MetaADEDB 2.0 @ LMMD
Pathological fracture
(UMLS:C0016663)
Definition:
Fractures occurring as a result of disease of a bone or from some undiscoverable cause, and not due to trauma. (Dorland, 27th ed)
UMLS ID:
C0016663
MeSH ID:
D005598
Classification:
Name:
Wounds and Injuries
MeSH Tree Number(s):
C26.404.374
Synonym(s)
1.
Pathological fracture
2.
FRACTURE PATHOLOGICAL
3.
Fracture;pathological
4.
Fractures, Spontaneous
5.
PATHOLOGIC FRACTURE
6.
PATHOLOGIC FRACTURE, NOS
7.
PATHOLOGICAL FRACTURE
8.
Pathologic Fracture
9.
Pathologic fracture
10.
Pathologic fracture, unspecified site
11.
Personal history of pathologic fracture
12.
Spontaneous fracture
13.
fracture pathological
14.
fracture; pathological
15.
fracture; spontaneous
16.
pathologic fracture
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1AlendronateFAERS: 149
Canada Vigilance: 13		Canada Vigilance
US FAERS
2Zoledronic AcidFAERS: 117
Canada Vigilance: 2		Canada Vigilance
US FAERS
3LenalidomideFAERS: 72
Canada Vigilance: 1		Canada Vigilance
US FAERS
4TeriparatideFAERS: 59
Canada Vigilance: 3		Canada Vigilance
US FAERS
5AlendronateFAERS: 43US FAERS
6Risedronic AcidFAERS: 32
Canada Vigilance: 4		Canada Vigilance
US FAERS
7ThalidomideFAERS: 25US FAERS
8Ibandronic AcidFAERS: 18US FAERS
9SunitinibFAERS: 17US FAERS
10PamidronateFAERS: 16US FAERS
11Ibandronic AcidFAERS: 9US FAERS
12pomalidomideFAERS: 8US FAERS
13Imatinib MesylateFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
14LetrozoleFAERS: 7US FAERS
15palbociclibFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
16OndansetronFAERS: 6US FAERS
17TenofovirFAERS: 6US FAERS
18TestosteroneFAERS: 6US FAERS
19adefovir dipivoxilFAERS: 6US FAERS
20EnalaprilFAERS: 5US FAERS
21EverolimusFAERS: 5US FAERS
22PioglitazoneFAERS: 5US FAERS
23SorafenibFAERS: 5US FAERS
24rofecoxibFAERS: 5US FAERS
25AxitinibFAERS: 4US FAERS
26BortezomibFAERS: 4US FAERS
27Cabozantinib S-malateFAERS: 4US FAERS
28MethotrexateFAERS: 4US FAERS
29OctreotideFAERS: 4US FAERS
30Valproic AcidFAERS: 4US FAERS
31carfilzomibFAERS: 4US FAERS
32exemestaneFAERS: 4US FAERS
33CanagliflozinFAERS: 3US FAERS
34Erlotinib HydrochlorideFAERS: 3US FAERS
35MDV 3100FAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
36MeloxicamFAERS: 3US FAERS
37Raloxifene HydrochlorideFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
38RosiglitazoneFAERS: 3
Canada Vigilance: 2		Canada Vigilance
US FAERS
39TenofovirFAERS: 3US FAERS
40Venlafaxine HydrochlorideFAERS: 3US FAERS
41paricalcitolFAERS: 3US FAERS
42strontium chlorideFAERS: 3US FAERS
434-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 2US FAERS
44Abiraterone AcetateFAERS: 2US FAERS
45Atacand hctFAERS: 2US FAERS
46BosentanFAERS: 2US FAERS
47CapecitabineFAERS: 2US FAERS
48CarbamazepineFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
49DoxorubicinFAERS: 2US FAERS
50Duloxetine HydrochlorideFAERS: 2US FAERS
51Erlotinib HydrochlorideFAERS: 2US FAERS
52Fluticasone/salmeterolFAERS: 2US FAERS
53Fosamax plus DFAERS: 2US FAERS
54OmeprazoleFAERS: 2US FAERS
55PCI 32765FAERS: 2US FAERS
56PrednisoloneFAERS: 2US FAERS
57RivastigmineFAERS: 2
Canada Vigilance: 30		Canada Vigilance
US FAERS
58Sitagliptin PhosphateFAERS: 2US FAERS
59SunitinibFAERS: 2US FAERS
60ValacyclovirFAERS: 2US FAERS
61lenvatinibFAERS: 2US FAERS
62liposomal doxorubicinFAERS: 2US FAERS
63macitentanFAERS: 2US FAERS
64pazopanibFAERS: 2US FAERS
65ponatinibFAERS: 2US FAERS
66samarium Sm-153 lexidronamFAERS: 2US FAERS
67tofacitinibFAERS: 2US FAERS
68(3S,4R)-3-(1,3-Benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;methanesulfonateFAERS: 1US FAERS
69AP26113FAERS: 1US FAERS
70AfatinibFAERS: 1US FAERS
71AmiodaroneFAERS: 1US FAERS
72AripiprazoleFAERS: 1US FAERS
73CiprofloxacinFAERS: 1US FAERS
74ClopidogrelFAERS: 1US FAERS
75CyclosporineFAERS: 1US FAERS
76DelavirdineFAERS: 1US FAERS
77DexamethasoneFAERS: 1US FAERS
78DocetaxelFAERS: 1US FAERS
79DronedaroneFAERS: 1US FAERS
80Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
81EstradiolFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
82Etidronic AcidFAERS: 1US FAERS
83Fingolimod HydrochlorideFAERS: 1US FAERS
84FluoxetineFAERS: 1US FAERS
85FulvestrantFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
86GefitinibFAERS: 1US FAERS
87Glatiramer AcetateFAERS: 1US FAERS
88GoserelinFAERS: 1US FAERS
89HydrochlorothiazideFAERS: 1US FAERS
90INCB018424FAERS: 1US FAERS
91IloprostFAERS: 1US FAERS
92IsotretinoinFAERS: 1US FAERS
93LeuprolideFAERS: 1US FAERS
94Medroxyprogesterone AcetateFAERS: 1US FAERS
95MorphineFAERS: 1US FAERS
96Naloxegol oxalateFAERS: 1US FAERS
97OmeprazoleFAERS: 1US FAERS
98OxcarbazepineFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
99PaclitaxelFAERS: 1US FAERS
100ParoxetineFAERS: 1US FAERS
101PemetrexedFAERS: 1US FAERS
102PregabalinFAERS: 1US FAERS
103Risedronic AcidFAERS: 1US FAERS
104RivaroxabanFAERS: 1US FAERS
105Ruxolitinib phosphateFAERS: 1US FAERS
106TacrolimusFAERS: 1US FAERS
107Tiotropium BromideFAERS: 1US FAERS
108TopiramateFAERS: 1US FAERS
109Triamcinolone AcetonideFAERS: 1US FAERS
110Valproic AcidFAERS: 1US FAERS
111ValsartanFAERS: 1US FAERS
112acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamideFAERS: 1US FAERS
113eliglustatFAERS: 1US FAERS
114eribulinFAERS: 1US FAERS
115eribulinFAERS: 1US FAERS
116ledipasvir, sofosbuvir drug combinationFAERS: 1US FAERS
117miglustatFAERS: 1US FAERS
118osimertinibFAERS: 1US FAERS
119pazopanibFAERS: 1US FAERS
120pirfenidoneFAERS: 1US FAERS
121salmon calcitoninFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
122temsirolimusFAERS: 1US FAERS
123valdecoxibFAERS: 1US FAERS
124ziprasidoneFAERS: 1US FAERS
125CitalopramCanada Vigilance: 1Canada Vigilance
126ClozapineCanada Vigilance: 10Canada Vigilance
127DiltiazemCanada Vigilance: 1Canada Vigilance
128DonepezilCanada Vigilance: 2Canada Vigilance
129GoserelinCanada Vigilance: 1Canada Vigilance
130LansoprazoleCanada Vigilance: 1Canada Vigilance
131LopinavirCanada Vigilance: 1Canada Vigilance
132LorazepamCanada Vigilance: 1Canada Vigilance
133MethylphenidateCanada Vigilance: 1Canada Vigilance
134MisoprostolCanada Vigilance: 1Canada Vigilance
135PhenytoinCanada Vigilance: 1Canada Vigilance
136PramipexoleCanada Vigilance: 1Canada Vigilance
137PrednisoneCanada Vigilance: 2Canada Vigilance
138RisperidoneCanada Vigilance: 1Canada Vigilance
139Sildenafil CitrateCanada Vigilance: 1Canada Vigilance
140alfuzosinCanada Vigilance: 1Canada Vigilance
141pimecrolimusCanada Vigilance: 1Canada Vigilance
142trandolaprilCanada Vigilance: 1Canada Vigilance
Similar ADE(s)
NameSemantic Similarity
1Fractures, Closed42.9%
2Ankle Fracture42.9%
3Avulsion fracture42.9%
4Compression fracture42.9%
5Osteoporotic Fractures42.9%
6Femoral Fractures38.1%
7Tibial Fractures38.1%
8Spinal Fractures34.9%
9Pseudarthrosis31%
10Hip Fractures27.6%
11Frostbite25%
12Athletic Injuries23.1%
13Hand Injuries23.1%
14Soft Tissue Injuries23.1%
15Sprain23.1%
16Sprains and Strains23.1%
17Tendon Injuries23.1%
18Laceration23.1%
19Wounds, Penetrating23.1%
20Heat Cramps23.1%
21Rupture23.1%
22Crush syndrome19%
23Chilblains16.3%
24Trauma, Nervous System15.8%
25Bites and Stings15%
26Extravasation of Diagnostic and Therapeutic Materials15%
27Vascular System Injuries15%
28Tympanic Membrane Perforation15%
29Tooth Injuries15%
30Asphyxia14.6%
31Esophageal Perforation14.6%
32Shock, Traumatic14.6%
33Self Mutilation14.5%
34Human Bite14.3%
35Contusions14.3%
36Decompression Sickness14.3%
37Finger Injuries14.3%
38Flail Chest14.3%
39Heart Injuries14.3%
40Heat Exhaustion14.3%
41Heat Stroke14.3%
42Knee Injuries14.3%
43Foot Injuries14.3%
44Decapitation14.3%
45Hip Dislocation14%
46Shoulder Dislocation14%
47Splenic Rupture14%
48Hip Dysplasia14%
49Iliotibial Band Syndrome13.6%
50Spinal Cord Injuries10.9%
51Drowning10.7%
52Eye Burns10.5%
53Smoke Inhalation Injury10.3%
54Splenosis10.1%
55Craniocerebral Trauma9.5%
56Tendinitis9.5%
57Lung Injury9.5%
58Tendinopathy9.5%
59Foreign-Body Reaction9.3%
60Insect Bites and Stings9.3%
61Paralysis, Obstetric9.3%
62Sunburn9.3%
63Tooth Avulsion9.3%
64Conus Medullaris Syndrome9.3%
65Near Drowning9.2%
66Osteoradionecrosis9.2%
67Radiation injury8.3%
68Brain Concussion7.2%
69Neoplasms, Radiation-Induced7.2%
70Peripheral Nerve Injuries7%
71Medial Tibial Stress Syndrome7%
72Brain Contusion6.9%
73Uterine Rupture6.8%
74Central Cord Syndrome6.8%
75Facial Injuries6.8%
76Granuloma, Foreign-Body6.8%
77Enthesopathy6.8%
78Uterine Perforation6.7%
79Cardiotoxicity5.6%
80Leukemia, Radiation-Induced5.5%
81Radiation Pneumonitis5.4%
82Radiation Fibrosis5.4%
83Aortic Rupture5.4%
84Brain Injuries5.1%
85Coma, Post-Head Injury5%
86Carpal Tunnel Syndrome5%
87Abnormalities, Radiation-Induced4.5%
88Radiation Injuries, Experimental4.4%
89Eye Injuries4.4%
90Brain Injuries, Diffuse4.1%
91Traumatic Brain Injury4.1%
92Cubital Tunnel Syndrome4.1%
93Brain Hemorrhage, Traumatic4.1%
94Diffuse Axonal Injury3.7%
95Pneumocephalus3.4%
96Olfactory Nerve Injuries3.3%
97Cerebrospinal Fluid Otorrhea3.3%
98Cerebrospinal Fluid Rhinorrhea3.3%
99Vertebral Artery Dissection3.3%
100Epilepsy, Post-Traumatic3.3%
101Corneal Scar3.1%
102Carotid Artery Injuries2.8%
103Corneal Perforation2.8%
104Facial Nerve Injuries2.8%
105Hematoma, Subdural2.3%
106Hematoma, Epidural, Cranial2.3%
107Hematoma, Subdural, Intracranial2.1%
108Hematoma, Subdural, Chronic2.1%
109Hematoma, Subdural, Acute2.1%
110Subarachnoid Hemorrhage, Traumatic2%
111Carotid Artery, Internal, Dissection2%
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.