MetaADEDB 2.0 @ LMMD
Pentazocine
(VOKSWYLNZZRQPF-GDIGMMSISA-N)
Structure
SMILES
CC(=CCN1CC[C@@]2([C@H]([C@H]1Cc1c2cc(cc1)O)C)C)C
Type(s)
Approved; Vet_approved
ATC code(s)
N02AD01
Molecular Formula:
C19H27NO
Molecular Weight:
285.424
Log P:
3.8205
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
23.47
CAS Number(s):
359-83-1; 7488-49-5
Synonym(s)
1.
Pentazocine
2.
Fortral
3.
Lexir
4.
Pentazocine Hydrochloride
5.
Pentazocine Lactate
6.
Talwin
7.
Hydrochloride, Pentazocine
8.
Lactate, Pentazocine
External Link(s)
MeSHD010423
PubChem Compound441278
BindingDB50001028
ChEBI7982
CHEMBLCHEMBL560
DrugBankDB00652
IUPHAR/BPS Guide to PHARMACOLOGY1606
KEGGcpd:C07421
dr:D00498
Therapeutic Target DatabaseD0W6DG
ZINC596
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug DependenceFAERS: 3SIDER
US FAERS
2Skin UlcerFAERS: 36538308
8877940		CTD
US FAERS
3Cerebral InfarctionFAERS: 2US FAERS
4Drug abuseFAERS: 2US FAERS
5FibromyalgiaFAERS: 2US FAERS
6Activities of daily living impairedFAERS: 1US FAERS
7Arterial InjuryFAERS: 1US FAERS
8AstheniaFAERS: 1OFFSIDES
SIDER
US FAERS
9Chest discomfortFAERS: 1US FAERS
10ChillsFAERS: 1SIDER
US FAERS
11Depressed moodFAERS: 1US FAERS
12Drug administered at inappropriate siteFAERS: 1US FAERS
13Drug dose omissionFAERS: 1US FAERS
14DysphoniaFAERS: 1OFFSIDES
US FAERS
15DysuriaFAERS: 1US FAERS
16FlushingFAERS: 1SIDER
US FAERS
17MalaiseFAERS: 1US FAERS
18Moyamoya DiseaseFAERS: 1US FAERS
19NauseaFAERS: 1
Canada Vigilance: 1

View details

4272506
5420610
5423846
5556861
6111570
9197945
19671086
 		CTD
SIDER
Canada Vigilance
US FAERS
20OverdoseFAERS: 1OFFSIDES
US FAERS
21PapuleFAERS: 1US FAERS
22PhotophobiaFAERS: 1US FAERS
23QuadriplegiaFAERS: 1US FAERS
24RosaceaFAERS: 1US FAERS
25SomnolenceFAERS: 1SIDER
US FAERS
26Tongue blisteringFAERS: 1US FAERS
27Urinary tract infectionFAERS: 1US FAERS
28White blood cell count decreasedFAERS: 1US FAERS
29Wound InfectionFAERS: 1US FAERS
30Wound necrosisFAERS: 1US FAERS
31Abdominal Pain4272506
12432208		CTD
OFFSIDES
32Abdominal cavity drainageOFFSIDES
33Abdominal discomfortSIDER
34Abdominal distressSIDER
35Acidosis, Respiratory5423846CTD
36Acquired diaphragmatic eventrationOFFSIDES
37Acute graft versus host disease in intestineOFFSIDES
38Acute respiratory failureOFFSIDES
39Adrenal cortex necrosisOFFSIDES
40Adverse eventOFFSIDES
41AgitationSIDER
42AgranulocytosisSIDER
43Airway Obstruction7586106CTD
44Alanine Aminotransferase IncreasedOFFSIDES
45Alcohol consumptionOFFSIDES
46Amnesia5105102CTD
47AmyloidosisOFFSIDES
48Anaphylactic shockSIDER
49AneurysmOFFSIDES
50AnorexiaOFFSIDES
SIDER
51Anticholinergic SyndromeOFFSIDES
52AnxietyOFFSIDES
53Apnea6949303
6961534
7586106		CTD
54Arachnoiditis6477021CTD
55Arteriovenous fistulaOFFSIDES
56Arthralgia6639246CTD
57Arthritis908733CTD
58AscitesOFFSIDES
59Aspiration PneumoniaOFFSIDES
60AtelectasisOFFSIDES
61AutomatismOFFSIDES
62Back Pain4272506
4275009		CTD
63Basal cell carcinomaOFFSIDES
64Bipolar DisorderOFFSIDES
65Blood GlucoseOFFSIDES
66Blood albumin decreasedOFFSIDES
67Blood amylase increasedOFFSIDES
68Blood brain barrier defectOFFSIDES
69Blood creatinine increasedOFFSIDES
70Blood lactate dehydrogenase decreasedOFFSIDES
71Blood lactate dehydrogenase increasedOFFSIDES
72Blood magnesium decreasedOFFSIDES
73Blood parathyroid hormone increasedOFFSIDES
74Blood phosphorus increasedOFFSIDES
75Blood potassium decreasedOFFSIDES
76Blood sodiumOFFSIDES
77Blood urea increasedOFFSIDES
78Blood uric acidOFFSIDES
79BradycardiaOFFSIDES
80Brain AbscessOFFSIDES
81Brain Edema7933514CTD
82Bulbar palsyOFFSIDES
83Calcinosis2105028
9737132		CTD
84Cardiovascular insufficiencySIDER
85Catalepsy10093512CTD
86Catheter related complicationOFFSIDES
87Chest Pain5420610CTD
OFFSIDES
88CholecystitisOFFSIDES
89Circulatory depressionSIDER
90CirrhosisOFFSIDES
91Confusion1123460CTD
92ConstipationSIDER
93Contracture

View details

908733
1172732
4701388
10435175
 		CTD
94Coronary angioplastyOFFSIDES
95Cyanosis5423846CTD
96Cytomegalovirus test positiveOFFSIDES
97Delayed Emergence from Anesthesia5105102
6949303		CTD
98Denervation atrophyOFFSIDES
99Depressed Level of ConsciousnessOFFSIDES
100Depressive disorder1154070
5797194		CTD
101DermatitisSIDER
102Diffuse alveolar damageOFFSIDES
103DiplopiaSIDER
104Disease ProgressionOFFSIDES
105Disease recurrenceOFFSIDES
106Disorders of Excessive Somnolence5423846CTD
107DisorientationSIDER
108Disseminated Intravascular CoagulationOFFSIDES
109Dizziness

View details

375401
4272506
5420610
5423846
5556861
6111570
9197945
 		CTD
SIDER
110Drug Overdose3744788
4093565		CTD
111Drug screen positiveOFFSIDES
112Duodenal ulcer perforationOFFSIDES
113DysgeusiaSIDER
114Electrocardiogram changeOFFSIDES
115Enterobacter sepsisOFFSIDES
116EosinophiliaSIDER
117Erythema MultiformeSIDER
118Euphoric moodSIDER
119Feeling abnormalOFFSIDES
SIDER
120Fetal Growth Retardation3808175CTD
121Fibrosis

View details

126328
508134
908733
1172732
1173609
3800626
4701388
6639246
6885858
8877940
9737132
10435175
12432208
 		CTD
122Gamma-Glutamyltransferase IncreasedOFFSIDES
123Gastric DilatationOFFSIDES
124Gastroenteritis bacillusOFFSIDES
125Gastrointestinal Diseases1123460CTD
126Gastrointestinal infectionOFFSIDES
127Gastrointestinal mucosal disorderOFFSIDES
128Gingival erythemaOFFSIDES
129Glomerulonephritis, Membranoproliferative1316215CTD
130Hallucinations

View details

719349
1123460
4740413
4755007
4819152
4832250
5008496
5394381
5420610
5469859
5556861
5797194
6716360
 		CTD
131Headache

View details

4102363
5556861
6477021
9197945
 		CTD
SIDER
132Hepatic necrosisOFFSIDES
133Herpes zoster infection neurologicalOFFSIDES
134Hip Contracture6885858CTD
135HypersensitivitySIDER
136HypotensionSIDER
137HypoxiaOFFSIDES
138Iatrogenic Disease126328CTD
139Impaired gastric emptyingOFFSIDES
140IndurationSIDER
141InfectionOFFSIDES
142Injection site ulcerOFFSIDES
143Intercostal neuralgiaOFFSIDES
144Intracranial Hypertension6123475CTD
145Joint abscessOFFSIDES
146Kidney FailureOFFSIDES
147Kidney Papillary Necrosis7253164CTD
148Labor Pain5458775CTD
149Leukopenia neonatalOFFSIDES
150LightheadednessSIDER
151Lordosis4701388CTD
152Lymphocyte count decreasedOFFSIDES
153Malignant neoplasm progressionOFFSIDES
154Mental disorders1123460
5456289		CTD
155Miliary pneumoniaOFFSIDES
156Mononeuropathies9737132CTD
157Muscle necrosisOFFSIDES
158Muscular Atrophy6452786
7447890		CTD
159Myocardial Infarction3069539CTD
160NasopharyngitisOFFSIDES
161Neonatal Abstinence Syndrome4275009CTD
162Neonatal respiratory failureOFFSIDES
163Nephritis, Interstitial1316215CTD
164Nephrotic Syndrome1316215CTD
165Neurologic Manifestations5482805CTD
166Neuromuscular Diseases6452786
7447890		CTD
167Neutrophil count decreasedOFFSIDES
168NoduleSIDER
169NystagmusSIDER
170Ocular Motility Disorders8395917CTD
171OliguriaOFFSIDES
172Opioid-Related Disorders1316215CTD
173Osteoarthritis, Spine6477021CTD
174Oxygen supplementationOFFSIDES
175Pain, Postoperative

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375401
5420610
5556861
6614530
 		CTD
176Pain

View details

35781
3233593
3963465
4102363
4930206
5797194
6111570
6132369
6133822
6771831
8395917
9197945
 		CTD
177PallorOFFSIDES
178Pancytopenia4720777CTD
179Paresthesia9197945CTD
180PericarditisOFFSIDES
181Pigmentation Disorders8877940CTD
182Pneumocystis jiroveci pneumoniaOFFSIDES
183Polymyositis8877940CTD
184Polyradiculopathy9737132CTD
185PolyuriaOFFSIDES
186Post procedural bile leakOFFSIDES
187Postoperative Complications6477021CTD
188Postoperative Nausea and Vomiting5105102CTD
189Prenatal Exposure Delayed Effects3808175CTD
190Procedural complicationOFFSIDES
191PruritusCanada Vigilance: 2Canada Vigilance
SIDER
192Psychoses, Substance-Induced1154070
5429189		CTD
193Pulmonary Edema2111555CTD
194Pulmonary Embolism4760023CTD
195Pulmonary HypertensionOFFSIDES
196Pulmonary InfarctionOFFSIDES
197Pulmonary congestionOFFSIDES
198Pulmonary function test decreasedSIDER
199Radial Neuropathy3800626CTD
200Radicular painOFFSIDES
201Respiratory DepressionSIDER
202Respiratory FailureOFFSIDES
203Respiratory Insufficiency3744788
5423846		CTD
204RhabdomyolysisOFFSIDES
205Sciatic Neuropathy508134CTD
206Scleroderma, Limited8915318
9282692		CTD
207Sclerosis1173609
6538308		CTD
208Seizures

View details

1154070
1946581
3744788
4674742
4996737
7201092
18710013
 		CTD
209Septic ShockOFFSIDES
210ShockSIDER
211Shoulder Dislocation908733CTD
212Sick Sinus SyndromeOFFSIDES
213Snoring7586106CTD
214Spondylosis4712825CTD
215Squamous cell carcinoma of skinOFFSIDES
216Stevens-Johnson Syndrome4712825CTD
217Substance Abuse, Intravenous

View details

1173609
1316215
2105028
4701388
6538308
6639246
6885858
12432208
 		CTD
218Substance Withdrawal Syndrome

View details

1154070
2057015
3233593
5420610
 		CTD
219Substance-Related Disorders

View details

1154070
6452786
7166138
7447890
10435175
 		CTD
220Sudden deathOFFSIDES
221SweatingSIDER
222SyncopeSIDER
223Tachycardia5420610CTD
SIDER
224TinnitusSIDER
225Toxic Epidermal NecrolysisSIDER
226TremorCanada Vigilance: 15423846
19671086		CTD
SIDER
Canada Vigilance
227UlcerSIDER
228Uremia1316215
4712825		CTD
229Urinary RetentionSIDER
230Uterine contractions during pregnancySIDER
231Ventricular FibrillationOFFSIDES
232Ventricular hypokinesiaOFFSIDES
233Vertigo5420610
9197945		CTD
SIDER
234Viral DNA test positiveOFFSIDES
235Visual ImpairmentSIDER
236Visual disturbanceSIDER
237Vomiting

View details

4272506
5420610
5556861
6111570
 		CTD
SIDER
238Wound infection staphylococcalOFFSIDES
239Xerostomia5556861
19671086		CTD
240muscle injuryOFFSIDES
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