MetaADEDB 2.0 @ LMMD
Heat Stroke
(UMLS:C0018843)
Definition:
A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.
UMLS ID:
C0018843
MeSH ID:
D018883
Classification:
Name:
Wounds and Injuries
MeSH Tree Number(s):
C26.522.500
Synonym(s)
1.
Heat Stroke
2.
HEAT APOPLEXY
3.
HEAT STROKE
4.
Heat apoplexy
5.
Heat hyperpyrexia
6.
Heat stroke
7.
Heat stroke, NOS
8.
Overheating
9.
THERMOPLEGIA
10.
Thermoplegia
11.
apoplexy; heat
12.
heat hyperpyrexia
13.
heat stroke
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1TopiramateFAERS: 28US FAERS
2AripiprazoleFAERS: 10SIDER
US FAERS
3rofecoxibFAERS: 10OFFSIDES
US FAERS
4ClozapineFAERS: 8
Canada Vigilance: 3		Canada Vigilance
US FAERS
5Dimethyl FumarateFAERS: 8
Canada Vigilance: 2		Canada Vigilance
US FAERS
6OmeprazoleFAERS: 7US FAERS
7ParoxetineFAERS: 7US FAERS
8TeriparatideFAERS: 7US FAERS
9Glatiramer AcetateFAERS: 6US FAERS
10Imatinib MesylateFAERS: 5US FAERS
11Rosuvastatin CalciumFAERS: 5US FAERS
12Solifenacin SuccinateFAERS: 5OFFSIDES
US FAERS
13ThyroxineFAERS: 5US FAERS
14AlendronateFAERS: 4US FAERS
15GalantamineFAERS: 4US FAERS
16PregabalinFAERS: 4US FAERS
17Quetiapine FumarateFAERS: 4US FAERS
18RamiprilFAERS: 4US FAERS
19Sildenafil CitrateFAERS: 4US FAERS
20Adzenys XR-ODTFAERS: 3US FAERS
21BosentanFAERS: 3US FAERS
22Fingolimod HydrochlorideFAERS: 3US FAERS
23IsotretinoinFAERS: 3US FAERS
24MorphineFAERS: 3US FAERS
25OlanzapineFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
26PhenytoinFAERS: 3US FAERS
27SertralineFAERS: 3US FAERS
28SunitinibFAERS: 3US FAERS
29ValsartanFAERS: 3US FAERS
30ambrisentanFAERS: 3US FAERS
31teriflunomideFAERS: 3US FAERS
32BisoprololFAERS: 2US FAERS
33CarbamazepineFAERS: 2US FAERS
34CelecoxibFAERS: 2US FAERS
35ClopidogrelFAERS: 2US FAERS
36ClopidogrelFAERS: 2US FAERS
37DasatinibFAERS: 2US FAERS
38DonepezilFAERS: 2US FAERS
39Erlotinib HydrochlorideFAERS: 2US FAERS
40EsomeprazoleFAERS: 2US FAERS
41LCZ 696FAERS: 2US FAERS
42Lisdexamfetamine DimesylateFAERS: 2US FAERS
43LithiumFAERS: 2US FAERS
44MethadoneFAERS: 2US FAERS
45VareniclineFAERS: 2US FAERS
46Venlafaxine HydrochlorideFAERS: 2US FAERS
47ZonisamideFAERS: 2SIDER
US FAERS
48trospium chlorideFAERS: 2OFFSIDES
US FAERS
494-AminopyridineFAERS: 1US FAERS
50Aspirin-oxycodone hydrochloride-oxycodone terephthalate combinationFAERS: 1US FAERS
51AspirinFAERS: 1US FAERS
52Atomoxetine HydrochlorideFAERS: 1US FAERS
53BaclofenFAERS: 1US FAERS
54BuprenorphineFAERS: 1US FAERS
55CanagliflozinFAERS: 1US FAERS
56CitalopramFAERS: 1US FAERS
57Duloxetine HydrochlorideFAERS: 1US FAERS
58Estrogens, Conjugated (USP)FAERS: 1OFFSIDES
US FAERS
59Ezetimibe, Simvastatin Drug CombinationFAERS: 1US FAERS
60FentanylFAERS: 1US FAERS
61FinasterideFAERS: 1US FAERS
62FluphenazineFAERS: 1US FAERS
63FluticasoneFAERS: 1US FAERS
64Furadantin monohydrateFAERS: 1US FAERS
65IbuprofenFAERS: 1US FAERS
66Insulin GlargineFAERS: 1US FAERS
67KetamineFAERS: 1US FAERS
68LeflunomideFAERS: 1US FAERS
69LenalidomideFAERS: 1US FAERS
70LosartanFAERS: 1US FAERS
71MDV 3100FAERS: 1US FAERS
72MethotrexateFAERS: 1US FAERS
73MethylphenidateFAERS: 1US FAERS
74MethylphenidateFAERS: 1US FAERS
75ModafinilFAERS: 1US FAERS
76Naphcon AFAERS: 1US FAERS
77Nexium 24hrFAERS: 1US FAERS
78NuvaRingFAERS: 1US FAERS
79Ortho EvraFAERS: 1US FAERS
80PseudoephedrineFAERS: 1US FAERS
81RanolazineFAERS: 1US FAERS
82RisperidoneFAERS: 1SIDER
US FAERS
83RivastigmineFAERS: 1US FAERS
84RosiglitazoneFAERS: 1US FAERS
85SelegilineFAERS: 1US FAERS
86SimvastatinFAERS: 1US FAERS
87TapentadolFAERS: 1US FAERS
88TestosteroneFAERS: 1US FAERS
89Tiotropium BromideFAERS: 1US FAERS
90TramadolFAERS: 1US FAERS
91Valproic AcidFAERS: 1US FAERS
92Valproic AcidFAERS: 1US FAERS
93apixabanFAERS: 1US FAERS
94carbidopa, levodopa drug combinationFAERS: 1US FAERS
95dofetilideFAERS: 1US FAERS
96entecavirFAERS: 1US FAERS
97linaclotideFAERS: 1US FAERS
98oxybutyninFAERS: 1SIDER
US FAERS
99rasagilineFAERS: 1US FAERS
100tofacitinibFAERS: 1US FAERS
101valbenazineFAERS: 1US FAERS
102ziprasidoneFAERS: 1SIDER
US FAERS
103AmisulprideOFFSIDES
104BeclomethasoneOFFSIDES
105Benztropine18025545CTD
OFFSIDES
SIDER
106Clopenthixol18025545CTD
107ClopenthixolOFFSIDES
108Cocaine12190212CTD
109Creatine12182766CTD
110Creatinine16878031CTD
111DantroleneOFFSIDES
112Diphenhydramine12190212CTD
113EtodolacOFFSIDES
114GalantamineOFFSIDES
115Glycerol16878031CTD
116HaloperidolSIDER
117Ketanserin16205318CTD
118LiraglutideCanada Vigilance: 2Canada Vigilance
119LoperamideOFFSIDES
120MaravirocSIDER
121MefloquineOFFSIDES
122MethadoneCanada Vigilance: 1Canada Vigilance
123MethocarbamolOFFSIDES
124NaltrexoneSIDER
125OrlistatOFFSIDES
126OxymorphoneOFFSIDES
127PantoprazoleSIDER
128PropanthelineSIDER
129Quetiapine Fumarate18025545CTD
130RibavirinOFFSIDES
131ScopolamineSIDER
132SelegilineSIDER
133Serotonin16878031CTD
134SulfamethoxazoleOFFSIDES
135SunitinibOFFSIDES
136TrihexyphenidylOFFSIDES
137UbiquinoneOFFSIDES
138abacavir, lamivudine drug combinationOFFSIDES
139carbidopa, levodopa drug combination16878031CTD
140cevimelineSIDER
141dipropylacetamideOFFSIDES
142fosamprenavirOFFSIDES
143ipsapirone16205318CTD
144magnolol12859431CTD
145pimecrolimusOFFSIDES
146tizanidineOFFSIDES
147zolmitriptanOFFSIDES
148zopicloneSIDER
149zotepineOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Heat Exhaustion42.9%
2Frostbite25%
3Athletic Injuries23.1%
4Hand Injuries23.1%
5Soft Tissue Injuries23.1%
6Sprain23.1%
7Sprains and Strains23.1%
8Tendon Injuries23.1%
9Laceration23.1%
10Wounds, Penetrating23.1%
11Rupture23.1%
12Crush syndrome19%
13Femoral Fractures19%
14Tibial Fractures19%
15Hip Fractures17.2%
16Chilblains16.3%
17Spinal Fractures16.3%
18Trauma, Nervous System15.8%
19Bites and Stings15%
20Extravasation of Diagnostic and Therapeutic Materials15%
21Vascular System Injuries15%
22Tympanic Membrane Perforation15%
23Tooth Injuries15%
24Asphyxia14.6%
25Esophageal Perforation14.6%
26Shock, Traumatic14.6%
27Self Mutilation14.5%
28Human Bite14.3%
29Contusions14.3%
30Decompression Sickness14.3%
31Finger Injuries14.3%
32Flail Chest14.3%
33Fractures, Closed14.3%
34Pathological fracture14.3%
35Heart Injuries14.3%
36Knee Injuries14.3%
37Foot Injuries14.3%
38Decapitation14.3%
39Ankle Fracture14.3%
40Avulsion fracture14.3%
41Compression fracture14.3%
42Osteoporotic Fractures14.3%
43Hip Dislocation14%
44Shoulder Dislocation14%
45Splenic Rupture14%
46Hip Dysplasia14%
47Iliotibial Band Syndrome13.6%
48Spinal Cord Injuries10.9%
49Drowning10.7%
50Eye Burns10.5%
51Pseudarthrosis10.3%
52Smoke Inhalation Injury10.3%
53Splenosis10.1%
54Craniocerebral Trauma9.5%
55Tendinitis9.5%
56Lung Injury9.5%
57Tendinopathy9.5%
58Foreign-Body Reaction9.3%
59Insect Bites and Stings9.3%
60Paralysis, Obstetric9.3%
61Sunburn9.3%
62Tooth Avulsion9.3%
63Conus Medullaris Syndrome9.3%
64Near Drowning9.2%
65Osteoradionecrosis9.2%
66Radiation injury8.3%
67Brain Concussion7.2%
68Neoplasms, Radiation-Induced7.2%
69Peripheral Nerve Injuries7%
70Medial Tibial Stress Syndrome7%
71Brain Contusion6.9%
72Uterine Rupture6.8%
73Central Cord Syndrome6.8%
74Facial Injuries6.8%
75Granuloma, Foreign-Body6.8%
76Enthesopathy6.8%
77Uterine Perforation6.7%
78Cardiotoxicity5.6%
79Leukemia, Radiation-Induced5.5%
80Radiation Pneumonitis5.4%
81Radiation Fibrosis5.4%
82Aortic Rupture5.4%
83Brain Injuries5.1%
84Coma, Post-Head Injury5%
85Carpal Tunnel Syndrome5%
86Abnormalities, Radiation-Induced4.5%
87Radiation Injuries, Experimental4.4%
88Eye Injuries4.4%
89Brain Injuries, Diffuse4.1%
90Traumatic Brain Injury4.1%
91Cubital Tunnel Syndrome4.1%
92Brain Hemorrhage, Traumatic4.1%
93Diffuse Axonal Injury3.7%
94Pneumocephalus3.4%
95Olfactory Nerve Injuries3.3%
96Cerebrospinal Fluid Otorrhea3.3%
97Cerebrospinal Fluid Rhinorrhea3.3%
98Vertebral Artery Dissection3.3%
99Epilepsy, Post-Traumatic3.3%
100Corneal Scar3.1%
101Carotid Artery Injuries2.8%
102Corneal Perforation2.8%
103Facial Nerve Injuries2.8%
104Hematoma, Subdural2.3%
105Hematoma, Epidural, Cranial2.3%
106Hematoma, Subdural, Intracranial2.1%
107Hematoma, Subdural, Chronic2.1%
108Hematoma, Subdural, Acute2.1%
109Subarachnoid Hemorrhage, Traumatic2%
110Carotid Artery, Internal, Dissection2%
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