MetaADEDB 2.0 @ LMMD
Nitric Oxide
(MWUXSHHQAYIFBG-UHFFFAOYSA-N)
Structure
SMILES
[N]=O
Type(s)
Approved
ATC code(s)
R07AX01
Molecular Formula:
NO
Molecular Weight:
30.006
Log P:
-0.4471
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
0
TPSA:
17.07
CAS Number(s):
10102-43-9
Synonym(s)
1.
Nitric Oxide
2.
Endogenous Nitrate Vasodilator
3.
Mononitrogen Monoxide
4.
Nitric Oxide, Endothelium-Derived
5.
Nitrogen Monoxide
6.
Endothelium-Derived Nitric Oxide
7.
Monoxide, Mononitrogen
8.
Monoxide, Nitrogen
9.
Nitrate Vasodilator, Endogenous
10.
Nitric Oxide, Endothelium Derived
11.
Oxide, Nitric
12.
Vasodilator, Endogenous Nitrate
External Link(s)
MeSHD009569
PubChem Compound145068
ChEBI16480
CHEMBLCHEMBL1200689
DrugBankDB00435
DrugCentral1948
KEGGcpd:C00533
dr:D00074
Therapeutic Target DatabaseD0A5FM
D0W2BD
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Patent ductus arteriosusFAERS: 4US FAERS
2Neonatal disorderFAERS: 3US FAERS
3Pulmonary HypertensionFAERS: 3OFFSIDES
US FAERS
4Neonatal hypotensionFAERS: 2OFFSIDES
US FAERS
5Device FailureFAERS: 1OFFSIDES
US FAERS
6Device malfunctionFAERS: 1OFFSIDES
US FAERS
7Drug ineffective for unapproved indicationFAERS: 1US FAERS
8HypoperfusionFAERS: 1US FAERS
9HypoxiaFAERS: 111195228CTD
OFFSIDES
US FAERS
10Incorrect dose administeredFAERS: 1US FAERS
11Medication ErrorFAERS: 1US FAERS
12NeutropeniaFAERS: 1US FAERS
13PneumothoraxFAERS: 1OFFSIDES
US FAERS
14Rebound effectFAERS: 1US FAERS
15Respiratory FailureFAERS: 1OFFSIDES
US FAERS
16Respiratory arrestFAERS: 1US FAERS
17SepsisFAERS: 110632965
17138957		CTD
US FAERS
18ThrombocytopeniaFAERS: 1US FAERS
19VomitingFAERS: 1US FAERS
20Abdominal sepsisOFFSIDES
21AcidosisOFFSIDES
22Acute Chest SyndromeOFFSIDES
23Acute Lung Injury8643465CTD
24Adenocarcinoma22214195CTD
25Anal FissureOFFSIDES
26Angina Pectoris1686696CTD
27ApneaOFFSIDES
28Arthritis, Experimental19203382CTD
29Aspiration PneumoniaOFFSIDES
30Asthma16696591
16981460
20123607		CTD
31AtelectasisOFFSIDES
32Atherosclerosis9313622
12677255		CTD
33Atrial tachycardiaOFFSIDES
34AutomatismOFFSIDES
35Bilirubin conjugated increasedOFFSIDES
36Blood GlucoseOFFSIDES
37Blood bilirubin unconjugated increasedOFFSIDES
38BradycardiaOFFSIDES
39Brain Injuries9500967CTD
40Brain Ischemia17564305CTD
41Bronchial Diseases15774269CTD
42Candida sepsisOFFSIDES
43Capillary Leak SyndromeOFFSIDES
44Cardiomyopathies11444916
11589785
12377873		CTD
45Cardiomyopathy neonatalOFFSIDES
46Cardiovascular Diseases17448908
20610621		CTD
47Cardiovirus Infections10609881CTD
48Carotid Stenosis15719180CTD
49Catheter sepsisOFFSIDES
50Cerebral ThrombosisOFFSIDES
51Cerebral cystOFFSIDES
52Cerebral ventricle dilatationOFFSIDES
53Chemical and Drug Induced Liver Injury17391827
17569349		CTD
54Cholestasis12612912
16919318
20626112		CTD
55ChorioamnionitisOFFSIDES
56Chronic sinusitisOFFSIDES
57Circumstance or information capable of leading to medication errorOFFSIDES
58Colitis17449036CTD
59Congenital tricuspid valve incompetenceOFFSIDES
60Coronary Artery Disease19515062CTD
61Craniofacial Abnormalities17676596CTD
62Deafness NeurosensoryOFFSIDES
63Dementia, Vascular17556102CTD
64Device breakageOFFSIDES
65Device leakageOFFSIDES
66Device occlusionOFFSIDES
67Diabetes Mellitus, Experimental12123627CTD
68Disseminated Intravascular CoagulationOFFSIDES
69Drug delivery system malfunctionOFFSIDES
70Drug exposure via breast milkOFFSIDES
71Embryo Loss17676596
23409146		CTD
72EndocarditisOFFSIDES
73Endotracheal intubation complicationOFFSIDES
74Enterococcal sepsisOFFSIDES
75Feeding disorder neonatalOFFSIDES
76Fetal Diseases17993583CTD
77Fetal Hypoxia11988250CTD
78Gastroenteritis12682265CTD
79Gastrointestinal hypomotilityOFFSIDES
80Gastrointestinal stoma complicationOFFSIDES
81General physical health deteriorationOFFSIDES
82Headache Disorders, Primary10960046CTD
83Headache

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10971600
11284996
11554966
18521538
 		CTD
84Hearing Loss12745149CTD
85Hearing aid userOFFSIDES
86Heart Diseases19538020CTD
87HydrocephalusOFFSIDES
88Hyperalgesia

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9593928
10422945
11983324
12208318
16098672
16507304
19794317
 		CTD
89HypercapniaOFFSIDES
90Hyperemia

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1505282
7934020
11156591
12459681
 		CTD
91Hyperplasia15719180CTD
92Hypotension

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8757592
9233905
10075076
10805402
11304496
12126183
19268563
19723511
 		CTD
93Infantile apnoeic attackOFFSIDES
94Inflammation12682265
20417174		CTD
95Intestinal Diseases10210152
11574821
11713966		CTD
96Intestinal ObstructionOFFSIDES
97Intestinal PerforationOFFSIDES
98Kidney Diseases15213268
17391827		CTD
99Late metabolic acidosis of newbornOFFSIDES
100Left atrial dilatationOFFSIDES
101Leishmaniasis17218153CTD
102Liver Cirrhosis, Experimental15962377CTD
103Lung Injury11395602CTD
104Lung consolidationOFFSIDES
105Lung diseases17993583CTD
106Lymphoma16166326CTD
107Manganese Poisoning15010209
18041089
22174044		CTD
108Meconium Aspiration Syndrome10565465
11956051		CTD
109Medical device complicationOFFSIDES
110Metabolic acidosisOFFSIDES
111Methemoglobinemia8179406CTD
112Migraine Disorders

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8241457
8866624
10376166
11701602
12964492
21235591
 		CTD
113Morphine Dependence7538210CTD
114Motor Neuron Disease7885422CTD
115Multiple Sclerosis17437305CTD
116Mycoplasma Infections20179380CTD
117Myocardial Infarction14990356CTD
118Myocardial Ischemia8548910CTD
119Myocardial Reperfusion Injury14990356CTD
120Necrosis

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9240406
10222263
10620138
10807416
10909967
 		CTD
121Neonatal anuriaOFFSIDES
122Neonatal intestinal obstructionOFFSIDES
123Neonatal respiratory acidosisOFFSIDES
124Neonatal respiratory failureOFFSIDES
125Nerve Degeneration

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8298082
9436549
9620083
9710261
9870933
9974133
10203697
10691295
10791088
11324438
11711215
12433056
15469948
16307444
19183270
 		CTD
126Neural Tube Defects17676596CTD
127Neuritis, Autoimmune, Experimental9184692CTD
128Neurobehavioral Manifestations21195143CTD
129Oligospermia29983398CTD
130OliguriaOFFSIDES
131Oxygen saturation increasedOFFSIDES
132Pain19794317CTD
133PallorOFFSIDES
134Parkinson Disease21318773CTD
135Periodontal Diseases24040572CTD
136Peritoneal DialysisOFFSIDES
137PeritonitisOFFSIDES
138Persistent Fetal Circulation Syndrome11407344CTD
139Platelet function test abnormalOFFSIDES
140Pneumonia17450216CTD
141Poisoning15025507CTD
142Primary Graft Dysfunction8179406CTD
143Procedural complicationOFFSIDES
144Pulmonary Edema8643465
19675280		CTD
145Pulmonary arterial pressure increasedOFFSIDES
146Pulmonary hypertensive crisisOFFSIDES
147Pulmonary interstitial emphysema syndromeOFFSIDES
148Renal failure neonatalOFFSIDES
149Reperfusion Injury

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10632965
15367387
16386242
17470888
20863214
23061969
 		CTD
150Respiratory Distress Syndrome, Adult9887718
10075076		CTD
151Retinopathy of PrematurityOFFSIDES
152Right Ventricular HypertrophyOFFSIDES
153Schistosomiasis mansoni9673227CTD
154Scrapie11701772CTD
155Seizures

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1916070
8788450
9222532
9500967
10357070
11140358
12175447
 		CTD
156Septic ShockOFFSIDES
157Spinal Cord Diseases16325979CTD
158Status Epilepticus20149694CTD
159Stem cell transplantOFFSIDES
160Stevens-Johnson Syndrome10620138CTD
161Substance Withdrawal Syndrome

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7538210
7603160
8665066
8957383
9576224
10075076
10422958
11377161
14583322
16917115
18607757
 		CTD
162Suture related complicationOFFSIDES
163Teratozoospermia29983398CTD
164Therapy non-responderOFFSIDES
165Thrombosis9313622
20374946		CTD
166Tinea PedisOFFSIDES
167Varicocele18572859CTD
168Vascular Headaches12964492CTD
169Vascular System Injuries21498876CTD
170Ventricular Fibrillation11098973CTD
171Wound dehiscenceOFFSIDES
172Wrong drug administeredOFFSIDES
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