Ethinyl Estradiol-Norgestrel Combination
(ORKBYCQJWQBPFG-WOMZHKBXSA-N)
Structure
- SMILES
- C#C[C@]1(O)CC[C@@H]2[C@]1(CC)CC[C@H]1[C@H]2CCC2=CC(=O)CC[C@H]12.C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCc2c1ccc(c2)O
- Molecular Formula:
- C41H52O4
- Molecular Weight:
- 608.849
- Log P:
- 7.4952
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 3
- TPSA:
- 77.76
- CAS Number(s):
- 8056-51-7; 39366-37-5
Synonym(s)
1.
Ethinyl Estradiol-Norgestrel Combination
2.
Norgestrel-Ethinyl Estradiol Combination
3.
Adepal
4.
Anteovin
5.
Eugynon
6.
Gravistat
7.
Leios
8.
Minisiston
9.
Nordette
10.
Ovidon
11.
Ovral
12.
Pearl Oral Contraceptive
13.
Rigevidon
14.
Sequostat
15.
Stediril
16.
Trigynon
17.
Trinordiol
18.
Triphasil
19.
Triquilar
20.
Trisiston
21.
Trisistone R
22.
Trisistone-R
23.
Combination, Ethinyl Estradiol-Norgestrel
24.
Combination, Norgestrel-Ethinyl Estradiol
25.
Contraceptive, Pearl Oral
26.
Estradiol Combination, Norgestrel-Ethinyl
27.
Estradiol-Norgestrel Combination, Ethinyl
28.
Ethinyl Estradiol Norgestrel Combination
29.
Norgestrel Ethinyl Estradiol Combination
30.
Oral Contraceptive, Pearl
31.
TrisistoneR
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 349 Canada Vigilance: 73 | Canada Vigilance US FAERS | |
| 2 | Product quality issue | FAERS: 250 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 3 | Metrorrhagia | FAERS: 167 Canada Vigilance: 23 | CTD Canada Vigilance US FAERS | |
| 4 | Menorrhagia | FAERS: 73 Canada Vigilance: 3 | 4263090 | CTD Canada Vigilance US FAERS |
| 5 | Headache | FAERS: 72 Canada Vigilance: 14 | CTD Canada Vigilance US FAERS | |
| 6 | Pulmonary Embolism | FAERS: 70 Canada Vigilance: 11 | 2010744 | CTD Canada Vigilance US FAERS |
| 7 | Inappropriate schedule of drug administration | FAERS: 62 | US FAERS | |
| 8 | Nausea | FAERS: 60 Canada Vigilance: 26 | CTD Canada Vigilance US FAERS | |
| 9 | Vomiting | FAERS: 47 Canada Vigilance: 11 | 1183625 6524863 | CTD Canada Vigilance US FAERS |
| 10 | Anxiety | FAERS: 44 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 11 | Malaise | FAERS: 43 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 12 | Pregnancy on oral contraceptive | FAERS: 39 Canada Vigilance: 25 | Canada Vigilance US FAERS | |
| 13 | Drug dose omission | FAERS: 38 | US FAERS | |
| 14 | Feeling abnormal | FAERS: 35 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 15 | Abdominal Pain | FAERS: 34 Canada Vigilance: 4 | 4701037 6524863 | CTD Canada Vigilance US FAERS |
| 16 | Mood swings | FAERS: 33 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 17 | Abnormal withdrawal bleeding | FAERS: 32 | US FAERS | |
| 18 | Deep Vein Thrombosis | FAERS: 31 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 19 | Dizziness | FAERS: 29 Canada Vigilance: 4 | 8403908 | CTD Canada Vigilance US FAERS |
| 20 | Drug exposure during pregnancy | FAERS: 27 | US FAERS | |
| 21 | Fatigue | FAERS: 25 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 22 | Acne | FAERS: 23 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 23 | Thrombosis | FAERS: 21 Canada Vigilance: 3 | 4823354 | CTD Canada Vigilance US FAERS |
| 24 | Product substitution issue | FAERS: 20 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 25 | Asthenia | FAERS: 18 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 26 | Cerebrovascular accident | FAERS: 18 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 27 | Chest Pain | FAERS: 18 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 28 | Maternal exposure during pregnancy | FAERS: 18 | US FAERS | |
| 29 | Pain | FAERS: 18 | US FAERS | |
| 30 | Alopecia | FAERS: 17 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 31 | Drug ineffective for unapproved indication | FAERS: 17 | US FAERS | |
| 32 | Urinary tract infection | FAERS: 16 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 33 | Breast tenderness | FAERS: 15 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 34 | Pharmaceutical product complaint | FAERS: 15 | US FAERS | |
| 35 | Weight decreased | FAERS: 15 | US FAERS | |
| 36 | Cerebral Infarction | FAERS: 14 | US FAERS | |
| 37 | Circumstance or information capable of leading to medication error | FAERS: 11 | US FAERS | |
| 38 | Hormone level abnormal | FAERS: 11 | US FAERS | |
| 39 | Hypersensitivity | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 40 | Urticaria | FAERS: 11 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 41 | Visual Impairment | FAERS: 11 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 42 | Alanine Aminotransferase Increased | FAERS: 10 | US FAERS | |
| 43 | Arthralgia | FAERS: 10 | US FAERS | |
| 44 | Ectopic Pregnancy | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 45 | Product use in unapproved indication | FAERS: 10 | US FAERS | |
| 46 | Product use issue | FAERS: 10 | US FAERS | |
| 47 | Back Pain | FAERS: 9 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 48 | Emotional disorder | FAERS: 9 | US FAERS | |
| 49 | Pruritus | FAERS: 9 Canada Vigilance: 1 | 4272507 | CTD Canada Vigilance US FAERS |
| 50 | Cardiac Arrest | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 51 | Maternal exposure timing unspecified | FAERS: 8 | US FAERS | |
| 52 | Medication Error | FAERS: 8 | US FAERS | |
| 53 | No adverse event | FAERS: 8 | US FAERS | |
| 54 | Chest discomfort | FAERS: 7 | US FAERS | |
| 55 | Cholelithiasis | FAERS: 7 | US FAERS | |
| 56 | Crying | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 57 | Premenstrual syndrome | FAERS: 7 | 4263090 | CTD US FAERS |
| 58 | Pulmonary thrombosis | FAERS: 7 | US FAERS | |
| 59 | Somnolence | FAERS: 7 | US FAERS | |
| 60 | Abdominal discomfort | FAERS: 6 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 61 | Anorexia | FAERS: 6 | US FAERS | |
| 62 | Aspartate Aminotransferase Increased | FAERS: 6 | US FAERS | |
| 63 | Blood cholesterol increased | FAERS: 6 | US FAERS | |
| 64 | Drug administration error | FAERS: 6 | US FAERS | |
| 65 | Drug exposure before pregnancy | FAERS: 6 | US FAERS | |
| 66 | Epilepsy | FAERS: 6 | US FAERS | |
| 67 | Phlebitis | FAERS: 6 | US FAERS | |
| 68 | Pregnancy | FAERS: 6 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 69 | Product packaging issue | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 70 | Syncope | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 71 | Toxic Epidermal Necrolysis | FAERS: 6 | US FAERS | |
| 72 | Tremor | FAERS: 6 | US FAERS | |
| 73 | Abasia | FAERS: 5 | US FAERS | |
| 74 | Acute myocardial infarction | FAERS: 5 | US FAERS | |
| 75 | Anger | FAERS: 5 | US FAERS | |
| 76 | Constipation | FAERS: 5 | US FAERS | |
| 77 | Diabetes Mellitus | FAERS: 5 | US FAERS | |
| 78 | Flatulence | FAERS: 5 | US FAERS | |
| 79 | Hemiplegia | FAERS: 5 | US FAERS | |
| 80 | Hepatitis | FAERS: 5 | US FAERS | |
| 81 | Intentional drug misuse | FAERS: 5 | US FAERS | |
| 82 | Joint injury | FAERS: 5 | US FAERS | |
| 83 | Myocardial Infarction | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 84 | Therapeutic response unexpected with drug substitution | FAERS: 5 | US FAERS | |
| 85 | Thrombophlebitis | FAERS: 5 Canada Vigilance: 1 | 1183625 6403704 | CTD Canada Vigilance US FAERS |
| 86 | Vaginal Discharge | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 87 | Wrong technique in product usage process | FAERS: 5 | US FAERS | |
| 88 | Asthma | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 89 | Carotid Artery Thrombosis | FAERS: 4 | US FAERS | |
| 90 | Cerebral Thrombosis | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 91 | Cystitis | FAERS: 4 | US FAERS | |
| 92 | Depressed mood | FAERS: 4 | US FAERS | |
| 93 | Diplopia | FAERS: 4 | US FAERS | |
| 94 | Epigastric discomfort | FAERS: 4 | US FAERS | |
| 95 | Gastroenteritis | FAERS: 4 | US FAERS | |
| 96 | Hypersomnia | FAERS: 4 | US FAERS | |
| 97 | Hypothyroidism | FAERS: 4 | US FAERS | |
| 98 | Irritable Bowel Syndrome | FAERS: 4 | US FAERS | |
| 99 | Memory impairment | FAERS: 4 | US FAERS | |
| 100 | Neck Pain | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 101 | Nerve injury | FAERS: 4 | US FAERS | |
| 102 | Nervousness | FAERS: 4 | US FAERS | |
| 103 | Pallor | FAERS: 4 | US FAERS | |
| 104 | Pelvic Pain | FAERS: 4 Canada Vigilance: 2 | 4263090 | CTD Canada Vigilance US FAERS |
| 105 | Pneumonia | FAERS: 4 | US FAERS | |
| 106 | Poor quality drug administered | FAERS: 4 | US FAERS | |
| 107 | Presyncope | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 108 | Product dose omission | FAERS: 4 | US FAERS | |
| 109 | Pulmonary Infarction | FAERS: 4 | US FAERS | |
| 110 | Swelling | FAERS: 4 | US FAERS | |
| 111 | White blood cell count decreased | FAERS: 4 | US FAERS | |
| 112 | Activities of daily living impaired | FAERS: 3 | US FAERS | |
| 113 | Angina Pectoris | FAERS: 3 | US FAERS | |
| 114 | Autoimmune thyroiditis | FAERS: 3 | US FAERS | |
| 115 | Blood alkaline phosphatase increased | FAERS: 3 | US FAERS | |
| 116 | Cellulitis | FAERS: 3 | US FAERS | |
| 117 | Chromaturia | FAERS: 3 | US FAERS | |
| 118 | Cytolytic hepatitis | FAERS: 3 | US FAERS | |
| 119 | Deafness | FAERS: 3 | US FAERS | |
| 120 | Drug prescribing error | FAERS: 3 | US FAERS | |
| 121 | Drug withdrawal syndrome | FAERS: 3 | US FAERS | |
| 122 | Dysarthria | FAERS: 3 | US FAERS | |
| 123 | Dysuria | FAERS: 3 | 6524863 | CTD US FAERS |
| 124 | Ecchymosis | FAERS: 3 | US FAERS | |
| 125 | Emotional distress | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 126 | Endometriosis | FAERS: 3 | US FAERS | |
| 127 | Gamma-Glutamyltransferase Increased | FAERS: 3 | US FAERS | |
| 128 | Hepatic Vein Thrombosis | FAERS: 3 | US FAERS | |
| 129 | Hydrocephalus | FAERS: 3 | US FAERS | |
| 130 | Inappropriate schedule of product administration | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 131 | Infection | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 132 | Lip swelling | FAERS: 3 | US FAERS | |
| 133 | Middle insomnia | FAERS: 3 | US FAERS | |
| 134 | Migraine with Aura | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 135 | Muscle Cramp | FAERS: 3 | 2289388 | CTD US FAERS |
| 136 | Musculoskeletal stiffness | FAERS: 3 | US FAERS | |
| 137 | Neutropenia | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 138 | Ocular icterus | FAERS: 3 | US FAERS | |
| 139 | Optic Neuritis | FAERS: 3 | US FAERS | |
| 140 | Palpitations | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 141 | Peripheral swelling | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 142 | Portal Vein Thrombosis | FAERS: 3 | US FAERS | |
| 143 | Product label issue | FAERS: 3 | US FAERS | |
| 144 | Product physical issue | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 145 | Product storage error | FAERS: 3 | US FAERS | |
| 146 | Stevens-Johnson Syndrome | FAERS: 3 | US FAERS | |
| 147 | Stress | FAERS: 3 | US FAERS | |
| 148 | Tachycardia | FAERS: 3 | US FAERS | |
| 149 | Thrombocytopenia | FAERS: 3 | US FAERS | |
| 150 | Tinnitus | FAERS: 3 | US FAERS | |
| 151 | Venous thrombosis limb | FAERS: 3 | US FAERS | |
| 152 | Vertigo | FAERS: 3 | 12057783 | CTD US FAERS |
| 153 | Accidental drug intake by child | FAERS: 2 | US FAERS | |
| 154 | Acute Coronary Syndrome | FAERS: 2 | US FAERS | |
| 155 | Adverse event | FAERS: 2 | US FAERS | |
| 156 | Aphasia | FAERS: 2 | US FAERS | |
| 157 | Apparent death | FAERS: 2 | US FAERS | |
| 158 | Atelectasis | FAERS: 2 | US FAERS | |
| 159 | Atrophic vulvovaginitis | FAERS: 2 | US FAERS | |
| 160 | Bedridden | FAERS: 2 | US FAERS | |
| 161 | Bladder pain | FAERS: 2 | US FAERS | |
| 162 | Blindness | FAERS: 2 | US FAERS | |
| 163 | Blood cholinesterase increased | FAERS: 2 | US FAERS | |
| 164 | Blood immunoglobulin E increased | FAERS: 2 | US FAERS | |
| 165 | Blood lactate dehydrogenase increased | FAERS: 2 | US FAERS | |
| 166 | Blood potassium decreased | FAERS: 2 | US FAERS | |
| 167 | Blood pressure fluctuation | FAERS: 2 | US FAERS | |
| 168 | Blood sodium decreased | FAERS: 2 | US FAERS | |
| 169 | Bone pain | FAERS: 2 | US FAERS | |
| 170 | Burning sensation | FAERS: 2 | US FAERS | |
| 171 | Cardiac Flutter | FAERS: 2 | US FAERS | |
| 172 | Catatonia | FAERS: 2 | US FAERS | |
| 173 | Chills | FAERS: 2 | US FAERS | |
| 174 | Chorioamnionitis | FAERS: 2 | US FAERS | |
| 175 | Drug exposure via breast milk | FAERS: 2 | US FAERS | |
| 176 | Dyslalia | FAERS: 2 | US FAERS | |
| 177 | Dyspareunia | FAERS: 2 | US FAERS | |
| 178 | Dyspepsia | FAERS: 2 | US FAERS | |
| 179 | Endometrial disorder | FAERS: 2 | US FAERS | |
| 180 | Extra dose administered | FAERS: 2 | US FAERS | |
| 181 | Eye pain | FAERS: 2 | US FAERS | |
| 182 | Flushing | FAERS: 2 | US FAERS | |
| 183 | Focal Nodular Hyperplasia | FAERS: 2 | US FAERS | |
| 184 | Food aversion | FAERS: 2 | US FAERS | |
| 185 | Hemiparesis | FAERS: 2 | US FAERS | |
| 186 | Hypoxia | FAERS: 2 | US FAERS | |
| 187 | Impaired driving ability | FAERS: 2 | US FAERS | |
| 188 | Impaired work ability | FAERS: 2 | US FAERS | |
| 189 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 190 | Inflammation | FAERS: 2 | US FAERS | |
| 191 | Joint swelling | FAERS: 2 | US FAERS | |
| 192 | Lethargy | FAERS: 2 | US FAERS | |
| 193 | Lupus-like syndrome | FAERS: 2 | US FAERS | |
| 194 | Multiple Pregnancy | FAERS: 2 | US FAERS | |
| 195 | Myasthenia Gravis | FAERS: 2 | US FAERS | |
| 196 | Nasopharyngitis | FAERS: 2 | US FAERS | |
| 197 | Night sweats | FAERS: 2 | US FAERS | |
| 198 | Overdose | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 199 | Paranoia | FAERS: 2 | US FAERS | |
| 200 | Peliosis Hepatis | FAERS: 2 | US FAERS | |
| 201 | Pericardial effusion | FAERS: 2 | US FAERS | |
| 202 | Personality Change | FAERS: 2 | US FAERS | |
| 203 | Pleuritic pain | FAERS: 2 | US FAERS | |
| 204 | Proteinuria | FAERS: 2 | US FAERS | |
| 205 | Pulmonary artery thrombosis | FAERS: 2 | US FAERS | |
| 206 | Screaming | FAERS: 2 | US FAERS | |
| 207 | Sepsis | FAERS: 2 | US FAERS | |
| 208 | Shoulder Dystocia | FAERS: 2 | US FAERS | |
| 209 | Therapeutic response unexpected | FAERS: 2 | US FAERS | |
| 210 | Tooth Erosion | FAERS: 2 | US FAERS | |
| 211 | Transaminases increased | FAERS: 2 | US FAERS | |
| 212 | Urine human chorionic gonadotropin positive | FAERS: 2 | US FAERS | |
| 213 | Uterine spasm | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 214 | Visual disturbance | FAERS: 2 | US FAERS | |
| 215 | Vulvovaginal burning sensation | FAERS: 2 | US FAERS | |
| 216 | Vulvovaginal dryness | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 217 | Wheezing | FAERS: 2 | US FAERS | |
| 218 | Withdrawal bleeding irregular | FAERS: 2 | US FAERS | |
| 219 | Abdominal symptom | FAERS: 1 | US FAERS | |
| 220 | Abnormal sleep-related event | FAERS: 1 | US FAERS | |
| 221 | Abortion complicated | FAERS: 1 | US FAERS | |
| 222 | Accidental exposure | FAERS: 1 | US FAERS | |
| 223 | Accidental overdose | FAERS: 1 | US FAERS | |
| 224 | Adnexa uteri pain | FAERS: 1 | US FAERS | |
| 225 | Agitation | FAERS: 1 | US FAERS | |
| 226 | Alcohol Intolerance | FAERS: 1 | US FAERS | |
| 227 | Anal Fissure | FAERS: 1 | US FAERS | |
| 228 | Apathy | FAERS: 1 | US FAERS | |
| 229 | Aphagia | FAERS: 1 | US FAERS | |
| 230 | Apparent life threatening event | FAERS: 1 | US FAERS | |
| 231 | Arthropathy | FAERS: 1 | US FAERS | |
| 232 | Autoimmune dermatitis | FAERS: 1 | US FAERS | |
| 233 | Autoimmune hepatitis | FAERS: 1 | US FAERS | |
| 234 | Bipolar Disorder | FAERS: 1 | US FAERS | |
| 235 | Blood albumin decreased | FAERS: 1 | US FAERS | |
| 236 | Blood copper increased | FAERS: 1 | US FAERS | |
| 237 | Blood fibrinogen increased | FAERS: 1 | US FAERS | |
| 238 | Blood glucose abnormal | FAERS: 1 | US FAERS | |
| 239 | Blood iron decreased | FAERS: 1 | US FAERS | |
| 240 | Blood pH increased | FAERS: 1 | US FAERS | |
| 241 | Blood testosterone abnormal | FAERS: 1 | US FAERS | |
| 242 | Blood thyroid stimulating hormone decreased | FAERS: 1 | US FAERS | |
| 243 | Bone swelling | FAERS: 1 | US FAERS | |
| 244 | Bronchitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 245 | Budd-Chiari Syndrome | FAERS: 1 | US FAERS | |
| 246 | Burning Mouth Syndrome | FAERS: 1 | US FAERS | |
| 247 | Candidiasis | FAERS: 1 | US FAERS | |
| 248 | Cardiomegaly | FAERS: 1 | 20632668 | CTD US FAERS |
| 249 | Cervical dysplasia | FAERS: 1 | US FAERS | |
| 250 | Cervix carcinoma | FAERS: 1 | US FAERS | |
| 251 | Chest wall pain | FAERS: 1 | US FAERS | |
| 252 | Choking | FAERS: 1 | US FAERS | |
| 253 | Cholestasis | FAERS: 1 Canada Vigilance: 1 | 11757763 | CTD Canada Vigilance US FAERS |
| 254 | Coagulation factor VIII level increased | FAERS: 1 | US FAERS | |
| 255 | Cold sweat | FAERS: 1 | US FAERS | |
| 256 | Complement factor C1 decreased | FAERS: 1 | US FAERS | |
| 257 | Complications of maternal exposure to therapeutic drugs | FAERS: 1 | US FAERS | |
| 258 | Congenital intestinal malformation | FAERS: 1 | US FAERS | |
| 259 | Contact lens intolerance | FAERS: 1 | US FAERS | |
| 260 | Coronary angioplasty | FAERS: 1 | US FAERS | |
| 261 | Culture urine positive | FAERS: 1 | US FAERS | |
| 262 | Cyanosis | FAERS: 1 | US FAERS | |
| 263 | Cyst | FAERS: 1 | US FAERS | |
| 264 | Dark circles under eyes | FAERS: 1 | US FAERS | |
| 265 | Dental caries | FAERS: 1 | US FAERS | |
| 266 | Depressed Level of Consciousness | FAERS: 1 | US FAERS | |
| 267 | Dermatitis | FAERS: 1 | 4272507 | CTD US FAERS |
| 268 | Discomfort | FAERS: 1 | US FAERS | |
| 269 | Disseminated Intravascular Coagulation | FAERS: 1 | US FAERS | |
| 270 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 271 | Drug effective for unapproved indication | FAERS: 1 | US FAERS | |
| 272 | Drug screen positive | FAERS: 1 | US FAERS | |
| 273 | Dysphemia | FAERS: 1 | US FAERS | |
| 274 | Economic problem | FAERS: 1 | US FAERS | |
| 275 | Electrocardiogram abnormal | FAERS: 1 | US FAERS | |
| 276 | Embolic pneumonia | FAERS: 1 | US FAERS | |
| 277 | Embolic stroke | FAERS: 1 | US FAERS | |
| 278 | Endometrial hypertrophy | FAERS: 1 | US FAERS | |
| 279 | Epistaxis | FAERS: 1 | US FAERS | |
| 280 | Eructation | FAERS: 1 | US FAERS | |
| 281 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 282 | Erythema | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 283 | Extremity necrosis | FAERS: 1 | US FAERS | |
| 284 | Factor V Leiden mutation | FAERS: 1 | US FAERS | |
| 285 | Failure to Thrive | FAERS: 1 | US FAERS | |
| 286 | Feeling Cold | FAERS: 1 | US FAERS | |
| 287 | Feeling jittery | FAERS: 1 | US FAERS | |
| 288 | Fibrin D dimer increased | FAERS: 1 | US FAERS | |
| 289 | Foreign body aspiration | FAERS: 1 | US FAERS | |
| 290 | Formication | FAERS: 1 | US FAERS | |
| 291 | Frustration | FAERS: 1 | US FAERS | |
| 292 | Gastrointestinal hypomotility | FAERS: 1 | US FAERS | |
| 293 | Gastrointestinal infection | FAERS: 1 | US FAERS | |
| 294 | Gene mutation identification test positive | FAERS: 1 | US FAERS | |
| 295 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 296 | Gestational Diabetes | FAERS: 1 | US FAERS | |
| 297 | Hemiparaesthesia | FAERS: 1 | US FAERS | |
| 298 | Hepatitis C antibody positive | FAERS: 1 | US FAERS | |
| 299 | Hepatomegaly | FAERS: 1 | US FAERS | |
| 300 | Hepatotoxicity | FAERS: 1 | US FAERS | |
| 301 | Hyperthyroidism | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 302 | Hypoaesthesia facial | FAERS: 1 | US FAERS | |
| 303 | Hypophagia | FAERS: 1 | US FAERS | |
| 304 | Hypospadias | FAERS: 1 | US FAERS | |
| 305 | Hypotension | FAERS: 1 | US FAERS | |
| 306 | Illogical thinking | FAERS: 1 | US FAERS | |
| 307 | Immature respiratory system | FAERS: 1 | US FAERS | |
| 308 | Impaired self-care | FAERS: 1 | US FAERS | |
| 309 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 310 | Infarction | FAERS: 1 | US FAERS | |
| 311 | Influenza | FAERS: 1 | US FAERS | |
| 312 | Initial insomnia | FAERS: 1 | US FAERS | |
| 313 | Intellectual Disability | FAERS: 1 | US FAERS | |
| 314 | Intentional dose omission | FAERS: 1 | US FAERS | |
| 315 | Intentional misuse | FAERS: 1 | US FAERS | |
| 316 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 317 | Intentional product use issue | FAERS: 1 | US FAERS | |
| 318 | Intestinal infarction | FAERS: 1 | US FAERS | |
| 319 | Joint stiffness | FAERS: 1 | US FAERS | |
| 320 | Limb asymmetry | FAERS: 1 | US FAERS | |
| 321 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 322 | Lymphocyte count increased | FAERS: 1 | US FAERS | |
| 323 | Maternal exposure during delivery | FAERS: 1 | US FAERS | |
| 324 | Meningitis | FAERS: 1 | US FAERS | |
| 325 | Mental impairment | FAERS: 1 | US FAERS | |
| 326 | Mesenteric artery stenosis | FAERS: 1 | US FAERS | |
| 327 | Multiple Sclerosis | FAERS: 1 | US FAERS | |
| 328 | Muscle tightness | FAERS: 1 | US FAERS | |
| 329 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 330 | Musculoskeletal chest pain | FAERS: 1 | US FAERS | |
| 331 | Myalgia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 332 | Myocarditis | FAERS: 1 | US FAERS | |
| 333 | Myositis | FAERS: 1 | US FAERS | |
| 334 | Neonatal cardiac failure | FAERS: 1 | US FAERS | |
| 335 | Neonatal disorder | FAERS: 1 | US FAERS | |
| 336 | Neuralgia | FAERS: 1 | US FAERS | |
| 337 | Neutrophil percentage increased | FAERS: 1 | US FAERS | |
| 338 | Nickel sensitivity | FAERS: 1 | US FAERS | |
| 339 | Oculomucocutaneous syndrome | FAERS: 1 | US FAERS | |
| 340 | Oropharyngeal swelling | FAERS: 1 | US FAERS | |
| 341 | Ovarian germ cell teratoma benign | FAERS: 1 | US FAERS | |
| 342 | Pain of skin | FAERS: 1 | US FAERS | |
| 343 | Pancreatic carcinoma | FAERS: 1 | US FAERS | |
| 344 | Pancreatic duct obstruction | FAERS: 1 | US FAERS | |
| 345 | Pancreatitis | FAERS: 1 | US FAERS | |
| 346 | Panic Disorder | FAERS: 1 | 1592843 | CTD US FAERS |
| 347 | Pelvic venous thrombosis | FAERS: 1 | US FAERS | |
| 348 | Performance status decreased | FAERS: 1 | US FAERS | |
| 349 | Pericarditis | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 350 | Peripheral artery occlusion | FAERS: 1 | US FAERS | |
| 351 | Peripheral occlusive disease | FAERS: 1 | US FAERS | |
| 352 | Phlebitis deep | FAERS: 1 | US FAERS | |
| 353 | Photophobia | FAERS: 1 | US FAERS | |
| 354 | Pleurisy | FAERS: 1 | US FAERS | |
| 355 | Polyuria | FAERS: 1 | US FAERS | |
| 356 | Post procedural complication | FAERS: 1 | US FAERS | |
| 357 | Post procedural pain | FAERS: 1 | US FAERS | |
| 358 | Post-Traumatic Stress Disorder | FAERS: 1 | US FAERS | |
| 359 | Postmenopause | FAERS: 1 | US FAERS | |
| 360 | Pre-Eclampsia | FAERS: 1 | US FAERS | |
| 361 | Pre-existing condition improved | FAERS: 1 | US FAERS | |
| 362 | Pregnancy on contraceptive | FAERS: 1 | US FAERS | |
| 363 | Pregnancy test positive | FAERS: 1 | US FAERS | |
| 364 | Pregnancy with contraceptive device | FAERS: 1 | US FAERS | |
| 365 | Premature Menopause | FAERS: 1 | US FAERS | |
| 366 | Product blister packaging issue | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 367 | Product container issue | FAERS: 1 | US FAERS | |
| 368 | Product measured potency issue | FAERS: 1 | US FAERS | |
| 369 | Product substitution error | FAERS: 1 | US FAERS | |
| 370 | Product taste abnormal | FAERS: 1 | US FAERS | |
| 371 | Protein C decreased | FAERS: 1 | US FAERS | |
| 372 | Protein S decreased | FAERS: 1 | US FAERS | |
| 373 | Protein urine present | FAERS: 1 | US FAERS | |
| 374 | Psoriasis | FAERS: 1 | US FAERS | |
| 375 | Pulmonary Hypertension | FAERS: 1 | US FAERS | |
| 376 | Quadriplegia | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 377 | Quality of life decreased | FAERS: 1 | US FAERS | |
| 378 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 379 | Restlessness | FAERS: 1 | US FAERS | |
| 380 | Retinal Detachment | FAERS: 1 | US FAERS | |
| 381 | Retinal Vein Occlusion | FAERS: 1 | US FAERS | |
| 382 | Retinal exudates | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 383 | Rheumatoid Arthritis | FAERS: 1 | US FAERS | |
| 384 | Ruptured ectopic pregnancy | FAERS: 1 | US FAERS | |
| 385 | Schizophrenia | FAERS: 1 | US FAERS | |
| 386 | Serology positive | FAERS: 1 | US FAERS | |
| 387 | Sinusitis | FAERS: 1 | US FAERS | |
| 388 | Skeletal injury | FAERS: 1 | US FAERS | |
| 389 | Skin irritation | FAERS: 1 | US FAERS | |
| 390 | Skin test positive | FAERS: 1 | US FAERS | |
| 391 | Sluggishness | FAERS: 1 | US FAERS | |
| 392 | Splenic vein thrombosis | FAERS: 1 | US FAERS | |
| 393 | Splenomegaly | FAERS: 1 | US FAERS | |
| 394 | Stillbirth | FAERS: 1 | US FAERS | |
| 395 | Suicide attempt | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 396 | Sunburn | FAERS: 1 | US FAERS | |
| 397 | Suppressed lactation | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 398 | Tachyphrenia | FAERS: 1 | US FAERS | |
| 399 | Tension | FAERS: 1 | US FAERS | |
| 400 | Therapeutic response changed | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 401 | Tonsillitis | FAERS: 1 | US FAERS | |
| 402 | Toothache | FAERS: 1 | US FAERS | |
| 403 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 404 | Ulcer | FAERS: 1 | US FAERS | |
| 405 | Unequal Limb Length | FAERS: 1 | US FAERS | |
| 406 | Unwanted pregnancy | FAERS: 1 | US FAERS | |
| 407 | Uterine Cancer | FAERS: 1 | US FAERS | |
| 408 | Uterine Perforation | FAERS: 1 | US FAERS | |
| 409 | Uterine Rupture | FAERS: 1 | US FAERS | |
| 410 | Vaginal lesion | FAERS: 1 | US FAERS | |
| 411 | Vasculitis | FAERS: 1 | 3451235 | CTD US FAERS |
| 412 | Venous Thrombosis | FAERS: 1 | 8374097 | CTD US FAERS |
| 413 | Ventricular Fibrillation | FAERS: 1 | US FAERS | |
| 414 | Ventricular hypertrophy | FAERS: 1 | US FAERS | |
| 415 | Vertebral Artery Dissection | FAERS: 1 | US FAERS | |
| 416 | Victim of homicide | FAERS: 1 | US FAERS | |
| 417 | Violence-related symptom | FAERS: 1 | US FAERS | |
| 418 | Vulvitis | FAERS: 1 | US FAERS | |
| 419 | Vulvovaginal mycotic infection | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 420 | Vulvovaginal pruritus | FAERS: 1 | US FAERS | |
| 421 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 422 | fibroma | FAERS: 1 | US FAERS | |
| 423 | furuncle | FAERS: 1 | US FAERS | |
| 424 | muscle injury | FAERS: 1 | US FAERS | |
| 425 | nervous system disorder | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 426 | Acne Vulgaris | 4263090 | CTD | |
| 427 | Acute kidney injury | Canada Vigilance: 1 | 2080604 | CTD Canada Vigilance |
| 428 | Adenocarcinoma | 193073 | CTD | |
| 429 | Amenorrhea | CTD | ||
| 430 | Anemia, Hemolytic | 2080604 | CTD | |
| 431 | Atherosclerosis | 11996209 | CTD | |
| 432 | Blepharospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 433 | Butterfly rash | Canada Vigilance: 1 | Canada Vigilance | |
| 434 | Chemical and Drug Induced Liver Injury | 11757763 | CTD | |
| 435 | Chloasma | Canada Vigilance: 1 | Canada Vigilance | |
| 436 | Colitis | Canada Vigilance: 1 | Canada Vigilance | |
| 437 | Decidual cast | Canada Vigilance: 1 | Canada Vigilance | |
| 438 | Diarrhea | 4701037 | CTD | |
| 439 | Dysgeusia | Canada Vigilance: 2 | Canada Vigilance | |
| 440 | Dysmenorrhea | 4263090 12057783 | CTD | |
| 441 | Endometrial Neoplasms | 193073 | CTD | |
| 442 | Erythema Nodosum | Canada Vigilance: 1 | Canada Vigilance | |
| 443 | Feeding and Eating Disorders | 17203115 | CTD | |
| 444 | Gastrointestinal Diseases | 4272507 12057783 | CTD | |
| 445 | Gluten sensitivity | Canada Vigilance: 1 | Canada Vigilance | |
| 446 | Head discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 447 | Hemolytic-Uremic Syndrome | 2080604 | CTD | |
| 448 | Hunger | Canada Vigilance: 1 | Canada Vigilance | |
| 449 | Lower respiratory tract infection | Canada Vigilance: 1 | Canada Vigilance | |
| 450 | Melanosis | 20185226 | CTD | |
| 451 | Mesenteric Vascular Occlusion | 4701037 6524863 | CTD | |
| 452 | Migraine Disorders | 2094059 4263090 | CTD | |
| 453 | Oral candidiasis | Canada Vigilance: 1 | Canada Vigilance | |
| 454 | Parkinsonian Disorders | 1567736 | CTD | |
| 455 | Pharyngeal swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 456 | Polymyositis | Canada Vigilance: 1 | Canada Vigilance | |
| 457 | Product complaint | Canada Vigilance: 1 | Canada Vigilance | |
| 458 | Product packaging quantity issue | Canada Vigilance: 1 | Canada Vigilance | |
| 459 | Recalled product administered | Canada Vigilance: 4 | Canada Vigilance | |
| 460 | Therapeutic product effect decreased | Canada Vigilance: 2 | Canada Vigilance | |
| 461 | Thromboembolism | 4263090 | CTD | |
| 462 | Ultrasound Doppler abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 463 | Venous Thromboembolism | 10357966 | CTD | |
| 464 | Weight Gain | 1183625 | CTD | |
| 465 | jaundice | Canada Vigilance: 1 | Canada Vigilance |
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