MetaADEDB 2.0 @ LMMD
Desogestrel
(RPLCPCMSCLEKRS-BPIQYHPVSA-N)
Structure
SMILES
CC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@@]2(O)C#C)CCC1=CCCC[C@H]31
Type(s)
Approved
ATC code(s)
G03AA09; G03AB05; G03AC09; G03FB10
Molecular Formula:
C22H30O
Molecular Weight:
310.473
Log P:
4.8697
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
1
TPSA:
20.23
CAS Number(s):
54024-22-5
Synonym(s)
1.
Desogestrel
2.
13-Ethyl-11-methylene-18,19-dinor-17 alpha-pregn-4-en-20-yn-17-ol
3.
Cerazette
4.
Marvelon
5.
Org-2969
6.
13 Ethyl 11 methylene 18,19 dinor 17 alpha pregn 4 en 20 yn 17 ol
7.
Org 2969
8.
Org2969
9.
alpha-pregn-4-en-20-yn-17-ol, 13-Ethyl-11-methylene-18,19-dinor-17
External Link(s)
MeSHD017135
PubChem Compound40973
BindingDB50423510
ChEBI4453
CHEMBLCHEMBL1533
DrugBankDB00304
DrugCentral818
IUPHAR/BPS Guide to PHARMACOLOGY7065
KEGGcpd:C07629
dr:D02367
Therapeutic Target DatabaseD06CGB
ZINC4097416
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Pulmonary EmbolismFAERS: 82978521CTD
US FAERS
2MetrorrhagiaFAERS: 5US FAERS
3No adverse eventFAERS: 5US FAERS
4Drug ineffectiveFAERS: 4US FAERS
5Abdominal PainFAERS: 3SIDER
US FAERS
6Drug dose omissionFAERS: 3US FAERS
7Feeling abnormalFAERS: 3US FAERS
8AnxietyFAERS: 2US FAERS
9Drug administration errorFAERS: 2US FAERS
10HeadacheFAERS: 27750278
9678128
12499030
CTD
SIDER
US FAERS
11Inappropriate schedule of drug administrationFAERS: 2US FAERS
12MenorrhagiaFAERS: 2US FAERS
13NauseaFAERS: 27750278
9678128
CTD
OFFSIDES
SIDER
US FAERS
14Product use issueFAERS: 2US FAERS
15ThrombosisFAERS: 218342649CTD
US FAERS
16Weight decreasedFAERS: 2SIDER
US FAERS
17AbasiaFAERS: 1US FAERS
18Accidental overdoseFAERS: 1US FAERS
19Acute myocardial infarctionFAERS: 1US FAERS
20Adverse eventFAERS: 1US FAERS
21Alanine Aminotransferase IncreasedFAERS: 1OFFSIDES
US FAERS
22AlopeciaFAERS: 1OFFSIDES
SIDER
US FAERS
23AneurysmFAERS: 1US FAERS
24Anoxic EncephalopathyFAERS: 1US FAERS
25Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
26Blood glucose increasedFAERS: 1US FAERS
27Blood magnesium increasedFAERS: 1US FAERS
28Blood potassium increasedFAERS: 1US FAERS
29Blood sodium increasedFAERS: 1US FAERS
30Blood triglycerides increasedFAERS: 1OFFSIDES
US FAERS
31Brain DeathFAERS: 1US FAERS
32BronchitisFAERS: 1OFFSIDES
US FAERS
33Cardiac ArrestFAERS: 1US FAERS
34Carpal Tunnel SyndromeFAERS: 1US FAERS
35ConstipationFAERS: 1US FAERS
36CryingFAERS: 1OFFSIDES
US FAERS
37Deep Vein ThrombosisFAERS: 1US FAERS
38Depression suicidalFAERS: 1US FAERS
39DizzinessFAERS: 1OFFSIDES
US FAERS
40Drug ToleranceFAERS: 1US FAERS
41Drug ineffective for unapproved indicationFAERS: 1US FAERS
42Drug monitoring procedure incorrectly performedFAERS: 1US FAERS
43Drug prescribing errorFAERS: 1US FAERS
44DysgeusiaFAERS: 1OFFSIDES
US FAERS
45EmbolismFAERS: 1US FAERS
46EndometriosisFAERS: 1US FAERS
47Euphoric moodFAERS: 1US FAERS
48Expired product administeredFAERS: 1US FAERS
49Exposure during breast feedingFAERS: 1US FAERS
50Focal Nodular HyperplasiaFAERS: 1OFFSIDES
US FAERS
51General physical health deteriorationFAERS: 1US FAERS
52HypersensitivityFAERS: 1SIDER
US FAERS
53Incorrect drug administration durationFAERS: 1US FAERS
54Incorrect product storageFAERS: 1US FAERS
55Intentional product use issueFAERS: 1US FAERS
56Labile hypertensionFAERS: 1US FAERS
57MalaiseFAERS: 1US FAERS
58Maternal exposure during pregnancyFAERS: 1US FAERS
59Medication ErrorFAERS: 1US FAERS
60Myocardial InfarctionFAERS: 1US FAERS
61NephrolithiasisFAERS: 1US FAERS
62ObstructionFAERS: 1US FAERS
63PainFAERS: 1OFFSIDES
US FAERS
64Pelvic fluid collectionFAERS: 1US FAERS
65Peripheral venous diseaseFAERS: 1US FAERS
66Pharmaceutical product complaintFAERS: 1US FAERS
67Pityriasis Rubra PilarisFAERS: 1US FAERS
68PneumoniaFAERS: 1US FAERS
69Product availability issueFAERS: 1US FAERS
70Product dispensing errorFAERS: 1US FAERS
71PruritusFAERS: 1US FAERS
72Renal lithiasis prophylaxisFAERS: 1US FAERS
73Respiratory arrestFAERS: 1US FAERS
74Right Ventricular HypertrophyFAERS: 1US FAERS
75Splenic vein thrombosisFAERS: 1OFFSIDES
US FAERS
76StressFAERS: 1US FAERS
77Suicide attemptFAERS: 1US FAERS
78Supraventricular tachycardiaFAERS: 1US FAERS
79SwellingFAERS: 1US FAERS
80Unevaluable eventFAERS: 1US FAERS
81Abdominal discomfortOFFSIDES
82Activated Protein C Resistance11301170CTD
83Amenorrhea2576255CTD
84AngerOFFSIDES
85Angle Closure GlaucomaOFFSIDES
86AnhidrosisOFFSIDES
87Ankylosing spondylitisOFFSIDES
88Antiphospholipid SyndromeOFFSIDES
89ApathyOFFSIDES
90AsthenopiaOFFSIDES
91Atrial tachycardiaOFFSIDES
92AuraOFFSIDES
93Biliary dilatationOFFSIDES
94Blood cholesterol abnormalOFFSIDES
95Blood cholesterolOFFSIDES
96Blood follicle stimulating hormone increasedOFFSIDES
97Breast tendernessSIDER
98BruxismOFFSIDES
99CataractSIDER
100Chest PainOFFSIDES
101ChloasmaSIDER
102Choking sensationOFFSIDES
103CholecystitisOFFSIDES
104ChromaturiaOFFSIDES
105Chronic ulcerative colitisOFFSIDES
106Coagulation factor IX level decreasedOFFSIDES
107Contact lens intoleranceSIDER
108Cytolytic hepatitisOFFSIDES
109Depressed moodOFFSIDES
SIDER
110Depressive disorder7750278CTD
111DermatitisSIDER
112Disturbance in sexual arousalSIDER
113Drug exposure during pregnancyOFFSIDES
114Drug withdrawal headacheOFFSIDES
115Dry skinOFFSIDES
116Dysmenorrhea12499030CTD
117DyspepsiaOFFSIDES
118Dysthymic DisorderOFFSIDES
119Emotional disorderOFFSIDES
120Eosinophilic myocarditisOFFSIDES
121EpistaxisOFFSIDES
122Erythema MultiformeSIDER
123Erythema NodosumSIDER
124ErythemaOFFSIDES
125Factor IX inhibitionOFFSIDES
126FatigueOFFSIDES
127Fatty LiverOFFSIDES
128FlatulenceOFFSIDES
129FormicationOFFSIDES
130Gastrointestinal PainSIDER
131Growth of eyelashesOFFSIDES
132HirsutismSIDER
133HypertrichosisOFFSIDES
134HypophagiaOFFSIDES
135ImpatienceOFFSIDES
136Increased upper airway secretionOFFSIDES
137Infectious MononucleosisOFFSIDES
138Injection site dermatitisOFFSIDES
139Injection site erythemaOFFSIDES
140Intention tremorOFFSIDES
141Intracranial HypotensionOFFSIDES
142Iris hyperpigmentationOFFSIDES
143Leukopenia neonatalOFFSIDES
144Live BirthOFFSIDES
145LymphomaOFFSIDES
146MalnutritionSIDER
147Medical device removalOFFSIDES
148Mental impairmentOFFSIDES
149Mesenteric Vascular Occlusion9553191CTD
150Mood swingsSIDER
151Multi-organ disorderOFFSIDES
152Multiple sclerosis relapseOFFSIDES
153Musculoskeletal PainOFFSIDES
154Musculoskeletal chest painOFFSIDES
155Musculoskeletal discomfortOFFSIDES
156Negative thoughtsOFFSIDES
157Nervous tensionOFFSIDES
158Non-cardiac chest painOFFSIDES
159Optic Disc EdemaOFFSIDES
160Ovarian Hyperstimulation SyndromeOFFSIDES
161PROTHROMBIN TIMEOFFSIDES
162Panic DisorderOFFSIDES
163Patellofemoral Pain SyndromeOFFSIDES
164Polycystic Ovary Syndrome2777199CTD
165Poor quality sleepOFFSIDES
166Portal Vein ThrombosisOFFSIDES
167Pregnancy on oral contraceptiveOFFSIDES
168Pulmonary InfarctionOFFSIDES
169RubellaOFFSIDES
170Shunt malfunctionOFFSIDES
171Sinus Thrombosis, Intracranial9593414CTD
172Sleep Initiation and Maintenance Disorders9628521CTD
173Splenic Infarction9553191CTD
OFFSIDES
174Thromboembolism8808016
9553191
CTD
175Thrombophlebitis7750278CTD
OFFSIDES
176TinnitusOFFSIDES
177TonsillitisOFFSIDES
178Unwanted pregnancyOFFSIDES
179UrticariaSIDER
180Vaginal DischargeSIDER
181Vascular Diseases15019538CTD
182Venous Thromboembolism

View details

CTD
183Venous Thrombosis10205088
11463678
CTD
184VomitingSIDER
185Weight Gain11020511CTD
186furuncleOFFSIDES
187nervous system disorderSIDER
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