MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

doxifluridine

(ZWAOHEXOSAUJHY-ZIYNGMLESA-N)

Structure

SMILES: C[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cc(F)c(=O)[nH]c1=O
Type(s): Investigational
Molecular Formula:: C9H11FN2O5
Molecular Weight:: 246.192
Log P:: -1.6852
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 3
TPSA:: 104.55
CAS Number(s):: 3094-09-5; 436349

Synonym(s)

doxifluridine

5'-DFUR

5'-deoxy-5'-fluorouridine

5'-deoxy-5-fluorouridine

5'-fluoro-5'-deoxyuridine

Furtulon

Ro 21-9738

doxyfluridine

External Link(s)

MeSH	C025034
PubChem Compound	18343
BindingDB	50132295
ChEBI	31521
CHEMBL	CHEMBL1130
DrugBank	DB12947
DrugCentral	958
KEGG	cpd:C12739 dr:D01309
Therapeutic Target Database	D03KXY
ZINC	1319177

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abscess		OFFSIDES
2	Angina Pectoris	2990750	CTD
3	Apathy		OFFSIDES
4	Ataxia	2941966	CTD
5	Bladder tamponade		OFFSIDES
6	Blood albumin decreased		OFFSIDES
7	Blood alkaline phosphatase increased		OFFSIDES
8	Blood creatinine decreased		OFFSIDES
9	Blood glucose decreased		OFFSIDES
10	Bone neoplasms	10791010 10969600	CTD
11	Brain Diseases	2941966 2996281	CTD
12	Breast cancer recurrent		OFFSIDES
13	Colonic Neoplasms	2942245 2990750	CTD
14	Colorectal Neoplasms	2996281	CTD
15	Completed Suicide		OFFSIDES
16	Confusion	2941966	CTD
17	Dental cleaning		OFFSIDES
18	Dental discomfort		OFFSIDES
19	Diarrhea	2942245	CTD OFFSIDES
20	Diplopia	2941966	CTD
21	Encephalitis		OFFSIDES
22	Endometrial Neoplasms	2942245	CTD
23	Failure of implant		OFFSIDES
24	Fistula discharge		OFFSIDES
25	Gait Disorders, Neurologic	15184640	CTD
26	Goiter		OFFSIDES
27	Hypersensitivity	2942245	CTD
28	Immunosuppression		OFFSIDES
29	Jaw lesion excision		OFFSIDES
30	Large intestine perforation		OFFSIDES
31	Leukopenia	2942245	CTD
32	Malignant neoplasm progression		OFFSIDES
33	Medical device removal		OFFSIDES
34	Monoparesis		OFFSIDES
35	Nausea	2942245	CTD
36	Neoplasm Metastasis	10969600	CTD
37	Neurotoxicity Syndromes	2942245 2990750	CTD
38	Oral Cavity Fistula		OFFSIDES
39	Osteolysis		OFFSIDES
40	Osteomyelitis		OFFSIDES
41	Periodontitis		OFFSIDES
42	Periostitis		OFFSIDES
43	Poor dental condition		OFFSIDES
44	Primary sequestrum		OFFSIDES
45	Pulmonary congestion		OFFSIDES
46	Purulent discharge		OFFSIDES
47	Rales		OFFSIDES
48	Rectal Neoplasms	2942245	CTD
49	Respiratory Failure		OFFSIDES
50	Secondary sequestrum		OFFSIDES
51	Stomach Neoplasms	2942245 15184640	CTD
52	Stridor		OFFSIDES
53	Sudden death		OFFSIDES
54	Thrombocytopenia	2942245	CTD
55	Tooth Extraction		OFFSIDES
56	Uterine Cancer		OFFSIDES
57	Vomiting	2942245	CTD

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