MetaADEDB 2.0 @ LMMD
Selegiline
(MEZLKOACVSPNER-GFCCVEGCSA-N)
Structure
SMILES
C[C@@H](N(CC#C)C)Cc1ccccc1
Type(s)
Approved; Investigational; Vet_approved
ATC code(s)
N04BD01
Molecular Formula:
C13H17N
Molecular Weight:
187.281
Log P:
2.1826
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
0
TPSA:
3.24
CAS Number(s):
14611-51-9
Synonym(s)
1.
Selegiline
2.
Deprenalin
3.
Deprenil
4.
Deprenyl
5.
E-250
6.
Eldepryl
7.
Emsam
8.
Humex
9.
Jumex
10.
L-Deprenyl
11.
Selegiline Hydrochloride
12.
Selegiline Hydrochloride, (R)-Isomer
13.
Selegiline Hydrochloride, (R,S)-Isomer
14.
Selegiline Hydrochloride, (S)-Isomer
15.
Selegiline, (R)-Isomer
16.
Selegiline, (R,S)-Isomer
17.
Selegiline, (S)-Isomer
18.
Selegyline
19.
Yumex
20.
Zelapar
21.
E 250
22.
E250
External Link(s)
MeSHD012642
PubChem Compound26757
BindingDB15579
ChEBI9086
CHEMBLCHEMBL972
DrugBankDB01037
DrugCentral2429
IUPHAR/BPS Guide to PHARMACOLOGY6639
KEGGcpd:C07245
dr:D03731
Therapeutic Target DatabaseD0VC5L
D0S2UG
ZINC19632633
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Application site erythemaFAERS: 77OFFSIDES
US FAERS
2Drug ineffectiveFAERS: 65US FAERS
3Application site rashFAERS: 59OFFSIDES
US FAERS
4Application site pruritusFAERS: 47OFFSIDES
US FAERS
5Application site irritationFAERS: 31OFFSIDES
US FAERS
6Application site reactionFAERS: 28OFFSIDES
US FAERS
7HeadacheFAERS: 25US FAERS
8AnxietyFAERS: 22OFFSIDES
US FAERS
9DizzinessFAERS: 22US FAERS
10Application site urticariaFAERS: 21US FAERS
11NauseaFAERS: 17OFFSIDES
US FAERS
12Application site vesiclesFAERS: 12US FAERS
13Product adhesion issueFAERS: 12US FAERS
14AgitationFAERS: 10US FAERS
15Application site painFAERS: 10US FAERS
16FatigueFAERS: 10US FAERS
17Wrong technique in product usage processFAERS: 9US FAERS
18HypersensitivityFAERS: 8US FAERS
19Adverse eventFAERS: 7OFFSIDES
US FAERS
20ErythemaFAERS: 7US FAERS
21Feeling abnormalFAERS: 7US FAERS
22Hypertensive crisisFAERS: 7US FAERS
23Weight decreasedFAERS: 7US FAERS
24Drug screen false positiveFAERS: 6US FAERS
25PainFAERS: 6US FAERS
26TachycardiaFAERS: 6US FAERS
27False positive investigation resultFAERS: 5US FAERS
28Feeling jitteryFAERS: 5US FAERS
29HypotensionFAERS: 5US FAERS
30MyalgiaFAERS: 5US FAERS
31No adverse eventFAERS: 5US FAERS
32PalpitationsFAERS: 5US FAERS
33Product quality issueFAERS: 5US FAERS
34PruritusFAERS: 5US FAERS
35Skin irritationFAERS: 5US FAERS
36Skin reactionFAERS: 5US FAERS
37TremorFAERS: 53670563CTD
US FAERS
38Application site burnFAERS: 4US FAERS
39Application site erosionFAERS: 4US FAERS
40Application site swellingFAERS: 4OFFSIDES
US FAERS
41Incorrect dose administeredFAERS: 4US FAERS
42SomnolenceFAERS: 4US FAERS
43UrticariaFAERS: 4US FAERS
44Application site hypersensitivityFAERS: 3US FAERS
45Application site inflammationFAERS: 3US FAERS
46Application site scarFAERS: 3OFFSIDES
US FAERS
47AstheniaFAERS: 3US FAERS
48Chest PainFAERS: 3US FAERS
49DisorientationFAERS: 3US FAERS
50LacerationFAERS: 3OFFSIDES
US FAERS
51Mood swingsFAERS: 3US FAERS
52Neck PainFAERS: 3US FAERS
53NervousnessFAERS: 3US FAERS
54ParanoiaFAERS: 3US FAERS
55ScreamingFAERS: 3OFFSIDES
US FAERS
56SyncopeFAERS: 3US FAERS
57Urinary tract infectionFAERS: 3US FAERS
58VomitingFAERS: 3US FAERS
59AlopeciaFAERS: 2US FAERS
60Application site dischargeFAERS: 2US FAERS
61Application site exfoliationFAERS: 2US FAERS
62ArthralgiaFAERS: 2US FAERS
63Blood pressure fluctuationFAERS: 2OFFSIDES
US FAERS
64Blood sodium decreasedFAERS: 2US FAERS
65ChillsFAERS: 2US FAERS
66Completed SuicideFAERS: 2US FAERS
67ConstipationFAERS: 2US FAERS
68CryingFAERS: 2US FAERS
69Depressed moodFAERS: 2US FAERS
70Disease recurrenceFAERS: 2US FAERS
71Drug administration errorFAERS: 2US FAERS
72Drug effect incompleteFAERS: 2US FAERS
73Drug screen positiveFAERS: 2OFFSIDES
US FAERS
74DysarthriaFAERS: 2US FAERS
75FlatulenceFAERS: 2US FAERS
76Incorrect drug administration durationFAERS: 2US FAERS
77Joint stiffnessFAERS: 2US FAERS
78Joint swellingFAERS: 2US FAERS
79MalaiseFAERS: 2US FAERS
80Medication ErrorFAERS: 2US FAERS
81Musculoskeletal stiffnessFAERS: 2OFFSIDES
US FAERS
82Myocardial InfarctionFAERS: 2US FAERS
83NeuralgiaFAERS: 2US FAERS
84Nuchal RigidityFAERS: 2OFFSIDES
US FAERS
85Oropharyngeal painFAERS: 2US FAERS
86OverdoseFAERS: 2US FAERS
87Peripheral swellingFAERS: 2US FAERS
88Pharmaceutical product complaintFAERS: 2US FAERS
89PregnancyFAERS: 2US FAERS
90Serotonin SyndromeFAERS: 2US FAERS
91Skin hypertrophyFAERS: 2US FAERS
92TensionFAERS: 2US FAERS
93TinnitusFAERS: 2US FAERS
94Unevaluable eventFAERS: 2US FAERS
95AbasiaFAERS: 1US FAERS
96Abdominal discomfortFAERS: 1US FAERS
97Acute psychosisFAERS: 1US FAERS
98Anaphylactoid ReactionFAERS: 1US FAERS
99AngerFAERS: 1US FAERS
100Angina PectorisFAERS: 1US FAERS
101AngioedemaFAERS: 1US FAERS
102ApathyFAERS: 1US FAERS
103AphoniaFAERS: 1US FAERS
104Application site drynessFAERS: 1US FAERS
105Application site hypertrophyFAERS: 1US FAERS
106Application site lacerationFAERS: 1US FAERS
107Application site papulesFAERS: 1US FAERS
108Application site warmthFAERS: 1US FAERS
109AsphyxiaFAERS: 1US FAERS
110AtaxiaFAERS: 1OFFSIDES
US FAERS
111Autonomic nervous system imbalanceFAERS: 1US FAERS
112Back PainFAERS: 1US FAERS
113Back disorderFAERS: 1US FAERS
114BlepharitisFAERS: 1US FAERS
115BlepharospasmFAERS: 1US FAERS
116BlindnessFAERS: 1US FAERS
117Blood catecholamines increasedFAERS: 1US FAERS
118Blood glucose decreasedFAERS: 1OFFSIDES
US FAERS
119Blood urine presentFAERS: 1US FAERS
120Bone painFAERS: 1US FAERS
121BronchitisFAERS: 1US FAERS
122Burning Mouth SyndromeFAERS: 1US FAERS
123Change in sustained attentionFAERS: 1US FAERS
124CyanosisFAERS: 1OFFSIDES
US FAERS
125DehydrationFAERS: 1OFFSIDES
US FAERS
126DeliriumFAERS: 111154095CTD
US FAERS
127DiplopiaFAERS: 1US FAERS
128DiscomfortFAERS: 1US FAERS
129Disturbance in sexual arousalFAERS: 1US FAERS
130Drug dispensing errorFAERS: 1OFFSIDES
US FAERS
131Drug dose omissionFAERS: 1US FAERS
132Drug effect delayedFAERS: 1US FAERS
133Drug level increasedFAERS: 1US FAERS
134Drug prescribing errorFAERS: 1US FAERS
135Drug withdrawal syndromeFAERS: 1US FAERS
136Dry skinFAERS: 1US FAERS
137DysgeusiaFAERS: 1US FAERS
138DysplasiaFAERS: 1US FAERS
139Economic problemFAERS: 1OFFSIDES
US FAERS
140Erectile dysfunctionFAERS: 1US FAERS
141Expired drug administeredFAERS: 1OFFSIDES
US FAERS
142Expired product administeredFAERS: 1US FAERS
143Eye painFAERS: 1US FAERS
144Feeling ColdFAERS: 1US FAERS
145GlaucomaFAERS: 1US FAERS
146Heat StrokeFAERS: 1US FAERS
147HyperventilationFAERS: 1US FAERS
148HypophagiaFAERS: 1US FAERS
149HypoventilationFAERS: 1US FAERS
150Illogical thinkingFAERS: 1US FAERS
151Impaired driving abilityFAERS: 1US FAERS
152Initial insomniaFAERS: 1US FAERS
153Intentional drug misuseFAERS: 1US FAERS
154Lack of application site rotationFAERS: 1US FAERS
155LeukopeniaFAERS: 1US FAERS
156Memory impairmentFAERS: 1US FAERS
157Mental impairmentFAERS: 1OFFSIDES
US FAERS
158Musculoskeletal PainFAERS: 1OFFSIDES
US FAERS
159MyoclonusFAERS: 1US FAERS
160NasopharyngitisFAERS: 1US FAERS
161Negative thoughtsFAERS: 1US FAERS
162NephrolithiasisFAERS: 1US FAERS
163NystagmusFAERS: 1US FAERS
164Oral candidiasisFAERS: 1US FAERS
165PancytopeniaFAERS: 1US FAERS
166PericarditisFAERS: 1US FAERS
167Personality ChangeFAERS: 1US FAERS
168PetechiaeFAERS: 1US FAERS
169PharyngitisFAERS: 1US FAERS
170PneumoniaFAERS: 1US FAERS
171Poor quality sleepFAERS: 1US FAERS
172Prescribed overdoseFAERS: 1US FAERS
173Product dose omissionFAERS: 1US FAERS
174Product storage errorFAERS: 1US FAERS
175Psychiatric decompensationFAERS: 1US FAERS
176PurulenceFAERS: 1US FAERS
177Quality of life decreasedFAERS: 1US FAERS
178Reaction to drug excipientsFAERS: 1US FAERS
179Respiratory FailureFAERS: 1US FAERS
180RestlessnessFAERS: 1US FAERS
181Sinus headacheFAERS: 1US FAERS
182SinusitisFAERS: 1US FAERS
183Skin UlcerFAERS: 1US FAERS
184Skin lacerationFAERS: 1US FAERS
185Skin lesionFAERS: 1US FAERS
186SluggishnessFAERS: 1US FAERS
187StomatitisFAERS: 1US FAERS
188Suicide attemptFAERS: 1US FAERS
189SwellingFAERS: 1US FAERS
190Therapeutic response unexpectedFAERS: 1US FAERS
191Therapy cessationFAERS: 1US FAERS
192Therapy non-responderFAERS: 1US FAERS
193Thermal burnFAERS: 1US FAERS
194Tongue erythemaFAERS: 1US FAERS
195Toxicity to various agentsFAERS: 1US FAERS
196Tyramine reactionFAERS: 1OFFSIDES
US FAERS
197Unresponsive to stimuliFAERS: 1US FAERS
198Upper-airway cough syndromeFAERS: 1US FAERS
199Urinary RetentionFAERS: 1US FAERS
200Urine amphetamine positiveFAERS: 1US FAERS
201Visual ImpairmentFAERS: 1US FAERS
202nervous system disorderFAERS: 1US FAERS
203Acute respiratory failureOFFSIDES
204Adjustment disorder with depressed moodOFFSIDES
205AgraphiaOFFSIDES
206Alcohol consumptionOFFSIDES
207AmphetaminesOFFSIDES
208AnhedoniaOFFSIDES
209Aspiration PneumoniaOFFSIDES
210AuraOFFSIDES
211Autoimmune thyroiditisOFFSIDES
212Autonomic neuropathyOFFSIDES
213Basal cell carcinomaOFFSIDES
214Basal ganglion degenerationOFFSIDES
215BedriddenOFFSIDES
216Bipolar Disorder1449399CTD
217Blood thyroid stimulating hormone increasedOFFSIDES
218Brain Injuries7953696CTD
219BruxismOFFSIDES
220Catalepsy2960778
12711835		CTD
221Catatonia11980384CTD
222Cerebral artery occlusionOFFSIDES
223CholecystitisOFFSIDES
224Cocaine-Related Disorders10327427
14605792
16425053		CTD
225Cognition Disorders10778622CTD
226DemyelinationOFFSIDES
227Depressed Level of ConsciousnessOFFSIDES
228Drug chemical incompatibilityOFFSIDES
229Drug toxicityOFFSIDES
230Dyskinesia, Drug-Induced71602
1549214		CTD
231Dysthymic DisorderOFFSIDES
232DystoniaOFFSIDES
233Ejection Fraction DecreasedOFFSIDES
234Embolic cerebral infarctionOFFSIDES
235Emotional distressOFFSIDES
236EnterocolitisOFFSIDES
237ExophthalmosOFFSIDES
238GamblingOFFSIDES
239Gastric mucosal lesionOFFSIDES
240Gastric ulcerOFFSIDES
241Hallucinations11154095
15120098		CTD
242Heat illnessOFFSIDES
243HemiplegiaOFFSIDES
244HemothoraxOFFSIDES
245Hepatitis B antibody positiveOFFSIDES
246HypertrichosisOFFSIDES
247Hypertrophic CardiomyopathyOFFSIDES
248Hypokinesia3670563CTD
OFFSIDES
249Hypotension, Orthostatic9285463
10091617
11154095		CTD
250Inspiratory capacity decreasedOFFSIDES
251Joint injuryOFFSIDES
252Lumbar radiculopathyOFFSIDES
253Lung consolidationOFFSIDES
254Medical device complicationOFFSIDES
255Memory Disorders1946572
10778622		CTD
256Micturition frequency decreasedOFFSIDES
257Middle insomniaOFFSIDES
258Mouth BreathingOFFSIDES
259Multiple System AtrophyOFFSIDES
260MurderOFFSIDES
261Muscle Rigidity3670563CTD
262MyelitisOFFSIDES
263Narcissistic Personality DisorderOFFSIDES
264Nephrotic SyndromeOFFSIDES
265Nerve Degeneration16099847
16490285
17136323		CTD
266Neuroleptic Malignant SyndromeOFFSIDES
267Neurologic Manifestations23062100CTD
268Obsessive-Compulsive Disorder16730214CTD
269Parkinson Disease

View details

71602
121706
1549214
2502843
6428144
9285463
9921882
10776749
10776750
10981248
11154095
11199819
17084986
18328768
21777011
21923181
22019741
 		CTD
270Parkinsonian Disorders16490285CTD
271Pheochromocytoma8094789CTD
272PleurisyOFFSIDES
273Pre-existing condition improvedOFFSIDES
274Productive CoughOFFSIDES
275Psychiatric symptomOFFSIDES
276Psychoses, Substance-Induced20620094CTD
277Pulmonary arterial pressure increasedOFFSIDES
278Restrictive pulmonary diseaseOFFSIDES
279RhinalgiaOFFSIDES
280RhinorrheaOFFSIDES
281Seizures9352429CTD
282Sexual activity increasedOFFSIDES
283Sleep Initiation and Maintenance Disorders17017821CTD
284Squamous cell carcinoma of skinOFFSIDES
285Stereotypic Movement Disorder16490285CTD
286Sudden onset of sleepOFFSIDES
287SympathicotoniaOFFSIDES
288Tooth LossOFFSIDES
289Transvestism12151912CTD
290Wound ComplicationOFFSIDES
291Wound infection staphylococcalOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.