MetaADEDB 2.0 @ LMMD
Edaravone
(QELUYTUMUWHWMC-UHFFFAOYSA-N)
Structure
SMILES
O=C1CC(=NN1c1ccccc1)C
Type(s)
Approved; Investigational
ATC code(s)
N07XX14
Molecular Formula:
C10H10N2O
Molecular Weight:
174.199
Log P:
1.2998
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
32.67
CAS Number(s):
89-25-8
Synonym(s)
1.
Edaravone
2.
1-Phenyl-3-methyl-5-pyrazolone
3.
3-Methyl-1-phenyl-2-pyrazolin-5-one
4.
Edarabone
5.
MCI 186
6.
MCI-186
7.
Norantipyrine
8.
Norphenazone
9.
Phenylmethylpyrazolone
10.
Radicava
11.
1 Phenyl 3 methyl 5 pyrazolone
12.
3 Methyl 1 phenyl 2 pyrazolin 5 one
13.
MCI186
External Link(s)
MeSHD000077553
PubChem Compound4021
BindingDB50200541
ChEBI31530
CHEMBLCHEMBL290916
DrugBankDB12243
DrugCentral4156
KEGGcpd:C13008
dr:D01552
Therapeutic Target DatabaseD06DLI
ZINC18203737
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 97US FAERS
2Disease ProgressionFAERS: 61US FAERS
3AstheniaFAERS: 39US FAERS
4FatigueFAERS: 38US FAERS
5Therapeutic response unexpectedFAERS: 33US FAERS
6Hospice CareFAERS: 23US FAERS
7Amyotrophic Lateral SclerosisFAERS: 2228522181CTD
US FAERS
8No adverse eventFAERS: 19US FAERS
9Incorrect dose administeredFAERS: 13US FAERS
10AphasiaFAERS: 12US FAERS
11Respiratory FailureFAERS: 12US FAERS
12PneumoniaFAERS: 11US FAERS
13HeadacheFAERS: 10US FAERS
14Cerebral InfarctionFAERS: 6US FAERS
15MalaiseFAERS: 6US FAERS
16DizzinessFAERS: 5US FAERS
17ChillsFAERS: 4US FAERS
18PainFAERS: 4US FAERS
19Product dose omissionFAERS: 4US FAERS
20ThrombosisFAERS: 4US FAERS
21Weight decreasedFAERS: 4US FAERS
22Chest discomfortFAERS: 3US FAERS
23Device related infectionFAERS: 3US FAERS
24DiscomfortFAERS: 3US FAERS
25Drug effect incompleteFAERS: 3US FAERS
26DysphoniaFAERS: 3OFFSIDES
US FAERS
27GastrostomyFAERS: 3US FAERS
28Inappropriate schedule of product administrationFAERS: 3US FAERS
29Infusion site painFAERS: 3US FAERS
30Injection site infectionFAERS: 3US FAERS
31Peripheral swellingFAERS: 3US FAERS
32Product storage errorFAERS: 3US FAERS
33PruritusFAERS: 3US FAERS
34SepsisFAERS: 3US FAERS
35SomnolenceFAERS: 3US FAERS
36Urinary tract infectionFAERS: 3US FAERS
37AphoniaFAERS: 2US FAERS
38Back PainFAERS: 2US FAERS
39Cerebrovascular accidentFAERS: 2US FAERS
40Chest PainFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
41ConstipationFAERS: 2US FAERS
42Device occlusionFAERS: 2US FAERS
43Diabetes InsipidusFAERS: 2US FAERS
44Discontinued product administeredFAERS: 2US FAERS
45Drug dose omissionFAERS: 2US FAERS
46ErythemaFAERS: 2US FAERS
47Feeling abnormalFAERS: 2US FAERS
48FlushingFAERS: 2US FAERS
49MarasmusFAERS: 2US FAERS
50Maternal exposure during pregnancyFAERS: 2US FAERS
51MyalgiaFAERS: 2US FAERS
52Product leakageFAERS: 2US FAERS
53White blood cell count decreasedFAERS: 2US FAERS
54Abdominal PainFAERS: 1US FAERS
55Abdominal discomfortFAERS: 1US FAERS
56AcneFAERS: 1US FAERS
57Adverse eventFAERS: 1US FAERS
58ArthralgiaFAERS: 1US FAERS
59AsthmaFAERS: 1OFFSIDES
US FAERS
60Blood glucose increasedFAERS: 1US FAERS
61Blood potassium increasedFAERS: 1US FAERS
62Blood sodium decreasedFAERS: 1US FAERS
63Carbon dioxide increasedFAERS: 1US FAERS
64Cardiac FlutterFAERS: 1US FAERS
65Catheter site painFAERS: 1US FAERS
66Catheter site pustuleFAERS: 1US FAERS
67Catheter site swellingFAERS: 1US FAERS
68Catheter site thrombosisFAERS: 1US FAERS
69Cerebral hyperperfusion syndromeFAERS: 1US FAERS
70ChokingFAERS: 1US FAERS
71CholangitisFAERS: 1US FAERS
72Complication associated with deviceFAERS: 1US FAERS
73Cystatin C increasedFAERS: 1US FAERS
74CystitisFAERS: 1US FAERS
75DeafnessFAERS: 1US FAERS
76Deep Vein ThrombosisFAERS: 1US FAERS
77DehydrationFAERS: 1US FAERS
78DermatitisFAERS: 1US FAERS
79Device malfunctionFAERS: 1US FAERS
80Device related sepsisFAERS: 1US FAERS
81Device related thrombosisFAERS: 1US FAERS
82DisabilityFAERS: 1US FAERS
83DysarthriaFAERS: 1US FAERS
84DysgeusiaFAERS: 1US FAERS
85DysgraphiaFAERS: 1US FAERS
86DyspepsiaFAERS: 1US FAERS
87EczemaFAERS: 1US FAERS
88Emotional disorderFAERS: 1US FAERS
89Extra dose administeredFAERS: 1US FAERS
90Fibrin increasedFAERS: 1US FAERS
91Flank PainFAERS: 1US FAERS
92FlatulenceFAERS: 1US FAERS
93General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
94GlossitisFAERS: 1US FAERS
95GoutFAERS: 1US FAERS
96Grip strength decreasedFAERS: 1US FAERS
97HypercapniaFAERS: 1US FAERS
98HypersensitivityFAERS: 1US FAERS
99HypersomniaFAERS: 1US FAERS
100HypervigilanceFAERS: 1US FAERS
101HypokinesiaFAERS: 1US FAERS
102HypotensionFAERS: 1US FAERS
103InfluenzaFAERS: 1US FAERS
104Infusion Site ExtravasationFAERS: 1US FAERS
105Injection site irritationFAERS: 1US FAERS
106Injection site painFAERS: 1US FAERS
107Injection site pustuleFAERS: 1US FAERS
108Intentional product use issueFAERS: 1US FAERS
109Jugular vein occlusionFAERS: 1US FAERS
110Living in residential institutionFAERS: 1US FAERS
111LymphopeniaFAERS: 1US FAERS
112Mastication disorderFAERS: 1US FAERS
113Mental status changesFAERS: 1US FAERS
114Metastatic NeoplasmFAERS: 1US FAERS
115MonoparesisFAERS: 1US FAERS
116Musculoskeletal discomfortFAERS: 1US FAERS
117Musculoskeletal stiffnessFAERS: 1US FAERS
118Myasthenia GravisFAERS: 1US FAERS
119NauseaFAERS: 1US FAERS
120Neck PainFAERS: 1US FAERS
121NeutropeniaFAERS: 1US FAERS
122Neutrophil count decreasedFAERS: 1OFFSIDES
US FAERS
123PalpitationsFAERS: 1US FAERS
124Pathogen resistanceFAERS: 1US FAERS
125Productive CoughFAERS: 1US FAERS
126Pulmonary EmbolismFAERS: 1US FAERS
127Rash erythematousFAERS: 1US FAERS
128Reperfusion InjuryFAERS: 1

View details

14654979
15086910
15629865
15948865
16041266
16753835
25422538
 		CTD
US FAERS
129Respiratory DepressionFAERS: 1US FAERS
130Respiratory distressFAERS: 1US FAERS
131Secretion dischargeFAERS: 1US FAERS
132SunburnFAERS: 1US FAERS
133Throat irritationFAERS: 1US FAERS
134Thrombosis in deviceFAERS: 1US FAERS
135TremorFAERS: 1US FAERS
136Unevaluable eventFAERS: 1US FAERS
137UrticariaFAERS: 1US FAERS
138Vascular Access ComplicationFAERS: 1US FAERS
139Vascular device infectionFAERS: 1US FAERS
140Vein collapseFAERS: 1US FAERS
141Vertebral artery aneurysmFAERS: 1US FAERS
142WheezingFAERS: 1US FAERS
143Accidental overdoseOFFSIDES
144Acute kidney injury17498008CTD
145Acute myocardial infarctionOFFSIDES
146Analgesic asthma syndromeOFFSIDES
147AnxietyCanada Vigilance: 1Canada Vigilance
148AtelectasisOFFSIDES
149Blood amylase increasedOFFSIDES
150Blood brain barrier defectOFFSIDES
151Brain AbscessOFFSIDES
152Brain Diseases16784740CTD
153Brain Infarction21040696CTD
154Brain Injuries18672383CTD
155Brain Ischemia18654047CTD
156Carbon Monoxide Poisoning25348283CTD
157Cerebral Hemorrhage19095969CTD
158Depressed Level of ConsciousnessOFFSIDES
159Disseminated Intravascular Coagulation17498008CTD
OFFSIDES
160Edema21040696CTD
161EmbolismOFFSIDES
162Endotoxemia12954792CTD
163EpilepsyOFFSIDES
164Fatty Liver12795759CTD
165Gamma-Glutamyltransferase IncreasedOFFSIDES
166Hearing Loss18607936CTD
167Hematoma18654047CTD
168HemiplegiaOFFSIDES
169Hepatitis17498008CTD
170Hyperglycemia18291360CTD
171InfectionOFFSIDES
172Inflammation18291360
21040696		CTD
173Intracranial Aneurysm19381132CTD
OFFSIDES
174Ischemia16301206CTD
175Joint swellingCanada Vigilance: 1Canada Vigilance
176Kidney Diseases18085390CTD
177Leukopenia neonatalOFFSIDES
178LipaseOFFSIDES
179Low Tension Glaucoma28703795CTD
180Lung Injury21040696CTD
181Metabolic Diseases16301206CTD
182Motor Neuron Disease26469273CTD
183Muscle WeaknessOFFSIDES
184Myocardial ruptureOFFSIDES
185Nephrotic SyndromeOFFSIDES
186Nerve Degeneration16784740
28703795		CTD
187Pancreatitis20035747CTD
188Proteinuria16079985CTD
189Pulmonary Fibrosis21040696CTD
190Retinal Degeneration28703795CTD
191RhabdomyolysisOFFSIDES
192SoliloquyOFFSIDES
193Stevens-Johnson SyndromeOFFSIDES
194Tracheal StenosisOFFSIDES
195Vestibular Diseases12600698CTD
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