Sildenafil Citrate
(DEIYFTQMQPDXOT-UHFFFAOYSA-N)
Structure
- SMILES
- OC(=O)C(CC(=O)O)(CC(=O)O)O.CCCc1nn(c2c1nc([nH]c2=O)c1cc(ccc1OCC)S(=O)(=O)N1CCN(CC1)C)C
- Molecular Formula:
- C28H38N6O11S
- Molecular Weight:
- 666.700
- Log P:
- 1.3190
- Hydrogen Bond Acceptor:
- 16
- Hydrogen Bond Donor:
- 5
- TPSA:
- 253.93
- CAS Number(s):
- 171599-83-0
Synonym(s)
1.
Sildenafil Citrate
2.
1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
3.
Acetildenafil
4.
Desmethyl Sildenafil
5.
Desmethylsildenafil
6.
Homosildenafil
7.
Hydroxyhomosildenafil
8.
NCX-911
9.
Revatio
10.
Sildenafil
11.
Sildenafil Lactate
12.
Sildenafil Nitrate
13.
UK 92480-10
14.
UK-92,480-10
15.
Viagra
16.
Citrate, Sildenafil
17.
Lactate, Sildenafil
18.
NCX 911
19.
NCX911
20.
Nitrate, Sildenafil
21.
Sildenafil, Desmethyl
22.
UK 92,480 10
23.
UK 92480 10
24.
UK 9248010
External Link(s)
| MeSH | D000068677 |
| PubChem Compound | 135413523 |
| BindingDB | 50359766 |
| ChEBI | 58987 |
| CHEMBL | CHEMBL1737 |
| KEGG | dr:D02229 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Product use issue | FAERS: 290 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 2 | Drug ineffective | FAERS: 276 Canada Vigilance: 146 | Canada Vigilance US FAERS | |
| 3 | Malaise | FAERS: 261 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 4 | Pulmonary Hypertension | FAERS: 225 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Pneumonia | FAERS: 137 | 21414392 | CTD US FAERS |
| 6 | Hypotension | FAERS: 97 Canada Vigilance: 11 | CTD Canada Vigilance US FAERS | |
| 7 | Headache | FAERS: 96 Canada Vigilance: 9 | 16940217 18537952 18936500 | CTD Canada Vigilance US FAERS |
| 8 | Product use in unapproved indication | FAERS: 71 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 9 | Intentional product misuse | FAERS: 57 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 10 | Dizziness | FAERS: 56 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 11 | Myocardial Infarction | FAERS: 54 Canada Vigilance: 2 | CTD Canada Vigilance US FAERS | |
| 12 | Respiratory Failure | FAERS: 50 | US FAERS | |
| 13 | Visual Impairment | FAERS: 48 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 14 | Asthenia | FAERS: 46 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 15 | Drug ineffective for unapproved indication | FAERS: 46 | US FAERS | |
| 16 | Cerebrovascular accident | FAERS: 45 | US FAERS | |
| 17 | Influenza | FAERS: 45 | US FAERS | |
| 18 | Pain | FAERS: 44 | 16305795 18936500 | CTD US FAERS |
| 19 | Nasopharyngitis | FAERS: 39 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 20 | Disease Progression | FAERS: 38 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 21 | Fatigue | FAERS: 38 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 22 | Chest Pain | FAERS: 36 Canada Vigilance: 1 | 10475830 | CTD Canada Vigilance US FAERS |
| 23 | Feeling abnormal | FAERS: 36 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 24 | Weight decreased | FAERS: 36 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 25 | Prescribed overdose | FAERS: 35 | US FAERS | |
| 26 | Cardiac Arrest | FAERS: 33 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 27 | Atrial Fibrillation | FAERS: 32 | 10737566 10910376 | CTD US FAERS |
| 28 | Intentional product use issue | FAERS: 32 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 29 | Drug effect incomplete | FAERS: 30 | US FAERS | |
| 30 | Memory impairment | FAERS: 30 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 31 | Pulmonary Fibrosis | FAERS: 29 | US FAERS | |
| 32 | Sepsis | FAERS: 29 | US FAERS | |
| 33 | Drug dose omission | FAERS: 28 | US FAERS | |
| 34 | Epistaxis | FAERS: 26 | US FAERS | |
| 35 | Diabetes Mellitus | FAERS: 25 | US FAERS | |
| 36 | Flushing | FAERS: 24 Canada Vigilance: 5 | 18537952 | CTD Canada Vigilance US FAERS |
| 37 | Nausea | FAERS: 23 Canada Vigilance: 4 | 18936500 | CTD Canada Vigilance US FAERS |
| 38 | Arthropathy | FAERS: 22 | US FAERS | |
| 39 | Infection | FAERS: 22 | US FAERS | |
| 40 | Overdose | FAERS: 22 | US FAERS | |
| 41 | Therapeutic response unexpected | FAERS: 22 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 42 | Vomiting | FAERS: 22 | US FAERS | |
| 43 | Dyspepsia | FAERS: 21 Canada Vigilance: 1 | 16940217 18936500 | CTD Canada Vigilance US FAERS |
| 44 | Right ventricular failure | FAERS: 21 | US FAERS | |
| 45 | Bronchitis | FAERS: 20 | US FAERS | |
| 46 | Cataract | FAERS: 20 | US FAERS | |
| 47 | Thrombosis | FAERS: 20 | US FAERS | |
| 48 | Blindness | FAERS: 19 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 49 | Pre-existing condition improved | FAERS: 19 | US FAERS | |
| 50 | Scleroderma | FAERS: 18 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 51 | Suspected counterfeit product | FAERS: 18 Canada Vigilance: 15 | Canada Vigilance US FAERS | |
| 52 | Terminal state | FAERS: 18 | US FAERS | |
| 53 | Abdominal discomfort | FAERS: 17 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 54 | Deafness | FAERS: 17 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 55 | Expired product administered | FAERS: 17 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 56 | Palpitations | FAERS: 17 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 57 | Peripheral swelling | FAERS: 17 | US FAERS | |
| 58 | Stress | FAERS: 17 | US FAERS | |
| 59 | Dehydration | FAERS: 15 | US FAERS | |
| 60 | Dysphonia | FAERS: 14 | US FAERS | |
| 61 | General physical health deterioration | FAERS: 14 | US FAERS | |
| 62 | Hypoxia | FAERS: 14 | US FAERS | |
| 63 | Incorrect dose administered | FAERS: 14 | US FAERS | |
| 64 | Tremor | FAERS: 14 | US FAERS | |
| 65 | Back Pain | FAERS: 13 | US FAERS | |
| 66 | Erythema | FAERS: 13 | US FAERS | |
| 67 | Keratitis | FAERS: 13 | US FAERS | |
| 68 | Pulmonary arterial hypertension | FAERS: 13 | US FAERS | |
| 69 | Acute myocardial infarction | FAERS: 12 | US FAERS | |
| 70 | Arthralgia | FAERS: 12 | US FAERS | |
| 71 | Arthritis | FAERS: 12 | US FAERS | |
| 72 | Cellulitis | FAERS: 12 | US FAERS | |
| 73 | Low Cardiac Output Syndrome | FAERS: 12 | US FAERS | |
| 74 | Sinusitis | FAERS: 12 | US FAERS | |
| 75 | Amnesia | FAERS: 11 | US FAERS | |
| 76 | Cerebral Infarction | FAERS: 11 | US FAERS | |
| 77 | Myalgia | FAERS: 11 | US FAERS | |
| 78 | No adverse event | FAERS: 11 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 79 | Priapism | FAERS: 11 | 17952749 | CTD US FAERS |
| 80 | Product substitution issue | FAERS: 11 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 81 | Skin Ulcer | FAERS: 11 | US FAERS | |
| 82 | Syncope | FAERS: 11 | US FAERS | |
| 83 | Urinary tract infection | FAERS: 11 | US FAERS | |
| 84 | Acute kidney injury | FAERS: 10 | US FAERS | |
| 85 | Chest discomfort | FAERS: 10 | US FAERS | |
| 86 | Nervousness | FAERS: 10 | US FAERS | |
| 87 | Oropharyngeal pain | FAERS: 10 | US FAERS | |
| 88 | Swelling | FAERS: 10 | US FAERS | |
| 89 | Thrombocytopenia | FAERS: 10 | US FAERS | |
| 90 | Tinnitus | FAERS: 10 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 91 | Acute respiratory failure | FAERS: 9 | US FAERS | |
| 92 | Drug administered to patient of inappropriate age | FAERS: 9 | US FAERS | |
| 93 | Drug dispensing error | FAERS: 9 | US FAERS | |
| 94 | Lethargy | FAERS: 9 | US FAERS | |
| 95 | Pulmonary hypertensive crisis | FAERS: 9 | US FAERS | |
| 96 | Retinal toxicity | FAERS: 9 | US FAERS | |
| 97 | Septic Shock | FAERS: 9 | US FAERS | |
| 98 | Alopecia | FAERS: 8 | US FAERS | |
| 99 | Anxiety | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 100 | Hypersensitivity | FAERS: 8 | US FAERS | |
| 101 | Joint injury | FAERS: 8 | US FAERS | |
| 102 | Photophobia | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 103 | Product quality issue | FAERS: 8 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 104 | Blood glucose increased | FAERS: 7 | US FAERS | |
| 105 | Deafness Neurosensory | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 106 | Dementia | FAERS: 7 | US FAERS | |
| 107 | Drug prescribing error | FAERS: 7 | US FAERS | |
| 108 | Pericardial effusion | FAERS: 7 | US FAERS | |
| 109 | Pulmonary Embolism | FAERS: 7 | US FAERS | |
| 110 | Activities of daily living impaired | FAERS: 6 | US FAERS | |
| 111 | Asthma | FAERS: 6 | US FAERS | |
| 112 | Chills | FAERS: 6 | US FAERS | |
| 113 | Coronary Artery Disease | FAERS: 6 | US FAERS | |
| 114 | Deep Vein Thrombosis | FAERS: 6 | US FAERS | |
| 115 | Erection increased | FAERS: 6 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 116 | Extra dose administered | FAERS: 6 | US FAERS | |
| 117 | Flatulence | FAERS: 6 | US FAERS | |
| 118 | Food Poisoning | FAERS: 6 | US FAERS | |
| 119 | Gout | FAERS: 6 | US FAERS | |
| 120 | Musculoskeletal stiffness | FAERS: 6 | US FAERS | |
| 121 | Ocular vascular disorder | FAERS: 6 | US FAERS | |
| 122 | Pneumothorax | FAERS: 6 | US FAERS | |
| 123 | Prescription drug used without a prescription | FAERS: 6 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 124 | Product dose omission | FAERS: 6 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 125 | Pruritus | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 126 | Pulmonary arterial pressure increased | FAERS: 6 | US FAERS | |
| 127 | Pulmonary thrombosis | FAERS: 6 | US FAERS | |
| 128 | Respiratory arrest | FAERS: 6 | US FAERS | |
| 129 | Sciatica | FAERS: 6 | US FAERS | |
| 130 | Sudden death | FAERS: 6 | US FAERS | |
| 131 | Throat irritation | FAERS: 6 | US FAERS | |
| 132 | Cyanopsia | FAERS: 5 | US FAERS | |
| 133 | Fluid overload | FAERS: 5 | US FAERS | |
| 134 | Global Amnesia | FAERS: 5 | US FAERS | |
| 135 | Hemiparesis | FAERS: 5 | US FAERS | |
| 136 | Joint swelling | FAERS: 5 | US FAERS | |
| 137 | Macular degeneration | FAERS: 5 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 138 | Neuralgia | FAERS: 5 | US FAERS | |
| 139 | Osteomyelitis | FAERS: 5 | US FAERS | |
| 140 | Product prescribing error | FAERS: 5 | US FAERS | |
| 141 | Productive Cough | FAERS: 5 | US FAERS | |
| 142 | Pulmonary congestion | FAERS: 5 | US FAERS | |
| 143 | Retinal Vein Occlusion | FAERS: 5 | 16732206 | CTD US FAERS |
| 144 | Rheumatoid Arthritis | FAERS: 5 | US FAERS | |
| 145 | Tachycardia | FAERS: 5 | CTD US FAERS | |
| 146 | Abdominal Pain | FAERS: 4 | 18537952 | CTD US FAERS |
| 147 | Angina Pectoris | FAERS: 4 | US FAERS | |
| 148 | Ankle Fracture | FAERS: 4 | US FAERS | |
| 149 | Aphonia | FAERS: 4 | US FAERS | |
| 150 | Atrial Flutter | FAERS: 4 | US FAERS | |
| 151 | Blood glucose decreased | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 152 | Blood potassium decreased | FAERS: 4 | US FAERS | |
| 153 | Bronchopulmonary Aspergillosis | FAERS: 4 | US FAERS | |
| 154 | Cardiac infection | FAERS: 4 | US FAERS | |
| 155 | Cholelithiasis | FAERS: 4 | US FAERS | |
| 156 | Chorioretinal scar | FAERS: 4 | US FAERS | |
| 157 | Chromatopsia | FAERS: 4 | US FAERS | |
| 158 | Clostridium difficile infection | FAERS: 4 | US FAERS | |
| 159 | Cold sweat | FAERS: 4 | US FAERS | |
| 160 | Cystic Fibrosis | FAERS: 4 | 19747007 | CTD US FAERS |
| 161 | Drug abuse | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 162 | Emotional disorder | FAERS: 4 | US FAERS | |
| 163 | Eructation | FAERS: 4 | US FAERS | |
| 164 | Fracture | FAERS: 4 | US FAERS | |
| 165 | Ileus | FAERS: 4 | US FAERS | |
| 166 | Loss of personal independence in daily activities | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 167 | Musculoskeletal Pain | FAERS: 4 | US FAERS | |
| 168 | Nephrolithiasis | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 169 | Oxygen saturation abnormal | FAERS: 4 | US FAERS | |
| 170 | Pancreatitis | FAERS: 4 | US FAERS | |
| 171 | Product dispensing error | FAERS: 4 | US FAERS | |
| 172 | Pulmonary vascular disorder | FAERS: 4 | US FAERS | |
| 173 | Respiratory distress | FAERS: 4 | US FAERS | |
| 174 | Sneezing | FAERS: 4 | US FAERS | |
| 175 | Somnolence | FAERS: 4 | US FAERS | |
| 176 | Therapeutic product effect incomplete | FAERS: 4 Canada Vigilance: 20 | Canada Vigilance US FAERS | |
| 177 | Viral upper respiratory tract infection | FAERS: 4 | US FAERS | |
| 178 | Visual disturbance | FAERS: 4 | US FAERS | |
| 179 | Aortic Aneurysm | FAERS: 3 | US FAERS | |
| 180 | Ascites | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 181 | Back disorder | FAERS: 3 | US FAERS | |
| 182 | Blood creatinine increased | FAERS: 3 | US FAERS | |
| 183 | Blood pressure fluctuation | FAERS: 3 | US FAERS | |
| 184 | Blood sodium decreased | FAERS: 3 | US FAERS | |
| 185 | Blood sodium increased | FAERS: 3 | US FAERS | |
| 186 | Blood urea increased | FAERS: 3 | US FAERS | |
| 187 | Blood urine present | FAERS: 3 | US FAERS | |
| 188 | Bradycardia | FAERS: 3 | US FAERS | |
| 189 | Breast cancer recurrent | FAERS: 3 | US FAERS | |
| 190 | Bronchospasm | FAERS: 3 | US FAERS | |
| 191 | Carbon dioxide increased | FAERS: 3 | US FAERS | |
| 192 | Cholecystitis | FAERS: 3 | US FAERS | |
| 193 | Chronic respiratory failure | FAERS: 3 | US FAERS | |
| 194 | Colitis | FAERS: 3 | US FAERS | |
| 195 | Cystitis | FAERS: 3 | US FAERS | |
| 196 | Depressed Level of Consciousness | FAERS: 3 | US FAERS | |
| 197 | Depressed mood | FAERS: 3 | US FAERS | |
| 198 | Device related infection | FAERS: 3 | US FAERS | |
| 199 | Diplegia | FAERS: 3 | US FAERS | |
| 200 | Diplopia | FAERS: 3 | US FAERS | |
| 201 | Disease recurrence | FAERS: 3 | US FAERS | |
| 202 | Disorientation | FAERS: 3 | US FAERS | |
| 203 | Drug effective for unapproved indication | FAERS: 3 | US FAERS | |
| 204 | Dry age-related macular degeneration | FAERS: 3 | US FAERS | |
| 205 | Dysgeusia | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 206 | Dysuria | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 207 | Erectile dysfunction | FAERS: 3 |
8858389
9805292 9892316 10327382 10546163 10736486 11097980 11578679 12068841 12196335 12494295 14604312 14744177 15363994 15934858 15994112 16368379 17369119 17874315 18173768 18537952 19152827 21714539 27220266 | CTD US FAERS |
| 208 | Eye pain | FAERS: 3 | US FAERS | |
| 209 | Gastroenteritis | FAERS: 3 | US FAERS | |
| 210 | Hemiplegia | FAERS: 3 | US FAERS | |
| 211 | Hernia | FAERS: 3 | US FAERS | |
| 212 | Histamine level increased | FAERS: 3 | US FAERS | |
| 213 | Hypersomnia | FAERS: 3 | US FAERS | |
| 214 | Incorrect product storage | FAERS: 3 | US FAERS | |
| 215 | Laceration | FAERS: 3 | US FAERS | |
| 216 | Laryngitis | FAERS: 3 | US FAERS | |
| 217 | Mental impairment | FAERS: 3 | US FAERS | |
| 218 | Muscle strain | FAERS: 3 | US FAERS | |
| 219 | Musculoskeletal discomfort | FAERS: 3 | US FAERS | |
| 220 | Night sweats | FAERS: 3 | US FAERS | |
| 221 | Osteoporosis | FAERS: 3 | US FAERS | |
| 222 | Pancytopenia | FAERS: 3 | US FAERS | |
| 223 | Poor peripheral circulation | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 224 | Post procedural complication | FAERS: 3 | US FAERS | |
| 225 | Presyncope | FAERS: 3 | US FAERS | |
| 226 | Psoriasis | FAERS: 3 | US FAERS | |
| 227 | Rectal Prolapse | FAERS: 3 | US FAERS | |
| 228 | Respiratory tract congestion | FAERS: 3 | US FAERS | |
| 229 | Retinogram abnormal | FAERS: 3 | US FAERS | |
| 230 | Suicide attempt | FAERS: 3 | US FAERS | |
| 231 | Supraventricular tachycardia | FAERS: 3 | US FAERS | |
| 232 | Wheezing | FAERS: 3 | US FAERS | |
| 233 | treatment failure | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 234 | Abasia | FAERS: 2 | US FAERS | |
| 235 | Acute Coronary Syndrome | FAERS: 2 | US FAERS | |
| 236 | Alcohol interaction | FAERS: 2 | US FAERS | |
| 237 | Ammonia increased | FAERS: 2 | US FAERS | |
| 238 | Amphetamines positive | FAERS: 2 | US FAERS | |
| 239 | Blood cholesterol increased | FAERS: 2 | US FAERS | |
| 240 | Burning sensation | FAERS: 2 | US FAERS | |
| 241 | Cardiomegaly | FAERS: 2 | 15813973 30974023 | CTD US FAERS |
| 242 | Chemotherapy | FAERS: 2 | US FAERS | |
| 243 | Choking | FAERS: 2 | US FAERS | |
| 244 | Circumstance or information capable of leading to medication error | FAERS: 2 | US FAERS | |
| 245 | Completed Suicide | FAERS: 2 | US FAERS | |
| 246 | Constipation | FAERS: 2 | US FAERS | |
| 247 | Crying | FAERS: 2 | US FAERS | |
| 248 | Cyanosis | FAERS: 2 | US FAERS | |
| 249 | Disseminated Intravascular Coagulation | FAERS: 2 | US FAERS | |
| 250 | Diverticulitis | FAERS: 2 | US FAERS | |
| 251 | Drug administration error | FAERS: 2 | US FAERS | |
| 252 | Drug effect delayed | FAERS: 2 | US FAERS | |
| 253 | Drug exposure during pregnancy | FAERS: 2 | US FAERS | |
| 254 | Drug withdrawal syndrome | FAERS: 2 | US FAERS | |
| 255 | Dysarthria | FAERS: 2 | US FAERS | |
| 256 | Ear discomfort | FAERS: 2 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 257 | Failure to Thrive | FAERS: 2 | US FAERS | |
| 258 | Frostbite | FAERS: 2 | US FAERS | |
| 259 | Head discomfort | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 260 | Hepatitis | FAERS: 2 | US FAERS | |
| 261 | Hepatotoxicity | FAERS: 2 | US FAERS | |
| 262 | Hypertensive crisis | FAERS: 2 | US FAERS | |
| 263 | Hyperventilation | FAERS: 2 | US FAERS | |
| 264 | Hypoplastic Left Heart Syndrome | FAERS: 2 | US FAERS | |
| 265 | Increased upper airway secretion | FAERS: 2 | US FAERS | |
| 266 | Intentional dose omission | FAERS: 2 | US FAERS | |
| 267 | Intentional drug misuse | FAERS: 2 | US FAERS | |
| 268 | Intestinal Obstruction | FAERS: 2 | US FAERS | |
| 269 | Intracranial Aneurysm | FAERS: 2 | US FAERS | |
| 270 | Intracranial artery dissection | FAERS: 2 | US FAERS | |
| 271 | Joint Range of Motion Decreased | FAERS: 2 | US FAERS | |
| 272 | Lower respiratory tract infection | FAERS: 2 | US FAERS | |
| 273 | Lymphoma | FAERS: 2 | US FAERS | |
| 274 | Macular reflex abnormal | FAERS: 2 | US FAERS | |
| 275 | Myopia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 276 | Optic Atrophy | FAERS: 2 | US FAERS | |
| 277 | Pancreatic carcinoma | FAERS: 2 | US FAERS | |
| 278 | Platelet function test abnormal | FAERS: 2 | US FAERS | |
| 279 | Pleuritic pain | FAERS: 2 | US FAERS | |
| 280 | Procedural complication | FAERS: 2 | US FAERS | |
| 281 | Prostatic pain | FAERS: 2 | US FAERS | |
| 282 | Reaction to drug excipients | FAERS: 2 | US FAERS | |
| 283 | Reaction to excipient | FAERS: 2 | US FAERS | |
| 284 | Retinal Artery Occlusion | FAERS: 2 | 16732206 | CTD US FAERS |
| 285 | Retinal Detachment | FAERS: 2 | US FAERS | |
| 286 | Retinopathy of Prematurity | FAERS: 2 | US FAERS | |
| 287 | Right ventricular systolic pressure increased | FAERS: 2 | US FAERS | |
| 288 | Rotator cuff syndrome | FAERS: 2 | US FAERS | |
| 289 | Septic arthritis staphylococcal | FAERS: 2 | US FAERS | |
| 290 | Shock | FAERS: 2 | US FAERS | |
| 291 | Sinus Tachycardia | FAERS: 2 | US FAERS | |
| 292 | Sinus headache | FAERS: 2 | US FAERS | |
| 293 | Spinal column stenosis | FAERS: 2 | US FAERS | |
| 294 | Stool analysis abnormal | FAERS: 2 | US FAERS | |
| 295 | Tachyarrhythmia | FAERS: 2 | US FAERS | |
| 296 | Therapy cessation | FAERS: 2 | US FAERS | |
| 297 | Therapy non-responder | FAERS: 2 | US FAERS | |
| 298 | Traumatic Brain Injury | FAERS: 2 | US FAERS | |
| 299 | Trisomy 21 | FAERS: 2 | US FAERS | |
| 300 | Ulcer | FAERS: 2 | US FAERS | |
| 301 | Uterine Cancer | FAERS: 2 | US FAERS | |
| 302 | Ventilation perfusion mismatch | FAERS: 2 | US FAERS | |
| 303 | Vertigo | FAERS: 2 | US FAERS | |
| 304 | jaundice | FAERS: 2 | US FAERS | |
| 305 | Accidental death | FAERS: 1 | US FAERS | |
| 306 | Accidental exposure | FAERS: 1 | US FAERS | |
| 307 | Acute Chest Syndrome | FAERS: 1 | US FAERS | |
| 308 | Acute macular outer retinopathy | FAERS: 1 | US FAERS | |
| 309 | Ageusia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 310 | Agitation | FAERS: 1 | US FAERS | |
| 311 | Air Embolism | FAERS: 1 | US FAERS | |
| 312 | Alcohol abuse | FAERS: 1 | US FAERS | |
| 313 | Allergic reaction to excipient | FAERS: 1 | US FAERS | |
| 314 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 315 | Amblyopia | FAERS: 1 | US FAERS | |
| 316 | Aneurysm | FAERS: 1 | US FAERS | |
| 317 | Anginal equivalent | FAERS: 1 | US FAERS | |
| 318 | Angioedema | FAERS: 1 | US FAERS | |
| 319 | Anti factor VIII antibody test | FAERS: 1 | US FAERS | |
| 320 | Aortic surgery | FAERS: 1 | US FAERS | |
| 321 | Apallic syndrome | FAERS: 1 | US FAERS | |
| 322 | Arterial thrombosis | FAERS: 1 | US FAERS | |
| 323 | Asphyxia | FAERS: 1 | US FAERS | |
| 324 | Autoimmune lung disease | FAERS: 1 | US FAERS | |
| 325 | Bacterial test positive | FAERS: 1 | US FAERS | |
| 326 | Balanitis | FAERS: 1 | US FAERS | |
| 327 | Basal cell carcinoma | FAERS: 1 | US FAERS | |
| 328 | Basilar artery thrombosis | FAERS: 1 | US FAERS | |
| 329 | Biliary cirrhosis | FAERS: 1 | US FAERS | |
| 330 | Bilirubin conjugated increased | FAERS: 1 | US FAERS | |
| 331 | Bipolar Disorder | FAERS: 1 | US FAERS | |
| 332 | Bladder Neoplasm | FAERS: 1 | US FAERS | |
| 333 | Blood albumin abnormal | FAERS: 1 | US FAERS | |
| 334 | Blood albumin decreased | FAERS: 1 | US FAERS | |
| 335 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 336 | Blood chloride decreased | FAERS: 1 | US FAERS | |
| 337 | Blood count abnormal | FAERS: 1 | US FAERS | |
| 338 | Blood creatine phosphokinase decreased | FAERS: 1 | US FAERS | |
| 339 | Blood glucose abnormal | FAERS: 1 | US FAERS | |
| 340 | Blood iron decreased | FAERS: 1 | US FAERS | |
| 341 | Blood lactate dehydrogenase increased | FAERS: 1 | US FAERS | |
| 342 | Blood magnesium decreased | FAERS: 1 | US FAERS | |
| 343 | Blood potassium increased | FAERS: 1 | US FAERS | |
| 344 | Blood testosterone decreased | FAERS: 1 | US FAERS | |
| 345 | Bone pain | FAERS: 1 | US FAERS | |
| 346 | Brain Death | FAERS: 1 | US FAERS | |
| 347 | Brain Hypoxia | FAERS: 1 | US FAERS | |
| 348 | Brain natriuretic peptide increased | FAERS: 1 | US FAERS | |
| 349 | Breast tenderness | FAERS: 1 | US FAERS | |
| 350 | Bursitis | FAERS: 1 | US FAERS | |
| 351 | Cardiac Flutter | FAERS: 1 | US FAERS | |
| 352 | Cardiac Tamponade | FAERS: 1 | US FAERS | |
| 353 | Cardiac discomfort | FAERS: 1 | US FAERS | |
| 354 | Cardiac sarcoidosis | FAERS: 1 | US FAERS | |
| 355 | Cartilage injury | FAERS: 1 | US FAERS | |
| 356 | Cell marker increased | FAERS: 1 | US FAERS | |
| 357 | Central Cord Syndrome | FAERS: 1 | US FAERS | |
| 358 | Cerebellar infarction | FAERS: 1 | US FAERS | |
| 359 | Cerebrovascular Insufficiency | FAERS: 1 | US FAERS | |
| 360 | Choking sensation | FAERS: 1 | US FAERS | |
| 361 | Cholecystitis infective | FAERS: 1 | US FAERS | |
| 362 | Cholestasis | FAERS: 1 | US FAERS | |
| 363 | Chromaturia | FAERS: 1 | US FAERS | |
| 364 | Clostridium difficile colitis | FAERS: 1 | US FAERS | |
| 365 | Clumsiness | FAERS: 1 | US FAERS | |
| 366 | Complication associated with device | FAERS: 1 | US FAERS | |
| 367 | Conjunctivitis | FAERS: 1 | US FAERS | |
| 368 | Contraindicated drug administered | FAERS: 1 | US FAERS | |
| 369 | Contraindicated product administered | FAERS: 1 | US FAERS | |
| 370 | Coronary artery dilatation | FAERS: 1 | US FAERS | |
| 371 | Cyst | FAERS: 1 | US FAERS | |
| 372 | Delirium | FAERS: 1 | US FAERS | |
| 373 | Dependence on enabling machine or device | FAERS: 1 | US FAERS | |
| 374 | Dependence | FAERS: 1 | US FAERS | |
| 375 | Deposit eye | FAERS: 1 | US FAERS | |
| 376 | Device defective | FAERS: 1 | US FAERS | |
| 377 | Diabetic Retinopathy | FAERS: 1 | US FAERS | |
| 378 | Diabetic ulcer | FAERS: 1 | US FAERS | |
| 379 | Dialysis related complication | FAERS: 1 | US FAERS | |
| 380 | Discomfort | FAERS: 1 | US FAERS | |
| 381 | Disease complication | FAERS: 1 | US FAERS | |
| 382 | Drug screen positive | FAERS: 1 | US FAERS | |
| 383 | Dry gangrene | FAERS: 1 | US FAERS | |
| 384 | Dry skin | FAERS: 1 | US FAERS | |
| 385 | Dyschromatopsia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 386 | Dysgraphia | FAERS: 1 | US FAERS | |
| 387 | Ear congestion | FAERS: 1 | US FAERS | |
| 388 | Eczema | FAERS: 1 | US FAERS | |
| 389 | Electrocardiogram abnormal | FAERS: 1 | US FAERS | |
| 390 | Electrolyte imbalance | FAERS: 1 | US FAERS | |
| 391 | Endocarditis | FAERS: 1 | US FAERS | |
| 392 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 393 | Erythropsia | FAERS: 1 | US FAERS | |
| 394 | Erythrosis | FAERS: 1 | US FAERS | |
| 395 | Expired drug administered | FAERS: 1 | US FAERS | |
| 396 | Exudative retinopathy | FAERS: 1 | US FAERS | |
| 397 | Eye irritation | FAERS: 1 | US FAERS | |
| 398 | Eye opacity | FAERS: 1 | US FAERS | |
| 399 | Eyelid Function Disorder | FAERS: 1 | US FAERS | |
| 400 | Feeling Cold | FAERS: 1 | US FAERS | |
| 401 | Fibrosis | FAERS: 1 | US FAERS | |
| 402 | Foreign body sensation in eyes | FAERS: 1 | US FAERS | |
| 403 | Gait inability | FAERS: 1 | US FAERS | |
| 404 | Gangrene | FAERS: 1 | US FAERS | |
| 405 | Gastric infection | FAERS: 1 | US FAERS | |
| 406 | General physical condition abnormal | FAERS: 1 | US FAERS | |
| 407 | Glaucoma | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 408 | Glossitis | FAERS: 1 | US FAERS | |
| 409 | Graft infection | FAERS: 1 | US FAERS | |
| 410 | Hand-eye coordination impaired | FAERS: 1 | US FAERS | |
| 411 | Harlequin skin reaction | FAERS: 1 | US FAERS | |
| 412 | Hepatic Infection | FAERS: 1 | US FAERS | |
| 413 | Hepatic congestion | FAERS: 1 | US FAERS | |
| 414 | Hepatomegaly | FAERS: 1 | 30026087 | CTD US FAERS |
| 415 | Hepatopulmonary Syndrome | FAERS: 1 | US FAERS | |
| 416 | Hydrocephalus | FAERS: 1 | US FAERS | |
| 417 | Hydrophobia | FAERS: 1 | US FAERS | |
| 418 | Hypocoagulable state | FAERS: 1 | US FAERS | |
| 419 | Hypokinesia | FAERS: 1 | US FAERS | |
| 420 | Hypomania | FAERS: 1 | US FAERS | |
| 421 | Hysterectomy | FAERS: 1 | US FAERS | |
| 422 | Immobile | FAERS: 1 | US FAERS | |
| 423 | Impaired gastric emptying | FAERS: 1 | US FAERS | |
| 424 | Inappropriate affect | FAERS: 1 | US FAERS | |
| 425 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 426 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 427 | Inflammation | FAERS: 1 | US FAERS | |
| 428 | Intentional misuse | FAERS: 1 | US FAERS | |
| 429 | Intestinal Perforation | FAERS: 1 | US FAERS | |
| 430 | Labile blood pressure | FAERS: 1 | US FAERS | |
| 431 | Lacrimation decreased | FAERS: 1 | US FAERS | |
| 432 | Left Ventricular Hypertrophy | FAERS: 1 | US FAERS | |
| 433 | Lens dislocation | FAERS: 1 | US FAERS | |
| 434 | Lentigo | FAERS: 1 | US FAERS | |
| 435 | Leukocytoclastic vasculitis | FAERS: 1 | US FAERS | |
| 436 | Leukoplakia | FAERS: 1 | US FAERS | |
| 437 | Limb injury | FAERS: 1 | US FAERS | |
| 438 | Lip swelling | FAERS: 1 | US FAERS | |
| 439 | Lower respiratory tract infection viral | FAERS: 1 | US FAERS | |
| 440 | Lymphocyte count decreased | FAERS: 1 | US FAERS | |
| 441 | Malabsorption | FAERS: 1 | US FAERS | |
| 442 | Malignant neoplasm progression | FAERS: 1 | US FAERS | |
| 443 | Malnutrition | FAERS: 1 | US FAERS | |
| 444 | Marasmus | FAERS: 1 | US FAERS | |
| 445 | Maternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 446 | Medical device removal | FAERS: 1 | US FAERS | |
| 447 | Menorrhagia | FAERS: 1 | US FAERS | |
| 448 | Mesothelioma | FAERS: 1 | US FAERS | |
| 449 | Middle insomnia | FAERS: 1 | US FAERS | |
| 450 | Miliaria | FAERS: 1 | US FAERS | |
| 451 | Monocyte count increased | FAERS: 1 | US FAERS | |
| 452 | Mood swings | FAERS: 1 | US FAERS | |
| 453 | Mouth swelling | FAERS: 1 | US FAERS | |
| 454 | Muscle tightness | FAERS: 1 | US FAERS | |
| 455 | Mutism | FAERS: 1 | US FAERS | |
| 456 | Neonatal hypotension | FAERS: 1 | US FAERS | |
| 457 | Neurological examination abnormal | FAERS: 1 | US FAERS | |
| 458 | No adverse effect | FAERS: 1 | US FAERS | |
| 459 | Nocardia sepsis | FAERS: 1 | US FAERS | |
| 460 | Nodular melanoma | FAERS: 1 | US FAERS | |
| 461 | Obesity | FAERS: 1 | US FAERS | |
| 462 | Oliguria | FAERS: 1 | US FAERS | |
| 463 | Optic Neuritis | FAERS: 1 | US FAERS | |
| 464 | Optic nerve cup/disc ratio decreased | FAERS: 1 | US FAERS | |
| 465 | Oral pain | FAERS: 1 | US FAERS | |
| 466 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 467 | Otitis Media | FAERS: 1 | US FAERS | |
| 468 | Oxygen consumption decreased | FAERS: 1 | US FAERS | |
| 469 | Pancreatic Cyst | FAERS: 1 | US FAERS | |
| 470 | Paranasal sinus discomfort | FAERS: 1 | US FAERS | |
| 471 | Peripheral arterial occlusive disease | FAERS: 1 | US FAERS | |
| 472 | Peritonitis | FAERS: 1 | US FAERS | |
| 473 | Pertussis | FAERS: 1 | US FAERS | |
| 474 | Petechiae | FAERS: 1 | US FAERS | |
| 475 | Phimosis | FAERS: 1 | US FAERS | |
| 476 | Polymyositis | FAERS: 1 | US FAERS | |
| 477 | Poor quality sleep | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 478 | Post procedural infection | FAERS: 1 | US FAERS | |
| 479 | Posterior reversible encephalopathy syndrome | FAERS: 1 | US FAERS | |
| 480 | Postoperative fever | FAERS: 1 | US FAERS | |
| 481 | Postoperative respiratory distress | FAERS: 1 | US FAERS | |
| 482 | Prerenal failure | FAERS: 1 | US FAERS | |
| 483 | Prescribed underdose | FAERS: 1 | US FAERS | |
| 484 | Product administration error | FAERS: 1 | US FAERS | |
| 485 | Product counterfeit | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 486 | Product formulation issue | FAERS: 1 | US FAERS | |
| 487 | Product label confusion | FAERS: 1 | US FAERS | |
| 488 | Product label issue | FAERS: 1 | US FAERS | |
| 489 | Product preparation error | FAERS: 1 | US FAERS | |
| 490 | Promotion of peripheral circulation | FAERS: 1 | US FAERS | |
| 491 | Pulmonary vascular resistance abnormality | FAERS: 1 | US FAERS | |
| 492 | Quadriparesis | FAERS: 1 | US FAERS | |
| 493 | Respiratory syncytial virus bronchiolitis | FAERS: 1 | US FAERS | |
| 494 | Restless Legs Syndrome | FAERS: 1 | US FAERS | |
| 495 | Restlessness | FAERS: 1 | US FAERS | |
| 496 | Retching | FAERS: 1 | US FAERS | |
| 497 | Rhinitis | FAERS: 1 | US FAERS | |
| 498 | Sarcoidosis | FAERS: 1 | US FAERS | |
| 499 | Scab | FAERS: 1 | US FAERS | |
| 500 | Scotoma | FAERS: 1 | US FAERS | |
| 501 | Sexual Dysfunction | FAERS: 1 | US FAERS | |
| 502 | Sexual abuse | FAERS: 1 | US FAERS | |
| 503 | Skin lesion | FAERS: 1 | US FAERS | |
| 504 | Skin reaction | FAERS: 1 | US FAERS | |
| 505 | Skin tightness | FAERS: 1 | US FAERS | |
| 506 | Soft tissue necrosis | FAERS: 1 | US FAERS | |
| 507 | Solar lentigo | FAERS: 1 | US FAERS | |
| 508 | Spirometry abnormal | FAERS: 1 | US FAERS | |
| 509 | Splenic Infarction | FAERS: 1 | US FAERS | |
| 510 | Stomatitis | FAERS: 1 | US FAERS | |
| 511 | Strabismus | FAERS: 1 | US FAERS | |
| 512 | Stridor | FAERS: 1 | US FAERS | |
| 513 | Sudden Cardiac Death | FAERS: 1 | US FAERS | |
| 514 | Systolic dysfunction | FAERS: 1 | US FAERS | |
| 515 | Therapeutic product effect decreased | FAERS: 1 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 516 | Therapeutic product effect delayed | FAERS: 1 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 517 | Therapeutic reaction time decreased | FAERS: 1 | US FAERS | |
| 518 | Thermal burn | FAERS: 1 | US FAERS | |
| 519 | Thirst | FAERS: 1 | US FAERS | |
| 520 | Throat cancer | FAERS: 1 | US FAERS | |
| 521 | Toxic Shock Syndrome | FAERS: 1 | US FAERS | |
| 522 | Transaminases increased | FAERS: 1 | US FAERS | |
| 523 | Transcription medication error | FAERS: 1 | US FAERS | |
| 524 | Trismus | FAERS: 1 | US FAERS | |
| 525 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 526 | Unwanted pregnancy | FAERS: 1 | US FAERS | |
| 527 | Urinary tract obstruction | FAERS: 1 | US FAERS | |
| 528 | Urticaria | FAERS: 1 | US FAERS | |
| 529 | Uveitis | FAERS: 1 | US FAERS | |
| 530 | Vascular occlusion | FAERS: 1 | US FAERS | |
| 531 | Vascular stenosis | FAERS: 1 | US FAERS | |
| 532 | Vena cava injury | FAERS: 1 | US FAERS | |
| 533 | Venous Thrombosis | FAERS: 1 | US FAERS | |
| 534 | Ventricular Fibrillation | FAERS: 1 | US FAERS | |
| 535 | Ventricular arrhythmia | FAERS: 1 | US FAERS | |
| 536 | Vertebral Artery Dissection | FAERS: 1 | US FAERS | |
| 537 | Vocal Cord Paralysis | FAERS: 1 | US FAERS | |
| 538 | Vulvovaginal pruritus | FAERS: 1 | US FAERS | |
| 539 | Walking distance test abnormal | FAERS: 1 | US FAERS | |
| 540 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 541 | Wrong technique in product usage process | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 542 | Abortion, Habitual | 19912049 | CTD | |
| 543 | Amnesia, Transient Global | 12221181 | CTD | |
| 544 | Anhedonia | Canada Vigilance: 1 | Canada Vigilance | |
| 545 | Bundle-Branch Block | 10475830 | CTD | |
| 546 | Cardiomyopathies | 15811867 | CTD | |
| 547 | Cerebral Hemorrhage | 11599452 | CTD | |
| 548 | Chemical and Drug Induced Liver Injury | 30974023 | CTD | |
| 549 | Cholestasis, Extrahepatic | 30026087 | CTD | |
| 550 | Cluster Headache | 16674772 | CTD | |
| 551 | Coronary Stenosis | 11113052 | CTD | |
| 552 | Coronary Thrombosis | 16858176 | CTD | |
| 553 | Counterfeit product administered | Canada Vigilance: 6 | Canada Vigilance | |
| 554 | Drug Dependence | Canada Vigilance: 1 | Canada Vigilance | |
| 555 | Emotional distress | Canada Vigilance: 1 | Canada Vigilance | |
| 556 | Heart failure | 18667251 | CTD | |
| 557 | Hemianopsia | 18292633 | CTD | |
| 558 | Hepatic Insufficiency | 30026087 | CTD | |
| 559 | Hyperglycemia | 19845545 26006044 | CTD | |
| 560 | Hyperinsulinism | 19845545 | CTD | |
| 561 | Hypertriglyceridemia | 19845545 | CTD | |
| 562 | Inappropriate schedule of product administration | Canada Vigilance: 1 | Canada Vigilance | |
| 563 | Infarction, Middle Cerebral Artery | 18290852 | CTD | |
| 564 | Intestinal Pseudo-Obstruction | Canada Vigilance: 1 | Canada Vigilance | |
| 565 | Kidney Diseases | 19152827 | CTD | |
| 566 | Meconium Aspiration Syndrome | 11956051 | CTD | |
| 567 | Meniscus injury | Canada Vigilance: 1 | Canada Vigilance | |
| 568 | Migraine Disorders | 12477710 | CTD | |
| 569 | Myocardial Ischemia | 11113052 11140290 | CTD | |
| 570 | Myocardial Reperfusion Injury | 12181158 | CTD | |
| 571 | Necrosis | 15813973 20583517 | CTD | |
| 572 | Negative thoughts | Canada Vigilance: 1 | Canada Vigilance | |
| 573 | Neoplasms, Experimental | 17101732 | CTD | |
| 574 | Optic Neuropathy, Ischemic | CTD | ||
| 575 | Penile curvature | Canada Vigilance: 1 | Canada Vigilance | |
| 576 | Postoperative Complications | 20583517 | CTD | |
| 577 | Product administered to patient of inappropriate age | Canada Vigilance: 2 | Canada Vigilance | |
| 578 | Product complaint | Canada Vigilance: 5 | Canada Vigilance | |
| 579 | Product taste abnormal | Canada Vigilance: 2 | Canada Vigilance | |
| 580 | Prostatic Neoplasms | 20884855 | CTD | |
| 581 | Pulmonary Edema | 30974023 | CTD | |
| 582 | Quality of life decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 583 | Seizures | 27220266 | CTD | |
| 584 | Skin Manifestations | 20583517 | CTD | |
| 585 | Spermatic Cord Torsion | 18265987 | CTD | |
| 586 | Stomach Diseases | 16113693 | CTD | |
| 587 | Subarachnoid Hemorrhage | 20379474 | CTD | |
| 588 | Substance Withdrawal Syndrome | 11377161 15639152 16917115 | CTD | |
| 589 | Tachycardia, Ventricular | 17697313 | CTD | |
| 590 | Therapeutic product effect increased | Canada Vigilance: 1 | Canada Vigilance | |
| 591 | Therapeutic product ineffective | Canada Vigilance: 3 | Canada Vigilance | |
| 592 | Ventricular Dysfunction, Left | 20884855 | CTD |
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