MetaADEDB 2.0 @ LMMD
chlordiazepoxide, clidinium drug combination
(DEFSGBLCSDNASK-UHFFFAOYSA-M)
Structure
SMILES
O=C(C(c1ccccc1)(c1ccccc1)O)OC1C[N+]2(C)CCC1CC2.CN=C1CN(O)C(=c2c(=N1)ccc(c2)Cl)c1ccccc1.[Br-]
Molecular Formula:
C38H40BrClN4O4
Molecular Weight:
732.106
Log P:
0.8900
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
2
TPSA:
94.72
CAS Number(s):
8015-20-1
Synonym(s)
1.
chlordiazepoxide, clidinium drug combination
2.
Librax
3.
Spasril
4.
chlordiazepoxide - clidinium
5.
chlordiazepoxide hydrochloride, clidinium bromide drug combination
6.
chlordiazepoxide hydrochloride-clidinium bromide combination
7.
chlordiazepoxide-clidinium combination
External Link(s)
MeSHC034153
PubChem Compound3080646
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Pharmaceutical product complaintFAERS: 6OFFSIDES
US FAERS
2HeadacheFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
3Medication ErrorFAERS: 3US FAERS
4NauseaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
5AstheniaFAERS: 2OFFSIDES
US FAERS
6ConstipationFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
7DizzinessFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
8FatigueFAERS: 2OFFSIDES
US FAERS
9MalaiseFAERS: 2US FAERS
10PalpitationsFAERS: 2US FAERS
11Pharyngolaryngeal PainFAERS: 2US FAERS
12VomitingFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
13Abdominal discomfortFAERS: 1OFFSIDES
US FAERS
14Accidental overdoseFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
15AdactylyFAERS: 1US FAERS
16Adverse eventFAERS: 1US FAERS
17AmnesiaFAERS: 1OFFSIDES
US FAERS
18Angina PectorisFAERS: 1US FAERS
19Chest PainFAERS: 1OFFSIDES
US FAERS
20Drug ineffectiveFAERS: 1US FAERS
21Electrocardiogram abnormalFAERS: 1US FAERS
22EpistaxisFAERS: 1US FAERS
23Expired product administeredFAERS: 1US FAERS
24Gastrointestinal PainFAERS: 1US FAERS
25HyperacusisFAERS: 1US FAERS
26HypersensitivityFAERS: 1US FAERS
27Joint injuryFAERS: 1US FAERS
28Ligament injuryFAERS: 1US FAERS
29NasopharyngitisFAERS: 1US FAERS
30NervousnessFAERS: 1US FAERS
31OverdoseFAERS: 1US FAERS
32Product formulation issueFAERS: 1US FAERS
33Product quality issueFAERS: 1US FAERS
34Product substitution issueFAERS: 1US FAERS
35SyndactylyFAERS: 1US FAERS
36Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
37TremorFAERS: 1US FAERS
38Urinary RetentionFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
39Abdominal PainOFFSIDES
40Abdominal rigidityOFFSIDES
41Abnormal visionOFFSIDES
42AbuseOFFSIDES
43AcanthomaOFFSIDES
44AcarodermatitisOFFSIDES
45Acid refluxOFFSIDES
46Activities of daily living impairedOFFSIDES
47Acute bronchitisOFFSIDES
48AdenocarcinomaOFFSIDES
49Adenomatous Polyposis ColiOFFSIDES
50AdenomaOFFSIDES
51Agonal rhythmOFFSIDES
52AgraphiaOFFSIDES
53Alcohol problemOFFSIDES
54AngioedemaOFFSIDES
55AnhedoniaOFFSIDES
56AnorexiaOFFSIDES
57AnxietyOFFSIDES
58AortitisOFFSIDES
59ApathyOFFSIDES
60ApneaOFFSIDES
61Application site excoriationOFFSIDES
62Application site pruritusOFFSIDES
63Application site swellingOFFSIDES
64ArthritisOFFSIDES
65ArthropathyOFFSIDES
66Aspiration PneumoniaOFFSIDES
67AsthmaOFFSIDES
68AtelectasisOFFSIDES
69Back disorderOFFSIDES
70Bile Duct StenosisOFFSIDES
71Biliary cirrhosisOFFSIDES
72Blood GlucoseOFFSIDES
73Blood alkaline phosphatase abnormalOFFSIDES
74Blood chloride decreasedOFFSIDES
75Blood cholesterolOFFSIDES
76Blood creatine phosphokinase MB increasedOFFSIDES
77Blood glucose decreasedOFFSIDES
78Blood iron increasedOFFSIDES
79Blood osmolarity decreasedOFFSIDES
80Blood pressure fluctuationOFFSIDES
81Blurred visionOFFSIDES
82Bone painOFFSIDES
83BradycardiaOFFSIDES
84Breast MicrocalcificationOFFSIDES
85BronchiectasisOFFSIDES
86BronchitisOFFSIDES
87BruxismOFFSIDES
88Bulbar palsyOFFSIDES
89Burning sensationOFFSIDES
90BursitisOFFSIDES
91Cardiac ablationOFFSIDES
92Carotid bruitOFFSIDES
93Cataract operationOFFSIDES
94CataractOFFSIDES
95Central nervous system lesionOFFSIDES
96Cervical laser therapyOFFSIDES
97Cervical myelopathyOFFSIDES
98Cholecystitis infectiveOFFSIDES
99ChondromalaciaOFFSIDES
100Chronic Obstructive Airway DiseaseOFFSIDES
101Chronic sinusitisOFFSIDES
102Chronic ulcerative colitisOFFSIDES
103Circumstance or information capable of leading to medication errorOFFSIDES
104CirrhosisOFFSIDES
105ColitisOFFSIDES
106Completed SuicideOFFSIDES
107Compression fractureOFFSIDES
108Congenital tricuspid valve incompetenceOFFSIDES
109Conjunctival depositOFFSIDES
110CyanosisOFFSIDES
111CystOFFSIDES
112DebridementOFFSIDES
113DemyelinationOFFSIDES
114Dental cariesOFFSIDES
115Dental discomfortOFFSIDES
116Denture wearerOFFSIDES
117Depressed Level of ConsciousnessOFFSIDES
118Depressed moodOFFSIDES
119Device breakageOFFSIDES
120DiarrheaOFFSIDES
121Disease recurrenceOFFSIDES
122DiverticulitisOFFSIDES
123DiverticulumOFFSIDES
124Drug administration errorOFFSIDES
125Drug level below therapeuticOFFSIDES
126Drug screen negativeOFFSIDES
127Drug toxicityOFFSIDES
128Drug withdrawal headacheOFFSIDES
129DysgeusiaOFFSIDES
130DyspepsiaOFFSIDES
131DysphoniaOFFSIDES
132DysuriaOFFSIDES
133Ear dischargeOFFSIDES
134Economic problemOFFSIDES
135Ejection Fraction DecreasedOFFSIDES
136Endometrial hypertrophyOFFSIDES
137EpicondylitisOFFSIDES
138ExcoriationOFFSIDES
139Eye InfectionOFFSIDES
140Eye painOFFSIDES
141Facial NeuralgiaOFFSIDES
142Fatty LiverOFFSIDES
143Fear of fallingOFFSIDES
144Febrile NeutropeniaOFFSIDES
145Feeling abnormalOFFSIDES
146FibromyalgiaOFFSIDES
147Flank PainOFFSIDES
148Flat affectOFFSIDES
149FlatulenceOFFSIDES
150FormicationOFFSIDES
151Fungal cystitisOFFSIDES
152Gastric BypassOFFSIDES
153GastroenteritisOFFSIDES
154Gastrointestinal perforationOFFSIDES
155Gastrointestinal stoma complicationOFFSIDES
156GranulomaOFFSIDES
157HamartomaOFFSIDES
158HemiparesisOFFSIDES
159HemiplegiaOFFSIDES
160Hepatitis B positiveOFFSIDES
161HiccoughOFFSIDES
162Hilar lymphadenopathyOFFSIDES
163HistoplasmosisOFFSIDES
164HydronephrosisOFFSIDES
165HypoxiaOFFSIDES
166Impaired gastric emptyingOFFSIDES
167Impaired work abilityOFFSIDES
168Implant site painOFFSIDES
169Incisional herniaOFFSIDES
170IncontinenceOFFSIDES
171InfectionOFFSIDES
172Injection site burningOFFSIDES
173Injection site erythemaOFFSIDES
174Injection site inflammationOFFSIDES
175Injection site phlebitisOFFSIDES
176Injection site stingingOFFSIDES
177Injection site warmthOFFSIDES
178Intermittent ClaudicationOFFSIDES
179Intervertebral Disc DegenerationOFFSIDES
180Intervertebral disc disorderOFFSIDES
181Intestinal ObstructionOFFSIDES
182Intracranial HypotensionOFFSIDES
183IritisOFFSIDES
184Irritable Bowel Syndrome9063050CTD
185LaryngospasmCanada Vigilance: 1Canada Vigilance
186Leukopenia neonatalOFFSIDES
187Limb injuryOFFSIDES
188Lung InjuryOFFSIDES
189MastectomyOFFSIDES
190Mastication disorderOFFSIDES
191Mechanical ventilationOFFSIDES
192Medical device complicationOFFSIDES
193Mental status changesOFFSIDES
194Mixed liver injuryOFFSIDES
195Multiple MyelomaOFFSIDES
196Multiple SclerosisOFFSIDES
197Multiple allergiesOFFSIDES
198Multiple drug overdoseOFFSIDES
199Nail pickingOFFSIDES
200Nervous tensionOFFSIDES
201NeuralgiaOFFSIDES
202NocturiaOFFSIDES
203Nodule on extremityOFFSIDES
204Open woundOFFSIDES
205Optic AtrophyOFFSIDES
206Optic Disc EdemaOFFSIDES
207Optic NeuritisOFFSIDES
208Osteitis DeformansOFFSIDES
209OsteolysisOFFSIDES
210OsteomyelitisOFFSIDES
211OsteopeniaOFFSIDES
212OsteoporosisOFFSIDES
213PainOFFSIDES
214Pancreatic Duct StenosisOFFSIDES
215Pelvic InfectionOFFSIDES
216Pelvic abscessOFFSIDES
217Pelvic discomfortOFFSIDES
218Pericardial effusionOFFSIDES
219PeriodontitisOFFSIDES
220PeritonitisOFFSIDES
221PhlebitisOFFSIDES
222PlasmacytomaOFFSIDES
223PleurisyOFFSIDES
224PolyuriaOFFSIDES
225Post lumbar puncture syndromeOFFSIDES
226Posterior CapsulotomyOFFSIDES
227Posterior capsule opacificationOFFSIDES
228PouchitisOFFSIDES
229Productive CoughOFFSIDES
230Prostatic ObstructionOFFSIDES
231PsoriasisOFFSIDES
232Pulmonary HypertensionOFFSIDES
233PyuriaOFFSIDES
234RalesOFFSIDES
235Rash erythematousCanada Vigilance: 1Canada Vigilance
236Rectal polypOFFSIDES
237Renal Artery StenosisOFFSIDES
238Respiratory FailureOFFSIDES
239Sick Sinus SyndromeOFFSIDES
240SinusitisOFFSIDES
241SomnolenceCanada Vigilance: 1Canada Vigilance
242Sphincter of Oddi DysfunctionOFFSIDES
243Spinal column stenosisOFFSIDES
244Spinal fusion surgeryOFFSIDES
245SpondylitisOFFSIDES
246SpondylolisthesisOFFSIDES
247Sputum culture positiveOFFSIDES
248Staphylococcal Scalded Skin SyndromeOFFSIDES
249Stem cell transplantOFFSIDES
250Stent occlusionOFFSIDES
251StressOFFSIDES
252Subcutaneous EmphysemaOFFSIDES
253Subcutaneous noduleOFFSIDES
254Substance Withdrawal Syndrome9063050CTD
255Supraventricular tachycardiaOFFSIDES
256SynovitisOFFSIDES
257TenosynovitisOFFSIDES
258TinnitusOFFSIDES
259Tooth ExtractionOFFSIDES
260Tooth LossOFFSIDES
261UlcerOFFSIDES
262Umbilical herniaOFFSIDES
263UrticariaCanada Vigilance: 5Canada Vigilance
264Uterine RuptureOFFSIDES
265VIIth nerve paralysisOFFSIDES
266Vaginal lesionOFFSIDES
267Vaginal mycosisOFFSIDES
268VertebroplastyOFFSIDES
269Viral rhinitisOFFSIDES
270Viral upper respiratory tract infectionOFFSIDES
271Visual disturbanceOFFSIDES
272Vocal Cord ParalysisOFFSIDES
273Vulvovaginal discomfortOFFSIDES
274Weight GainOFFSIDES
275Withdrawal of life supportOFFSIDES
276Wound InfectionOFFSIDES
277effusionOFFSIDES
278jaundiceCanada Vigilance: 1Canada Vigilance
279muscle injuryOFFSIDES
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