aristolochic acid I
(BBFQZRXNYIEMAW-UHFFFAOYSA-N)
Structure
- SMILES
- COc1cccc2c1cc([N+](=O)[O-])c1c2c2OCOc2cc1C(=O)O
- Molecular Formula:
- C17H11NO7
- Molecular Weight:
- 341.272
- Log P:
- 3.8599
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 1
- TPSA:
- 110.81
- CAS Number(s):
- 313-67-7; 61117-05-3
Synonym(s)
1.
aristolochic acid I
2.
8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid
3.
Tardolyt
4.
aristolochic acid
5.
aristolochic acid A
6.
aristolochic acid I, sodium salt
7.
sodium aristolochate
External Link(s)
| MeSH | C000228 |
| PubChem Compound | 2236 |
| BindingDB | 50306855 |
| ChEBI | 2825 |
| CHEMBL | CHEMBL93353 |
| KEGG | cpd:C08469 |
| ZINC | 52 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Acute kidney injury | 24530882 26204831 27422293 | CTD | |
| 2 | Balkan Nephropathy | CTD | ||
| 3 | Carcinoma, Transitional Cell | 26204831 | CTD | |
| 4 | Carcinoma | 25209566 | CTD | |
| 5 | Cardiovascular Abnormalities | 22472514 | CTD | |
| 6 | Hemorrhage | 18381687 | CTD | |
| 7 | Inflammation | 22472514 | CTD | |
| 8 | Kidney Diseases | CTD | ||
| 9 | Necrosis | 24530882 | CTD | |
| 10 | Neoplasms | 21642617 | CTD | |
| 11 | Renal Insufficiency | 19643159 22472514 | CTD | |
| 12 | Testicular Diseases | 26656393 31009690 | CTD | |
| 13 | Urologic Neoplasms | 21932800 22071594 22086975 | CTD |
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