Aconitine
(XFSBVAOIAHNAPC-XTHSEXKGSA-N)
Structure
- SMILES
- COC[C@@]12CN(CC)C3[C@]4([C@@H]2[C@@H](OC)[C@@H]3[C@@]2([C@@H]3[C@H]4C[C@@]([C@@H]3OC(=O)c3ccccc3)([C@H]([C@@H]2O)OC)O)OC(=O)C)[C@H](C[C@H]1O)OC
- Molecular Formula:
- C34H47NO11
- Molecular Weight:
- 645.737
- Log P:
- 0.5860
- Hydrogen Bond Acceptor:
- 12
- Hydrogen Bond Donor:
- 3
- TPSA:
- 153.45
- CAS Number(s):
- 302-27-2
Synonym(s)
1.
Aconitine
2.
Acetylbenzoylaconine
3.
Acetylbenzoyl-aconine
4.
Acetylbenzoyl aconine
External Link(s)
| MeSH | D000157 |
| PubChem Compound | 245005 |
| ChEBI | 2430 |
| CHEMBL | CHEMBL1979562 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 2617 |
| KEGG | cpd:C06091 |
| Therapeutic Target Database | D0A1MW |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Atrial Fibrillation | CTD | ||
| 2 | Atrial Flutter | 6628657 | CTD | |
| 3 | Bradycardia | 30639578 | CTD | |
| 4 | Cardiomyopathies | 28193520 | CTD | |
| 5 | Cardiotoxicity | 24840785 | CTD | |
| 6 | Cardiovascular Abnormalities | 30639578 | CTD | |
| 7 | Diarrhea | 28193520 | CTD | |
| 8 | Dyspnea | 28193520 | CTD | |
| 9 | Edema | 28193520 | CTD | |
| 10 | Gait Disorders, Neurologic | 28193520 | CTD | |
| 11 | Hemorrhage | 30639578 | CTD | |
| 12 | Inflammation | 28193520 | CTD | |
| 13 | Lethargy | 28193520 | CTD | |
| 14 | Neoplasm Invasiveness | 18844224 | CTD | |
| 15 | Neurotoxicity Syndromes | 28193520 | CTD | |
| 16 | Pain | 28193520 | CTD | |
| 17 | Pericardial effusion | 30639578 | CTD | |
| 18 | Poisoning | 23562926 24840785 | CTD | |
| 19 | Seizures | 28193520 | CTD | |
| 20 | Sialorrhea | 28193520 | CTD | |
| 21 | Torsades de Pointes | 2463611 | CTD | |
| 22 | Ventricular Dysfunction | 30639578 | CTD | |
| 23 | Ventricular Fibrillation | 11808 1776484 | CTD | |
| 24 | Vomiting | 28193520 | CTD |
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