFAERS: 3US FAERS
52EcchymosisFAERS: 3US FAERS
53Gamma-Glutamyltransferase IncreasedFAERS: 3US FAERS
54HypotensionFAERS: 319148589CTD
US FAERS
55HypoxiaFAERS: 3OFFSIDES
US FAERS
56Injection site extravasationFAERS: 3US FAERS
57Intentional product use issueFAERS: 3US FAERS
58Liver transplant rejectionFAERS: 3US FAERS
59MucormycosisFAERS: 3OFFSIDES
US FAERS
60PhlebitisFAERS: 3US FAERS
61Product use in unapproved indicationFAERS: 3US FAERS
62ThrombosisFAERS: 3US FAERS
63Unresponsive to stimuliFAERS: 3US FAERS
64White blood cell count decreasedFAERS: 3US FAERS
65Accidental exposure to productFAERS: 2US FAERS
66Acute respiratory failureFAERS: 2US FAERS
67Bacillus infectionFAERS: 2US FAERS
68Blood alkaline phosphatase increasedFAERS: 2US FAERS
69Blood urea increasedFAERS: 2US FAERS
70Candida test positiveFAERS: 2US FAERS
71CardiomegalyFAERS: 2US FAERS
72Cerebrovascular accidentFAERS: 2US FAERS
73Chest PainFAERS: 2US FAERS
74ChromaturiaFAERS: 2US FAERS
75CyanosisFAERS: 2OFFSIDES
US FAERS
76DeliriumFAERS: 2US FAERS
77Disease recurrenceFAERS: 2OFFSIDES
US FAERS
78DyspepsiaFAERS: 2US FAERS
79ErythemaFAERS: 2US FAERS
80ExtravasationFAERS: 2US FAERS
81Febrile bone marrow aplasiaFAERS: 2US FAERS
82Fluid overloadFAERS: 2US FAERS
83General physical health deteriorationFAERS: 2US FAERS
84Graft infectionFAERS: 2OFFSIDES
US FAERS
85HepatitisFAERS: 2US FAERS
86HepatotoxicityFAERS: 2US FAERS
87HydrocephalusFAERS: 2US FAERS
88Hypoglossal nerve paralysisFAERS: 2US FAERS
89Incorrect storage of drugFAERS: 2US FAERS
90Klebsiella sepsisFAERS: 2US FAERS
91Large intestine perforationFAERS: 2US FAERS
92MediastinitisFAERS: 2US FAERS
93Metabolic alkalosisFAERS: 2US FAERS
94Myocardial InfarctionFAERS: 2US FAERS
95Neutrophil count decreasedFAERS: 2US FAERS
96Oropharyngeal painFAERS: 2US FAERS
97OsteolysisFAERS: 2US FAERS
98PainFAERS: 2US FAERS
99Pericardial effusionFAERS: 2US FAERS
100PetechiaeFAERS: 2US FAERS
101PneumothoraxFAERS: 2US FAERS
102Prescribed overdoseFAERS: 2US FAERS
103Productive CoughFAERS: 2US FAERS
104Pseudomonal sepsisFAERS: 2US FAERS
105RalesFAERS: 2US FAERS
106Respiratory distressFAERS: 2US FAERS
107Skin necrosisFAERS: 2US FAERS
108SomnolenceFAERS: 2US FAERS
109Stevens-Johnson SyndromeFAERS: 225811541CTD
US FAERS
110TachycardiaFAERS: 2US FAERS
111ThrombocytopeniaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
112Transaminases increasedFAERS: 2US FAERS
113TremorFAERS: 2US FAERS
114Urinary tract infectionFAERS: 2US FAERS
115UrticariaFAERS: 2US FAERS
116VasculitisFAERS: 2US FAERS
117Venous ThrombosisFAERS: 2US FAERS
118Vocal Cord ParalysisFAERS: 2US FAERS
119jaundiceFAERS: 2US FAERS
120nervous system disorderFAERS: 2US FAERS
121Abdominal discomfortFAERS: 1US FAERS
122AcidosisFAERS: 1OFFSIDES
US FAERS
123Acute Coronary SyndromeFAERS: 1US FAERS
124Administration site extravasationFAERS: 1US FAERS
125Alanine aminotransferase decreasedFAERS: 1US FAERS
126AlkalosisFAERS: 1US FAERS
127AngioedemaFAERS: 1US FAERS
128Aortic RuptureFAERS: 1US FAERS
129AphasiaFAERS: 1US FAERS
130ArthralgiaFAERS: 1US FAERS
131AsphyxiaFAERS: 1US FAERS
132AstheniaFAERS: 1US FAERS
133AsthmaFAERS: 1US FAERS
134Back PainFAERS: 1US FAERS
135Blood albumin decreasedFAERS: 1OFFSIDES
US FAERS
136Blood calcitonin increasedFAERS: 1US FAERS
137Blood creatine increasedFAERS: 1OFFSIDES
US FAERS
138Blood fibrinogen decreasedFAERS: 1US FAERS
139Blood glucose increasedFAERS: 1US FAERS
140Blood lactate dehydrogenase increasedFAERS: 1US FAERS
141Blood potassium increasedFAERS: 1US FAERS
142Blood pressure fluctuationFAERS: 1OFFSIDES
US FAERS
143Blood sodium increasedFAERS: 1OFFSIDES
US FAERS
144Blood urea abnormalFAERS: 1US FAERS
145BradycardiaFAERS: 1US FAERS
146Bronchopulmonary DysplasiaFAERS: 1US FAERS
147BronchospasmFAERS: 1US FAERS
148Bulbar palsyFAERS: 1US FAERS
149Candida pneumoniaFAERS: 1US FAERS
150Cerebral InfarctionFAERS: 1US FAERS
151Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
152Citrobacter infectionFAERS: 1US FAERS
153Clostridium difficile colitisFAERS: 1US FAERS
154Concomitant disease progressionFAERS: 1OFFSIDES
US FAERS
155Conjunctival pallorFAERS: 1US FAERS
156ConstipationFAERS: 1US FAERS
157Culture positiveFAERS: 1OFFSIDES
US FAERS
158DeafnessFAERS: 1US FAERS
159Depressed Level of ConsciousnessFAERS: 1US FAERS
160Depressed moodFAERS: 1US FAERS
161Diaphragmatic HerniaFAERS: 1US FAERS
162Drug administration errorFAERS: 1US FAERS
163Drug dispensing errorFAERS: 1US FAERS
164Drug prescribing errorFAERS: 1US FAERS
165DysphoniaFAERS: 1US FAERS
166Electrolyte imbalanceFAERS: 1US FAERS
167End stage AIDSFAERS: 1US FAERS
168EndophthalmitisFAERS: 1US FAERS
169Engraftment syndromeFAERS: 1US FAERS
170Enterococcal sepsisFAERS: 1US FAERS
171Expired product administeredFAERS: 1US FAERS
172Febrile NeutropeniaFAERS: 1OFFSIDES
US FAERS
173Feeling ColdFAERS: 1US FAERS
174Feeling abnormalFAERS: 1US FAERS
175Fistula of small intestineFAERS: 1US FAERS
176Fungal test positiveFAERS: 1US FAERS
177Gastrointestinal hypermotilityFAERS: 1US FAERS
178Gastrointestinal perforationFAERS: 1US FAERS
179Graft versus host disease in skinFAERS: 1US FAERS
180Grip strength decreasedFAERS: 1US FAERS
181HeadacheFAERS: 119148589CTD
US FAERS
182Hepatic EncephalopathyFAERS: 1US FAERS
183Hepatic candidiasisFAERS: 1US FAERS
184Hepatitis CFAERS: 1US FAERS
185HepatomegalyFAERS: 1US FAERS
186Histiocytosis haematophagicFAERS: 1US FAERS
187HyperpyrexiaFAERS: 1US FAERS
188IleusFAERS: 1US FAERS
189Incorrect dose administeredFAERS: 1US FAERS
190Incorrect drug administration rateFAERS: 1US FAERS
191Infection reactivationFAERS: 1US FAERS
192Infectious disease carrierFAERS: 1US FAERS
193Infectious peritonitisFAERS: 1US FAERS
194Intercepted medication errorFAERS: 1US FAERS
195Intestinal ObstructionFAERS: 1US FAERS
196Intestinal PerforationFAERS: 1US FAERS
197KetosisFAERS: 1US FAERS
198Klebsiella test positiveFAERS: 1US FAERS
199Ligament ruptureFAERS: 1US FAERS
200Liquid product physical issueFAERS: 1US FAERS
201Lung transplant rejectionFAERS: 1US FAERS
202LymphadenopathyFAERS: 1US FAERS
203Malignant neoplasm progressionFAERS: 1US FAERS
204MalnutritionFAERS: 1US FAERS
205Medication ErrorFAERS: 1US FAERS
206Mood swingsFAERS: 1US FAERS
207Myoglobin blood increasedFAERS: 1US FAERS
208Nephrogenic Diabetes InsipidusFAERS: 1OFFSIDES
US FAERS
209Neutropenic sepsisFAERS: 1US FAERS
210Night sweatsFAERS: 1US FAERS
211Non-cardiac chest painFAERS: 1US FAERS
212Optic NeuritisFAERS: 1US FAERS
213Oral candidiasisFAERS: 1US FAERS
214Oral painFAERS: 1US FAERS
215Oropharyngeal candidiasisFAERS: 1US FAERS
216PallorFAERS: 1US FAERS
217Pancreatic carcinomaFAERS: 1US FAERS
218PancytopeniaFAERS: 1US FAERS
219PericarditisFAERS: 1US FAERS
220Pneumocystis jiroveci pneumoniaFAERS: 1OFFSIDES
US FAERS
221Poor quality product administeredFAERS: 1US FAERS
222Postoperative respiratory failureFAERS: 1US FAERS
223Prescription form tamperingFAERS: 1US FAERS
224Product label issueFAERS: 1US FAERS
225Product preparation issueFAERS: 1US FAERS
226PruritusFAERS: 1US FAERS
227Pulmonary EmbolismFAERS: 1US FAERS
228Pulmonary congestionFAERS: 1US FAERS
229RegurgitationFAERS: 1US FAERS
230Respiratory arrestFAERS: 1US FAERS
231RhabdomyolysisFAERS: 1US FAERS
232Rhinovirus infectionFAERS: 1US FAERS
233Skeletal muscle enzymesFAERS: 1US FAERS
234Skin lesionFAERS: 1US FAERS
235StomatitisFAERS: 1US FAERS
236StridorFAERS: 1US FAERS
237Subcutaneous AbscessFAERS: 1US FAERS
238Sudden Cardiac DeathFAERS: 1US FAERS
239SyncopeFAERS: 1US FAERS
240Tendon discomfortFAERS: 1US FAERS
241Therapeutic response unexpectedFAERS: 1US FAERS
242Therapy non-responderFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
243Throat irritationFAERS: 1US FAERS
244Urinary RetentionFAERS: 1US FAERS
245Vascular graft complicationFAERS: 1US FAERS
246Venoocclusive diseaseFAERS: 1US FAERS
247Wound ComplicationFAERS: 1US FAERS
248Wrong drug administeredFAERS: 1US FAERS
249ZygomycosisFAERS: 1US FAERS
250pseudomembranous colitisFAERS: 1US FAERS
251Acute graft versus host disease in liverOFFSIDES
252Acute kidney injury19148589CTD
253AlopeciaOFFSIDES
254Anticonvulsant drug level below therapeuticOFFSIDES
255Antithrombin III decreasedOFFSIDES
256Bilirubin conjugated increasedOFFSIDES
257Bladder NeoplasmOFFSIDES
258Blood beta-D-glucan increasedOFFSIDES
259Bronchoalveolar LavageOFFSIDES
260CalcinosisOFFSIDES
261Candidemia19325554
20606829		CTD
262Cardiac TamponadeOFFSIDES
263Catheter sepsisOFFSIDES
264Catheter site painOFFSIDES
265Central line infectionOFFSIDES
266Chemical and Drug Induced Liver Injury19148589
19325554		CTD
267Chemotherapeutic drug level increasedOFFSIDES
268Concomitant disease aggravatedOFFSIDES
269ConfabulationOFFSIDES
270Corneal thinningOFFSIDES
271Cytomegalovirus chorioretinitisOFFSIDES
272Delayed engraftmentOFFSIDES
273Dermatomycoses18608918CTD
274DiabetesOFFSIDES
275Disease complicationOFFSIDES
276Drug level below therapeuticOFFSIDES
277Ejection Fraction DecreasedOFFSIDES
278Enterococcal infectionOFFSIDES
279EnterocolitisOFFSIDES
280Enterocutaneous FistulaOFFSIDES
281Esophageal StenosisOFFSIDES
282Exanthema19148589CTD
283Eye InfectionOFFSIDES
284Fungus serology test positiveOFFSIDES
285GlaucomaOFFSIDES
286GranulocytosisOFFSIDES
287Grip strengthOFFSIDES
288Hemoglobinuria19148589CTD
289Hepatic InfarctionOFFSIDES
290Hepatitis BOFFSIDES
291HepatoblastomaOFFSIDES
292HepatosplenomegalyOFFSIDES
293Injection site maculeOFFSIDES
294Injection site pallorOFFSIDES
295Intraocular inflammationOFFSIDES
296Invasive Pulmonary Aspergillosis14661114CTD
297Kidney FailureOFFSIDES
298Large intestine anastomosisOFFSIDES
299Leukopenia neonatalOFFSIDES
300Lung consolidationOFFSIDES
301MalabsorptionOFFSIDES
302Mental status changesOFFSIDES
303Mycoses17015631CTD
304OsteopeniaOFFSIDES
305Pathogen resistanceOFFSIDES
306Plasminogen decreasedOFFSIDES
307Propofol Infusion SyndromeOFFSIDES
308PyelonephritisOFFSIDES
309Respiratory syncytial virus test positiveOFFSIDES
310Retrograde portal vein flowOFFSIDES
311Stenotrophomonas infectionOFFSIDES
312Urinary tract infection enterococcalOFFSIDES
313Ventricular Fibrillation19148589CTD
314Vitamin K DeficiencyOFFSIDES
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