MetaADEDB 2.0 @ LMMD
Norethindrone acetate and ethinyl estradiol
(GEONECATAKDDLT-JDSZYESASA-N)
Structure
SMILES
C#C[C@@]1(CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2=CC(=O)CC[C@H]12)OC(=O)C.C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCc2c1ccc(c2)O
Molecular Formula:
C42H52O5
Molecular Weight:
636.859
Log P:
7.6759
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
2
TPSA:
83.83
CAS Number(s):
8015-12-1
Synonym(s)
1.
Norethindrone acetate and ethinyl estradiol
External Link(s)
PubChem Compound63020
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1MetrorrhagiaFAERS: 154US FAERS
2Drug ineffectiveFAERS: 91US FAERS
3Product dose omissionFAERS: 80US FAERS
4NauseaFAERS: 71US FAERS
5MenorrhagiaFAERS: 70US FAERS
6HeadacheFAERS: 63US FAERS
7Pulmonary EmbolismFAERS: 63US FAERS
8Drug dose omissionFAERS: 59US FAERS
9Inappropriate schedule of product administrationFAERS: 58US FAERS
10AnxietyFAERS: 51US FAERS
11VomitingFAERS: 43US FAERS
12PregnancyFAERS: 39US FAERS
13Inappropriate schedule of drug administrationFAERS: 37US FAERS
14AlopeciaFAERS: 34US FAERS
15Mood swingsFAERS: 34US FAERS
16Pregnancy on oral contraceptiveFAERS: 34US FAERS
17Product use issueFAERS: 33US FAERS
18ThrombosisFAERS: 33US FAERS
19DizzinessFAERS: 31US FAERS
20Deep Vein ThrombosisFAERS: 29US FAERS
21Recalled product administeredFAERS: 29US FAERS
22Abdominal PainFAERS: 28US FAERS
23AcneFAERS: 28US FAERS
24FatigueFAERS: 26US FAERS
25MalaiseFAERS: 24US FAERS
26PainFAERS: 24US FAERS
27UrticariaFAERS: 24US FAERS
28Cerebrovascular accidentFAERS: 23US FAERS
29Wrong technique in product usage processFAERS: 22US FAERS
30Chest PainFAERS: 20US FAERS
31Feeling abnormalFAERS: 18US FAERS
32PruritusFAERS: 15US FAERS
33CryingFAERS: 14US FAERS
34Therapeutic response unexpectedFAERS: 14US FAERS
35Breast tendernessFAERS: 13US FAERS
36Maternal exposure timing unspecifiedFAERS: 13US FAERS
37PalpitationsFAERS: 12US FAERS
38Product use in unapproved indicationFAERS: 12US FAERS
39Vaginal DischargeFAERS: 12US FAERS
40Abdominal discomfortFAERS: 11US FAERS
41Drug ineffective for unapproved indicationFAERS: 11US FAERS
42Incorrect dose administeredFAERS: 11US FAERS
43Product substitution issueFAERS: 11US FAERS
44Drug exposure during pregnancyFAERS: 10US FAERS
45No adverse eventFAERS: 10US FAERS
46HypersensitivityFAERS: 9US FAERS
47Intentional product misuseFAERS: 9US FAERS
48MyalgiaFAERS: 9US FAERS
49Product quality issueFAERS: 9US FAERS
50AstheniaFAERS: 8US FAERS
51FlatulenceFAERS: 8US FAERS
52Weight decreasedFAERS: 8US FAERS
53Expired product administeredFAERS: 7US FAERS
54Hormone level abnormalFAERS: 7US FAERS
55AngerFAERS: 6US FAERS
56Back PainFAERS: 6US FAERS
57CholelithiasisFAERS: 6US FAERS
58Coital bleedingFAERS: 6US FAERS
59Drug prescribing errorFAERS: 6US FAERS
60Intentional dose omissionFAERS: 6US FAERS
61Lip swellingFAERS: 6US FAERS
62Adverse eventFAERS: 5US FAERS
63Blood glucose increasedFAERS: 5US FAERS
64Chest discomfortFAERS: 5US FAERS
65ChloasmaFAERS: 5US FAERS
66Depressed moodFAERS: 5US FAERS
67Drug administration errorFAERS: 5US FAERS
68Emotional disorderFAERS: 5US FAERS
69LymphadenopathyFAERS: 5US FAERS
70Maternal exposure during breast feedingFAERS: 5US FAERS
71Pulmonary thrombosisFAERS: 5US FAERS
72Urinary tract infectionFAERS: 5US FAERS
73Visual ImpairmentFAERS: 5US FAERS
74jaundiceFAERS: 5US FAERS
75Emotional distressFAERS: 4US FAERS
76FlushingFAERS: 4US FAERS
77Joint swellingFAERS: 4US FAERS
78Memory impairmentFAERS: 4US FAERS
79Musculoskeletal PainFAERS: 4US FAERS
80NervousnessFAERS: 4US FAERS
81ParanoiaFAERS: 4US FAERS
82Product storage errorFAERS: 4US FAERS
83SwellingFAERS: 4US FAERS
84ArthralgiaFAERS: 3US FAERS
85Bipolar DisorderFAERS: 3US FAERS
86Cerebral ThrombosisFAERS: 3US FAERS
87DyspepsiaFAERS: 3US FAERS
88EndometriosisFAERS: 3US FAERS
89ErythemaFAERS: 3US FAERS
90Impaired work abilityFAERS: 3US FAERS
91Intentional product use issueFAERS: 3US FAERS
92Irritable Bowel SyndromeFAERS: 3US FAERS
93LethargyFAERS: 3US FAERS
94Limb discomfortFAERS: 3US FAERS
95Medication ErrorFAERS: 3US FAERS
96Mental status changesFAERS: 3US FAERS
97Neck PainFAERS: 3US FAERS
98Night sweatsFAERS: 3US FAERS
99PallorFAERS: 3US FAERS
100Pelvic PainFAERS: 3US FAERS
101Pharmaceutical product complaintFAERS: 3US FAERS
102Product administration errorFAERS: 3US FAERS
103Product packaging issueFAERS: 3US FAERS
104Rash erythematousFAERS: 3US FAERS
105Suicide attemptFAERS: 3US FAERS
106VertigoFAERS: 3US FAERS
107Abdominal rigidityFAERS: 2US FAERS
108Abdominal tendernessFAERS: 2US FAERS
109Accidental exposure to product by childFAERS: 2US FAERS
110Androgenetic AlopeciaFAERS: 2US FAERS
111ArthroscopyFAERS: 2US FAERS
112AstigmatismFAERS: 2US FAERS
113Bacterial VaginosisFAERS: 2US FAERS
114Bladder painFAERS: 2US FAERS
115BlindnessFAERS: 2US FAERS
116Blood prolactin increasedFAERS: 2US FAERS
117Blood thyroid stimulating hormone increasedFAERS: 2US FAERS
118ChillsFAERS: 2US FAERS
119CholestasisFAERS: 2US FAERS
120ChromaturiaFAERS: 2US FAERS
121ConstipationFAERS: 2US FAERS
122CystFAERS: 2US FAERS
123DiscomfortFAERS: 2US FAERS
124Dry skinFAERS: 2US FAERS
125DysarthriaFAERS: 2US FAERS
126EructationFAERS: 2US FAERS
127Extra dose administeredFAERS: 2US FAERS
128Eye painFAERS: 2US FAERS
129Food AllergyFAERS: 2US FAERS
130Gastrointestinal PainFAERS: 2US FAERS
131General physical condition abnormalFAERS: 2US FAERS
132Head discomfortFAERS: 2US FAERS
133HepatotoxicityFAERS: 2US FAERS
134HypophagiaFAERS: 2US FAERS
135Inappropriate affectFAERS: 2US FAERS
136Incorrect product dosage form administeredFAERS: 2US FAERS
137InfluenzaFAERS: 2US FAERS
138KeratomileusisFAERS: 2US FAERS
139MalnutritionFAERS: 2US FAERS
140Maternal exposure during pregnancyFAERS: 2US FAERS
141Mental impairmentFAERS: 2US FAERS
142Musculoskeletal chest painFAERS: 2US FAERS
143PancreatitisFAERS: 2US FAERS
144Peripheral swellingFAERS: 2US FAERS
145PneumoniaFAERS: 2US FAERS
146Poor quality sleepFAERS: 2US FAERS
147Pregnancy on contraceptiveFAERS: 2US FAERS
148PresyncopeFAERS: 2US FAERS
149Product appearance confusionFAERS: 2US FAERS
150Product prescribing issueFAERS: 2US FAERS
151Product solubility abnormalFAERS: 2US FAERS
152Product taste abnormalFAERS: 2US FAERS
153Pulmonary InfarctionFAERS: 2US FAERS
154Quality of life decreasedFAERS: 2US FAERS
155Skin irritationFAERS: 2US FAERS
156TachycardiaFAERS: 2US FAERS
157ThirstFAERS: 2US FAERS
158Toxicity to various agentsFAERS: 2US FAERS
159TremorFAERS: 2US FAERS
160Unevaluable eventFAERS: 2US FAERS
161Urinary IncontinenceFAERS: 2US FAERS
162Uterine spasmFAERS: 2US FAERS
163Vascular occlusionFAERS: 2US FAERS
164Venous InsufficiencyFAERS: 2US FAERS
165Venous stenosisFAERS: 2US FAERS
166Visual disturbanceFAERS: 2US FAERS
167AbasiaFAERS: 1US FAERS
168Abnormal weight gainFAERS: 1US FAERS
169Abnormal withdrawal bleedingFAERS: 1US FAERS
170Accidental overdoseFAERS: 1US FAERS
171Activities of daily living impairedFAERS: 1US FAERS
172Acute respiratory failureFAERS: 1US FAERS
173Adnexa uteri painFAERS: 1US FAERS
174Allergic reaction to excipientFAERS: 1US FAERS
175AneurysmFAERS: 1US FAERS
176AngioedemaFAERS: 1US FAERS
177AnorexiaFAERS: 1US FAERS
178Autoimmune hepatitisFAERS: 1US FAERS
179AversionFAERS: 1US FAERS
180Axillary vein thrombosisFAERS: 1US FAERS
181Blood cholesterol increasedFAERS: 1US FAERS
182Blood homocysteine increasedFAERS: 1US FAERS
183Blood iron increasedFAERS: 1US FAERS
184Blood pressure fluctuationFAERS: 1US FAERS
185Blood triglycerides increasedFAERS: 1US FAERS
186Blue Toe SyndromeFAERS: 1US FAERS
187Body temperature fluctuationFAERS: 1US FAERS
188Bone painFAERS: 1US FAERS
189Bowel movement irregularityFAERS: 1US FAERS
190Brain DeathFAERS: 1US FAERS
191Catheter related complicationFAERS: 1US FAERS
192Central nervous system lesionFAERS: 1US FAERS
193CholecystitisFAERS: 1US FAERS
194CholelithotomyFAERS: 1US FAERS
195Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
196ClumsinessFAERS: 1US FAERS
197Cluster HeadacheFAERS: 1US FAERS
198Coagulation factor VIII level increasedFAERS: 1US FAERS
199ColitisFAERS: 1US FAERS
200Contact lens complicationFAERS: 1US FAERS
201Contact lens intoleranceFAERS: 1US FAERS
202Contraindicated product administeredFAERS: 1US FAERS
203Conversion disorderFAERS: 1US FAERS
204CystitisFAERS: 1US FAERS
205DehydrationFAERS: 1US FAERS
206Disease recurrenceFAERS: 1US FAERS
207DissociationFAERS: 1US FAERS
208Drug administered to patient of inappropriate ageFAERS: 1US FAERS
209Drug dispensing errorFAERS: 1US FAERS
210Drug effective for unapproved indicationFAERS: 1US FAERS
211Duodenogastric RefluxFAERS: 1US FAERS
212DyspareuniaFAERS: 1US FAERS
213EcchymosisFAERS: 1US FAERS
214Economic problemFAERS: 1US FAERS
215EpilepsyFAERS: 1US FAERS
216Erythema MultiformeFAERS: 1US FAERS
217Erythema NodosumFAERS: 1US FAERS
218Exposure during breast feedingFAERS: 1US FAERS
219Eye irritationFAERS: 1US FAERS
220Facial PainFAERS: 1US FAERS
221Feeling ColdFAERS: 1US FAERS
222Feeling of body temperature changeFAERS: 1US FAERS
223Fibrin D dimer increasedFAERS: 1US FAERS
224Flank PainFAERS: 1US FAERS
225Food aversionFAERS: 1US FAERS
226Food cravingFAERS: 1US FAERS
227Gait inabilityFAERS: 1US FAERS
228GastritisFAERS: 1US FAERS
229GastroenteritisFAERS: 1US FAERS
230Gastrointestinal bacterial overgrowthFAERS: 1US FAERS
231General physical health deteriorationFAERS: 1US FAERS
232HemiparesisFAERS: 1US FAERS
233HemiplegiaFAERS: 1US FAERS
234HepatitisFAERS: 1US FAERS
235HerniaFAERS: 1US FAERS
236HostilityFAERS: 1US FAERS
237HydrocephalusFAERS: 1US FAERS
238HyperchlorhydriaFAERS: 1US FAERS
239HypothyroidismFAERS: 1US FAERS
240HysterectomyFAERS: 1US FAERS
241Impaired quality of lifeFAERS: 1US FAERS
242In-stent arterial restenosisFAERS: 1US FAERS
243Incorrect drug administration rateFAERS: 1US FAERS
244Incorrect product storageFAERS: 1US FAERS
245IndurationFAERS: 1US FAERS
246InflammationFAERS: 1US FAERS
247Intentional self-injuryFAERS: 1US FAERS
248Intervertebral disc injuryFAERS: 1US FAERS
249Intracranial AneurysmFAERS: 1US FAERS
250Joint injuryFAERS: 1US FAERS
251Joint sprainFAERS: 1US FAERS
252Joint stiffnessFAERS: 1US FAERS
253Joint warmthFAERS: 1US FAERS
254KetoacidosisFAERS: 1US FAERS
255Limb injuryFAERS: 1US FAERS
256Lip exfoliationFAERS: 1US FAERS
257Lobar PneumoniaFAERS: 1US FAERS
258Loss of personal independence in daily activitiesFAERS: 1US FAERS
259Lupus-like syndromeFAERS: 1US FAERS
260Medication residue presentFAERS: 1US FAERS
261MeningitisFAERS: 1US FAERS
262Middle insomniaFAERS: 1US FAERS
263Mouth swellingFAERS: 1US FAERS
264Moyamoya DiseaseFAERS: 1US FAERS
265Multiple SclerosisFAERS: 1US FAERS
266Muscle tightnessFAERS: 1US FAERS
267Musculoskeletal discomfortFAERS: 1US FAERS
268Myocardial InfarctionFAERS: 1US FAERS
269MyopiaFAERS: 1US FAERS
270Negative thoughtsFAERS: 1US FAERS
271NocturiaFAERS: 1US FAERS
272NoduleFAERS: 1US FAERS
273Obsessive thoughtsFAERS: 1US FAERS
274ObstructionFAERS: 1US FAERS
275Oral candidiasisFAERS: 1US FAERS
276Oropharyngeal painFAERS: 1US FAERS
277OtosclerosisFAERS: 1US FAERS
278PancytopeniaFAERS: 1US FAERS
279ParesisFAERS: 1US FAERS
280Patient dissatisfaction with treatmentFAERS: 1US FAERS
281Pelvic fluid collectionFAERS: 1US FAERS
282Peripheral embolismFAERS: 1US FAERS
283PhotophobiaFAERS: 1US FAERS
284Platelet count abnormalFAERS: 1US FAERS
285PneumothoraxFAERS: 1US FAERS
286Poor quality drug administeredFAERS: 1US FAERS
287Poor quality product administeredFAERS: 1US FAERS
288Portal vein stenosisFAERS: 1US FAERS
289Pregnancy test false positiveFAERS: 1US FAERS
290Premenstrual syndromeFAERS: 1US FAERS
291Product blister packaging issueFAERS: 1US FAERS
292Product expiration date issueFAERS: 1US FAERS
293Product formulation issueFAERS: 1US FAERS
294Product label issueFAERS: 1US FAERS
295Product physical consistency issueFAERS: 1US FAERS
296Product physical issueFAERS: 1US FAERS
297Product prescribing errorFAERS: 1US FAERS
298Product use complaintFAERS: 1US FAERS
299Reaction to excipientFAERS: 1US FAERS
300Respiratory FailureFAERS: 1US FAERS
301Respiratory tract congestionFAERS: 1US FAERS
302RhabdomyolysisFAERS: 1US FAERS
303Rotator cuff syndromeFAERS: 1US FAERS
304Ruptured ectopic pregnancyFAERS: 1US FAERS
305ScabFAERS: 1US FAERS
306ScreamingFAERS: 1US FAERS
307Secretion dischargeFAERS: 1US FAERS
308SeromaFAERS: 1US FAERS
309Sjogren's SyndromeFAERS: 1US FAERS
310Skin lacerationFAERS: 1US FAERS
311Skin texture abnormalFAERS: 1US FAERS
312SneezingFAERS: 1US FAERS
313SomnolenceFAERS: 1US FAERS
314Spinal column stenosisFAERS: 1US FAERS
315StomatitisFAERS: 1US FAERS
316SunburnFAERS: 1US FAERS
317Suppressed lactationFAERS: 1US FAERS
318SyncopeFAERS: 1US FAERS
319ThrombocytopeniaFAERS: 1US FAERS
320ThrombophlebitisFAERS: 1US FAERS
321TonsillitisFAERS: 1US FAERS
322TrichorrhexisFAERS: 1US FAERS
323Trisomy 21FAERS: 1US FAERS
324Unresponsive to stimuliFAERS: 1US FAERS
325Unwanted pregnancyFAERS: 1US FAERS
326Viral upper respiratory tract infectionFAERS: 1US FAERS
327Vulvovaginal discomfortFAERS: 1US FAERS
328Vulvovaginal drynessFAERS: 1US FAERS
329Vulvovaginal mycotic infectionFAERS: 1US FAERS
330Vulvovaginal painFAERS: 1US FAERS
331Wrong technique in drug usage processFAERS: 1US FAERS
332nervous system disorderFAERS: 1US FAERS
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