MetaADEDB 2.0 @ LMMD
Gemfibrozil
(HEMJJKBWTPKOJG-UHFFFAOYSA-N)
Structure
SMILES
Cc1ccc(c(c1)OCCCC(C(=O)O)(C)C)C
Type(s)
Approved
ATC code(s)
C10AB04
Molecular Formula:
C15H22O3
Molecular Weight:
250.333
Log P:
3.5732
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
46.53
CAS Number(s):
25812-30-0
Synonym(s)
1.
Gemfibrozil
2.
Apo-Gemfibrozil
3.
Ausgem
4.
Bolutol
5.
CI-719
6.
Chem mart Gemfibrozil
7.
DBL Gemfibrozil
8.
Decrelip
9.
Gemfi 1A Pharma
10.
Gemfibrosil
11.
Gemfibrozilo Bayvit
12.
Gemfibrozilo Bexal
13.
Gemfibrozilo Ur
14.
Gemhexal
15.
Gen-Gemfibrozil
16.
GenRX Gemfibrozil
17.
Healthsense Gemfibrozil
18.
Jezil
19.
Lipazil
20.
Lipox Gemfi
21.
Lipur
22.
Litarek
23.
Lopid
24.
Lopid R
25.
Novo-Gemfibrozil
26.
Nu-Gemfibrozil
27.
PMS-Gemfibrozil
28.
Pilder
29.
SBPA Gemfibrozil
30.
Terry White Chemists Gemfibrozil
31.
Trialmin
32.
Apo Gemfibrozil
33.
ApoGemfibrozil
34.
Bayvit, Gemfibrozilo
35.
CI 719
36.
CI719
37.
Gemfibrozil, GenRX
38.
Gemfibrozil, Healthsense
39.
Gemfibrozil, SBPA
40.
Gen Gemfibrozil
41.
GenGemfibrozil
42.
Novo Gemfibrozil
43.
Nu Gemfibrozil
44.
NuGemfibrozil
45.
PMS Gemfibrozil
External Link(s)
MeSHD015248
PubChem Compound3463
BindingDB50110590
ChEBI5296
CHEMBLCHEMBL457
DrugBankDB01241
DrugCentral1285
IUPHAR/BPS Guide to PHARMACOLOGY3439
KEGGcpd:C07020
dr:D00334
Therapeutic Target DatabaseD05VIX
ZINC1530641
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1MyalgiaFAERS: 36SIDER
US FAERS
2NauseaFAERS: 30OFFSIDES
SIDER
US FAERS
3VomitingFAERS: 23SIDER
US FAERS
4RhabdomyolysisFAERS: 21

View details

2297197
2355431
8252847
8893176
9160078
10190540
10959522
11173785
11371708
11447919
11573847
11795020
12380704
14742756
16235714
16400396
18157972
18956824
 		CTD
OFFSIDES
SIDER
US FAERS
5DizzinessFAERS: 17OFFSIDES
SIDER
US FAERS
6FatigueFAERS: 17OFFSIDES
SIDER
US FAERS
7PruritusFAERS: 16
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
8Abdominal PainFAERS: 15OFFSIDES
SIDER
US FAERS
9AstheniaFAERS: 14OFFSIDES
SIDER
US FAERS
10Drug ineffectiveFAERS: 14US FAERS
11MalaiseFAERS: 14US FAERS
12PainFAERS: 11SIDER
US FAERS
13Abdominal discomfortFAERS: 10OFFSIDES
US FAERS
14ArthralgiaFAERS: 107670796CTD
SIDER
US FAERS
15Chest PainFAERS: 10OFFSIDES
SIDER
US FAERS
16Cerebrovascular accidentFAERS: 9US FAERS
17HeadacheFAERS: 9
Canada Vigilance: 2		2329850
2903970		CTD
SIDER
Canada Vigilance
US FAERS
18Weight decreasedFAERS: 7SIDER
US FAERS
19Blood triglycerides increasedFAERS: 6OFFSIDES
US FAERS
20HypersensitivityFAERS: 6US FAERS
21PancreatitisFAERS: 6OFFSIDES
SIDER
US FAERS
22UrticariaFAERS: 6SIDER
US FAERS
23AbasiaFAERS: 5US FAERS
24Blood cholesterol increasedFAERS: 5US FAERS
25Blood creatine phosphokinase increasedFAERS: 5SIDER
US FAERS
26Blood glucose increasedFAERS: 5US FAERS
27Feeling ColdFAERS: 5US FAERS
28SomnolenceFAERS: 5SIDER
US FAERS
29AnxietyFAERS: 4OFFSIDES
US FAERS
30Back PainFAERS: 47670796CTD
US FAERS
31Blood creatinine increasedFAERS: 4OFFSIDES
US FAERS
32Burning sensationFAERS: 4US FAERS
33CholelithiasisFAERS: 424385052CTD
SIDER
US FAERS
34Drug dispensing errorFAERS: 4US FAERS
35DyspepsiaFAERS: 4
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
36Product substitution issueFAERS: 4US FAERS
37Product taste abnormalFAERS: 4US FAERS
38AlopeciaFAERS: 3SIDER
US FAERS
39ChillsFAERS: 3US FAERS
40ConstipationFAERS: 3SIDER
US FAERS
41Diabetes MellitusFAERS: 3US FAERS
42Feeling abnormalFAERS: 3SIDER
US FAERS
43HepatitisFAERS: 39844285CTD
US FAERS
44Musculoskeletal PainFAERS: 3SIDER
US FAERS
45NervousnessFAERS: 3SIDER
US FAERS
46Oropharyngeal painFAERS: 3OFFSIDES
US FAERS
47PneumoniaFAERS: 3US FAERS
48SwellingFAERS: 3US FAERS
49SyncopeFAERS: 3SIDER
US FAERS
50TinnitusFAERS: 3US FAERS
51AmyloidosisFAERS: 2US FAERS
52Amyotrophic Lateral SclerosisFAERS: 2US FAERS
53ArthropathyFAERS: 2US FAERS
54BlindnessFAERS: 2US FAERS
55Cardiac dysfunctionFAERS: 2US FAERS
56CardiomegalyFAERS: 2US FAERS
57ChromaturiaFAERS: 2US FAERS
58DeafnessFAERS: 2US FAERS
59Drug administration errorFAERS: 2US FAERS
60Drug prescribing errorFAERS: 2OFFSIDES
US FAERS
61DysgeusiaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
62DysphemiaFAERS: 2US FAERS
63Echocardiogram abnormalFAERS: 2OFFSIDES
US FAERS
64Erectile dysfunctionFAERS: 2
Canada Vigilance: 1

View details

1393117
1978015
8364294
9567433
 		CTD
SIDER
Canada Vigilance
US FAERS
65General physical health deteriorationFAERS: 2US FAERS
66HyperacusisFAERS: 2US FAERS
67HypokinesiaFAERS: 2US FAERS
68Lack of spontaneous speechFAERS: 2US FAERS
69Medication ErrorFAERS: 2US FAERS
70Mental impairmentFAERS: 2US FAERS
71Muscle FatigueFAERS: 2US FAERS
72Myocardial InfarctionFAERS: 2US FAERS
73MyopathyFAERS: 2SIDER
US FAERS
74MyositisFAERS: 2

View details

1615846
8000060
8417294
14605512
19934390
 		CTD
US FAERS
75PalpitationsFAERS: 2US FAERS
76Pharmaceutical product complaintFAERS: 2OFFSIDES
US FAERS
77PhotophobiaFAERS: 2US FAERS
78PresyncopeFAERS: 2US FAERS
79Product quality issueFAERS: 2OFFSIDES
US FAERS
80Product use issueFAERS: 2US FAERS
81RestlessnessFAERS: 2US FAERS
82StomatitisFAERS: 2US FAERS
83Suicide attemptFAERS: 2US FAERS
84Tardive DyskinesiaFAERS: 2US FAERS
85Therapeutic response unexpectedFAERS: 2US FAERS
86Urinary tract infectionFAERS: 2SIDER
US FAERS
87VertigoFAERS: 2SIDER
US FAERS
88Visual ImpairmentFAERS: 2US FAERS
89jaundiceFAERS: 2SIDER
US FAERS
90AbscessFAERS: 1US FAERS
91Accidental overdoseFAERS: 1US FAERS
92Activities of daily living impairedFAERS: 1US FAERS
93Adenoid Cystic CarcinomaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
94Adverse eventFAERS: 1US FAERS
95AgeusiaFAERS: 1OFFSIDES
US FAERS
96AgitationFAERS: 1US FAERS
97AmblyopiaFAERS: 1US FAERS
98AngerFAERS: 1US FAERS
99Angina PectorisFAERS: 1US FAERS
100AnosmiaFAERS: 1US FAERS
101ArthritisFAERS: 18422571CTD
US FAERS
102AscitesFAERS: 1US FAERS
103Aspartate Aminotransferase IncreasedFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
104AtaxiaFAERS: 1US FAERS
105Atrial FibrillationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
106Bacterial test positiveFAERS: 1US FAERS
107BedriddenFAERS: 1US FAERS
108Benign Prostatic HyperplasiaFAERS: 1US FAERS
109Blood alkaline phosphatase increasedFAERS: 1SIDER
US FAERS
110Blood creatine phosphokinase MB increasedFAERS: 1OFFSIDES
US FAERS
111Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
112Blood urea increasedFAERS: 1OFFSIDES
US FAERS
113Bowel movement irregularityFAERS: 1US FAERS
114Breakthrough PainFAERS: 1US FAERS
115CheilitisFAERS: 1US FAERS
116ChokingFAERS: 1US FAERS
117CholestasisFAERS: 1US FAERS
118Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
119Cluster HeadacheFAERS: 1US FAERS
120CystitisFAERS: 1US FAERS
121DehydrationFAERS: 1US FAERS
122DiplopiaFAERS: 1US FAERS
123DisorientationFAERS: 1US FAERS
124Drug DependenceFAERS: 1US FAERS
125Drug dose omissionFAERS: 1OFFSIDES
US FAERS
126Drug exposure during pregnancyFAERS: 1US FAERS
127Drug toxicityFAERS: 1US FAERS
128DysphoniaFAERS: 1US FAERS
129Erythema MultiformeFAERS: 1US FAERS
130Eye irritationFAERS: 1US FAERS
131Eye painFAERS: 1US FAERS
132Fixed eruptionFAERS: 1US FAERS
133FlatulenceFAERS: 1OFFSIDES
SIDER
US FAERS
134FlushingFAERS: 1US FAERS
135Gastric ulcerFAERS: 1OFFSIDES
US FAERS
136GastritisFAERS: 1US FAERS
137Gastrointestinal PainFAERS: 1SIDER
US FAERS
138Head discomfortFAERS: 1US FAERS
139Heat illnessFAERS: 1US FAERS
140HungerFAERS: 1US FAERS
141HypophagiaFAERS: 1US FAERS
142HypotensionFAERS: 1US FAERS
143Impaired driving abilityFAERS: 1US FAERS
144Inappropriate schedule of drug administrationFAERS: 1OFFSIDES
US FAERS
145Incorrect dose administeredFAERS: 1US FAERS
146InfluenzaFAERS: 1US FAERS
147Intercepted drug dispensing errorFAERS: 1US FAERS
148Joint Range of Motion DecreasedFAERS: 1US FAERS
149Labile blood pressureFAERS: 1US FAERS
150LethargyFAERS: 1OFFSIDES
US FAERS
151LeukocytosisFAERS: 1US FAERS
152Live BirthFAERS: 1US FAERS
153LymphadenopathyFAERS: 1US FAERS
154Maternal exposure during pregnancyFAERS: 1US FAERS
155Memory impairmentFAERS: 1US FAERS
156Mental status changesFAERS: 1OFFSIDES
US FAERS
157Middle insomniaFAERS: 1US FAERS
158Mood swingsFAERS: 1US FAERS
159Muscle CrampFAERS: 1US FAERS
160Peripheral swellingFAERS: 1US FAERS
161PoisoningFAERS: 1US FAERS
162Poor quality drug administeredFAERS: 1US FAERS
163Portal tract inflammationFAERS: 1US FAERS
164Product comminglingFAERS: 1US FAERS
165Product container seal issueFAERS: 1US FAERS
166Product counterfeitFAERS: 1US FAERS
167Product dispensing errorFAERS: 1US FAERS
168Product identification number issueFAERS: 1US FAERS
169Product packaging issueFAERS: 1US FAERS
170Reaction to drug excipientsFAERS: 1US FAERS
171Rectal polypFAERS: 1US FAERS
172Renal painFAERS: 1US FAERS
173SciaticaFAERS: 1US FAERS
174Similar reaction on previous exposure to drugFAERS: 1US FAERS
175Soft tissue massFAERS: 1US FAERS
176TachycardiaFAERS: 1US FAERS
177Therapy cessationFAERS: 1US FAERS
178Urinary RetentionFAERS: 1US FAERS
179Urine output increasedFAERS: 1US FAERS
180muscle injuryFAERS: 1US FAERS
181treatment failureFAERS: 1US FAERS
182Abdominal tendernessOFFSIDES
183Abnormal visionOFFSIDES
184Acid refluxOFFSIDES
185AcidosisOFFSIDES
186Acute bronchitisOFFSIDES
187Acute kidney injury

View details

2297197
2355431
8893176
11173785
11371708
11447919
11795020
14742756
 		CTD
188Acute prerenal failureOFFSIDES
189Acute respiratory failureOFFSIDES
190Alanine Aminotransferase IncreasedCanada Vigilance: 1Canada Vigilance
191AmnesiaOFFSIDES
192Anal FissureOFFSIDES
193Anaphylactic shockSIDER
194Angioedema of larynxSIDER
195AngioedemaOFFSIDES
SIDER
196Antinuclear antibody increasedSIDER
197Anuria11795020CTD
198Aortic AneurysmOFFSIDES
199AphoniaOFFSIDES
200ApoptosisOFFSIDES
201AppendicitisSIDER
202ArteriosclerosisOFFSIDES
203Atherosclerosis9690910CTD
204Atrial thrombosisOFFSIDES
205Bipolar DisorderOFFSIDES
206Blood GlucoseOFFSIDES
207Blood amylase increasedOFFSIDES
208Blood and lymphatic system disordersSIDER
209Blood chloride decreasedOFFSIDES
210Blood cholesterolOFFSIDES
211Blood glucose abnormalOFFSIDES
212Blood glucose decreasedOFFSIDES
213Body TemperatureOFFSIDES
214Bone density decreasedOFFSIDES
215Bone marrow depressionSIDER
216Brain ConcussionOFFSIDES
217BronchitisOFFSIDES
218BruxismOFFSIDES
219BursitisOFFSIDES
220Cardiovascular Diseases10680050
12163127		CTD
221CataractSIDER
222Catheter related complicationOFFSIDES
223CellulitisOFFSIDES
224Central line infectionOFFSIDES
225Chemical and Drug Induced Liver Injury24385052CTD
226Choking sensationOFFSIDES
227CholecystitisSIDER
228Chronic Fatigue SyndromeOFFSIDES
229Chronic Obstructive Airway DiseaseOFFSIDES
230ColitisSIDER
231Common ColdSIDER
232Compartment syndromes8000060
8417294		CTD
233Complement factor C1 decreasedOFFSIDES
234Concomitant disease progressionOFFSIDES
235ConfabulationOFFSIDES
236Congenital tricuspid valve incompetenceOFFSIDES
237ConjunctivitisCanada Vigilance: 1Canada Vigilance
238Coronary Artery Disease11123853
16511610		CTD
239Coronary Stenosis15657157CTD
240Creatine Phosphokinase IncreasedSIDER
241CystCanada Vigilance: 1Canada Vigilance
242Dental abscessOFFSIDES
243Depressed moodOFFSIDES
244DermatitisSIDER
245DextrocardiaCanada Vigilance: 1Canada Vigilance
246DiabetesOFFSIDES
247Diabetes mellitus inadequate controlOFFSIDES
248Diabetic NephropathyOFFSIDES
249Diabetic RetinopathyOFFSIDES
250DiarrheaOFFSIDES
251Disturbance in sexual arousalSIDER
252Drug withdrawal headacheOFFSIDES
253Dyslipidemias

View details

8941582
9515185
16259526
16707586
 		CTD
254EczemaSIDER
255Ejection Fraction DecreasedOFFSIDES
256Electromechanical dissociationOFFSIDES
257Emotional distressOFFSIDES
258EncephaloceleCanada Vigilance: 1Canada Vigilance
259EndocarditisOFFSIDES
260Endometrial HyperplasiaOFFSIDES
261EosinophiliaSIDER
262Epigastric painSIDER
263EpistaxisOFFSIDES
264EscharOFFSIDES
265Escherichia sepsisOFFSIDES
266ExcoriationOFFSIDES
267Extremity necrosisOFFSIDES
268Eye inflammationOFFSIDES
269Facial NeuralgiaOFFSIDES
270Fatty LiverOFFSIDES
271Fear of fallingOFFSIDES
272Flank PainOFFSIDES
273Fluid overloadOFFSIDES
274FormicationOFFSIDES
275Full blood count decreasedOFFSIDES
276GastroenteritisOFFSIDES
277GlomerulonephritisOFFSIDES
278GoutSIDER
279Hepatomegaly

View details

7497472
9007043
20953357
28108177
 		CTD
280Hypercholesterolemia

View details

1521554
2067654
7670796
9678787
 		CTD
281Hyperlipoproteinemia Type IV2903970CTD
282HyperparathyroidismOFFSIDES
283Hypertriglyceridemia

View details

7670796
8593127
9006809
9678787
11701466
11794424
15304625
17163263
 		CTD
284Hypertrophic CardiomyopathyOFFSIDES
285Hypoalphalipoproteinemias11701466
15657157		CTD
286HysterectomyOFFSIDES
287Immunosuppressant drug level decreasedOFFSIDES
288Increased upper airway secretionOFFSIDES
289Infected insect biteOFFSIDES
290Infusion site mobility decreasedOFFSIDES
291Insulin-requiring type 2 diabetes mellitusOFFSIDES
292Intervertebral disc disorderOFFSIDES
293Intestinal AtresiaCanada Vigilance: 1Canada Vigilance
294Intestinal ObstructionOFFSIDES
295Intestinal PerforationOFFSIDES
296Intestinal resectionOFFSIDES
297Intraocular pressure testOFFSIDES
298Jaundice, Obstructive24385052CTD
299Kidney FailureOFFSIDES
300Kidney NeoplasmOFFSIDES
301Large intestine perforationOFFSIDES
302LeukopeniaSIDER
303LipaseOFFSIDES
304Liver neoplasms25058030
28108177		CTD
305Lumbar radiculopathyOFFSIDES
306Lung consolidationOFFSIDES
307Lupus-like syndromeSIDER
308Lymphocytic infiltrationOFFSIDES
309MegacolonOFFSIDES
310Metabolic acidosisOFFSIDES
311Mitochondrial Diseases17499714CTD
312Muscle Weakness1521554CTD
313Musculoskeletal chest painOFFSIDES
314Musculoskeletal discomfortOFFSIDES
SIDER
315NasopharyngitisSIDER
316Negative thoughtsOFFSIDES
317Nephrogenic Fibrosing DermopathyOFFSIDES
318NeuritisSIDER
319NocturiaCanada Vigilance: 1Canada Vigilance
320Nodal osteoarthritisOFFSIDES
321NoduleOFFSIDES
322Non-cardiac chest painOFFSIDES
323Occult blood positiveOFFSIDES
324Open woundOFFSIDES
325OsteomyelitisOFFSIDES
326PancytopeniaSIDER
327Panic DisorderOFFSIDES
328PeriodontitisOFFSIDES
329PeritonitisOFFSIDES
330Pharyngolaryngeal PainOFFSIDES
331Polyomavirus-associated nephropathyOFFSIDES
332PolyuriaCanada Vigilance: 1Canada Vigilance
333Portal HypertensionOFFSIDES
334Portal triaditisOFFSIDES
335Postoperative infectionOFFSIDES
336Postoperative wound complicationOFFSIDES
337Pulmonary congestionOFFSIDES
338RalesOFFSIDES
339Raynaud Disease8422571CTD
340Reaction gastrointestinalSIDER
341Rectal fissureOFFSIDES
342Renal Insufficiency

View details

8252847
8941582
10190540
10959522
12380704
 		CTD
343Renal cystOFFSIDES
344Respiratory FailureOFFSIDES
345Retinal DegenerationOFFSIDES
346Retinal Vascular DisorderOFFSIDES
347Rheumatoid NoduleOFFSIDES
348RhinitisSIDER
349ScabOFFSIDES
350Schizoaffective DisorderOFFSIDES
351Septic ShockOFFSIDES
352ShockSIDER
353Sinus bradycardiaOFFSIDES
354Sinus headacheOFFSIDES
355Skin necrosisOFFSIDES
356SmokerOFFSIDES
357StressOFFSIDES
358Synovitis8422571CTD
SIDER
359TensionSIDER
360Therapy regimen changedOFFSIDES
361ThrombocytopeniaSIDER
362Thrombophlebitis8422571CTD
363Tooth ExtractionOFFSIDES
364ToxoplasmosisOFFSIDES
365Troponin increasedOFFSIDES
366UlcerOFFSIDES
367Unevaluable eventOFFSIDES
368Urinary tract infection staphylococcalOFFSIDES
369VasculitisSIDER
370Venous stasisOFFSIDES
371Walking aid userOFFSIDES
372Wound infection pseudomonasOFFSIDES
373Wound infection staphylococcalOFFSIDES
374Wrong technique in drug usage processOFFSIDES
375nervous system disorderSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120329

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.