MetaADEDB 2.0 @ LMMD
Mifepristone
(VKHAHZOOUSRJNA-GCNJZUOMSA-N)
Structure
SMILES
CC#C[C@]1(O)CC[C@@H]2[C@]1(C)C[C@H](c1ccc(cc1)N(C)C)C1=C3CCC(=O)C=C3CC[C@@H]21
Type(s)
Approved; Investigational
ATC code(s)
G03XB01; G03XB51
Molecular Formula:
C29H35NO2
Molecular Weight:
429.594
Log P:
5.4065
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
40.54
CAS Number(s):
83203-42-3; 84371-65-3
Synonym(s)
1.
Mifepristone
2.
Mifegyne
3.
Mifeprex
4.
Mifégyne
5.
R-38486
6.
R38486
7.
RU-38486
8.
RU-486
9.
ZK-98296
10.
ZK98296
11.
R 38486
12.
RU 38486
13.
RU 486
14.
RU38486
15.
RU486
16.
ZK 98296
External Link(s)
MeSHD015735
PubChem Compound55245
BindingDB18723
18627
50072024
ChEBI50692
CHEMBLCHEMBL1276308
DrugBankDB00834
DrugCentral1805
IUPHAR/BPS Guide to PHARMACOLOGY2805
KEGGcpd:C07652
dr:D00585
ZINC3831128
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood potassium decreasedFAERS: 36SIDER
US FAERS
2NauseaFAERS: 35OFFSIDES
SIDER
US FAERS
3FatigueFAERS: 29SIDER
US FAERS
4Product use issueFAERS: 23US FAERS
5HeadacheFAERS: 22SIDER
US FAERS
6PneumoniaFAERS: 21US FAERS
7MalaiseFAERS: 18SIDER
US FAERS
8VomitingFAERS: 17SIDER
US FAERS
9PainFAERS: 15OFFSIDES
SIDER
US FAERS
10Weight decreasedFAERS: 15US FAERS
11Blood creatinine increasedFAERS: 11US FAERS
12Myocardial InfarctionFAERS: 11US FAERS
13Peripheral swellingFAERS: 11US FAERS
14ArthralgiaFAERS: 9SIDER
US FAERS
15Drug ineffectiveFAERS: 9US FAERS
16Urinary tract infectionFAERS: 9US FAERS
17Feeling abnormalFAERS: 8SIDER
US FAERS
18TremorFAERS: 8US FAERS
19Abdominal PainFAERS: 7SIDER
US FAERS
20AlopeciaFAERS: 7US FAERS
21AnxietyFAERS: 7SIDER
US FAERS
22DehydrationFAERS: 7OFFSIDES
US FAERS
23DizzinessFAERS: 7OFFSIDES
SIDER
US FAERS
24Endometrial HyperplasiaFAERS: 7US FAERS
25Inappropriate schedule of drug administrationFAERS: 7US FAERS
26InfectionFAERS: 7OFFSIDES
SIDER
US FAERS
27AstheniaFAERS: 6SIDER
US FAERS
28Blood glucose decreasedFAERS: 6US FAERS
29CellulitisFAERS: 6US FAERS
30Cerebrovascular accidentFAERS: 6US FAERS
31Endometrial thickeningFAERS: 6SIDER
US FAERS
32HypotensionFAERS: 6SIDER
US FAERS
33SepsisFAERS: 6US FAERS
34UrticariaFAERS: 6SIDER
US FAERS
35Blood glucose increasedFAERS: 5US FAERS
36Chest PainFAERS: 5US FAERS
37Drug dose omissionFAERS: 5US FAERS
38Endometrial hypertrophyFAERS: 5SIDER
US FAERS
39SomnolenceFAERS: 5SIDER
US FAERS
40Unevaluable eventFAERS: 5US FAERS
41Blood potassium increasedFAERS: 4US FAERS
42Blood testosterone increasedFAERS: 4US FAERS
43Blood thyroid stimulating hormone increasedFAERS: 4US FAERS
44BronchitisFAERS: 4US FAERS
45ChillsFAERS: 4SIDER
US FAERS
46DysuriaFAERS: 4US FAERS
47EndometriosisFAERS: 416134523CTD
US FAERS
48HerniaFAERS: 4US FAERS
49HypothyroidismFAERS: 4US FAERS
50SyncopeFAERS: 4US FAERS
51Uterine PolypFAERS: 4US FAERS
52Vaginal DischargeFAERS: 4US FAERS
53Activities of daily living impairedFAERS: 3US FAERS
54Depressed moodFAERS: 3US FAERS
55Feeling jitteryFAERS: 3US FAERS
56Groin infectionFAERS: 3US FAERS
57HypersensitivityFAERS: 3SIDER
US FAERS
58MenorrhagiaFAERS: 3US FAERS
59MyalgiaFAERS: 3SIDER
US FAERS
60NasopharyngitisFAERS: 3SIDER
US FAERS
61NephrolithiasisFAERS: 3US FAERS
62PalpitationsFAERS: 3US FAERS
63Pituitary cancer metastaticFAERS: 3US FAERS
64PresyncopeFAERS: 3US FAERS
65Procedural complicationFAERS: 3US FAERS
66Pulmonary FibrosisFAERS: 3US FAERS
67Respiratory FailureFAERS: 3US FAERS
68SwellingFAERS: 3US FAERS
69TachycardiaFAERS: 3US FAERS
70ThirstFAERS: 3SIDER
US FAERS
71AbasiaFAERS: 2US FAERS
72Acute kidney injuryFAERS: 2US FAERS
73AdenocarcinomaFAERS: 2US FAERS
74Adverse eventFAERS: 2US FAERS
75AngioedemaFAERS: 2SIDER
US FAERS
76AscitesFAERS: 2US FAERS
77Atrial FibrillationFAERS: 2US FAERS
78Back PainFAERS: 2SIDER
US FAERS
79Blood Corticotrophin DecreasedFAERS: 2US FAERS
80Blood testosterone decreasedFAERS: 2US FAERS
81Blood urea increasedFAERS: 2US FAERS
82Bone painFAERS: 2US FAERS
83Burning sensationFAERS: 2US FAERS
84Cardiac assistance device userFAERS: 2US FAERS
85Chest discomfortFAERS: 2US FAERS
86ColectomyFAERS: 2US FAERS
87ConstipationFAERS: 2SIDER
US FAERS
88Cortisol increasedFAERS: 2US FAERS
89DisorientationFAERS: 2US FAERS
90Emotional disorderFAERS: 2US FAERS
91EndometritisFAERS: 2SIDER
US FAERS
92ErythemaFAERS: 2US FAERS
93Fluid overloadFAERS: 2US FAERS
94FlushingFAERS: 2US FAERS
95GoutFAERS: 2US FAERS
96HysterectomyFAERS: 2US FAERS
97LethargyFAERS: 2US FAERS
98LymphadenopathyFAERS: 2US FAERS
99MastitisFAERS: 2US FAERS
100Mental impairmentFAERS: 2US FAERS
101No adverse eventFAERS: 2US FAERS
102Oropharyngeal painFAERS: 2US FAERS
103OsteomyelitisFAERS: 2US FAERS
104PancreatitisFAERS: 2US FAERS
105Product use in unapproved indicationFAERS: 2US FAERS
106PruritusFAERS: 2SIDER
US FAERS
107Renin decreasedFAERS: 2US FAERS
108ShockFAERS: 2US FAERS
109TinnitusFAERS: 2US FAERS
110Uterine CancerFAERS: 2US FAERS
111Vulvovaginal painFAERS: 2US FAERS
112White blood cell count decreasedFAERS: 2US FAERS
113Wrong technique in product usage processFAERS: 2US FAERS
114AbscessFAERS: 1US FAERS
115Acute respiratory failureFAERS: 1US FAERS
116AdrenalectomyFAERS: 1US FAERS
117Adrenocortical carcinomaFAERS: 119289534CTD
US FAERS
118Ankle FractureFAERS: 1US FAERS
119Aortic AneurysmFAERS: 1US FAERS
120AphasiaFAERS: 1US FAERS
121Appendicitis noninfectiveFAERS: 1US FAERS
122ArthritisFAERS: 1US FAERS
123Back disorderFAERS: 1US FAERS
124Bacterial sepsisFAERS: 1US FAERS
125Bipolar DisorderFAERS: 1US FAERS
126BlindnessFAERS: 1US FAERS
127Blood chloride decreasedFAERS: 1US FAERS
128Blood corticotrophin increasedFAERS: 1US FAERS
129Blood cortisol abnormalFAERS: 1US FAERS
130Blood cortisol increasedFAERS: 1US FAERS
131Blood count abnormalFAERS: 1US FAERS
132Blood magnesium decreasedFAERS: 1US FAERS
133Blood pressure fluctuationFAERS: 1US FAERS
134Blood sodium decreasedFAERS: 1US FAERS
135Blood triglycerides increasedFAERS: 1SIDER
US FAERS
136Blood urine presentFAERS: 1US FAERS
137Bronchial secretion retentionFAERS: 1US FAERS
138Cardiac ArrestFAERS: 1US FAERS
139Cardiac stress test abnormalFAERS: 1US FAERS
140Cerebral InfarctionFAERS: 1US FAERS
141Cerebral disorderFAERS: 1US FAERS
142Cervical polypFAERS: 1US FAERS
143CholelithiasisFAERS: 1US FAERS
144Clostridium difficile infectionFAERS: 1US FAERS
145Coital bleedingFAERS: 1US FAERS
146Cold sweatFAERS: 1US FAERS
147ColitisFAERS: 1US FAERS
148Congenital HydrocephalusFAERS: 1US FAERS
149Cortisol free urine increasedFAERS: 1US FAERS
150Croup infectiousFAERS: 1US FAERS
151CryingFAERS: 1US FAERS
152CystitisFAERS: 1US FAERS
153Decreased insulin requirementFAERS: 1US FAERS
154Deep Vein ThrombosisFAERS: 1US FAERS
155Dehydroepiandrosterone decreasedFAERS: 1US FAERS
156Dehydroepiandrosterone increasedFAERS: 1US FAERS
157DeliriumFAERS: 1US FAERS
158Depression suicidalFAERS: 1US FAERS
159DiscomfortFAERS: 1SIDER
US FAERS
160Disease ProgressionFAERS: 1US FAERS
161DiverticulitisFAERS: 1US FAERS
162Drug exposure during pregnancyFAERS: 1OFFSIDES
US FAERS
163DysarthriaFAERS: 1US FAERS
164DysgeusiaFAERS: 1US FAERS
165DyspepsiaFAERS: 1US FAERS
166Ectopic PregnancyFAERS: 1US FAERS
167Electrolyte imbalanceFAERS: 1US FAERS
168EncephalitisFAERS: 1US FAERS
169Endometrial adenocarcinomaFAERS: 1US FAERS
170Endometrial disorderFAERS: 1OFFSIDES
US FAERS
171EndosalpingiosisFAERS: 1US FAERS
172Erectile dysfunctionFAERS: 1US FAERS
173Facial paralysisFAERS: 118460590CTD
US FAERS
174False negative pregnancy testFAERS: 1US FAERS
175Feeling ColdFAERS: 1US FAERS
176Feeling of body temperature changeFAERS: 1US FAERS
177FlatulenceFAERS: 1US FAERS
178FractureFAERS: 1US FAERS
179GastroenteritisFAERS: 1US FAERS
180General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
181Growing painsFAERS: 1US FAERS
182HirsutismFAERS: 1US FAERS
183HypertrichosisFAERS: 1US FAERS
184Hyporesponsive to stimuliFAERS: 1US FAERS
185HypoxiaFAERS: 1US FAERS
186IncoherentFAERS: 1US FAERS
187Incorrect dose administeredFAERS: 1US FAERS
188InfluenzaFAERS: 1US FAERS
189Intentional product use issueFAERS: 1US FAERS
190Internal injuryFAERS: 1US FAERS
191Intestinal PerforationFAERS: 1US FAERS
192Intracranial AneurysmFAERS: 1US FAERS
193Joint injuryFAERS: 1US FAERS
194Joint swellingFAERS: 1US FAERS
195LeukocytosisFAERS: 1US FAERS
196Lichen PlanusFAERS: 1US FAERS
197Limb discomfortFAERS: 1US FAERS
198Low density lipoprotein increasedFAERS: 1US FAERS
199LymphomaFAERS: 1US FAERS
200Maternal exposure during pregnancyFAERS: 1US FAERS
201Mediastinal massFAERS: 1US FAERS
202MegacolonFAERS: 1US FAERS
203Memory impairmentFAERS: 1US FAERS
204Meniscus injuryFAERS: 1US FAERS
205Metabolic acidosisFAERS: 1OFFSIDES
US FAERS
206Metapneumovirus infectionFAERS: 1US FAERS
207MetrorrhagiaFAERS: 118460590CTD
SIDER
US FAERS
208Motion SicknessFAERS: 1US FAERS
209Musculoskeletal chest painFAERS: 1SIDER
US FAERS
210Musculoskeletal discomfortFAERS: 1SIDER
US FAERS
211MyocarditisFAERS: 1US FAERS
212Neck PainFAERS: 1US FAERS
213NecrosisFAERS: 1US FAERS
214NephritisFAERS: 1US FAERS
215Neurogenic BowelFAERS: 1US FAERS
216Noninfective gingivitisFAERS: 1US FAERS
217OligodipsiaFAERS: 1US FAERS
218OnychomycosisFAERS: 1US FAERS
219Optic nerve infarctionFAERS: 1US FAERS
220Oral candidiasisFAERS: 1US FAERS
221Oxygen supplementationFAERS: 1US FAERS
222Pancreatic carcinomaFAERS: 1US FAERS
223Pelvic PainFAERS: 1US FAERS
224Pericardial effusionFAERS: 1US FAERS
225PerinephritisFAERS: 1US FAERS
226Peritonsillar AbscessFAERS: 1US FAERS
227PetechiaeFAERS: 1US FAERS
228PleurisyFAERS: 1US FAERS
229PneumothoraxFAERS: 1US FAERS
230Poor quality sleepFAERS: 1US FAERS
231Post abortion infectionFAERS: 1US FAERS
232Post procedural complicationFAERS: 1OFFSIDES
US FAERS
233Precancerous cells presentFAERS: 1US FAERS
234PregnancyFAERS: 1US FAERS
235Pulmonary EmbolismFAERS: 1US FAERS
236Pulmonary HypertensionFAERS: 1US FAERS
237PyelonephritisFAERS: 1US FAERS
238RalesFAERS: 1US FAERS
239Rash erythematousFAERS: 1US FAERS
240RetchingFAERS: 1US FAERS
241Retroperitoneal abscessFAERS: 1US FAERS
242Rheumatoid ArthritisFAERS: 1US FAERS
243Ruptured ectopic pregnancyFAERS: 1US FAERS
244Secretion dischargeFAERS: 1US FAERS
245Septic ShockFAERS: 1OFFSIDES
US FAERS
246SplenomegalyFAERS: 1US FAERS
247Steroid withdrawal syndromeFAERS: 1US FAERS
248Streptococcus test positiveFAERS: 1US FAERS
249StridorFAERS: 1US FAERS
250StuporFAERS: 1US FAERS
251Subcutaneous AbscessFAERS: 1US FAERS
252Suicide attemptFAERS: 1US FAERS
253TachyphreniaFAERS: 1US FAERS
254Therapy cessationFAERS: 1US FAERS
255Therapy changeFAERS: 1US FAERS
256ThrombosisFAERS: 1US FAERS
257Tongue bitingFAERS: 1US FAERS
258ToothacheFAERS: 1US FAERS
259Toxic Shock SyndromeFAERS: 1SIDER
US FAERS
260UnderweightFAERS: 1US FAERS
261Unresponsive to stimuliFAERS: 1US FAERS
262Ureteral necrosisFAERS: 1US FAERS
263Uterine abscessFAERS: 1US FAERS
264Uterine spasmFAERS: 1US FAERS
265VertigoFAERS: 1US FAERS
266Visual ImpairmentFAERS: 1US FAERS
267Vulvovaginal mycotic infectionFAERS: 1US FAERS
268jaundiceFAERS: 1US FAERS
269treatment failureFAERS: 1US FAERS
270Abdominal Compartment SyndromeOFFSIDES
271Acute Lung Injury24812154CTD
272Alcoholic IntoxicationOFFSIDES
273AmenorrheaOFFSIDES
274Angina Pectoris11187221CTD
275AnorexiaSIDER
276Blood albumin decreasedOFFSIDES
277Bradycardia11187221
11435005
CTD
278Brain stem thrombosisOFFSIDES
279Carcinoma17545545CTD
280Chemical and Drug Induced Liver Injury22157104
27374722
CTD
281Cocaine-Related Disorders

View details

CTD
282Cushing Syndrome19289534CTD
283DermatitisSIDER
284Embryo Loss15198763CTD
285Erythema NodosumSIDER
286Fatty Liver28717104CTD
287Fetal Death

View details

CTD
288Flank PainSIDER
289Gastrointestinal PainSIDER
290Gestational DiabetesOFFSIDES
291Hemorrhage21757059CTD
292Hepatomegaly28717104CTD
293Hypercholesterolemia27374722CTD
294Hyperprolactinemia2159045
7962471
CTD
295Hypokalemia19289534CTD
296Infarction, Middle Cerebral Artery30229846CTD
297InfestationSIDER
298Inflammation12843254CTD
299Lymphopenia29247675CTD
300MalnutritionSIDER
301Mammary Neoplasms, Experimental20535544CTD
302Micrognathism18460590CTD
303Mobius Syndrome18460590CTD
304Muscle Hypertonia11435005CTD
305Muscle hypotonia18460590CTD
306Muscle necrosisOFFSIDES
307Muscular Atrophy2424746
12721153
CTD
308OligohydramniosOFFSIDES
309OliguriaOFFSIDES
310Ovarian Diseases2159045CTD
311Pelvic Inflammatory DiseaseSIDER
312Pharmaceutical product complaintOFFSIDES
313Pitting edemaSIDER
314Pituitary Diseases2159045CTD
315Reperfusion Injury30229846CTD
316Seizures11187221CTD
317SinusitisSIDER
318Substance Withdrawal Syndrome18341515CTD
319Toxic Epidermal NecrolysisSIDER
320Ultrasound antenatal screenOFFSIDES
321Ultrasound scan abnormalOFFSIDES
322Uterine RuptureSIDER
323Uterine contractions during pregnancySIDER
324Uterine hemorrhage11326931
19215433
CTD
325Ventricular Fibrillation1550429CTD
326nervous system disorderSIDER
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