MetaADEDB 2.0 @ LMMD
Halothane
(BCQZXOMGPXTTIC-UHFFFAOYSA-N)
Structure
SMILES
ClC(C(F)(F)F)Br
Type(s)
Approved; Vet_approved
ATC code(s)
N01AB01
Molecular Formula:
C2HBrClF3
Molecular Weight:
197.382
Log P:
2.5085
Hydrogen Bond Acceptor:
0
Hydrogen Bond Donor:
0
TPSA:
0
CAS Number(s):
151-67-7
Synonym(s)
1.
Halothane
2.
1,1,1-Trifluoro-2-Chloro-2-Bromoethane
3.
Fluothane
4.
Ftorotan
5.
Narcotan
External Link(s)
MeSHD006221
PubChem Compound3562
BindingDB50112212
ChEBI5615
CHEMBLCHEMBL931
DrugBankDB01159
DrugCentral1356
IUPHAR/BPS Guide to PHARMACOLOGY2401
KEGGcpd:C07515
dr:D00542
Therapeutic Target DatabaseD0D8VE
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Hepatic EncephalopathyFAERS: 2

View details

3676056
5652715
8023596
16085447
 		CTD
US FAERS
2Abdominal PainFAERS: 1US FAERS
3ArthralgiaFAERS: 18533932CTD
US FAERS
4Drug toxicityFAERS: 1US FAERS
5Hepatic necrosisFAERS: 1
Canada Vigilance: 7		Canada Vigilance
US FAERS
6Hepatorenal SyndromeFAERS: 1US FAERS
7Mental status changesFAERS: 1US FAERS
8Pulmonary congestionFAERS: 1US FAERS
9SplenomegalyFAERS: 1US FAERS
10jaundiceFAERS: 1
Canada Vigilance: 19

View details

984517
1035409
2328184
4817369
 		CTD
Canada Vigilance
US FAERS
11Abnormalities, Drug-Induced1193030CTD
12Acidosis3742323CTD
13Acute kidney injury

View details

1036673
2810719
3581528
3811809
5652715
5725736
6718773
7214751
7222320
8239035
16085447
 		CTD
14Alanine Aminotransferase IncreasedCanada Vigilance: 1Canada Vigilance
15Anemia5445639CTD
16Anuria4817369CTD
17Apnea11726412CTD
18Arterial Occlusive Diseases8457053CTD
19Aspartate Aminotransferase IncreasedCanada Vigilance: 3Canada Vigilance
20Asphyxia235749CTD
21AstheniaCanada Vigilance: 1Canada Vigilance
22Asthma11782125CTD
23Azotemia4465472CTD
24Blood alkaline phosphatase increasedCanada Vigilance: 2Canada Vigilance
25Blood lactate dehydrogenase increasedCanada Vigilance: 1Canada Vigilance
26Bradycardia

View details

1239221
1678901
1867419
3970347
8958495
 		CTD
27Brain Diseases612446
4370690		CTD
28Brain Injuries10928976CTD
29BronchospasmCanada Vigilance: 1Canada Vigilance
30Cardiac ArrestCanada Vigilance: 1Canada Vigilance
31Cardiac Output, High1267206CTD
32Chemical and Drug Induced Liver Injury

View details

612446
1597360
3086971
3187193
3811809
3862324
4130893
4479092
4816183
4822274
4822375
4860831
5445639
5534410
5652715
6724195
7214751
7222320
7377592
7427187
7899258
8055607
8533932
9638441
11394653
11873055
12919722
14986543
16165719
17288858
19633216
21245496
21501669
22157104
24747151
 		CTD
33ChillsCanada Vigilance: 44479092
5725736		CTD
Canada Vigilance
34CholecystitisCanada Vigilance: 1Canada Vigilance
35CholelithiasisCanada Vigilance: 1Canada Vigilance
36Cholestasis2262845CTD
37ChromaturiaCanada Vigilance: 2Canada Vigilance
38Enzyme abnormalityCanada Vigilance: 2Canada Vigilance
39EosinophiliaCanada Vigilance: 24479092CTD
Canada Vigilance
40FatigueCanada Vigilance: 4Canada Vigilance
41Fatty Liver995273
6613602
11230718		CTD
42Fetal Diseases235749CTD
43Fever

View details

4479092
4816183
5725736
7284224
8533932
 		CTD
44Granuloma5448336CTD
45Halothane Hepatitis4036534CTD
46Headache5354796
5645764
9689271		CTD
47Heart Block10497454CTD
48Heart Diseases378019
848709		CTD
49Heart failure626424
4026787		CTD
50Hepatitis ACanada Vigilance: 1Canada Vigilance
51Hepatitis, Chronic4412436
6628838		CTD
52HepatitisCanada Vigilance: 24

View details

81359
120824
277092
434688
477040
539329
559436
677583
856877
960004
984517
1012282
1069114
1131552
1259192
1455611
1459138
1554130
1703476
1768541
2145134
2262845
2301746
2325253
2328184
2373140
2490933
2607125
2790555
2810719
2911577
3109584
3192177
3302210
3349642
3369720
3405528
3438542
3676056
3728930
3769709
3811796
3862324
4029887
4058523
4065821
4115160
4634876
4684624
4742362
4772805
4780415
4822274
4852220
5101350
5284553
5448336
5809678
6368059
6671485
6732154
6991940
7026342
7066130
7084806
7119369
7207555
7328735
7463474
7506644
7519986
7647582
8105217
8210981
8216376
8292737
8351144
8363272
8406360
8431608
8554940
8720358
8902272
9259724
9442277
9710415
9744689
9877205
14986543
15715133
18785286
19121848
20124411
 		CTD
Canada Vigilance
53HepatotoxicityCanada Vigilance: 3Canada Vigilance
54Hyperalgesia612445
10910869		CTD
55Hyperemia8214724
11004044
16256270		CTD
56Hyperkalemia3742323
8069990		CTD
57HypotensionCanada Vigilance: 1

View details

235749
236705
414772
581779
747703
842872
932738
1170439
1201159
1239221
1969772
2003305
2117986
2387164
2718706
2831758
2894212
2930005
3281763
3389567
3584265
3756030
3811806
3826855
4186181
4281313
4625631
4706749
4759658
4811207
5064013
5091110
5390083
5396413
5882831
6013323
6020977
6097659
6151891
6614523
7086511
7091390
7124311
7139398
7158277
7237217
7328742
7352670
7403160
7420145
7543620
7553996
7640125
7864443
8069990
8202986
8457053
8912258
11782125
15694917
16256270
19652455
 		CTD
Canada Vigilance
58Infarction, Middle Cerebral Artery17197033CTD
59Kidney Diseases612446
1193030		CTD
60Liver Cirrhosis6628838CTD
61Liver Failure, Acute

View details

4465472
8023596
8354525
9744690
16085447
17288858
18664874
 		CTD
62Liver Failure6392423CTD
63Liver diseases

View details

1035409
1119708
2589676
2818932
3689669
5595515
5757486
6008975
6141900
6685305
7286784
7817129
 		CTD
64Massive Hepatic Necrosis5725736CTD
65Movement Disorders3713967CTD
66Muscle Rigidity

View details

1519800
5026280
5440755
7284224
8059048
 		CTD
67MyalgiaCanada Vigilance: 1Canada Vigilance
68Myocardial Ischemia1467104
1824584
7887099		CTD
69Myoglobinuria7284224CTD
70NauseaCanada Vigilance: 2Canada Vigilance
71Necrosis

View details

1352749
6613602
6711842
6724195
7377592
16965849
 		CTD
72Neutropenia398128CTD
73Oliguria4465472CTD
74Pain10910869CTD
75Postoperative Complications6696217CTD
76Prenatal Exposure Delayed Effects612445
3713966
3713967		CTD
77Quadriplegia1352749
2145134		CTD
78Renal Insufficiency8023596CTD
79Respiratory Insufficiency626424
8023596		CTD
80Respiratory arrestCanada Vigilance: 1Canada Vigilance
81Rhabdomyolysis7284224
8069990		CTD
82Seizures5956574CTD
83Sinus Arrest, Cardiac1678901CTD
84Somatosensory Disorders1352749CTD
85Status Asthmaticus2145134CTD
86Status Epilepticus2817458CTD
87Tachycardia, Ventricular

View details

570000
2036697
4738201
6193348
6666527
6943946
12135952
12409973
17546530
 		CTD
88Tachycardia

View details

1267206
2742097
5124743
6498577
6933872
8069990
 		CTD
89Thrombosis2751146CTD
90Torsades de Pointes10749352CTD
91Trismus

View details

2889402
3662083
3742323
6507932
6731899
7055743
8069986
 		CTD
92Ventricular Dysfunction, Left8457053
12411922		CTD
93Ventricular Fibrillation

View details

549440
1239221
2766111
4397376
4738201
6731915
 		CTD
94VomitingCanada Vigilance: 39689271CTD
Canada Vigilance
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