MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Avulsion fracture

(UMLS:C0332758)

Definition:: Tearing away of the CORTICAL BONE fragment at the location of a strong ligament or tendon attachment. The bone fragment detachment site often occurs near a soft site (e.g., GROWTH PLATE) at the base where LIGAMENTS; TENDONS; or JOINT CAPSULES attach. In younger patients it is most often caused by a sudden forceful pull on a tendon in the opposite direction of the bone movement. In the elderly it is associated with osteoporotic INSUFFICIENCY FRACTURES.
UMLS ID:: C0332758
MeSH ID:: D000071562

Classification:

Name:

Wounds and Injuries
MeSH Tree Number(s):: C26.404.038

Synonym(s)

Avulsion fracture

Avulsion

[Q] Avulsion

avulsion fracture

avulsion fractures

avulsions

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Alendronate	FAERS: 9	US FAERS
2	Octreotide	FAERS: 5	US FAERS
3	Fingolimod Hydrochloride	FAERS: 4	US FAERS
4	NuvaRing	FAERS: 4	US FAERS
5	Ciprofloxacin	FAERS: 2	US FAERS
6	Isotretinoin	FAERS: 2	US FAERS
7	montelukast	FAERS: 2	US FAERS
8	Citalopram	FAERS: 1	US FAERS
9	Clozapine	FAERS: 1	US FAERS
10	Letrozole	FAERS: 1	US FAERS
11	Medroxyprogesterone Acetate	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
12	Moxifloxacin	FAERS: 1	US FAERS
13	Ruxolitinib phosphate	FAERS: 1	US FAERS
14	Teriparatide	FAERS: 1	US FAERS
15	Tiotropium Bromide	FAERS: 1	US FAERS
16	rotigotine	FAERS: 1	US FAERS
17	tofacitinib	FAERS: 1	US FAERS
18	Baclofen		OFFSIDES
19	Chlorhexidine		OFFSIDES
20	Lamotrigine		OFFSIDES
21	Pamidronate		OFFSIDES
22	Zoledronic Acid		OFFSIDES
23	chlorhexidine gluconate		OFFSIDES
24	nefazodone		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Fractures, Closed	42.9%
2	Pathological fracture	42.9%
3	Ankle Fracture	42.9%
4	Compression fracture	42.9%
5	Osteoporotic Fractures	42.9%
6	Femoral Fractures	38.1%
7	Tibial Fractures	38.1%
8	Spinal Fractures	34.9%
9	Pseudarthrosis	31%
10	Hip Fractures	27.6%
11	Frostbite	25%
12	Athletic Injuries	23.1%
13	Hand Injuries	23.1%
14	Soft Tissue Injuries	23.1%
15	Sprain	23.1%
16	Sprains and Strains	23.1%
17	Tendon Injuries	23.1%
18	Laceration	23.1%
19	Wounds, Penetrating	23.1%
20	Heat Cramps	23.1%
21	Rupture	23.1%
22	Crush syndrome	19%
23	Chilblains	16.3%
24	Trauma, Nervous System	15.8%
25	Bites and Stings	15%
26	Extravasation of Diagnostic and Therapeutic Materials	15%
27	Vascular System Injuries	15%
28	Tympanic Membrane Perforation	15%
29	Tooth Injuries	15%
30	Asphyxia	14.6%
31	Esophageal Perforation	14.6%
32	Shock, Traumatic	14.6%
33	Self Mutilation	14.5%
34	Human Bite	14.3%
35	Contusions	14.3%
36	Decompression Sickness	14.3%
37	Finger Injuries	14.3%
38	Flail Chest	14.3%
39	Heart Injuries	14.3%
40	Heat Exhaustion	14.3%
41	Heat Stroke	14.3%
42	Knee Injuries	14.3%
43	Foot Injuries	14.3%
44	Decapitation	14.3%
45	Hip Dislocation	14%
46	Shoulder Dislocation	14%
47	Splenic Rupture	14%
48	Hip Dysplasia	14%
49	Iliotibial Band Syndrome	13.6%
50	Spinal Cord Injuries	10.9%
51	Drowning	10.7%
52	Eye Burns	10.5%
53	Smoke Inhalation Injury	10.3%
54	Splenosis	10.1%
55	Craniocerebral Trauma	9.5%
56	Tendinitis	9.5%
57	Lung Injury	9.5%
58	Tendinopathy	9.5%
59	Foreign-Body Reaction	9.3%
60	Insect Bites and Stings	9.3%
61	Paralysis, Obstetric	9.3%
62	Sunburn	9.3%
63	Tooth Avulsion	9.3%
64	Conus Medullaris Syndrome	9.3%
65	Near Drowning	9.2%
66	Osteoradionecrosis	9.2%
67	Radiation injury	8.3%
68	Brain Concussion	7.2%
69	Neoplasms, Radiation-Induced	7.2%
70	Peripheral Nerve Injuries	7%
71	Medial Tibial Stress Syndrome	7%
72	Brain Contusion	6.9%
73	Uterine Rupture	6.8%
74	Central Cord Syndrome	6.8%
75	Facial Injuries	6.8%
76	Granuloma, Foreign-Body	6.8%
77	Enthesopathy	6.8%
78	Uterine Perforation	6.7%
79	Cardiotoxicity	5.6%
80	Leukemia, Radiation-Induced	5.5%
81	Radiation Pneumonitis	5.4%
82	Radiation Fibrosis	5.4%
83	Aortic Rupture	5.4%
84	Brain Injuries	5.1%
85	Coma, Post-Head Injury	5%
86	Carpal Tunnel Syndrome	5%
87	Abnormalities, Radiation-Induced	4.5%
88	Radiation Injuries, Experimental	4.4%
89	Eye Injuries	4.4%
90	Brain Injuries, Diffuse	4.1%
91	Traumatic Brain Injury	4.1%
92	Cubital Tunnel Syndrome	4.1%
93	Brain Hemorrhage, Traumatic	4.1%
94	Diffuse Axonal Injury	3.7%
95	Pneumocephalus	3.4%
96	Olfactory Nerve Injuries	3.3%
97	Cerebrospinal Fluid Otorrhea	3.3%
98	Cerebrospinal Fluid Rhinorrhea	3.3%
99	Vertebral Artery Dissection	3.3%
100	Epilepsy, Post-Traumatic	3.3%
101	Corneal Scar	3.1%
102	Carotid Artery Injuries	2.8%
103	Corneal Perforation	2.8%
104	Facial Nerve Injuries	2.8%
105	Hematoma, Subdural	2.3%
106	Hematoma, Epidural, Cranial	2.3%
107	Hematoma, Subdural, Intracranial	2.1%
108	Hematoma, Subdural, Chronic	2.1%
109	Hematoma, Subdural, Acute	2.1%
110	Subarachnoid Hemorrhage, Traumatic	2%
111	Carotid Artery, Internal, Dissection	2%

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