MetaADEDB 2.0 @ LMMD
Chlorpropamide
(RKWGIWYCVPQPMF-UHFFFAOYSA-N)
Structure
SMILES
CCCNC(=O)NS(=O)(=O)c1ccc(cc1)Cl
Type(s)
Approved; Investigational
ATC code(s)
A10BB02
Molecular Formula:
C10H13ClN2O3S
Molecular Weight:
276.740
Log P:
3.6005
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
2
TPSA:
83.65
CAS Number(s):
94-20-2
Synonym(s)
1.
Chlorpropamide
2.
Clorpropamid
3.
Apo-Chlorpropamide
4.
Diabinese
5.
Glucamide
6.
Insogen
7.
Meldian
External Link(s)
MeSHD002747
PubChem Compound2727
BindingDB50344965
ChEBI3650
CHEMBLCHEMBL498
DrugBankDB00672
DrugCentral622
IUPHAR/BPS Guide to PHARMACOLOGY6801
KEGGdr:D00271
Therapeutic Target DatabaseD00BCP
ZINC1530599
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Diabetes mellitus inadequate controlFAERS: 3OFFSIDES
US FAERS
2Drug ineffectiveFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
3Accidental exposure to productFAERS: 2US FAERS
4Cerebrovascular accidentFAERS: 2US FAERS
5DizzinessFAERS: 2OFFSIDES
SIDER
US FAERS
6ErythemaFAERS: 2US FAERS
7FormicationFAERS: 2OFFSIDES
US FAERS
8HeadacheFAERS: 2SIDER
US FAERS
9Medication ErrorFAERS: 2US FAERS
10Toxicity to various agentsFAERS: 2US FAERS
11Urinary tract infectionFAERS: 2US FAERS
12VomitingFAERS: 215251538CTD
SIDER
US FAERS
13AmnesiaFAERS: 1OFFSIDES
US FAERS
14Cerebral InfarctionFAERS: 1US FAERS
15ChokingFAERS: 1US FAERS
16Diabetes MellitusFAERS: 1

View details

879949
1201169
1814884
6047854
7057563
7218172
8928190
 		CTD
US FAERS
17Feeling abnormalFAERS: 1OFFSIDES
US FAERS
18Incorrect dose administeredFAERS: 1US FAERS
19Limb injuryFAERS: 1US FAERS
20Myocardial InfarctionFAERS: 1US FAERS
21NauseaFAERS: 115251538CTD
SIDER
US FAERS
22OsteoporosisFAERS: 1US FAERS
23OverdoseFAERS: 1US FAERS
24Pharmaceutical product complaintFAERS: 1OFFSIDES
US FAERS
25PneumoniaFAERS: 1US FAERS
26Portal HypertensionFAERS: 1US FAERS
27Senile dementiaFAERS: 1OFFSIDES
US FAERS
28UrticariaFAERS: 1
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
29AbasiaOFFSIDES
30Abdominal PainCanada Vigilance: 1Canada Vigilance
OFFSIDES
31Acute myocardial infarctionOFFSIDES
32AgranulocytosisSIDER
33AgraphiaOFFSIDES
34Alcohol IntoleranceSIDER
35Altered bowel functionOFFSIDES
36AmblyopiaCanada Vigilance: 1Canada Vigilance
37Anemia, Hemolytic3766527
5458054		CTD
38Angina Pectoris4694904CTD
39AngiodysplasiaOFFSIDES
40AnorexiaOFFSIDES
SIDER
41Antibiotic ProphylaxisOFFSIDES
42AnxietyCanada Vigilance: 1Canada Vigilance
OFFSIDES
43ArthritisOFFSIDES
44AstheniaCanada Vigilance: 1Canada Vigilance
OFFSIDES
45AsthmaCanada Vigilance: 1Canada Vigilance
46Bile Duct Diseases3265170CTD
47Biopsy breast abnormalOFFSIDES
48Blood GlucoseOFFSIDES
49Blood albumin decreasedOFFSIDES
50Blood cholesterolOFFSIDES
51Blood glucose abnormalOFFSIDES
52Blood glucose decreasedOFFSIDES
53Blood lactate dehydrogenase increasedOFFSIDES
54Blood pressure immeasurableOFFSIDES
55Blood triglycerides increasedOFFSIDES
56Blurred visionOFFSIDES
57Brain Diseases, Metabolic879949CTD
58BronchitisOFFSIDES
59Bulbar palsyOFFSIDES
60CarcinomaOFFSIDES
61Cataract operationOFFSIDES
62CataractOFFSIDES
63CellulitisOFFSIDES
64Chemical and Drug Induced Liver Injury24085192CTD
65ChillsCanada Vigilance: 1Canada Vigilance
66Choking sensationOFFSIDES
67Cholestasis4007403
15251538		CTD
68CirrhosisOFFSIDES
69CyanosisCanada Vigilance: 1Canada Vigilance
70CystOFFSIDES
71DeafnessOFFSIDES
72Demyelinating Diseases8928190CTD
73Dental cariesOFFSIDES
74DermatitisCanada Vigilance: 36218754CTD
Canada Vigilance
75DiabetesOFFSIDES
76Diabetes Insipidus4694904
4848193		CTD
77Diabetic NephropathyOFFSIDES
78Diabetic gastropathyOFFSIDES
79Disease ProgressionOFFSIDES
80Disulfiram like reactionSIDER
81DiverticulitisOFFSIDES
82DiverticulumOFFSIDES
83Drug withdrawal headacheOFFSIDES
84DuodenitisOFFSIDES
85DyspepsiaSIDER
86DysphoniaCanada Vigilance: 1Canada Vigilance
OFFSIDES
87Edema18777112CTD
88Electrocardiogram repolarisation abnormalityOFFSIDES
89Enterocolitis, Pseudomembranous2859803CTD
90EosinophiliaSIDER
91Erosive gastritisOFFSIDES
92Erythema MultiformeOFFSIDES
SIDER
93Esophageal StenosisOFFSIDES
94Exanthema15251538CTD
95Eye painOFFSIDES
96Flushing728707
728708		CTD
97GlobulinuriaOFFSIDES
98Glomerulonephritis6218754CTD
99Glucose Metabolism Disorders16273134CTD
100GoutOFFSIDES
101HepatitisCanada Vigilance: 16218754CTD
Canada Vigilance
102Hepatomegaly28108177CTD
103HungerSIDER
104Hypoglycemia

View details

879949
1201169
2043180
4848193
5560028
7057563
7396601
 		CTD
105Hyponatremia

View details

1421649
1814884
3865878
5029389
6842150
8928190
 		CTD
106HypotensionCanada Vigilance: 1Canada Vigilance
107ImpatienceOFFSIDES
108IncontinenceOFFSIDES
109Infection in an immunocompromised hostOFFSIDES
110Intention tremorOFFSIDES
111Intermittent ClaudicationOFFSIDES
112Intervertebral Disc DegenerationOFFSIDES
113Jaundice, Obstructive2859803
7403921		CTD
114Kidney FailureOFFSIDES
115LazinessOFFSIDES
116LeukopeniaSIDER
117Lichen PlanusOFFSIDES
118Lip swellingCanada Vigilance: 1Canada Vigilance
119Liver diseases10216414CTD
120Lung AbscessOFFSIDES
121Mallory-Weiss SyndromeOFFSIDES
122Metabolic acidosisCanada Vigilance: 1Canada Vigilance
123Multiple MyelomaOFFSIDES
124Muscle WeaknessOFFSIDES
125Musculoskeletal discomfortOFFSIDES
126MyalgiaCanada Vigilance: 1Canada Vigilance
127NephrolithiasisOFFSIDES
128Nephrosis473209CTD
129Nephrotic Syndrome6218754CTD
130Nervous tensionOFFSIDES
131OsteomyelitisOFFSIDES
132OsteopeniaOFFSIDES
133PainOFFSIDES
134PancytopeniaSIDER
135Panic DisorderOFFSIDES
136Poor quality sleepOFFSIDES
137Porphyria Cutanea TardaSIDER
138Porphyria non-acuteSIDER
139Post procedural complicationOFFSIDES
140Postoperative Complications1201169CTD
141Postoperative infectionOFFSIDES
142ProctocolitisSIDER
143PruritusCanada Vigilance: 1Canada Vigilance
SIDER
144Pulmonary toxicityOFFSIDES
145Renal tubular disorderOFFSIDES
146ShockCanada Vigilance: 15560028CTD
Canada Vigilance
147Sinus bradycardiaOFFSIDES
148Soft Tissue InfectionOFFSIDES
149Spinal fusion surgeryOFFSIDES
150Stevens-Johnson SyndromeCanada Vigilance: 1Canada Vigilance
151StuporCanada Vigilance: 1Canada Vigilance
152Suicide attemptCanada Vigilance: 1Canada Vigilance
153Synovial CystOFFSIDES
154TachycardiaCanada Vigilance: 1Canada Vigilance
155Therapeutic procedureOFFSIDES
156ThrombocytopeniaSIDER
157Tooth InfectionOFFSIDES
158Urination Disorders8928190CTD
159Vitamin B 12 DeficiencyOFFSIDES
160Water Intoxication4694904CTD
161jaundiceCanada Vigilance: 47396601
15251538		CTD
Canada Vigilance
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