tauroursodeoxycholic acid
(BHTRKEVKTKCXOH-LBSADWJPSA-N)
Structure
- SMILES
- O[C@@H]1CC[C@]2([C@@H](C1)C[C@@H]([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)NCCS(=O)(=O)O)C)C)O)C
- Type(s)
- Experimental; Investigational
- Molecular Formula:
- C26H45NO6S
- Molecular Weight:
- 499.704
- Log P:
- 4.8690
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 4
- TPSA:
- 132.31
- CAS Number(s):
- 14605-22-2
Synonym(s)
1.
tauroursodeoxycholic acid
2.
TUDCA
3.
tauroursodeoxycholate
4.
tauroursodeoxycholic acid, (3alpha,5alpha,7alpha)-isomer
5.
tauroursodeoxycholic acid, monosodium salt, (3alpha,5beta,7alpha)-isomer
6.
tauroursodeoxycholic acid, monosodium salt, (3alpha,7alpha)-isomer
External Link(s)
| MeSH | C031655 |
| PubChem Compound | 9848818 |
| BindingDB | 50236230 |
| ChEBI | 80774 |
| CHEMBL | CHEMBL272427 |
| DrugBank | DB08834 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 4746 |
| KEGG | cpd:C16868 |
| Therapeutic Target Database | D03RKW |
| ZINC | 3914813 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Brain Injuries | 12721362 | CTD | |
| 2 | Cerebral Hemorrhage | 12721362 | CTD | |
| 3 | Chemical and Drug Induced Liver Injury | 20797393 | CTD | |
| 4 | Cholestasis | CTD | ||
| 5 | Cognition Disorders | 11573988 | CTD | |
| 6 | Fatty Liver | 24210820 | CTD | |
| 7 | Myocardial Infarction | 17436368 | CTD | |
| 8 | Necrosis | 11450444 | CTD | |
| 9 | Neurobehavioral Manifestations | 12721362 | CTD | |
| 10 | Retinal Degeneration | 17213800 | CTD |
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