MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Bromocriptine

(OZVBMTJYIDMWIL-AYFBDAFISA-N)

Structure

SMILES: CC(C[C@H]1C(=O)N2CCC[C@H]2[C@]2(N1C(=O)[C@@](O2)(NC(=O)[C@H]1CN(C)[C@H]2C(=C1)c1cccc3c1c(C2)c([nH]3)Br)C(C)C)O)C
Type(s): Approved; Investigational
ATC code(s): G02CB01; N04BC01
Molecular Formula:: C32H40BrN5O5
Molecular Weight:: 654.595
Log P:: 3.3974
Hydrogen Bond Acceptor:: 9
Hydrogen Bond Donor:: 3
TPSA:: 118.21
CAS Number(s):: 25614-03-3

Synonym(s)

Bromocriptine

2-Bromoergocryptine

Bromocryptin

2-Bromo-alpha-ergocryptine

2-Bromo-alpha-ergokryptine

2-Bromoergocryptine Mesylate

2-Bromoergocryptine Methanesulfonate

2-Bromoergokryptine

Bromocriptin

10.

Bromocriptine Mesylate

11.

CB-154

12.

Parlodel

13.

2 Bromo alpha ergocryptine

14.

2 Bromo alpha ergokryptine

15.

2 Bromoergocryptine

16.

2 Bromoergocryptine Mesylate

17.

2 Bromoergocryptine Methanesulfonate

18.

2 Bromoergokryptine

19.

CB 154

20.

CB154

21.

Mesylate, 2-Bromoergocryptine

22.

Mesylate, Bromocriptine

23.

Methanesulfonate, 2-Bromoergocryptine

External Link(s)

MeSH	D001971
PubChem Compound	31101
BindingDB	81993 50026707
ChEBI	3181
CHEMBL	CHEMBL493
DrugBank	DB01200
DrugCentral	403
IUPHAR/BPS Guide to PHARMACOLOGY	35
KEGG	cpd:C06856 dr:D03165
Therapeutic Target Database	D06YFA
ZINC	53683151

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Drug ineffective	FAERS: 9		US FAERS
2	Headache	FAERS: 7 Canada Vigilance: 9	View details 1923236 2808744 6454713 6669217 8976978 9296138 12058109	CTD SIDER Canada Vigilance US FAERS
3	Maternal exposure during pregnancy	FAERS: 6		US FAERS
4	Nausea	FAERS: 4 Canada Vigilance: 14	View details 386307 772175 3234463 3503918 6454713 6488683 6507109 6669217 7243095 8959084 11956968	CTD OFFSIDES SIDER Canada Vigilance US FAERS
5	Aortic valve sclerosis	FAERS: 3		US FAERS
6	Cerebral vasoconstriction	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
7	Delirium	FAERS: 3	3671965	CTD SIDER US FAERS
8	General physical health deterioration	FAERS: 3		OFFSIDES US FAERS
9	Insulin-like growth factor increased	FAERS: 3		US FAERS
10	Low birth weight baby	FAERS: 3		US FAERS
11	Somnolence	FAERS: 3 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
12	Syncope	FAERS: 3 Canada Vigilance: 2	11867497	CTD SIDER Canada Vigilance US FAERS
13	Vomiting	FAERS: 3 Canada Vigilance: 3	View details 772175 3234463 6488683 6669217 7243095 8959084	CTD SIDER Canada Vigilance US FAERS
14	Acromegaly	FAERS: 2	View details 63831 79115 335755 3226523 7293648	CTD SIDER US FAERS
15	Anxiety	FAERS: 2 Canada Vigilance: 2		Canada Vigilance SIDER US FAERS
16	Blood glucose increased	FAERS: 2		US FAERS
17	Blood prolactin increased	FAERS: 2 Canada Vigilance: 2		Canada Vigilance OFFSIDES US FAERS
18	Cataplexy	FAERS: 2		US FAERS
19	Cerebral artery stenosis	FAERS: 2		OFFSIDES US FAERS
20	Completed Suicide	FAERS: 2		US FAERS
21	Cyanosis	FAERS: 2		US FAERS
22	Depressed Level of Consciousness	FAERS: 2		OFFSIDES US FAERS
23	Drug resistance	FAERS: 2		US FAERS
24	Dysarthria	FAERS: 2		US FAERS
25	Mitral valve sclerosis	FAERS: 2		US FAERS
26	Palpitations	FAERS: 2		US FAERS
27	Posterior reversible encephalopathy syndrome	FAERS: 2		US FAERS
28	Skin irritation	FAERS: 2		US FAERS
29	Tremor	FAERS: 2 Canada Vigilance: 1	319421 989885 6621715	CTD Canada Vigilance US FAERS
30	Tricuspid valve sclerosis	FAERS: 2		US FAERS
31	Visual Impairment	FAERS: 2		SIDER US FAERS
32	treatment failure	FAERS: 2		US FAERS
33	Adverse event	FAERS: 1		US FAERS
34	Agitation	FAERS: 1 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
35	Alanine Aminotransferase Increased	FAERS: 1		OFFSIDES US FAERS
36	Aspartate Aminotransferase Increased	FAERS: 1		US FAERS
37	Atrial Fibrillation	FAERS: 1	11867497	CTD US FAERS
38	Bedridden	FAERS: 1		US FAERS
39	Blindness	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
40	Blood chloride decreased	FAERS: 1		US FAERS
41	Blood sodium decreased	FAERS: 1		US FAERS
42	Bone erosion	FAERS: 1		US FAERS
43	Brain stem syndrome	FAERS: 1		US FAERS
44	Breast hyperplasia	FAERS: 1		US FAERS
45	Brief psychotic disorder, with postpartum onset	FAERS: 1		US FAERS
46	Bromoderma	FAERS: 1		US FAERS
47	Central nervous system lesion	FAERS: 1		OFFSIDES US FAERS
48	Cerebrovascular accident	FAERS: 1		SIDER US FAERS
49	Coronary Artery Disease	FAERS: 1		US FAERS
50	Dizziness	FAERS: 1 Canada Vigilance: 16	View details 3234463 3503918 6454713 6507109 7033847 7243095 8959084	CTD OFFSIDES SIDER Canada Vigilance US FAERS
51	Drug ineffective for unapproved indication	FAERS: 1		US FAERS
52	Ejection Fraction Decreased	FAERS: 1		OFFSIDES US FAERS
53	Emotional disorder	FAERS: 1		US FAERS
54	Erectile dysfunction	FAERS: 1	90217 3115453	CTD US FAERS
55	Genetic Polymorphism	FAERS: 1		US FAERS
56	Heart sounds abnormal	FAERS: 1		OFFSIDES US FAERS
57	Hemiparesis	FAERS: 1		US FAERS
58	Hypersensitivity	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
59	Intentional self-injury	FAERS: 1		US FAERS
60	Left atrial dilatation	FAERS: 1		US FAERS
61	Leukopenia	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
62	Macroglossia	FAERS: 1		US FAERS
63	Macrognathia	FAERS: 1		US FAERS
64	Malaise	FAERS: 1		US FAERS
65	Malnutrition	FAERS: 1		US FAERS
66	Musculoskeletal stiffness	FAERS: 1		US FAERS
67	Myocardial Infarction	FAERS: 1	View details 1395192 2636638 3740157 7839382 8417637 8608461 9024910 9521411 9805577 10099047	CTD SIDER US FAERS
68	Nervousness	FAERS: 1		SIDER US FAERS
69	Neurological decompensation	FAERS: 1		US FAERS
70	Night sweats	FAERS: 1		US FAERS
71	Obsessive-Compulsive Disorder	FAERS: 1		US FAERS
72	PO2 decreased	FAERS: 1		OFFSIDES US FAERS
73	Pericardial effusion	FAERS: 1		OFFSIDES SIDER US FAERS
74	Product use issue	FAERS: 1		US FAERS
75	Quadriplegia	FAERS: 1		US FAERS
76	Rales	FAERS: 1		US FAERS
77	Respiratory Failure	FAERS: 1		US FAERS
78	Respiratory distress	FAERS: 1		US FAERS
79	Restlessness	FAERS: 1		US FAERS
80	Schizophrenia	FAERS: 1	3717443 7200978 8120934	CTD US FAERS
81	Sepsis	FAERS: 1		US FAERS
82	Skin necrosis	FAERS: 1		US FAERS
83	Status Epilepticus	FAERS: 1		SIDER US FAERS
84	Stupor	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
85	Therapy non-responder	FAERS: 1		US FAERS
86	Thrombocytopenia	FAERS: 1		US FAERS
87	Trisomy 21	FAERS: 1		US FAERS
88	Ulcer	FAERS: 1		US FAERS
89	Ventricular hypokinesia	FAERS: 1		OFFSIDES US FAERS
90	Abasia			OFFSIDES
91	Abdominal Cramps			SIDER
92	Abdominal Pain	Canada Vigilance: 1		Canada Vigilance SIDER
93	Abdominal discomfort			SIDER
94	Abdominal rigidity			OFFSIDES
95	Abdominal tenderness			OFFSIDES
96	Abnormal vision			OFFSIDES
97	Abuse			OFFSIDES
98	Activities of daily living impaired			OFFSIDES
99	Acute Coronary Syndrome			SIDER
100	Adenoma		3498743 6717737 8914150	CTD OFFSIDES
101	Adrenal Gland Diseases		12742521	CTD
102	Agraphia			OFFSIDES
103	Akinesia			OFFSIDES
104	Akinetic Mutism		7635387 17895616	CTD
105	Alcoholic Intoxication			OFFSIDES
106	Alopecia			SIDER
107	Amblyopia			SIDER
108	Amenorrhea		View details 85202 86031 86795 1359137 6790306 7196160 7242593 7293665 9617019 15467977	CTD
109	Amnesia	Canada Vigilance: 1		Canada Vigilance OFFSIDES
110	Amphetamines			OFFSIDES
111	Amyotrophic Lateral Sclerosis		21867702	CTD
112	Anorexia			SIDER
113	Anoxic Encephalopathy			OFFSIDES
114	Aortic Valve Insufficiency		18989898	CTD
115	Apallic syndrome			OFFSIDES
116	Apathy			OFFSIDES
117	Aphagia			OFFSIDES
118	Application site excoriation			OFFSIDES
119	Arterial Injury			OFFSIDES
120	Arthralgia	Canada Vigilance: 1		Canada Vigilance
121	Aspiration Pneumonia			OFFSIDES
122	Asthenia	Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER
123	Ataxia			SIDER
124	Aura			OFFSIDES
125	Autoimmune thyroiditis			OFFSIDES
126	Automatism			OFFSIDES
127	Basal Ganglia Diseases		15303389	CTD
128	Biliary dilatation			OFFSIDES
129	Biopsy stomach abnormal			OFFSIDES
130	Biopsy			OFFSIDES
131	Bipolar Disorder		View details 1743505 3625697 3690486 7196160 16446616	CTD
132	Blepharospasm			SIDER
133	Blindness, Cortical		2808744	CTD
134	Blood 1,25-dihydroxycholecalciferol decreased			OFFSIDES
135	Blood cholesterol			OFFSIDES
136	Blood creatine increased			OFFSIDES
137	Blood creatine phosphokinase increased			OFFSIDES
138	Blood growth hormone			OFFSIDES
139	Blood lactate dehydrogenase increased			OFFSIDES
140	Blood thyroid stimulating hormone			OFFSIDES
141	Blood thyroid stimulating hormone increased			OFFSIDES
142	Blood urea increased			OFFSIDES
143	Blood uric acid			OFFSIDES
144	Blurred vision			OFFSIDES
145	Bradycardia		2161850 8976978 11393583	CTD OFFSIDES SIDER
146	Brain Edema		10099047	CTD
147	Brain Injuries		15684763	CTD
148	Brain natriuretic peptide increased			OFFSIDES
149	Breast Diseases		10826333	CTD
150	Breast Feeding			OFFSIDES
151	Breech Presentation			OFFSIDES
152	Bronchitis	Canada Vigilance: 1		Canada Vigilance
153	Bulbar palsy			OFFSIDES
154	Burning sensation			SIDER
155	CNS toxicity			SIDER
156	Cardiac Hypertrophy			OFFSIDES
157	Cardiac discomfort			OFFSIDES
158	Cardiomyopathy, Dilated		15173554	CTD
159	Cardiovascular Diseases		7666753	CTD
160	Carotid Artery Thrombosis		2209050	CTD
161	Carotid artery occlusion			OFFSIDES
162	Catalepsy		View details 2153885 3250915 3283778 9416775 10591873 10683491	CTD
163	Cataract			OFFSIDES
164	Catatonia		3938209	CTD OFFSIDES
165	Cerebral Arterial Diseases		9296138 15602366	CTD
166	Cerebral Hemorrhage		8649587 8766098	CTD
167	Cerebral Infarction		8691994	CTD
168	Cerebral atrophy			OFFSIDES
169	Cerebrospinal Fluid Otorrhea		1407345 8085783	CTD
170	Cerebrospinal Fluid Rhinorrhea		View details 1407345 2814786 6537833 7112390 8059328 8085783 10914763	CTD SIDER
171	Cerebrovascular Disorders		7839382 8976978 12738020	CTD
172	Chemical and Drug Induced Liver Injury		1357362	CTD
173	Chills	Canada Vigilance: 1		Canada Vigilance
174	Choking sensation			OFFSIDES
175	Cold feet			SIDER
176	Cold sweat			OFFSIDES
177	Concomitant disease aggravated			OFFSIDES
178	Confabulation			OFFSIDES
179	Confusion		29497	CTD
180	Conjunctival abrasion			OFFSIDES
181	Constipation	Canada Vigilance: 2	8379567	CTD SIDER Canada Vigilance
182	Coronary Thrombosis		9760093	CTD
183	Cramps of lower extremities			SIDER
184	Craniectomy			OFFSIDES
185	Creatinine renal clearance decreased			OFFSIDES
186	Crying			OFFSIDES
187	Cushing Syndrome		1332855	CTD
188	Dark circles under eyes			OFFSIDES
189	Deep Brain Stimulation			OFFSIDES
190	Depressive disorder		6454713 10815846	CTD
191	Dermatitis			SIDER
192	Diabetes Insipidus			OFFSIDES
193	Diabetes Mellitus			SIDER
194	Diabetic			SIDER
195	Diplopia	Canada Vigilance: 1		Canada Vigilance SIDER
196	Disorders of Excessive Somnolence		10776750	CTD
197	Disorientation	Canada Vigilance: 2		Canada Vigilance
198	Disseminated Intravascular Coagulation			OFFSIDES SIDER
199	Disturbance in sexual arousal			SIDER
200	Drowsiness			SIDER
201	Drug Eruptions		2523364 6213882	CTD
202	Drug dispensing error			OFFSIDES
203	Drug dose omission			OFFSIDES
204	Drug exposure during pregnancy			OFFSIDES
205	Drug exposure via breast milk			OFFSIDES
206	Drug toxicity			OFFSIDES
207	Drug withdrawal headache			OFFSIDES
208	Dysgeusia			SIDER
209	Dyskinesia, Drug-Induced		View details 333856 386307 1414476 1681090 6488198 8749992 11956968	CTD
210	Dyspepsia	Canada Vigilance: 1		Canada Vigilance SIDER
211	Dysphonia			OFFSIDES
212	Dyspnoea exacerbated			OFFSIDES
213	Dystonia		2903183 7651452 8232949	CTD OFFSIDES
214	Dysuria			OFFSIDES
215	Ear and labyrinth disorders			SIDER
216	Electrocardiogram ST-T change			OFFSIDES
217	Empty Sella Syndrome		4072572	CTD OFFSIDES
218	Encephalocele			OFFSIDES
219	Epigastric pain			SIDER
220	Erythromelalgia	Canada Vigilance: 1	6213882	CTD SIDER Canada Vigilance
221	Euphoric mood	Canada Vigilance: 1		Canada Vigilance
222	Excessive daytime sleepiness			SIDER
223	Eye pain	Canada Vigilance: 1		Canada Vigilance OFFSIDES
224	Eyelid Diseases		3503918	CTD
225	Fallopian tube perforation			OFFSIDES
226	Fatigue	Canada Vigilance: 1		Canada Vigilance SIDER
227	Feeling abnormal			OFFSIDES SIDER
228	Feeling of body temperature change			OFFSIDES
229	Fever		8379567 8976978	CTD
230	Fibrosis		12390688 24448315	CTD SIDER
231	Flushing	Canada Vigilance: 1		Canada Vigilance
232	Foreign body trauma			OFFSIDES
233	Gait Disorders, Neurologic		989885 21867702	CTD
234	Galactorrhea		View details 3625697 3690486 7196160 7242593 9617019 14750048 15467977	CTD OFFSIDES
235	Gastrointestinal Diseases		15050800	CTD
236	Gastrointestinal Pain			SIDER
237	Gastrointestinal infection			OFFSIDES
238	Gastrointestinal ulcer			SIDER
239	Gestational Diabetes			OFFSIDES
240	Glasgow coma scale			OFFSIDES
241	Glossoptosis			OFFSIDES
242	Grip strength			OFFSIDES
243	Growth Hormone-Secreting Pituitary Adenoma		3226523 4020451	CTD
244	Gynecomastia		3079888	CTD
245	Hallucinations		View details 386307 772175 3671965 7242593 8214188 10399867 11956968	CTD
246	Hearing Loss, Bilateral		6715973	CTD
247	Heart Diseases		1923236	CTD
248	Heart failure		18926768	CTD
249	Hemianopsia		6790306	CTD
250	Hemiplegia			OFFSIDES
251	Hemorrhage		8914150	CTD
252	Hemothorax			OFFSIDES
253	Hepatic Encephalopathy		6715973	CTD
254	Hernia	Canada Vigilance: 1	11012580	CTD Canada Vigilance
255	Hydronephrosis		2874455	CTD
256	Hyperprolactinemia		View details 1359137 1656408 1681002 3117594 3745407 4047382 6488683 7293665 8959084 9334596 10819748 11194712 12106810 14750048 16209236 18480682 19968833 24187407 29551354	CTD
257	Hypersplenism			OFFSIDES
258	Hyperthyroidism		8691994	CTD
259	Hyperventilation	Canada Vigilance: 1		Canada Vigilance
260	Hypogonadism		3079888 11194712	CTD
261	Hypokinesia		989885 9416775	CTD
262	Hypomania	Canada Vigilance: 1		Canada Vigilance
263	Hypophysectomy			OFFSIDES
264	Hypopituitarism	Canada Vigilance: 1	8191163 15377706	CTD Canada Vigilance
265	Hypotension, Orthostatic		View details 79115 460538 549762 989885 1360112 2096108 3234463 6206310 6488683 8959084	CTD
266	Hypotension		View details 63831 90217 2161850 3304729 3503918 7301555 7372479 9777039 9917201 10626749 10721819 12753422 16916433	CTD SIDER
267	Hypotensive			SIDER
268	Hypoxia			OFFSIDES
269	Incoherent			OFFSIDES
270	Incontinence			OFFSIDES
271	Infantile apnoeic attack			OFFSIDES
272	Infection			SIDER
273	Inflammation		24448315	CTD
274	Influenza			SIDER
275	Injection site pruritus			OFFSIDES
276	Intestinal infarction			OFFSIDES
277	Intubation			OFFSIDES
278	Jugular vein distension			OFFSIDES
279	Keratitis sicca			OFFSIDES
280	Laparotomy			OFFSIDES
281	Lassitude			SIDER
282	Lethargy		8959084	CTD OFFSIDES SIDER
283	Lightheadedness			SIDER
284	Liver neoplasms		16271222	CTD
285	Lymphocyte stimulation test			OFFSIDES
286	Malignant syndrome NOS			SIDER
287	Mediastinal mass			OFFSIDES
288	Medical diet			OFFSIDES
289	Meningitis		8059328	CTD
290	Meningorrhagia			OFFSIDES
291	Menstruation Disturbances		3717443	CTD
292	Mental disorders		989885 7242593	CTD
293	Microlithiasis			OFFSIDES
294	Miliaria	Canada Vigilance: 1		Canada Vigilance
295	Monocyte percentage decreased			OFFSIDES
296	Movement Disorders		772175 10967655	CTD
297	Multiple Pregnancy			OFFSIDES
298	Murder			OFFSIDES
299	Muscle Rigidity		989885 8379567	CTD
300	Myeloblast count increased			OFFSIDES
301	Myelocyte count decreased			OFFSIDES
302	Myoclonus		77316 478382 3574698	CTD
303	Myotonia			OFFSIDES
304	Nail Infection			OFFSIDES
305	Nasopharyngitis			SIDER
306	Neuroleptic Malignant Syndrome		View details 2925603 6134848 6614876 7999444 8101521 10675082 12397878 15830831 17119106 17214072	CTD OFFSIDES SIDER
307	Neurological examination abnormal	Canada Vigilance: 1		Canada Vigilance
308	Numbness			SIDER
309	Ocular discomfort			SIDER
310	Ocular icterus			OFFSIDES
311	Ocular vascular disorder			OFFSIDES
312	Oculogyric crisis	Canada Vigilance: 1		Canada Vigilance
313	Oligomenorrhea		1359137	CTD
314	Orthopnea			OFFSIDES
315	Osteopetrosis			OFFSIDES
316	Ovarian Hyperstimulation Syndrome		12727942	CTD
317	Pain of skin			OFFSIDES
318	Pain		1673775 16563475	CTD
319	Pallor facial			SIDER
320	Pallor			OFFSIDES SIDER
321	Panic Disorder			OFFSIDES
322	Paranoia	Canada Vigilance: 2		Canada Vigilance SIDER
323	Parkinson Disease		View details 121706 319421 333856 386307 772175 773080 989885 1295627 1809340 2181588 2746281 2864254 3115453 3185626 3990974 6105390 6110850 6151826 6213882 6497767 6682193 7046720 7901395 8552122 9918342 10534217 10776750 11194495 11487183 11956968 12086551 12390688 12614313 15050800 15551331 16258207 18328768 18989898	CTD
324	Parkinsonian Disorders		View details 572493 666607 1567736 1681090 10683491	CTD
325	Peptic Ulcer			SIDER
326	Pericarditis, Constrictive		1809340 10534217 15050800	CTD
327	Pericarditis		19170199	CTD SIDER
328	Personality Disorders		29497	CTD
329	Pharmaceutical product counterfeit			OFFSIDES
330	Pituitary Apoplexy		3226523 4020451 7293648	CTD
331	Pituitary Diseases		6717737	CTD
332	Pituitary Neoplasms		View details 1360112 3498743 3625096 3817228 6573538 15251663 19595700	CTD
333	Pituitary infarction			OFFSIDES
334	Pleurisy	Canada Vigilance: 1	19170199	CTD SIDER Canada Vigilance
335	Pneumocephalus		6669217	CTD
336	Pneumonia	Canada Vigilance: 1		Canada Vigilance
337	Polyhydramnios			OFFSIDES
338	Polyneuropathy			OFFSIDES
339	Polyuria			OFFSIDES
340	Poverty			OFFSIDES
341	Pregnancy Complications, Cardiovascular		18926768	CTD
342	Presbyopia			OFFSIDES
343	Presyncope			SIDER
344	Procedural complication			OFFSIDES
345	Progressive supranuclear palsy			OFFSIDES
346	Prolactinoma		View details 79046 86800 1407345 2814786 2887062 2903183 3226523 3593602 3660204 4070720 4072572 6537833 6669217 6725514 7070622 7168914 7302322 8059328 8120934 8956160 9509075 9617019 10819748 10914763 11012580 12161478 15046398 15173554 15749434 18204364 20063113	CTD OFFSIDES
347	Pruritus	Canada Vigilance: 1		Canada Vigilance
348	Psychoses, Substance-Induced		View details 29497 60643 1743505 2181588 3686155 9267376 10099047 16446616	CTD
349	Psychotic Disorders		1359137 6812691 15467977	CTD
350	Puerperal Disorders		View details 1395192 1874430 1923236 2209050 2808744 3625697 3740157 3840873 7839382 8641870 8649587 8691994 8766098 9024910 9267376 9296138 9805577 10099047 11338413 12738020 15602366 18926768	CTD
351	Pulmonary Edema		2327446	CTD
352	Pulmonary Embolism	Canada Vigilance: 1		Canada Vigilance
353	Pulmonary Fibrosis		19170199	CTD SIDER
354	Pulmonary vasculitis			OFFSIDES
355	Raynaud Disease		561947 3117594 8977979	CTD
356	Rectocele			OFFSIDES
357	Renal Colic			OFFSIDES
358	Respiratory tract congestion			OFFSIDES
359	Retching	Canada Vigilance: 1		Canada Vigilance
360	Retinal Detachment	Canada Vigilance: 1		Canada Vigilance
361	Retinal Vein Occlusion		9380363	CTD
362	Retrocollis			OFFSIDES
363	Retroperitoneal fibrosis		2874455 15050800	CTD SIDER
364	Rhinitis			OFFSIDES SIDER
365	Rhinorrhea			OFFSIDES
366	Risus sardonicus			OFFSIDES
367	Salpingectomy			OFFSIDES
368	Schizoaffective Disorder			OFFSIDES
369	Seizures		View details 1874430 1923236 2808744 8914150 8976978 9666168 10099047 12738020	CTD
370	Septoplasty			OFFSIDES
371	Serotonin Syndrome		3711372	CTD
372	Shock			SIDER
373	Sick Sinus Syndrome			OFFSIDES
374	Sinusitis			SIDER
375	Sleep Bruxism		9294496 15749418	CTD
376	Sleep Initiation and Maintenance Disorders		1964203	CTD
377	Sleep Wake Disorders		2141985	CTD
378	Sluggishness			SIDER
379	Soliloquy			OFFSIDES
380	Stomach Diseases		11292068	CTD
381	Strawberry tongue			OFFSIDES
382	Substance Withdrawal Syndrome		2903183 3981206	CTD
383	Sudden onset of sleep			SIDER
384	Tachycardia, Ventricular		1923236 6501720	CTD
385	Tachycardia	Canada Vigilance: 1	View details 9777039 10721819 11393583 12753422	CTD SIDER Canada Vigilance
386	Tendinitis			OFFSIDES
387	Tension			SIDER
388	Tinnitus			SIDER
389	Trigeminal Neuralgia		3412598	CTD
390	Troponin T			OFFSIDES
391	Ultrasound skull abnormal			OFFSIDES
392	Unresponsive to verbal stimuli			OFFSIDES
393	Ureteral obstruction		2874455	CTD
394	Urinary Incontinence		6139616 6775584	CTD SIDER
395	Urinary Retention		8379567	CTD SIDER
396	Urticaria			SIDER
397	Uterine cervical pain			OFFSIDES
398	Vasculitis			SIDER
399	Vasospasm, Intracranial		1923236	CTD
400	Vasospasm	Canada Vigilance: 1		Canada Vigilance SIDER
401	Ventricular Fibrillation			OFFSIDES
402	Vertigo	Canada Vigilance: 2		Canada Vigilance SIDER
403	Vision Disorders		View details 1360112 3817228 3981206 6717737 8956160 11012580	CTD
404	Visual disturbance			OFFSIDES SIDER
405	Weight decreased	Canada Vigilance: 1		Canada Vigilance
406	Whole blood transfusion			OFFSIDES
407	Wound Complication			OFFSIDES
408	furuncle			OFFSIDES
409	nervous system disorder			SIDER

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