MetaADEDB 2.0 @ LMMD
Cisapride
(DCSUBABJRXZOMT-UHFFFAOYSA-N)
Structure
SMILES
COC1CN(CCCOc2ccc(cc2)F)CCC1NC(=O)c1cc(Cl)c(cc1OC)N
Molecular Formula:
C23H29ClFN3O4
Molecular Weight:
465.945
Log P:
4.2681
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
2
TPSA:
86.05
CAS Number(s):
81098-60-4; 104860-73-3
Synonym(s)
1.
Cisapride
2.
Propulsid
3.
R-51619
4.
R 51619
5.
R51619
External Link(s)
MeSHD020117
PubChem Compound2769
BindingDB50005836
ChEBI95129
CHEMBLCHEMBL1729
DrugCentral660
IUPHAR/BPS Guide to PHARMACOLOGY240
KEGGcpd:C06910
dr:D00274
Therapeutic Target DatabaseD0N1BQ
D0BD8D
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Ventricular FibrillationFAERS: 64
Canada Vigilance: 2		11419817
15640612		CTD
OFFSIDES
Canada Vigilance
US FAERS
2PalpitationsFAERS: 47
Canada Vigilance: 2		Canada Vigilance
US FAERS
3DisabilityFAERS: 31US FAERS
4Drug ineffectiveFAERS: 19
Canada Vigilance: 2		Canada Vigilance
US FAERS
5NauseaFAERS: 15US FAERS
6VomitingFAERS: 15
Canada Vigilance: 2		Canada Vigilance
US FAERS
7Impaired gastric emptyingFAERS: 14OFFSIDES
US FAERS
8Chest PainFAERS: 10
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
9PneumoniaFAERS: 10US FAERS
10AnxietyFAERS: 8
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
11PainFAERS: 810604046CTD
OFFSIDES
US FAERS
12SyncopeFAERS: 812075394
17070606		CTD
US FAERS
13AnorexiaFAERS: 7US FAERS
14ConstipationFAERS: 7
Canada Vigilance: 1		9669632
11578711		CTD
Canada Vigilance
US FAERS
15Myocardial InfarctionFAERS: 7
Canada Vigilance: 2		Canada Vigilance
US FAERS
16TachycardiaFAERS: 77886817
16040888		CTD
US FAERS
17Abdominal PainFAERS: 6
Canada Vigilance: 2		9669632CTD
OFFSIDES
Canada Vigilance
US FAERS
18Drug dose omissionFAERS: 6US FAERS
19CachexiaFAERS: 5US FAERS
20Cardiac ArrestFAERS: 5
Canada Vigilance: 4		Canada Vigilance
US FAERS
21Cerebrovascular accidentFAERS: 5
Canada Vigilance: 2		Canada Vigilance
US FAERS
22PallorFAERS: 5OFFSIDES
US FAERS
23Completed SuicideFAERS: 4OFFSIDES
US FAERS
24CyanosisFAERS: 4US FAERS
25DehydrationFAERS: 4OFFSIDES
US FAERS
26Gastrointestinal obstructionFAERS: 4OFFSIDES
US FAERS
27Intestinal ObstructionFAERS: 4US FAERS
28Malignant neoplasm progressionFAERS: 4OFFSIDES
US FAERS
29Product availability issueFAERS: 4US FAERS
30Septic ShockFAERS: 4US FAERS
31Transaminases increasedFAERS: 4US FAERS
32Urinary tract infectionFAERS: 4US FAERS
33Acquired pyloric stenosisFAERS: 3OFFSIDES
US FAERS
34Chest discomfortFAERS: 3US FAERS
35Coronary Artery DiseaseFAERS: 3US FAERS
36DizzinessFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
37FatigueFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
38Feeling abnormalFAERS: 3US FAERS
39HypoxiaFAERS: 3US FAERS
40InfectionFAERS: 3OFFSIDES
US FAERS
41MalaiseFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
42Pancreatic carcinomaFAERS: 3US FAERS
43Post procedural complicationFAERS: 3OFFSIDES
US FAERS
44Respiratory FailureFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
45SuperinfectionFAERS: 3US FAERS
46Supraventricular tachycardiaFAERS: 3OFFSIDES
US FAERS
47Unevaluable eventFAERS: 3US FAERS
48UrticariaFAERS: 3US FAERS
49AcidosisFAERS: 2US FAERS
50Adverse eventFAERS: 2US FAERS
51Angina PectorisFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
52Atrial thrombosisFAERS: 2US FAERS
53BradycardiaFAERS: 28636830
14730156
22744888		CTD
US FAERS
54BronchitisFAERS: 2OFFSIDES
US FAERS
55Cardiac DeathFAERS: 2OFFSIDES
US FAERS
56Central line infectionFAERS: 2OFFSIDES
US FAERS
57ChokingFAERS: 2US FAERS
58Colonic Pseudo-ObstructionFAERS: 2OFFSIDES
US FAERS
59DuodenitisFAERS: 2US FAERS
60Eosinophil percentage increasedFAERS: 2US FAERS
61Foaming at mouthFAERS: 2US FAERS
62Gastric outlet obstructionFAERS: 2OFFSIDES
US FAERS
63General physical health deteriorationFAERS: 2OFFSIDES
US FAERS
64HepatitisFAERS: 2US FAERS
65HyperventilationFAERS: 2US FAERS
66Infection in an immunocompromised hostFAERS: 2US FAERS
67Intestinal hypomotilityFAERS: 2OFFSIDES
US FAERS
68IntussusceptionFAERS: 2US FAERS
69Lymphocyte percentage increasedFAERS: 2US FAERS
70Muscle hypertrophyFAERS: 2US FAERS
71Neutrophil percentage decreasedFAERS: 2US FAERS
72PCO2 decreasedFAERS: 2US FAERS
73PeritonitisFAERS: 2OFFSIDES
US FAERS
74Postoperative infectionFAERS: 2US FAERS
75SepsisFAERS: 2US FAERS
76Sinus TachycardiaFAERS: 2US FAERS
77Sinus bradycardiaFAERS: 2OFFSIDES
US FAERS
78StressFAERS: 2US FAERS
79Sudden deathFAERS: 2OFFSIDES
US FAERS
80Ventricular hypertrophyFAERS: 2US FAERS
81AlopeciaFAERS: 1US FAERS
82AmnesiaFAERS: 1US FAERS
83AmyloidosisFAERS: 1US FAERS
84Anal sphincter atonyFAERS: 1US FAERS
85ArteriosclerosisFAERS: 1US FAERS
86AstheniaFAERS: 1US FAERS
87Atrial FibrillationFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
88Benign bone neoplasmFAERS: 1US FAERS
89Blood glucose fluctuationFAERS: 1OFFSIDES
US FAERS
90BronchopneumoniaFAERS: 1OFFSIDES
US FAERS
91BronchopneumopathyFAERS: 1OFFSIDES
US FAERS
92Bronchopulmonary DysplasiaFAERS: 1OFFSIDES
US FAERS
93CholelithiasisFAERS: 1US FAERS
94Chronic respiratory failureFAERS: 1US FAERS
95Cold sweatFAERS: 1US FAERS
96CryingFAERS: 1US FAERS
97Diabetes MellitusFAERS: 1US FAERS
98Disease ProgressionFAERS: 1US FAERS
99Drug exposure before pregnancyFAERS: 1US FAERS
100Drug prescribing errorFAERS: 1US FAERS
101DyspepsiaFAERS: 110604046
17070606		CTD
US FAERS
102Echocardiogram abnormalFAERS: 1US FAERS
103Electrolyte imbalanceFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
104EmbolismFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
105EnuresisFAERS: 1US FAERS
106Expired product administeredFAERS: 1US FAERS
107FormicationFAERS: 1US FAERS
108FractureFAERS: 1US FAERS
109Gastric StenosisFAERS: 1US FAERS
110Gastric ulcerFAERS: 1US FAERS
111Gastroenteritis sapovirusFAERS: 1US FAERS
112Gastrointestinal motility disorderFAERS: 1US FAERS
113Gastrointestinal stoma complicationFAERS: 1US FAERS
114HerniaFAERS: 1US FAERS
115IncontinenceFAERS: 1OFFSIDES
US FAERS
116Incorrect dose administeredFAERS: 1US FAERS
117Incorrect product formulation administeredFAERS: 1US FAERS
118InfarctionFAERS: 1US FAERS
119InfluenzaFAERS: 1US FAERS
120Irritable Bowel SyndromeFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
121Laboratory test interferenceFAERS: 1US FAERS
122Markedly reduced dietary intakeFAERS: 1OFFSIDES
US FAERS
123MenorrhagiaFAERS: 1US FAERS
124Mental impairmentFAERS: 1US FAERS
125Metabolic acidosisFAERS: 1US FAERS
126MetastasisFAERS: 1US FAERS
127Muscle FatigueFAERS: 1US FAERS
128Muscle tightnessFAERS: 1US FAERS
129Muscular DystrophyFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
130Neonatal disorderFAERS: 1US FAERS
131NervousnessFAERS: 1US FAERS
132Neurogenic BowelFAERS: 1US FAERS
133ObstructionFAERS: 1US FAERS
134OsteoporosisFAERS: 1US FAERS
135OverweightFAERS: 1US FAERS
136PO2 increasedFAERS: 1US FAERS
137Pancreatic NeoplasmFAERS: 1US FAERS
138Parkinsonian rest tremorFAERS: 1US FAERS
139Platelet count abnormalFAERS: 1US FAERS
140PolymyalgiaFAERS: 1US FAERS
141PolymyositisFAERS: 1US FAERS
142Product label confusionFAERS: 1US FAERS
143Pulmonary EmbolismFAERS: 1US FAERS
144QRS axis abnormalFAERS: 1US FAERS
145Rectal ProlapseFAERS: 1US FAERS
146RegurgitationFAERS: 1US FAERS
147Respiratory arrestFAERS: 1US FAERS
148Respiratory distressFAERS: 1US FAERS
149Respiratory tract infection viralFAERS: 1US FAERS
150ScreamingFAERS: 1OFFSIDES
US FAERS
151ShockFAERS: 1US FAERS
152Sinus ArrhythmiaFAERS: 1US FAERS
153Small intestine carcinoma recurrentFAERS: 1US FAERS
154Small intestine carcinomaFAERS: 1US FAERS
155SpondylolisthesisFAERS: 1US FAERS
156Sudden infant death syndromeFAERS: 1OFFSIDES
US FAERS
157Suicide attemptFAERS: 1US FAERS
158SwellingFAERS: 1US FAERS
159ThrombosisFAERS: 1US FAERS
160Tumour haemorrhageFAERS: 1US FAERS
161Ventricular arrhythmiaFAERS: 1US FAERS
162Viral upper respiratory tract infectionFAERS: 1US FAERS
163Wound InfectionFAERS: 1US FAERS
164Wrong technique in product usage processFAERS: 1US FAERS
165nervous system disorderFAERS: 1US FAERS
166Abdominal discomfortOFFSIDES
167Acid refluxOFFSIDES
168ActinomycosisOFFSIDES
169Activities of daily living impairedOFFSIDES
170Acute glomerulonephritisOFFSIDES
171Acute sinusitisOFFSIDES
172AdenitisOFFSIDES
173AdenoidectomyOFFSIDES
174AdenomaOFFSIDES
175Adrenal Gland Diseases12519861CTD
176Adrenal cystOFFSIDES
177Agitation postoperativeOFFSIDES
178AlveolitisOFFSIDES
179AlveoloplastyOFFSIDES
180AneurysmOFFSIDES
181AnhedoniaOFFSIDES
182AnhidrosisOFFSIDES
183Anoxic EncephalopathyOFFSIDES
184Aortic valve calcificationOFFSIDES
185Aortic valve sclerosisOFFSIDES
186AphoniaOFFSIDES
187ApneaOFFSIDES
188Arterial insufficiencyOFFSIDES
189ArthritisOFFSIDES
190Aspiration PneumoniaOFFSIDES
191AsterixisOFFSIDES
192AtelectasisOFFSIDES
193Atrial tachycardiaOFFSIDES
194Atrioventricular BlockCanada Vigilance: 112595600CTD
Canada Vigilance
195Autonomic neuropathyOFFSIDES
196Back PainCanada Vigilance: 1Canada Vigilance
197Bacteria tissue specimen identifiedOFFSIDES
198Bacterial test positiveOFFSIDES
199Biliary dilatationOFFSIDES
200BlepharoptosisOFFSIDES
201Blood iron decreasedOFFSIDES
202Blood magnesium decreasedOFFSIDES
203Blood magnesium increasedOFFSIDES
204Blood potassium decreasedOFFSIDES
205Bone density decreasedOFFSIDES
206Bone erosionOFFSIDES
207Bone fragmentationOFFSIDES
208Bone lesionOFFSIDES
209Bone swellingOFFSIDES
210Bone trimmingOFFSIDES
211Borderline Personality DisorderOFFSIDES
212BruxismOFFSIDES
213Cardiac FlutterOFFSIDES
214Cardiac stress test abnormalOFFSIDES
215Cardioactive drug level increasedOFFSIDES
216Cardiomegaly16040888CTD
217Cardiomyopathy, Dilated16040888CTD
218Carotid artery aneurysmOFFSIDES
219Carotid artery occlusionOFFSIDES
220Carotid intima-media thickness increasedOFFSIDES
221CataractOFFSIDES
222Catheter related complicationOFFSIDES
223Catheter site infectionOFFSIDES
224CellulitisOFFSIDES
225Cerebral artery occlusionOFFSIDES
226Cerebral atrophyOFFSIDES
227Cervicobrachial syndromeOFFSIDES
228Chemical and Drug Induced Liver Injury1397860
22166485		CTD
229Choking sensationOFFSIDES
230Cholecystitis infectiveOFFSIDES
231CholecystitisOFFSIDES
232Cholelithiasis obstructiveOFFSIDES
233Chronic Obstructive Airway DiseaseOFFSIDES
234Circumstance or information capable of leading to medication errorOFFSIDES
235CirrhosisOFFSIDES
236Congenital hypertrichosisOFFSIDES
237Congenital tricuspid valve incompetenceOFFSIDES
238Coronary angioplastyOFFSIDES
239Cushing Syndrome12519861CTD
240CystOFFSIDES
241Deglutition Disorders7723193CTD
242Delusional disorder, unspecified typeOFFSIDES
243DemyelinationOFFSIDES
244Dental FistulaOFFSIDES
245Dental PlaqueOFFSIDES
246Dental cariesOFFSIDES
247Dental discomfortOFFSIDES
248Dental examinationOFFSIDES
249Denture wearerOFFSIDES
250DependenceOFFSIDES
251Depressed moodOFFSIDES
252Diabetes InsipidusOFFSIDES
253Diabetic FootOFFSIDES
254Diabetic RetinopathyOFFSIDES
255Diverticular perforationOFFSIDES
256DiverticulosisOFFSIDES
257DiverticulumOFFSIDES
258Dolichocolon acquiredOFFSIDES
259Drug ToleranceOFFSIDES
260Drug abuserOFFSIDES
261Drug addictOFFSIDES
262Drug toxicityOFFSIDES
263Duodenal Ulcer11578711CTD
264DysphasiaOFFSIDES
265DysphoniaOFFSIDES
266Dyspnea7723193CTD
267Dystonia15506326CTD
268Ear congestionOFFSIDES
269Ear discomfortOFFSIDES
270Economic problemOFFSIDES
271EczemaOFFSIDES
272Electrocardiogram ST segment abnormalOFFSIDES
273Electrocardiogram ST-T segment abnormalOFFSIDES
274Electrocardiogram poor R-wave progressionOFFSIDES
275Emotional distressOFFSIDES
276Empty Sella SyndromeOFFSIDES
277EndarterectomyOFFSIDES
278Endodontic procedureOFFSIDES
279Endometrial HyperplasiaOFFSIDES
280Eosinophilic myocarditisOFFSIDES
281EpistaxisOFFSIDES
282Erythema InfectiosumOFFSIDES
283Escherichia infectionOFFSIDES
284Escherichia sepsisOFFSIDES
285Escherichia urinary tract infectionOFFSIDES
286Esophageal StenosisOFFSIDES
287Ethmoid sinus surgeryOFFSIDES
288ExcoriationOFFSIDES
289External ear painOFFSIDES
290Failure to ThriveOFFSIDES
291Fatty LiverOFFSIDES
292Feeding disorder neonatalOFFSIDES
293Feeding problem in childOFFSIDES
294Feeding tube complicationOFFSIDES
295Feeling ColdCanada Vigilance: 1Canada Vigilance
296Fluid overloadOFFSIDES
297Gait Disorders, Neurologic7723193CTD
298Gastric DilatationOFFSIDES
299Gastrointestinal hypomotilityOFFSIDES
300Gastroparesis11578711
15961989		CTD
301GastrostomyOFFSIDES
302Gaze palsyOFFSIDES
303Gingival graftOFFSIDES
304GlobulinuriaOFFSIDES
305GoiterOFFSIDES
306GoutOFFSIDES
307Graft infectionOFFSIDES
308Heart Diseases22166485CTD
309Hepatitis AOFFSIDES
310HepatosplenomegalyOFFSIDES
311HyperkeratosisOFFSIDES
312HyperkinesiaCanada Vigilance: 2Canada Vigilance
313Hyperplasia12519861CTD
314Hypertrophic CardiomyopathyOFFSIDES
315HypokinesiaOFFSIDES
316HypophagiaOFFSIDES
317HypotensionCanada Vigilance: 115115163CTD
Canada Vigilance
318Immunosuppressant drug levelOFFSIDES
319Increased bronchial secretionOFFSIDES
320Infantile vomitingCanada Vigilance: 1Canada Vigilance
321InfertilityOFFSIDES
322Injury asphyxiationOFFSIDES
323Intervertebral Disc DegenerationOFFSIDES
324Intervertebral disc disorderOFFSIDES
325Intestinal resectionOFFSIDES
326IntubationOFFSIDES
327Joint Range of Motion DecreasedOFFSIDES
328Joint injuryOFFSIDES
329Kidney FailureOFFSIDES
330Labile hypertensionOFFSIDES
331LeukocytosisCanada Vigilance: 1Canada Vigilance
332LeukoplakiaOFFSIDES
333Life expectancy shortenedOFFSIDES
334Ligament injuryOFFSIDES
335Limb injuryOFFSIDES
336Lip swellingCanada Vigilance: 1Canada Vigilance
337Long QT Syndrome

View details

8636830
9545159
10206861
10355701
10560562
10943965
11001179
11099628
11389249
11419817
11479406
11578711
12075394
12208804
12239699
12595600
12682804
12912819
15717139
16040888
16278312
16290300
16301357
18472280
20636881
24052561
 		CTD
338Loose toothOFFSIDES
339Lumbar radiculopathyOFFSIDES
340Lung consolidationOFFSIDES
341Lymphocyte count decreasedOFFSIDES
342Macular reflex abnormalOFFSIDES
343MeningiomaOFFSIDES
344Mental status changesOFFSIDES
345MetamorphopsiaOFFSIDES
346Multiple MyelomaOFFSIDES
347Muscle Rigidity7723193CTD
348Muscle WeaknessOFFSIDES
349Musculoskeletal discomfortOFFSIDES
350Nail InfectionOFFSIDES
351NasopharyngitisOFFSIDES
352Nephrogenic Fibrosing DermopathyOFFSIDES
353Nicotine DependenceOFFSIDES
354NocturiaOFFSIDES
355Nodule on extremityOFFSIDES
356NystagmusOFFSIDES
357Optic AtrophyOFFSIDES
358Oral Cavity FistulaOFFSIDES
359Oral mucosa atrophyOFFSIDES
360Oropharyngeal discomfortOFFSIDES
361Oropharyngeal painOFFSIDES
362OsteolysisOFFSIDES
363OsteomyelitisOFFSIDES
364OsteoradionecrosisOFFSIDES
365OsteosclerosisOFFSIDES
366OverdoseOFFSIDES
367Pain of skinOFFSIDES
368PancreatitisCanada Vigilance: 1Canada Vigilance
OFFSIDES
369Panic DisorderOFFSIDES
370ParacentesisOFFSIDES
371ParanoiaOFFSIDES
372Pericardial effusion22744888CTD
OFFSIDES
373Pharyngeal lesionOFFSIDES
374Pharyngolaryngeal PainOFFSIDES
375PhonophobiaOFFSIDES
376PlasmacytosisOFFSIDES
377PolyneuropathyOFFSIDES
378Polysubstance abuseOFFSIDES
379PolyuriaCanada Vigilance: 1Canada Vigilance
OFFSIDES
380Poor dental conditionOFFSIDES
381Postmenopausal bleedingOFFSIDES
382Pressure of speechOFFSIDES
383Prinzmetal's variant angina9740492CTD
384Propofol Infusion SyndromeOFFSIDES
385PruritusCanada Vigilance: 1Canada Vigilance
386Psychoses, Substance-Induced9075269CTD
387Pulmonary HypertensionOFFSIDES
388Purulent dischargeOFFSIDES
389Pyloric StenosisOFFSIDES
390Pyogenic granulomaOFFSIDES
391Rectal polypOFFSIDES
392Renal Insufficiency22166485CTD
393Retinal vascular occlusionOFFSIDES
394RhinalgiaOFFSIDES
395RhinitisOFFSIDES
396Rift Valley FeverOFFSIDES
397Ruptured cerebral aneurysmOFFSIDES
398ScotomaOFFSIDES
399Sinus antrostomyOFFSIDES
400Sinus operationOFFSIDES
401Skin IndurationOFFSIDES
402Skin hypertrophyOFFSIDES
403Skin neoplasm excisionOFFSIDES
404Skin tightnessOFFSIDES
405SomnolenceCanada Vigilance: 1Canada Vigilance
406Spinal column stenosisOFFSIDES
407Spinal fusion surgeryOFFSIDES
408SpondylosisOFFSIDES
409Stem cell transplantOFFSIDES
410Subcutaneous EmphysemaOFFSIDES
411Tachycardia, Ventricular11419817
12595600
17070606		CTD
412Tardive DyskinesiaOFFSIDES
413Temporal ArteritisOFFSIDES
414Therapeutic response unexpectedCanada Vigilance: 1Canada Vigilance
415ThrombocytopeniaCanada Vigilance: 1Canada Vigilance
416TinnitusOFFSIDES
417Tooth ExtractionOFFSIDES
418Tooth InfectionOFFSIDES
419Tooth LossOFFSIDES
420Tooth repairOFFSIDES
421Torsades de Pointes

View details

9292575
9545159
9817562
9972380
10355701
11419817
11569530
11858397
12208804
12239699
12595600
12912819
15640612
15869686
16301357
17070606
20064605
 		CTD
422Tricuspid valve sclerosisOFFSIDES
423UlcerOFFSIDES
424Uterine CancerOFFSIDES
425Uterine PolypOFFSIDES
426VIIth nerve paralysisOFFSIDES
427Vagus Nerve DisorderOFFSIDES
428Ventricular Dysfunction, Left16040888CTD
429VertigoCanada Vigilance: 1Canada Vigilance
430Weight decreasedCanada Vigilance: 1Canada Vigilance
431Wheelchair userOFFSIDES
432Wound dehiscenceOFFSIDES
433fibromaOFFSIDES
434prostatitisOFFSIDES
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