MetaADEDB 2.0 @ LMMD
Trimethadione
(IRYJRGCIQBGHIV-UHFFFAOYSA-N)
Structure
SMILES
O=C1OC(C(=O)N1C)(C)C
Type(s)
Approved
ATC code(s)
N03AC02
Molecular Formula:
C6H9NO3
Molecular Weight:
143.141
Log P:
0.3115
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
0
TPSA:
46.61
CAS Number(s):
127-48-0
Synonym(s)
1.
Trimethadione
2.
Tridione
3.
Trimetin
4.
Troxidone
External Link(s)
MeSHD014293
PubChem Compound5576
BindingDB50227239
ChEBI9727
CHEMBLCHEMBL695
DrugBankDB00347
DrugCentral2751
IUPHAR/BPS Guide to PHARMACOLOGY7316
KEGGdr:D00392
Therapeutic Target DatabaseD0U4VT
ZINC1530710
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AnorexiaFAERS: 1SIDER
US FAERS
2PancytopeniaFAERS: 1SIDER
US FAERS
3SomnolenceFAERS: 1SIDER
US FAERS
4White blood cell count decreasedFAERS: 1US FAERS
5Abdominal PainSIDER
6Abnormalities, Drug-Induced

View details

50427
413897
550945
4193708
4572938
6195326
 		CTD
7AgranulocytosisSIDER
8AlbuminuriaSIDER
9AlopeciaSIDER
10Anxiety Disorders6129593CTD
11AstheniaSIDER
12Blood pressure fluctuationSIDER
13Calculi7827299CTD
14Cardiovascular Abnormalities50427CTD
15Craniofacial Abnormalities413897CTD
16DermatitisSIDER
17Developmental Disabilities50427
413897		CTD
18DiplopiaSIDER
19DiscomfortSIDER
20DistressSIDER
21DrowsinessSIDER
22Emotional distressSIDER
23EosinophiliaSIDER
24Epilepsies, Partial3922381CTD
25Epilepsy413897
821787		CTD
26EpistaxisSIDER
27Erythema MultiformeSIDER
28Eye Abnormalities50427CTD
29FatigueSIDER
30Feeling abnormalSIDER
31Gastrointestinal PainSIDER
32Growth Disorders413897
6195326		CTD
33HeadacheSIDER
34HepatitisSIDER
35Hepatomegaly28108177CTD
36HepatosplenomegalySIDER
37LeukopeniaSIDER
38Liver Neoplasms, Experimental1444806CTD
39Lupus ErythematosusSIDER
40LymphadenopathySIDER
41LymphomaSIDER
42MalaiseSIDER
43Microcephaly50427CTD
44Motor Skills Disorders6195326CTD
45Myasthenia Gravis4987393CTD
46Myasthenia gravis-like syndromeSIDER
47Myasthenic SyndromeSIDER
48NauseaSIDER
49Nephrosis4961747CTD
SIDER
50Nephrotic Syndrome4631174
6071127		CTD
SIDER
51NeutropeniaSIDER
52Pancreatitis7827299CTD
53Personality ChangeSIDER
54PhotophobiaSIDER
55Precancerous Conditions1444806CTD
56Prenatal Exposure Delayed Effects413897
4080065		CTD
57PruritusSIDER
58Seizures

View details

565846
779804
2905779
3137016
3607518
5451364
10087439
 		CTD
59ThrombocytopeniaSIDER
60VertigoSIDER
61VomitingSIDER
62Weight decreasedSIDER
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