Cefixime
(OKBVVJOGVLARMR-QSWIMTSFSA-N)
Structure
- SMILES
- Nc1nc(cs1)/C(=N/OCC(=O)O)/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)C=C
- Type(s)
- Approved; Investigational
- ATC code(s)
- J01DD08
- Molecular Formula:
- C16H15N5O7S2
- Molecular Weight:
- 453.450
- Log P:
- 0.3652
- Hydrogen Bond Acceptor:
- 14
- Hydrogen Bond Donor:
- 4
- TPSA:
- 238.05
- CAS Number(s):
- 79350-37-1
Synonym(s)
1.
Cefixime
2.
Cefixime Anhydrous
3.
Cefixime Trihydrate
4.
FK 027
5.
FK-027
6.
FR-17027
7.
Suprax
8.
FK027
9.
FR 17027
10.
FR17027
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Erythema | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 2 | Clostridium difficile colitis | FAERS: 4 Canada Vigilance: 3 | Canada Vigilance OFFSIDES US FAERS | |
| 3 | Hypersensitivity | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 4 | Urticaria | FAERS: 4 Canada Vigilance: 3 | 24329898 | CTD SIDER Canada Vigilance US FAERS |
| 5 | Arthralgia | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 6 | Pruritus | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 7 | Vomiting | FAERS: 3 Canada Vigilance: 8 | 1906097 | CTD SIDER Canada Vigilance US FAERS |
| 8 | Weight decreased | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 9 | Abdominal Pain | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance SIDER US FAERS | |
| 10 | Angioedema | FAERS: 2 | OFFSIDES SIDER US FAERS | |
| 11 | Asthenia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Chest discomfort | FAERS: 2 | US FAERS | |
| 13 | Clostridium colitis | FAERS: 2 | US FAERS | |
| 14 | Joint swelling | FAERS: 2 | US FAERS | |
| 15 | Lip swelling | FAERS: 2 | US FAERS | |
| 16 | Malaise | FAERS: 2 | US FAERS | |
| 17 | Nausea | FAERS: 2 Canada Vigilance: 7 | Canada Vigilance SIDER US FAERS | |
| 18 | Pain | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 19 | Palmar erythema | FAERS: 2 | OFFSIDES US FAERS | |
| 20 | Papule | FAERS: 2 | US FAERS | |
| 21 | Serum Sickness | FAERS: 2 | SIDER US FAERS | |
| 22 | Serum sickness-like reaction | FAERS: 2 | US FAERS | |
| 23 | Swelling | FAERS: 2 | US FAERS | |
| 24 | Abdominal discomfort | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 25 | Anorexia | FAERS: 1 | OFFSIDES US FAERS | |
| 26 | Anxiety | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 27 | Arthritis | FAERS: 1 | US FAERS | |
| 28 | Ascites | FAERS: 1 | US FAERS | |
| 29 | Blindness | FAERS: 1 | US FAERS | |
| 30 | Cataract | FAERS: 1 | US FAERS | |
| 31 | Chest Pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Cholestasis | FAERS: 1 | SIDER US FAERS | |
| 33 | Cold sweat | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 34 | Colitis | FAERS: 1 | SIDER US FAERS | |
| 35 | Corneal Opacity | FAERS: 1 | US FAERS | |
| 36 | Dehydration | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 37 | Demyelination | FAERS: 1 | US FAERS | |
| 38 | Dizziness | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance SIDER US FAERS | |
| 39 | Erythema Multiforme | FAERS: 1 | SIDER US FAERS | |
| 40 | Feeling Cold | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 41 | Fibrin D dimer increased | FAERS: 1 | US FAERS | |
| 42 | Fixed eruption | FAERS: 1 | OFFSIDES US FAERS | |
| 43 | Flatulence | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 44 | Headache | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 45 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 46 | Irritable Bowel Syndrome | FAERS: 1 | US FAERS | |
| 47 | Leukocytosis | FAERS: 1 | US FAERS | |
| 48 | Leukopenia | FAERS: 1 | SIDER US FAERS | |
| 49 | Lymphadenitis | FAERS: 1 | US FAERS | |
| 50 | Medication Error | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 51 | Neutropenia | FAERS: 1 | SIDER US FAERS | |
| 52 | Oculomucocutaneous syndrome | FAERS: 1 | US FAERS | |
| 53 | Oral mucosal erythema | FAERS: 1 | US FAERS | |
| 54 | Pallor | FAERS: 1 | US FAERS | |
| 55 | Pemphigus | FAERS: 1 | US FAERS | |
| 56 | Prurigo | FAERS: 1 | US FAERS | |
| 57 | Rash erythematous | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 58 | Septic Shock | FAERS: 1 | OFFSIDES US FAERS | |
| 59 | Skin lesion | FAERS: 1 | OFFSIDES US FAERS | |
| 60 | Somnolence | FAERS: 1 | US FAERS | |
| 61 | Stevens-Johnson Syndrome | FAERS: 1 | 25811541 | CTD SIDER US FAERS |
| 62 | Stomatitis | FAERS: 1 | US FAERS | |
| 63 | Syncope | FAERS: 1 | US FAERS | |
| 64 | Toxic Epidermal Necrolysis | FAERS: 1 | SIDER US FAERS | |
| 65 | Tremor | FAERS: 1 | US FAERS | |
| 66 | Unevaluable event | FAERS: 1 | US FAERS | |
| 67 | Vascular pain | FAERS: 1 | US FAERS | |
| 68 | Wheezing | FAERS: 1 | US FAERS | |
| 69 | pseudomembranous colitis | FAERS: 1 Canada Vigilance: 9 | Canada Vigilance SIDER US FAERS | |
| 70 | Acantholysis | OFFSIDES | ||
| 71 | Accidental overdose | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 72 | Acid reflux | OFFSIDES | ||
| 73 | Acute otitis media | OFFSIDES | ||
| 74 | Agoraphobia | OFFSIDES | ||
| 75 | Agranulocytosis | SIDER | ||
| 76 | Alanine Aminotransferase Increased | OFFSIDES | ||
| 77 | Anaphylactic shock | SIDER | ||
| 78 | Anaphylactoid Reaction | SIDER | ||
| 79 | Ataxia | OFFSIDES | ||
| 80 | Autoimmune thrombocytopenia | OFFSIDES | ||
| 81 | Biopsy bone marrow abnormal | OFFSIDES | ||
| 82 | Blood albumin increased | OFFSIDES | ||
| 83 | Blood alkaline phosphatase increased | OFFSIDES | ||
| 84 | Blood lactate dehydrogenase increased | SIDER | ||
| 85 | Blood sodium | OFFSIDES | ||
| 86 | Bradycardia | OFFSIDES | ||
| 87 | Bronchitis | 2041146 | CTD | |
| 88 | Congenital tracheomalacia | OFFSIDES | ||
| 89 | Conjunctival abrasion | OFFSIDES | ||
| 90 | Coombs test positive | SIDER | ||
| 91 | Crying | Canada Vigilance: 1 | Canada Vigilance | |
| 92 | Cytolytic hepatitis | OFFSIDES | ||
| 93 | Depressed mood | Canada Vigilance: 1 | Canada Vigilance | |
| 94 | Dermatitis | SIDER | ||
| 95 | Dextrocardia | OFFSIDES | ||
| 96 | Diarrhea | 1906097 2041146 | CTD OFFSIDES | |
| 97 | Disease recurrence | OFFSIDES | ||
| 98 | Dyspepsia | SIDER | ||
| 99 | Eczema | OFFSIDES | ||
| 100 | Enteritis | Canada Vigilance: 1 | Canada Vigilance | |
| 101 | Eosinophilia | SIDER | ||
| 102 | Epistaxis | Canada Vigilance: 1 | Canada Vigilance | |
| 103 | Erythema Nodosum | OFFSIDES | ||
| 104 | Escherichia coli Infections | 15466073 | CTD | |
| 105 | Exanthema | 1906097 | CTD | |
| 106 | Expired product administered | Canada Vigilance: 1 | Canada Vigilance | |
| 107 | Fatigue | Canada Vigilance: 1 | Canada Vigilance | |
| 108 | Fatty Liver | OFFSIDES | ||
| 109 | Gamma-Glutamyltransferase Increased | OFFSIDES | ||
| 110 | Gastroenteritis | OFFSIDES | ||
| 111 | Gastrointestinal Pain | SIDER | ||
| 112 | Gastrointestinal sounds abnormal | OFFSIDES | ||
| 113 | Haemophilus Infections | 1906097 2041146 | CTD | |
| 114 | Hemiplegia | OFFSIDES | ||
| 115 | Hepatic artery thrombosis | OFFSIDES | ||
| 116 | Hepatic necrosis | OFFSIDES | ||
| 117 | Hepatitis B | OFFSIDES | ||
| 118 | Hepatitis | SIDER | ||
| 119 | Hypersomnia | Canada Vigilance: 1 | Canada Vigilance | |
| 120 | Hypophagia | Canada Vigilance: 1 | Canada Vigilance | |
| 121 | Hysterectomy | OFFSIDES | ||
| 122 | Impaired driving ability | OFFSIDES | ||
| 123 | Inappropriate schedule of drug administration | OFFSIDES | ||
| 124 | Incontinence | OFFSIDES | ||
| 125 | Infection | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 126 | Infusion site mobility decreased | OFFSIDES | ||
| 127 | Injection site discomfort | OFFSIDES | ||
| 128 | Injection site erythema | OFFSIDES | ||
| 129 | Intestinal Perforation | Canada Vigilance: 1 | Canada Vigilance | |
| 130 | Lactic dehydrogenase activity increased | SIDER | ||
| 131 | Leukopenia neonatal | OFFSIDES | ||
| 132 | Meningitis | SIDER | ||
| 133 | Musculoskeletal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 134 | Nephrotic Syndrome | 10528699 | CTD | |
| 135 | Otitis Media | 1906097 1957129 | CTD | |
| 136 | PROTHROMBIN TIME | OFFSIDES | ||
| 137 | Pancytopenia | SIDER | ||
| 138 | Peripheral swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 139 | Peritonitis | OFFSIDES | ||
| 140 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 141 | Pharyngitis | 2041146 | CTD | |
| 142 | Pharyngolaryngeal Pain | OFFSIDES | ||
| 143 | Pneumococcal Infections | 1906097 | CTD | |
| 144 | Pneumococcal sepsis | OFFSIDES | ||
| 145 | Pneumonia | 2041146 | CTD | |
| 146 | Post procedural complication | OFFSIDES | ||
| 147 | Presbyopia | OFFSIDES | ||
| 148 | Product quality issue | OFFSIDES | ||
| 149 | Purulence | OFFSIDES | ||
| 150 | Purulent discharge | OFFSIDES | ||
| 151 | Respiratory Tract Infections | 2041146 | CTD | |
| 152 | Salmonella infections | 9759304 | CTD | |
| 153 | Schizoaffective Disorder | OFFSIDES | ||
| 154 | Screaming | Canada Vigilance: 2 | Canada Vigilance | |
| 155 | Sense of oppression | OFFSIDES | ||
| 156 | Shock | SIDER | ||
| 157 | Skin hypertrophy | OFFSIDES | ||
| 158 | Skin necrosis | OFFSIDES | ||
| 159 | Streptococcal Infections | 2041146 | CTD | |
| 160 | Superinfection | SIDER | ||
| 161 | Therapy non-responder | OFFSIDES | ||
| 162 | Thrombocytopenia | SIDER | ||
| 163 | Thrombocytosis | SIDER | ||
| 164 | Tonsillitis | 2041146 | CTD | |
| 165 | Tracheal fistula | OFFSIDES | ||
| 166 | Tympanic Membrane Perforation | OFFSIDES | ||
| 167 | Urinary tract infection | SIDER | ||
| 168 | Vestibular Neuronitis | OFFSIDES | ||
| 169 | Vitamin A Deficiency | OFFSIDES | ||
| 170 | Walking aid user | OFFSIDES | ||
| 171 | furuncle | OFFSIDES | ||
| 172 | jaundice | SIDER |
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