MetaADEDB 2.0 @ LMMD
Remifentanil
(ZTVQQQVZCWLTDF-UHFFFAOYSA-N)
Structure
SMILES
COC(=O)C1(CCN(CC1)CCC(=O)OC)N(c1ccccc1)C(=O)CC
Type(s)
Approved
ATC code(s)
N01AH06
Molecular Formula:
C20H28N2O5
Molecular Weight:
376.447
Log P:
1.9382
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
0
TPSA:
76.15
CAS Number(s):
132875-61-7
Synonym(s)
1.
Remifentanil
2.
3-(4-Methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic Acid Methyl Ester
3.
GI 87084B
4.
GI-87084B
5.
GI87084B
6.
Remifentanil Hydrochloride
7.
Remifentanil Monohydrochloride
8.
Ultiva
External Link(s)
MeSHD000077208
PubChem Compound60815
BindingDB50012491
ChEBI8802
CHEMBLCHEMBL1005
DrugBankDB00899
DrugCentral2363
IUPHAR/BPS Guide to PHARMACOLOGY7292
KEGGcpd:C08021
dr:D08473
Therapeutic Target DatabaseD0T5OX
ZINC538283
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Cardiac ArrestFAERS: 7SIDER
US FAERS
2BradycardiaFAERS: 6
Canada Vigilance: 1

View details

9357922
10793617
10995163
17587605
17697311
18794167
18942252
20077594
20394247
 		CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
3Respiratory DepressionFAERS: 6SIDER
US FAERS
4Accidental overdoseFAERS: 3US FAERS
5AcidosisFAERS: 2OFFSIDES
US FAERS
6Blood pressure fluctuationFAERS: 2OFFSIDES
US FAERS
7Chest PainFAERS: 2US FAERS
8Depressed Level of ConsciousnessFAERS: 2OFFSIDES
US FAERS
9Drug administration errorFAERS: 2US FAERS
10Drug ineffectiveFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
11Infusion Site ExtravasationFAERS: 2US FAERS
12Maternal exposure during deliveryFAERS: 2US FAERS
13SplenomegalyFAERS: 2US FAERS
14TachycardiaFAERS: 2SIDER
US FAERS
15Accidental exposure to productFAERS: 1US FAERS
16Accidental exposureFAERS: 1US FAERS
17Cold sweatFAERS: 1US FAERS
18Completed SuicideFAERS: 1US FAERS
19CyanosisFAERS: 1US FAERS
20Device FailureFAERS: 1US FAERS
21Device infusion issueFAERS: 1US FAERS
22Drug ToleranceFAERS: 1US FAERS
23Drug exposure during pregnancyFAERS: 1OFFSIDES
US FAERS
24Eye irritationFAERS: 1US FAERS
25HypotensionFAERS: 1

View details

9357922
16077295
17285425
17587605
18502357
18942252
19178808
20077594
 		CTD
SIDER
US FAERS
26Incorrect dose administeredFAERS: 1US FAERS
27Maternal exposure during pregnancyFAERS: 1US FAERS
28Medication ErrorFAERS: 1US FAERS
29Muscle RigidityFAERS: 19286888
19685109		CTD
SIDER
US FAERS
30Neonatal disorderFAERS: 1US FAERS
31Neonatal respiratory depressionFAERS: 1US FAERS
32OverdoseFAERS: 1US FAERS
33PallorFAERS: 1OFFSIDES
US FAERS
34Seizure like phenomenaFAERS: 1US FAERS
35Visual ImpairmentFAERS: 1SIDER
US FAERS
36Abdominal discomfortSIDER
37Abdominal wound dehiscenceOFFSIDES
38AcheSIDER
39Activated partial thromboplastin time shortenedOFFSIDES
40Acute otitis mediaOFFSIDES
41AgitationSIDER
42Air EmbolismOFFSIDES
43Altered state of consciousnessOFFSIDES
44AmnesiaSIDER
45Anaphylactic shockSIDER
46AnisocoriaOFFSIDES
47Anticholinergic SyndromeOFFSIDES
48Anxiety postoperativeOFFSIDES
49AnxietySIDER
50Apallic syndromeOFFSIDES
51Aphthous StomatitisOFFSIDES
52Apnea18761243
20461001
20865877		CTD
OFFSIDES
53AtelectasisSIDER
54AthetosisOFFSIDES
55Atrial FibrillationSIDER
56Atrial FlutterSIDER
57Atrial tachycardiaOFFSIDES
58Atrioventricular BlockSIDER
59Autologous bone marrow transplantation therapyOFFSIDES
60AutomatismOFFSIDES
61BasophiliaOFFSIDES
62Bilirubin conjugated increasedOFFSIDES
63Blood creatine phosphokinase increasedSIDER
64Blood creatinine increasedOFFSIDES
65Blood glucose fluctuationOFFSIDES
66Blood in stoolSIDER
67Blood pH increasedOFFSIDES
68Blood phosphorus increasedOFFSIDES
69Blood pressure immeasurableOFFSIDES
70Bone lesionOFFSIDES
71Brain DeathOFFSIDES
72Brain Injuries11973195CTD
73BronchitisSIDER
74BronchospasmSIDER
75C-reactive protein abnormalOFFSIDES
76CardiotoxicityOFFSIDES
77Cataract operationOFFSIDES
78Cerebral InfarctionSIDER
79Cerebral disorderOFFSIDES
80Cerebral hypoperfusionOFFSIDES
81Cerebral perfusion pressure decreasedOFFSIDES
82ChillsSIDER
83CholangiolitisOFFSIDES
84Colonic StenosisOFFSIDES
85ConstipationSIDER
86Creatine Phosphokinase IncreasedSIDER
87CystOFFSIDES
88DemyelinationOFFSIDES
89Depressed moodOFFSIDES
90DermatitisSIDER
91DisorientationSIDER
92DiverticulitisOFFSIDES
93DiverticulumOFFSIDES
94DizzinessSIDER
95Drug toxicityOFFSIDES
96DyspepsiaSIDER
97DysuriaSIDER
98Electrocardiogram changeSIDER
99Electrolyte imbalanceSIDER
100Endodontic procedureOFFSIDES
101Endoscopy abnormalOFFSIDES
102Eosinophilic myocarditisOFFSIDES
103ErythemaSIDER
104Familial risk factorOFFSIDES
105Feeling abnormalSIDER
106FibrinolysisOFFSIDES
107FlushingSIDER
108Glasgow coma scaleOFFSIDES
109GlomerulonephritisOFFSIDES
110GlossectomyOFFSIDES
111HeadacheSIDER
112HeartburnSIDER
113Hepatic congestionOFFSIDES
114Hepatitis B VirusOFFSIDES
115Histamine level increasedOFFSIDES
116Hyperalgesia

View details

12933407
14581115
15983467
16285546
16508403
19955894
20042082
20077594
20876698
21390173
 		CTD
117HypercapniaOFFSIDES
118HyperparathyroidismOFFSIDES
119HyperreflexiaOFFSIDES
120HypersensitivitySIDER
121Hypoglossal nerve paresisOFFSIDES
122HypophagiaOFFSIDES
123HypotensiveSIDER
124HypoxiaOFFSIDES
SIDER
125IleusSIDER
126Impaired gastric emptyingOFFSIDES
127Infusion site reactionSIDER
128Intervertebral Disc DegenerationOFFSIDES
129IntubationOFFSIDES
130Kaolin cephalin clotting time prolongedOFFSIDES
131Kidney Diseases18502357CTD
132LaryngospasmSIDER
133LethargyOFFSIDES
134LeukocytosisSIDER
135LeukoencephalopathyOFFSIDES
136Locked-In SyndromeOFFSIDES
137Low Cardiac Output SyndromeOFFSIDES
138LymphopeniaSIDER
139Mechanical ventilationOFFSIDES
140Metabolic acidosisOFFSIDES
141MonoparesisOFFSIDES
142Musculoskeletal chest painSIDER
143Musculoskeletal discomfortOFFSIDES
144Musculoskeletal stiffnessSIDER
145Myasthenia GravisOFFSIDES
146Myoclonus16563323
18230263		CTD
147MyoglobinaemiaOFFSIDES
148NasopharyngitisSIDER
149Nausea11159231CTD
SIDER
150Neck Pain17197214CTD
151NystagmusSIDER
152OliguriaOFFSIDES
SIDER
153Opioid-Related Disorders26777139CTD
154PCO2 decreasedOFFSIDES
155PO2 decreasedOFFSIDES
156Pain, Postoperative

View details

11573581
15983467
16285546
18289446
20042082
20876698
21390173
 		CTD
157Pain

View details

10220941
10713867
11133605
14581115
15128647
15590252
16508403
17159759
17294999
17513655
17563129
18006530
18044287
18081358
19955894
20589177
 		CTD
SIDER
158PericarditisSIDER
159PharyngitisSIDER
160PiloerectionOFFSIDES
161PneumoniaSIDER
162PneumothoraxSIDER
163PolyuriaOFFSIDES
164Post procedural complicationOFFSIDES
SIDER
165Post procedural infectionSIDER
166Post procedural painOFFSIDES
167Postoperative Complications15352962CTD
168Postoperative Nausea and Vomiting10220941
10713867		CTD
169Postoperative feverOFFSIDES
170Postoperative hypertensionSIDER
171Postoperative infectionSIDER
172Postoperative shiveringSIDER
173Potentiating drug interactionOFFSIDES
174Procedural hypertensionSIDER
175Procedural hypotensionOFFSIDES
176Procedural vomitingOFFSIDES
177Product quality issueOFFSIDES
178Propofol Infusion SyndromeOFFSIDES
179PruritusSIDER
180Pseudocholinesterase deficiencyOFFSIDES
181Pulmonary HypertensionOFFSIDES
182Pulmonary congestionSIDER
183Pulmonary function test decreasedSIDER
184RalesSIDER
185Renal tubular necrosisOFFSIDES
186Respiratory Insufficiency20461001CTD
187Respiratory depth decreasedOFFSIDES
188Respiratory distressSIDER
189Respiratory tract congestionSIDER
190RhabdomyolysisOFFSIDES
191RhonchiSIDER
192Risus sardonicusOFFSIDES
193Seizures10792882CTD
194ShiveringSIDER
195ShockSIDER
196Sinoatrial BlockOFFSIDES
197Skin test negativeOFFSIDES
198Skin test positiveOFFSIDES
199Sleep Wake Disorders17377082CTD
200SomnolenceSIDER
201Spinal column stenosisOFFSIDES
202Splenic InfarctionOFFSIDES
203SpondylolisthesisOFFSIDES
204Sputum culture positiveOFFSIDES
205StaringOFFSIDES
206Stem cell transplantOFFSIDES
207Stenotrophomonas infectionOFFSIDES
208StridorSIDER
209SubileusOFFSIDES
210Substance Withdrawal Syndrome16285546
21390173
26777139		CTD
211SweatingSIDER
212SyncopeSIDER
213Synovial CystOFFSIDES
214TendinitisOFFSIDES
215ThrombocytopeniaSIDER
216TremorSIDER
217Troponin increasedOFFSIDES
218Tryptase increasedOFFSIDES
219Upper airway obstructionOFFSIDES
220Urinary IncontinenceSIDER
221Urinary RetentionSIDER
222Urine ketone body presentOFFSIDES
223UrticariaSIDER
224Ventricular FibrillationSIDER
225Ventricular arrhythmiaSIDER
226Ventricular hypokinesiaOFFSIDES
227Visual disturbanceSIDER
228Vomiting11159231CTD
SIDER
229Wound infection bacterialOFFSIDES
230nervous system disorderSIDER
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