MetaADEDB 2.0 @ LMMD
Dexmedetomidine
(CUHVIMMYOGQXCV-NSHDSACASA-N)
Structure
SMILES
Cc1cccc(c1C)[C@@H](c1cnc[nH]1)C
Type(s)
Approved; Vet_approved
ATC code(s)
N05CM18
Molecular Formula:
C13H16N2
Molecular Weight:
200.280
Log P:
3.1783
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
1
TPSA:
28.68
CAS Number(s):
113775-47-6
Synonym(s)
1.
Dexmedetomidine
2.
Dexmedetomidine Hydrochloride
3.
MPV-1440
4.
Precedex
5.
Hydrochloride, Dexmedetomidine
6.
MPV 1440
7.
MPV1440
External Link(s)
MeSHD020927
PubChem Compound5311068
BindingDB50085683
ChEBI4466
CHEMBLCHEMBL778
DrugBankDB00633
DrugCentral835
IUPHAR/BPS Guide to PHARMACOLOGY521
KEGGcpd:C07450
dr:D00514
Therapeutic Target DatabaseD0U3DU
ZINC4632106
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1HypotensionFAERS: 9

View details

1675577
9054252
17060146
18083469
18086064
18154474
19682844
24717468
 		CTD
SIDER
US FAERS
2BradycardiaFAERS: 8
Canada Vigilance: 1

View details

7943770
12749653
18083469
18086064
18331550
18363626
18794167
19224802
19682844
19786862
19947809
24571687
24717468
 		CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
3TachycardiaFAERS: 69054252CTD
SIDER
US FAERS
4Cardiac ArrestFAERS: 5SIDER
US FAERS
5AgitationFAERS: 4SIDER
US FAERS
6Anaphylactic shockFAERS: 4US FAERS
7Drug withdrawal convulsionsFAERS: 4US FAERS
8Respiratory DepressionFAERS: 4SIDER
US FAERS
9AnxietyFAERS: 3SIDER
US FAERS
10Drug administered to patient of inappropriate ageFAERS: 2US FAERS
11Intestinal Pseudo-ObstructionFAERS: 2US FAERS
12PolyuriaFAERS: 2US FAERS
13Product use issueFAERS: 2US FAERS
14Skin lesionFAERS: 2US FAERS
15Supraventricular tachycardiaFAERS: 2SIDER
US FAERS
16Upper airway obstructionFAERS: 2US FAERS
17Urinary IncontinenceFAERS: 2US FAERS
18Abdominal PainFAERS: 1SIDER
US FAERS
19Angina PectorisFAERS: 1US FAERS
20Atrial FibrillationFAERS: 1SIDER
US FAERS
21Atrioventricular BlockFAERS: 1SIDER
US FAERS
22Back PainFAERS: 1US FAERS
23Blood creatine phosphokinase increasedFAERS: 1US FAERS
24Bronchoscopy abnormalFAERS: 1US FAERS
25Diabetes InsipidusFAERS: 1US FAERS
26Drug DependenceFAERS: 1US FAERS
27Drug ineffectiveFAERS: 1SIDER
US FAERS
28Drug withdrawal syndromeFAERS: 1US FAERS
29Electrolyte imbalanceFAERS: 1SIDER
US FAERS
30HyperventilationFAERS: 1US FAERS
31HypoxiaFAERS: 1SIDER
US FAERS
32IleusFAERS: 1US FAERS
33Large intestine perforationFAERS: 1US FAERS
34MegacolonFAERS: 1US FAERS
35Muscle SpasticityFAERS: 1US FAERS
36Myocardial InfarctionFAERS: 118086064CTD
SIDER
US FAERS
37Neck PainFAERS: 1US FAERS
38PainFAERS: 112505952
17533423		CTD
SIDER
US FAERS
39Procedural hypotensionFAERS: 1US FAERS
40Respiratory arrestFAERS: 1US FAERS
41RestlessnessFAERS: 1US FAERS
42StridorFAERS: 1US FAERS
43SyncopeFAERS: 1US FAERS
44Troponin increasedFAERS: 1US FAERS
45Ventricular DysfunctionFAERS: 1US FAERS
46Ventricular FibrillationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
47Weaning failureFAERS: 1US FAERS
48WheezingFAERS: 1SIDER
US FAERS
49Abnormal visionSIDER
50AcidosisSIDER
51Acute Coronary SyndromeSIDER
52Acute Lung Injury30102002CTD
53Alanine Aminotransferase IncreasedOFFSIDES
SIDER
54Anoxic EncephalopathyOFFSIDES
55Apnea20055202CTD
56ArteriosclerosisOFFSIDES
57AscitesOFFSIDES
58Aspartate Aminotransferase IncreasedSIDER
59Aspartate aminotransferase abnormalOFFSIDES
60AtaxiaOFFSIDES
61AtelectasisOFFSIDES
SIDER
62AutomatismOFFSIDES
63Beta 2 microglobulin increasedOFFSIDES
64Blood albumin decreasedOFFSIDES
65Blood alkaline phosphatase increasedSIDER
66Blood cholesterolOFFSIDES
67Blood magnesium increasedOFFSIDES
68Blood potassium increasedOFFSIDES
69Blood pressure fluctuationSIDER
70Blood urea increasedOFFSIDES
SIDER
71Blood uric acid decreasedOFFSIDES
72Brain DeathOFFSIDES
73BronchospasmSIDER
74Carbon dioxide increasedSIDER
75Cardiac TamponadeOFFSIDES
76Cardiac perforationOFFSIDES
77Cardiac procedure complicationOFFSIDES
78Chemical and Drug Induced Liver Injury25242406
30597158		CTD
79ChillsSIDER
80Circumstance or information capable of leading to medication errorOFFSIDES
81Cognition Disorders19352168
29723264		CTD
82Conjunctival depositOFFSIDES
83ConstipationSIDER
84Delirium

View details

16324031
18073360
19567759
19786862
 		CTD
SIDER
85Depressive disorder18625256CTD
86DermatitisSIDER
87Diastolic hypertensionSIDER
88DizzinessSIDER
89Drug Overdose15039474CTD
90EcholaliaOFFSIDES
91EczemaOFFSIDES
92Electromechanical dissociationOFFSIDES
93ErythemaOFFSIDES
94Erythroblast count increasedOFFSIDES
95Feeling abnormalSIDER
96Fluid overloadSIDER
97Gamma-Glutamyltransferase IncreasedSIDER
98Gastrointestinal PainSIDER
99GlossoptosisOFFSIDES
100Headache18331550CTD
SIDER
101Heart Block18323319CTD
102Hyperalgesia15220790CTD
103HypercapniaSIDER
104HyperpyrexiaSIDER
105Hypertension worsenedSIDER
106HypoventilationSIDER
107InfarctionSIDER
108InfectionSIDER
109LeukocytosisSIDER
110Long QT Syndrome18323319CTD
111Lymphocyte stimulation test positiveOFFSIDES
112MalnutritionSIDER
113MediastinitisOFFSIDES
114Memory Disorders19352168CTD
115Metabolic acidosisSIDER
116Metamyelocyte percentage increasedOFFSIDES
117Monocyte percentage increasedOFFSIDES
118MonoplegiaOFFSIDES
119Moyamoya DiseaseOFFSIDES
120Muscle Rigidity2569282
9054252		CTD
121Muscle necrosisOFFSIDES
122Myocardial Ischemia8949826
18086064		CTD
123Myoclonus20018300CTD
124NauseaSIDER
125Nephrogenic Diabetes InsipidusOFFSIDES
126NeuralgiaSIDER
127NeuritisSIDER
128Neuroleptic Malignant SyndromeOFFSIDES
129NystagmusOFFSIDES
130OliguriaOFFSIDES
SIDER
131PROTHROMBIN TIMEOFFSIDES
132Pain, Postoperative

View details

10594409
17607500
18083469
19468643
19786862
20610555
 		CTD
133PeritonitisOFFSIDES
134Pharyngolaryngeal PainSIDER
135PneumoniaSIDER
136PneumothoraxSIDER
137Post procedural complicationOFFSIDES
138Postoperative Complications16243902
18086064
19567759		CTD
139PregnancySIDER
140Procedural complicationOFFSIDES
141Protein total decreasedOFFSIDES
142Psychomotor Agitation19947809CTD
143Pulmonary Edema30102002CTD
144Pulmonary congestionSIDER
145Pulmonary function test decreasedSIDER
146Respiratory FailureOFFSIDES
SIDER
147Respiratory Insufficiency20055202CTD
148Respiratory tract congestionSIDER
149Retinopathy of PrematurityOFFSIDES
150SepsisSIDER
151Septic ShockSIDER
152Sinus TachycardiaSIDER
153Sleep Apnea, Central16243902CTD
154SomnolenceSIDER
155Substance Withdrawal Syndrome12552220
17122286
18095980		CTD
156Systolic hypertensionSIDER
157ThirstSIDER
158ThrombocytopeniaSIDER
159Urea increasedSIDER
160Urinary tract infectionSIDER
161Vasospasm, Intracranial20381357CTD
162Ventricular arrhythmiaSIDER
163Visual ImpairmentSIDER
164VomitingSIDER
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