MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Dizocilpine Maleate

(QLTXKCWMEZIHBJ-PJGJYSAQSA-N)

Structure

SMILES: C[C@]12N[C@@H](c3c2cccc3)Cc2c1cccc2.OC(=O)/C=C\C(=O)O
Molecular Formula:: C20H19NO4
Molecular Weight:: 337.369
Log P:: 3.1911
Hydrogen Bond Acceptor:: 5
Hydrogen Bond Donor:: 3
TPSA:: 86.63
CAS Number(s):: 77086-22-7; 121917-57-5

Synonym(s)

Dizocilpine Maleate

Dizocilpine

MK-801

MK 801

MK801

External Link(s)

MeSH	D016291
PubChem Compound	6420042
CHEMBL	CHEMBL344151
KEGG	dr:D03878

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Amnesia	View details 9062690 15364487 15936093 16753898 17565710 18695930 18817854	CTD
2	Anxiety Disorders	24067299	CTD
3	Ataxia	View details 1829839 7630427 7906888 12762595 18239784	CTD
4	Brain Diseases	2159831	CTD
5	Brain Injuries	8750036	CTD
6	Brain Ischemia	1731424 9344559	CTD
7	Catalepsy	View details 1365866 1533339 1829839 2153885 2544900 7710668 8114947 8359205 8720577 8957251 9089667 9286616 9374198 11999899 12762595 14729119 15140647 18446324 20558148	CTD
8	Cocaine-Related Disorders	11385572 15295029	CTD
9	Cognition Disorders	11224288 21211109 21274704	CTD
10	Depressive disorder	21945287	CTD
11	Dyskinesia, Drug-Induced	View details 8106150 8982660 10371652 11999899 18545986	CTD
12	Dystonia	1642462 9374198	CTD
13	Essential Tremor	15765150 19497322	CTD
14	Hearing Loss	8946832	CTD
15	Hyperalgesia	View details 7606458 7908645 9539228 10813554 11516259 11880531 15721164 16507304 16601258 17996026 19996949	CTD
16	Hyperhomocysteinemia	20406136	CTD
17	Hypotension	7724054	CTD
18	Memory Disorders	View details 8035347 12672554 15290004 16406104 18191838 19733250 20403448 22951181	CTD
19	Mental disorders	17426488	CTD
20	Mercury Poisoning, Nervous System	18597911	CTD
21	Morphine Dependence	10208762	CTD
22	Movement Disorders	20079362	CTD
23	Muscle Rigidity	View details 8834096 9286616 9416730 9871435	CTD
24	Muscle hypotonia	1829839	CTD
25	Necrosis	16146070 18597911	CTD
26	Nerve Degeneration	View details 1963345 7795658 9061777 12192617 22980357 28916328	CTD
27	Neurogenic Inflammation	22851351	CTD
28	Neurotoxicity Syndromes	11750908	CTD
29	Pain	View details 10813554 11750907 12161096 15047977 16099101 16601258 18155693 23562495	CTD
30	Paraplegia	8327537	CTD
31	Penile Diseases	1358647	CTD
32	Peripheral Nervous System Diseases	11516259	CTD
33	Personality Disorders	7630427 11927170	CTD
34	Poisoning	16614824	CTD
35	Psychomotor Agitation	24389121	CTD
36	Psychomotor Disorders	21274704	CTD
37	Psychoses, Substance-Induced	8319937	CTD
38	Psychotic Disorders	1534132	CTD
39	Seizures	View details 1280523 1322085 1326092 1329401 1386882 1409814 1446880 1470303 1570902 1665475 1684527 1847729 1897004 1933276 2159831 2217500 2406529 2558775 7728525 7870991 7906888 7906944 7984056 8029253 8112511 8162948 8289593 8327537 8619239 8939481 9061777 9249254 9267778 9339868 9553992 9666168 10215643 10698007 10834088 11218047 11224288 11421588 12376152 12660363 12679146 16962289 17157343 23022509 28916251 28916328 30557575	CTD
40	Status Epilepticus	View details 1933279 2553470 7984056 10430476 11074153 11218825	CTD
41	Stereotypic Movement Disorder	20662826	CTD
42	Substance Withdrawal Syndrome	1533339 2027527 15196794	CTD
43	Substance-Related Disorders	8083816 16210775	CTD
44	Trauma, Nervous System	22722016	CTD
45	Tremor	9369366 11999899	CTD

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