MetaADEDB 2.0 @ LMMD
Lidoderm
(NNJVILVZKWQKPM-UHFFFAOYSA-N)
Structure
SMILES
CCN(CC(=O)Nc1c(C)cccc1C)CC
Type(s)
Approved; Vet_approved
ATC code(s)
C01BB01; C05AD01; D04AB01; N01BB02; N01BB52; R02AD02; S01HA07; S02DA01
Molecular Formula:
C14H22N2O
Molecular Weight:
234.337
Log P:
2.6567
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
32.34
CAS Number(s):
73-78-9; 137-58-6; 91484-71-8
Synonym(s)
1.
Lidoderm
External Link(s)
MeSHC511998
PubChem Compound3676
BindingDB50017662
ChEBI6456
CHEMBLCHEMBL79
DrugBankDB00281
DrugCentral1579
IUPHAR/BPS Guide to PHARMACOLOGY2623
KEGGcpd:C07073
dr:D00358
Therapeutic Target DatabaseD0X4RN
ZINC20237
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 343
Canada Vigilance: 16
Canada Vigilance
US FAERS
2Product adhesion issueFAERS: 255US FAERS
3Product quality issueFAERS: 236
Canada Vigilance: 3
Canada Vigilance
US FAERS
4Toxicity to various agentsFAERS: 98
Canada Vigilance: 4
Canada Vigilance
US FAERS
5Drug ineffective for unapproved indicationFAERS: 95US FAERS
6OverdoseFAERS: 80
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
7Anaphylactic shockFAERS: 71SIDER
US FAERS
8Cardiac ArrestFAERS: 67
Canada Vigilance: 6
Canada Vigilance
SIDER
US FAERS
9DizzinessFAERS: 66
Canada Vigilance: 3

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CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
10PainFAERS: 58
Canada Vigilance: 2

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CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
11NauseaFAERS: 54
Canada Vigilance: 9

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CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
12HypotensionFAERS: 51
Canada Vigilance: 1

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CTD
SIDER
Canada Vigilance
US FAERS
13Medication ErrorFAERS: 42
Canada Vigilance: 1
Canada Vigilance
US FAERS
14MalaiseFAERS: 39
Canada Vigilance: 4
Canada Vigilance
US FAERS
15ShockFAERS: 39SIDER
US FAERS
16BradycardiaFAERS: 36
Canada Vigilance: 2

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CTD
SIDER
Canada Vigilance
US FAERS
17Drug toxicityFAERS: 36OFFSIDES
US FAERS
18Incorrect route of drug administrationFAERS: 35US FAERS
19No adverse eventFAERS: 33US FAERS
20Product use in unapproved indicationFAERS: 33US FAERS
21SomnolenceFAERS: 32
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
22PallorFAERS: 30US FAERS
23Application site painFAERS: 29OFFSIDES
US FAERS
24HypersensitivityFAERS: 29
Canada Vigilance: 1
21252830CTD
SIDER
Canada Vigilance
US FAERS
25Application site rashFAERS: 28US FAERS
26Expired product administeredFAERS: 28US FAERS
27Feeling abnormalFAERS: 28SIDER
US FAERS
28Depressed Level of ConsciousnessFAERS: 26OFFSIDES
SIDER
US FAERS
29TremorFAERS: 26
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
30TachycardiaFAERS: 25

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CTD
US FAERS
31Application site erythemaFAERS: 24US FAERS
32VomitingFAERS: 24
Canada Vigilance: 4

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CTD
SIDER
Canada Vigilance
US FAERS
33Drug administration errorFAERS: 23US FAERS
34Respiratory arrestFAERS: 23
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
35SyncopeFAERS: 23
Canada Vigilance: 1
4635436CTD
Canada Vigilance
US FAERS
36UrticariaFAERS: 23
Canada Vigilance: 2
11792017CTD
SIDER
Canada Vigilance
US FAERS
37Wrong technique in product usage processFAERS: 22US FAERS
38HeadacheFAERS: 21
Canada Vigilance: 1

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CTD
SIDER
Canada Vigilance
US FAERS
39PalpitationsFAERS: 20
Canada Vigilance: 1
Canada Vigilance
US FAERS
40Product substitution issueFAERS: 20US FAERS
41PruritusFAERS: 20US FAERS
42AgitationFAERS: 19SIDER
US FAERS
43CyanosisFAERS: 19
Canada Vigilance: 2
17612444
18406071
CTD
Canada Vigilance
US FAERS
44ErythemaFAERS: 18
Canada Vigilance: 1
1371395
18450903
CTD
SIDER
Canada Vigilance
US FAERS
45Accidental overdoseFAERS: 17
Canada Vigilance: 1
Canada Vigilance
US FAERS
46Incorrect drug administration durationFAERS: 17OFFSIDES
US FAERS
47Pharmaceutical product complaintFAERS: 17US FAERS
48Chest PainFAERS: 1517612444CTD
OFFSIDES
SIDER
US FAERS
49Intentional product misuseFAERS: 15US FAERS
50RestlessnessFAERS: 15US FAERS
51AstheniaFAERS: 14OFFSIDES
SIDER
US FAERS
52DysarthriaFAERS: 145746297CTD
SIDER
US FAERS
53FatigueFAERS: 14
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
54Product physical issueFAERS: 14US FAERS
55Status EpilepticusFAERS: 14

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CTD
US FAERS
56Unresponsive to stimuliFAERS: 14OFFSIDES
US FAERS
57Incorrect dose administeredFAERS: 13OFFSIDES
US FAERS
58MydriasisFAERS: 1318406071CTD
US FAERS
59Post procedural complicationFAERS: 13OFFSIDES
US FAERS
60Procedural complicationFAERS: 13OFFSIDES
US FAERS
61Respiratory FailureFAERS: 13
Canada Vigilance: 1
Canada Vigilance
US FAERS
62Accidental exposure to productFAERS: 12US FAERS
63AnxietyFAERS: 12
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
64Application site discomfortFAERS: 12US FAERS
65Application site irritationFAERS: 12
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
66Chest discomfortFAERS: 12US FAERS
67DeliriumFAERS: 123812782
4188133
CTD
US FAERS
68DiplopiaFAERS: 12

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CTD
SIDER
US FAERS
69Drug effect incompleteFAERS: 12US FAERS
70HypoxiaFAERS: 129803439CTD
US FAERS
71Wrong drug administeredFAERS: 12US FAERS
72AngioedemaFAERS: 113578739
17537275
CTD
SIDER
US FAERS
73Burning sensationFAERS: 11SIDER
US FAERS
74FlushingFAERS: 11SIDER
US FAERS
75Skin necrosisFAERS: 11US FAERS
76Application site pruritusFAERS: 10US FAERS
77ArthralgiaFAERS: 10US FAERS
78CardiotoxicityFAERS: 10US FAERS
79Cerebrovascular accidentFAERS: 10US FAERS
80Cold sweatFAERS: 10
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
US FAERS
81Ventricular FibrillationFAERS: 10

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CTD
OFFSIDES
SIDER
US FAERS
82Visual ImpairmentFAERS: 10SIDER
US FAERS
83nervous system disorderFAERS: 10SIDER
US FAERS
84AphasiaFAERS: 9
Canada Vigilance: 1
Canada Vigilance
US FAERS
85Metabolic acidosisFAERS: 9OFFSIDES
US FAERS
86Retinal Artery OcclusionFAERS: 9US FAERS
87Brain DeathFAERS: 8OFFSIDES
US FAERS
88Drug abuseFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
89Feeling ColdFAERS: 8US FAERS
90Long QT SyndromeFAERS: 8

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CTD
US FAERS
91Neck PainFAERS: 812672838
16102894
CTD
US FAERS
92Product use issueFAERS: 8
Canada Vigilance: 2
Canada Vigilance
US FAERS
93Therapeutic response unexpectedFAERS: 8US FAERS
94WheezingFAERS: 8US FAERS
95Accidental exposureFAERS: 7US FAERS
96Altered state of consciousnessFAERS: 7US FAERS
97Application site reactionFAERS: 7SIDER
US FAERS
98Drug label confusionFAERS: 7US FAERS
99Drug prescribing errorFAERS: 7US FAERS
100Drug screen positiveFAERS: 7US FAERS
101DysgeusiaFAERS: 710553842CTD
SIDER
US FAERS
102HemiparesisFAERS: 7US FAERS
103Inappropriate schedule of drug administrationFAERS: 7OFFSIDES
US FAERS
104MyalgiaFAERS: 7US FAERS
105Myocardial InfarctionFAERS: 7

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CTD
US FAERS
106Prescription drug used without a prescriptionFAERS: 7US FAERS
107Respiratory distressFAERS: 7US FAERS
108VertigoFAERS: 7

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CTD
US FAERS
109AbasiaFAERS: 6US FAERS
110ConstipationFAERS: 6US FAERS
111DisorientationFAERS: 6SIDER
US FAERS
112Drug effective for unapproved indicationFAERS: 6US FAERS
113Foreign body traumaFAERS: 6US FAERS
114Hepatic EncephalopathyFAERS: 6US FAERS
115Inadequate analgesiaFAERS: 6US FAERS
116InfectionFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
117Injection site painFAERS: 6US FAERS
118LethargyFAERS: 6
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
119Muscle RigidityFAERS: 6US FAERS
120NystagmusFAERS: 6US FAERS
121Product use complaintFAERS: 6US FAERS
122SyringomyeliaFAERS: 6US FAERS
123Wrong technique in drug usage processFAERS: 6OFFSIDES
US FAERS
124Acute kidney injuryFAERS: 5US FAERS
125Adverse eventFAERS: 5US FAERS
126Application site vesiclesFAERS: 5US FAERS
127Back PainFAERS: 5

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CTD
SIDER
US FAERS
128Blood pressure fluctuationFAERS: 5US FAERS
129ChillsFAERS: 5SIDER
US FAERS
130DiplegiaFAERS: 5US FAERS
131EndophthalmitisFAERS: 5US FAERS
132EpilepsyFAERS: 59768791CTD
OFFSIDES
US FAERS
133Incision site complicationFAERS: 5US FAERS
134Injection site erythemaFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
135Injection site extravasationFAERS: 5US FAERS
136Intentional drug misuseFAERS: 5US FAERS
137Peripheral swellingFAERS: 5US FAERS
138PneumoniaFAERS: 5US FAERS
139Product leakageFAERS: 5US FAERS
140Respiratory DepressionFAERS: 5SIDER
US FAERS
141StrabismusFAERS: 56579181
11641647
CTD
US FAERS
142Sudden deathFAERS: 5OFFSIDES
US FAERS
143Throat irritationFAERS: 5US FAERS
144TinnitusFAERS: 5

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CTD
SIDER
US FAERS
145Acute myocardial infarctionFAERS: 4US FAERS
146Acute respiratory failureFAERS: 4US FAERS
147AgeusiaFAERS: 4US FAERS
148Application site urticariaFAERS: 4US FAERS
149AsthmaFAERS: 4SIDER
US FAERS
150Atrioventricular BlockFAERS: 4

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CTD
SIDER
US FAERS
151BlindnessFAERS: 41815916
12088973
19631139
CTD
US FAERS
152Blood creatinine increasedFAERS: 4OFFSIDES
US FAERS
153Blood pressure immeasurableFAERS: 4US FAERS
154BronchospasmFAERS: 4
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
155Cerebral InfarctionFAERS: 4US FAERS
156Circumstance or information capable of leading to medication errorFAERS: 4US FAERS
157Device breakageFAERS: 4US FAERS
158Drug dispensing errorFAERS: 4US FAERS
159Drug level increasedFAERS: 4
Canada Vigilance: 2
Canada Vigilance
US FAERS
160Inappropriate schedule of product administrationFAERS: 4US FAERS
161Incorrect product administration durationFAERS: 4US FAERS
162Mental status changesFAERS: 4OFFSIDES
US FAERS
163Nerve injuryFAERS: 4SIDER
US FAERS
164PresyncopeFAERS: 4US FAERS
165Product closure removal difficultFAERS: 4US FAERS
166Product formulation issueFAERS: 4US FAERS
167Product packaging issueFAERS: 4US FAERS
168Product packaging quantity issueFAERS: 4US FAERS
169SepsisFAERS: 4
Canada Vigilance: 2
Canada Vigilance
US FAERS
170Slow response to stimuliFAERS: 4US FAERS
171Supraventricular tachycardiaFAERS: 4US FAERS
172Thermal burnFAERS: 4US FAERS
173Abdominal discomfortFAERS: 3US FAERS
174Activities of daily living impairedFAERS: 3US FAERS
175AlopeciaFAERS: 3US FAERS
176AmaurosisFAERS: 3US FAERS
177Apallic syndromeFAERS: 3US FAERS
178ApathyFAERS: 3OFFSIDES
US FAERS
179Application site exfoliationFAERS: 3US FAERS
180Application site inflammationFAERS: 3US FAERS
181Application site lacerationFAERS: 3US FAERS
182Application site warmthFAERS: 3US FAERS
183AtaxiaFAERS: 3

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CTD
US FAERS
184Atrial FibrillationFAERS: 3576484CTD
US FAERS
185Blood glucose increasedFAERS: 3US FAERS
186Blood urea increasedFAERS: 3US FAERS
187Choking sensationFAERS: 3OFFSIDES
US FAERS
188Completed SuicideFAERS: 3OFFSIDES
US FAERS
189DemyelinationFAERS: 3US FAERS
190DependenceFAERS: 3US FAERS
191Device ineffectiveFAERS: 3US FAERS
192DiscomfortFAERS: 3US FAERS
193Drug exposure during pregnancyFAERS: 3US FAERS
194Expired drug administeredFAERS: 3US FAERS
195General physical health deteriorationFAERS: 3
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
196HomicideFAERS: 3US FAERS
197Joint injuryFAERS: 3US FAERS
198Joint swellingFAERS: 3US FAERS
199Limb discomfortFAERS: 3US FAERS
200Maternal exposure during pregnancyFAERS: 3US FAERS
201Muscle tightnessFAERS: 3US FAERS
202NecrosisFAERS: 3

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CTD
US FAERS
203Oropharyngeal discomfortFAERS: 3SIDER
US FAERS
204PneumocephalusFAERS: 3US FAERS
205PoisoningFAERS: 3US FAERS
206Poor quality drug administeredFAERS: 3US FAERS
207Posterior reversible encephalopathy syndromeFAERS: 3US FAERS
208Product container issueFAERS: 3US FAERS
209Product container seal issueFAERS: 3US FAERS
210Product physical consistency issueFAERS: 3US FAERS
211Product storage errorFAERS: 3US FAERS
212Right Ventricular DysfunctionFAERS: 3US FAERS
213Sinus TachycardiaFAERS: 3US FAERS
214Sinus bradycardiaFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
215Skin lesionFAERS: 3US FAERS
216Skin reactionFAERS: 3US FAERS
217Stevens-Johnson SyndromeFAERS: 3US FAERS
218Suicide attemptFAERS: 3US FAERS
219SwellingFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
220Therapeutic product ineffectiveFAERS: 3US FAERS
221Unevaluable eventFAERS: 3US FAERS
222Urinary tract infectionFAERS: 3US FAERS
223Weight decreasedFAERS: 3US FAERS
224treatment failureFAERS: 3US FAERS
225Abdominal PainFAERS: 2OFFSIDES
US FAERS
226Abortion complicatedFAERS: 2US FAERS
227Accidental exposure to product by childFAERS: 2US FAERS
228Acute Coronary SyndromeFAERS: 2US FAERS
229Alanine Aminotransferase IncreasedFAERS: 2OFFSIDES
US FAERS
230AmnesiaFAERS: 2US FAERS
231Anaphylactoid ReactionFAERS: 2SIDER
US FAERS
232AnosmiaFAERS: 2US FAERS
233Application site coldnessFAERS: 2US FAERS
234Application site swellingFAERS: 2US FAERS
235Arteriovenous fistulaFAERS: 2US FAERS
236AsterixisFAERS: 2US FAERS
237AtelectasisFAERS: 2US FAERS
238Brain stem syndromeFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
239Cardiomyopathy acuteFAERS: 2US FAERS
240Corneal OpacityFAERS: 2US FAERS
241CryingFAERS: 2US FAERS
242Descemet's membrane disorderFAERS: 2US FAERS
243Device leakageFAERS: 2US FAERS
244Device physical property issueFAERS: 2US FAERS
245Diabetes MellitusFAERS: 2US FAERS
246DisabilityFAERS: 2US FAERS
247Disease ProgressionFAERS: 2US FAERS
248Drug DependenceFAERS: 2US FAERS
249Drug dose omissionFAERS: 2US FAERS
250Drug effect delayedFAERS: 2US FAERS
251Drug resistanceFAERS: 2US FAERS
252Endotracheal intubation complicationFAERS: 2SIDER
US FAERS
253Exposure via eye contactFAERS: 2US FAERS
254Eye BurnsFAERS: 2US FAERS
255Eye irritationFAERS: 2US FAERS
256Eye painFAERS: 2US FAERS
257Facial paralysisFAERS: 28956858
14689429
CTD
US FAERS
258Gait inabilityFAERS: 2US FAERS
259Gaze palsyFAERS: 2US FAERS
260HepatitisFAERS: 2US FAERS
261Hoigne's syndromeFAERS: 2US FAERS
262HyperreflexiaFAERS: 2US FAERS
263Hypertensive crisisFAERS: 2US FAERS
264Hypoaesthesia facialFAERS: 2US FAERS
265HypokinesiaFAERS: 2US FAERS
266HypoventilationFAERS: 2US FAERS
267Impaired driving abilityFAERS: 2US FAERS
268IncoherentFAERS: 2US FAERS
269Incorrect dose administered by deviceFAERS: 2US FAERS
270InfluenzaFAERS: 2US FAERS
271Infrequent bowel movementsFAERS: 2US FAERS
272Injection Site ReactionFAERS: 2US FAERS
273Intervertebral Disc DegenerationFAERS: 2US FAERS
274LaryngospasmFAERS: 2SIDER
US FAERS
275Limb injuryFAERS: 2US FAERS
276Lip swellingFAERS: 2US FAERS
277Liquid product physical issueFAERS: 2US FAERS
278LymphangitisFAERS: 2OFFSIDES
US FAERS
279Malignant neoplasm progressionFAERS: 2OFFSIDES
US FAERS
280Medical device complicationFAERS: 2US FAERS
281Memory impairmentFAERS: 2US FAERS
282MonoplegiaFAERS: 2US FAERS
283Musculoskeletal PainFAERS: 2US FAERS
284Musculoskeletal stiffnessFAERS: 2US FAERS
285MyoclonusFAERS: 2

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CTD
US FAERS
286Neonatal disorderFAERS: 2US FAERS
287NervousnessFAERS: 2SIDER
US FAERS
288NeuralgiaFAERS: 2

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CTD
US FAERS
289Neurological examination abnormalFAERS: 2US FAERS
290No reaction on previous exposure to drugFAERS: 2US FAERS
291OpisthotonusFAERS: 2US FAERS
292Optic AtrophyFAERS: 2US FAERS
293Optic NeuropathyFAERS: 2US FAERS
294PO2 decreasedFAERS: 2OFFSIDES
US FAERS
295Posterior capsule ruptureFAERS: 2US FAERS
296Prescribed overdoseFAERS: 2US FAERS
297Product appearance confusionFAERS: 2US FAERS
298Product contaminationFAERS: 2US FAERS
299Product label confusionFAERS: 2US FAERS
300Product label issueFAERS: 2US FAERS
301Product prescribing errorFAERS: 2US FAERS
302Product taste abnormalFAERS: 2US FAERS
303Pulmonary EmbolismFAERS: 2US FAERS
304Pulmonary arterial pressure increasedFAERS: 2OFFSIDES
US FAERS
305QuadriplegiaFAERS: 216102894CTD
US FAERS
306Rash erythematousFAERS: 2US FAERS
307Renal tubular necrosisFAERS: 2OFFSIDES
US FAERS
308RetchingFAERS: 2US FAERS
309Retinal Vein OcclusionFAERS: 2US FAERS
310Retinal artery spasmFAERS: 2US FAERS
311Retinal pigment epitheliopathyFAERS: 2US FAERS
312Seizure like phenomenaFAERS: 2US FAERS
313Skin discomfortFAERS: 2US FAERS
314StridorFAERS: 2US FAERS
315Sudden Cardiac DeathFAERS: 2US FAERS
316Therapeutic product effect decreasedFAERS: 2US FAERS
317Therapy cessationFAERS: 2US FAERS
318TrismusFAERS: 2US FAERS
319UlcerFAERS: 2US FAERS
320Upper respiratory tract congestionFAERS: 2US FAERS
321Urinary RetentionFAERS: 2SIDER
US FAERS
322VasculitisFAERS: 2US FAERS
323Ventricular arrhythmiaFAERS: 2US FAERS
324Visceral congestionFAERS: 2US FAERS
325Visual disturbanceFAERS: 2SIDER
US FAERS
326AcneFAERS: 1OFFSIDES
US FAERS
327Allergic reaction to excipientFAERS: 1US FAERS
328AllodyniaFAERS: 1US FAERS
329Angina PectorisFAERS: 1US FAERS
330AnhedoniaFAERS: 1US FAERS
331Ankle FractureFAERS: 1US FAERS
332AnoxiaFAERS: 1US FAERS
333Application site burnFAERS: 1US FAERS
334Application site erosionFAERS: 1US FAERS
335Application site injuryFAERS: 1US FAERS
336Application site ulcerFAERS: 1US FAERS
337ArthropathyFAERS: 1US FAERS
338Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
339Band sensationFAERS: 1US FAERS
340Blood blisterFAERS: 1US FAERS
341Blood fibrinogen increasedFAERS: 1US FAERS
342Blood glucose decreasedFAERS: 1US FAERS
343Bone scan abnormalFAERS: 1US FAERS
344Brain AbscessFAERS: 1US FAERS
345Breakthrough PainFAERS: 1OFFSIDES
US FAERS
346BruxismFAERS: 1US FAERS
347Burns fourth degreeFAERS: 1US FAERS
348Cardiac DeathFAERS: 1US FAERS
349Cataract operation complicationFAERS: 1US FAERS
350CataractFAERS: 1US FAERS
351Cerebral gas embolismFAERS: 1US FAERS
352CheilitisFAERS: 1US FAERS
353ChromaturiaFAERS: 1US FAERS
354Citrobacter test positiveFAERS: 1US FAERS
355ColitisFAERS: 1US FAERS
356Corneal UlcerFAERS: 1US FAERS
357Corneal flap complicationFAERS: 1US FAERS
358Culture positiveFAERS: 1US FAERS
359DeafnessFAERS: 1US FAERS
360DehydrationFAERS: 1OFFSIDES
US FAERS
361DementiaFAERS: 1US FAERS
362DermatitisFAERS: 1SIDER
US FAERS
363Device adhesion issueFAERS: 1US FAERS
364Device difficult to useFAERS: 1US FAERS
365Device shape alterationFAERS: 1US FAERS
366Documented hypersensitivity to administered drugFAERS: 1US FAERS
367Documented hypersensitivity to administered productFAERS: 1US FAERS
368DroolingFAERS: 1US FAERS
369Drug administered to patient of inappropriate ageFAERS: 1US FAERS
370Drug effect variableFAERS: 1US FAERS
371Drug level below therapeuticFAERS: 1US FAERS
372Drug screen false positiveFAERS: 1US FAERS
373Dry skinFAERS: 1OFFSIDES
US FAERS
374DysphoniaFAERS: 1
Canada Vigilance: 1
15785267CTD
SIDER
Canada Vigilance
US FAERS
375Ear discomfortFAERS: 1US FAERS
376Economic problemFAERS: 1US FAERS
377Ejection Fraction DecreasedFAERS: 1US FAERS
378Electrocardiogram ST-T changeFAERS: 1US FAERS
379Electrocardiogram abnormalFAERS: 1US FAERS
380Electroencephalogram abnormalFAERS: 1US FAERS
381EmbolismFAERS: 1US FAERS
382Emotional distressFAERS: 1US FAERS
383Endothelial dysfunctionFAERS: 1US FAERS
384EpiglottitisFAERS: 1US FAERS
385EructationFAERS: 1US FAERS
386Erythema MultiformeFAERS: 118073329CTD
US FAERS
387Euphoric moodFAERS: 1
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
388EuthanasiaFAERS: 1US FAERS
389ExophthalmosFAERS: 1US FAERS
390Exposure to toxic agentFAERS: 1US FAERS
391Exposure via direct contactFAERS: 1US FAERS
392Exposure via ingestionFAERS: 1US FAERS
393Exposure via partnerFAERS: 1US FAERS
394Extra dose administeredFAERS: 1US FAERS
395Extremity necrosisFAERS: 1OFFSIDES
US FAERS
396Eye operation complicationFAERS: 1US FAERS
397Feeling jitteryFAERS: 1US FAERS
398Fibrin D dimer increasedFAERS: 1US FAERS
399FibromyalgiaFAERS: 112509636CTD
US FAERS
400Flail ChestFAERS: 1US FAERS
401Frustration tolerance decreasedFAERS: 1US FAERS
402GangreneFAERS: 1US FAERS
403General physical conditionFAERS: 1US FAERS
404General symptomFAERS: 1US FAERS
405Genital painFAERS: 1US FAERS
406Hallucinations, mixedFAERS: 1US FAERS
407Heart sounds abnormalFAERS: 1US FAERS
408HepatotoxicityFAERS: 1US FAERS
409HerniaFAERS: 1US FAERS
410Hip surgeryFAERS: 1US FAERS
411HypercapniaFAERS: 1US FAERS
412HypersomniaFAERS: 1US FAERS
413HyperthyroidismFAERS: 1US FAERS
414HyperventilationFAERS: 1US FAERS
415HypoperfusionFAERS: 1US FAERS
416HypophagiaFAERS: 1OFFSIDES
US FAERS
417HypopyonFAERS: 1US FAERS
418HyporeflexiaFAERS: 1US FAERS
419Hyporesponsive to stimuliFAERS: 1US FAERS
420Impaired quality of lifeFAERS: 1US FAERS
421Impaired work abilityFAERS: 1US FAERS
422Inability to afford medicationFAERS: 1US FAERS
423Incision site painFAERS: 1US FAERS
424Incorrect route of product administrationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
425Infantile apnoeic attackFAERS: 1US FAERS
426InflammationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
427Injection site irritationFAERS: 1US FAERS
428Injection site necrosisFAERS: 1US FAERS
429Injury associated with deviceFAERS: 1US FAERS
430Insurance issueFAERS: 1US FAERS
431Intentional product use issueFAERS: 1US FAERS
432Intercepted medication errorFAERS: 1US FAERS
433Intervertebral disc injuryFAERS: 1US FAERS
434Intraspinal abscessFAERS: 1US FAERS
435Joint stiffnessFAERS: 1US FAERS
436LacerationFAERS: 1US FAERS
437LagophthalmosFAERS: 1US FAERS
438Laryngeal discomfortFAERS: 1US FAERS
439Latex allergyFAERS: 1US FAERS
440Left Ventricular HypertrophyFAERS: 1US FAERS
441Lip exfoliationFAERS: 1US FAERS
442Local reactionFAERS: 1SIDER
US FAERS
443Loss of proprioceptionFAERS: 1US FAERS
444Macular degenerationFAERS: 1US FAERS
445Malabsorption from application siteFAERS: 1US FAERS
446Maternal exposure during deliveryFAERS: 1US FAERS
447MeningitisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
448Meniscus injuryFAERS: 1US FAERS
449MenorrhagiaFAERS: 1US FAERS
450Mental impairmentFAERS: 1US FAERS
451Miller Fisher SyndromeFAERS: 1US FAERS
452MoaningFAERS: 1US FAERS
453Multiple use of single-use productFAERS: 1US FAERS
454Muscle CrampFAERS: 1US FAERS
455Muscle fibrosisFAERS: 1US FAERS
456Musculoskeletal chest painFAERS: 1US FAERS
457Musculoskeletal discomfortFAERS: 1US FAERS
458MutismFAERS: 1US FAERS
459Myocardial fibrosisFAERS: 1US FAERS
460MyositisFAERS: 1736396CTD
US FAERS
461NasopharyngitisFAERS: 1US FAERS
462NephrectomyFAERS: 1US FAERS
463NocturiaFAERS: 1US FAERS
464Ocular HypertensionFAERS: 1US FAERS
465Ocular discomfortFAERS: 1US FAERS
466Open woundFAERS: 1US FAERS
467OphthalmoplegiaFAERS: 1
Canada Vigilance: 1
2754483CTD
Canada Vigilance
US FAERS
468Optic nerve cuppingFAERS: 1US FAERS
469Oral fungal infectionFAERS: 1US FAERS
470Oral painFAERS: 1US FAERS
471OsteomyelitisFAERS: 1OFFSIDES
US FAERS
472OsteopeniaFAERS: 1US FAERS
473OsteoporosisFAERS: 1US FAERS
474PapuleFAERS: 1SIDER
US FAERS
475Perforated ulcerFAERS: 1US FAERS
476Phrenic nerve paralysisFAERS: 1US FAERS
477Physical product label issueFAERS: 1US FAERS
478PneumothoraxFAERS: 1US FAERS
479Poor quality sleepFAERS: 1US FAERS
480Post abortion complicationFAERS: 1US FAERS
481Posterior capsule opacificationFAERS: 1US FAERS
482Preoperative CareFAERS: 1US FAERS
483Product administered to patient of inappropriate ageFAERS: 1US FAERS
484Product administration errorFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
485Product compounding quality issueFAERS: 1US FAERS
486Product design issueFAERS: 1US FAERS
487Product measured potency issueFAERS: 1US FAERS
488Product package associated injuryFAERS: 1US FAERS
489Product packaging difficult to openFAERS: 1US FAERS
490Product prescribing issueFAERS: 1US FAERS
491Product tamperingFAERS: 1US FAERS
492Psychiatric symptomFAERS: 1US FAERS
493PurpuraFAERS: 118450903CTD
US FAERS
494QRS axis abnormalFAERS: 1US FAERS
495QuadriparesisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
496Quality of life decreasedFAERS: 1US FAERS
497Radicular painFAERS: 1US FAERS
498Reaction to drug excipientsFAERS: 1US FAERS
499Reaction to excipientFAERS: 1US FAERS
500Rectal ProlapseFAERS: 1US FAERS
501Renal painFAERS: 1US FAERS
502Restless Legs SyndromeFAERS: 1US FAERS
503Retinal Vascular DisorderFAERS: 1US FAERS
504Retinal exudatesFAERS: 1US FAERS
505Retinal toxicityFAERS: 1US FAERS
506Retinogram abnormalFAERS: 1US FAERS
507RhabdomyolysisFAERS: 1US FAERS
508Rheumatic Heart DiseaseFAERS: 1US FAERS
509Right hemisphere deficit syndromeFAERS: 1US FAERS
510ScabFAERS: 1US FAERS
511Sense of oppressionFAERS: 1US FAERS
512Sexual DysfunctionFAERS: 1US FAERS
513Shoulder PainFAERS: 115785267CTD
US FAERS
514Sinoatrial BlockFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
515Sinus rhythmFAERS: 1US FAERS
516SinusitisFAERS: 1US FAERS
517Skin lacerationFAERS: 1US FAERS
518Skin test positiveFAERS: 1US FAERS
519Slow speechFAERS: 1US FAERS
520Staphylococcus test positiveFAERS: 1US FAERS
521Status AsthmaticusFAERS: 1US FAERS
522Streptococcus test positiveFAERS: 1US FAERS
523Subcutaneous AbscessFAERS: 1US FAERS
524Surgical failureFAERS: 1US FAERS
525Suspected transmission of an infectious agent via productFAERS: 1US FAERS
526Suture insertionFAERS: 1US FAERS
527Therapeutic product contaminationFAERS: 1US FAERS
528Therapy changeFAERS: 1US FAERS
529ThirstFAERS: 1US FAERS
530Thrombosis in deviceFAERS: 1US FAERS
531ThrombosisFAERS: 1US FAERS
532ToothacheFAERS: 1US FAERS
533Transient aphasiaFAERS: 1US FAERS
534Troponin increasedFAERS: 1US FAERS
535Upper airway obstructionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
536Urethral spasmFAERS: 1US FAERS
537Urinary IncontinenceFAERS: 1SIDER
US FAERS
538VIIth nerve paralysisFAERS: 1US FAERS
539Ventricular failureFAERS: 1US FAERS
540Victim of homicideFAERS: 1US FAERS
541Vitreous floatersFAERS: 1US FAERS
542Wound InfectionFAERS: 1US FAERS
543Wound necrosisFAERS: 1US FAERS
544Wrong patient received medicationFAERS: 1US FAERS
545Wrong patient received productFAERS: 1US FAERS
546Wrong technique in device usage processFAERS: 1US FAERS
547YawningFAERS: 1US FAERS
548jaundiceFAERS: 1US FAERS
549Abdominal AbscessOFFSIDES
550Abducens Nerve Diseases17220849CTD
551AcidosisOFFSIDES
SIDER
552ActinomycosisOFFSIDES
553Acute sinusitisOFFSIDES
554Adiposis Dolorosa2430406CTD
555Akathisia, Drug-Induced9700044CTD
556Anemia5313657CTD
557Anoxic EncephalopathyOFFSIDES
558Anterior Spinal Artery SyndromeSIDER
559Anxiety Disorders3812782CTD
560Aortic valve sclerosisOFFSIDES
561Aphonia1343088CTD
SIDER
562Aphthous StomatitisOFFSIDES
563Apnea

View details

CTD
OFFSIDES
564AppendectomyOFFSIDES
565ArachnoiditisSIDER
566Aspiration PneumoniaOFFSIDES
567AstigmatismOFFSIDES
568Band neutrophil count increasedOFFSIDES
569Beta 2 microglobulin increasedOFFSIDES
570Beta-N-acetyl-D-glucosaminidase increasedOFFSIDES
571Bidirectional tachycardia7082511CTD
572Biopsy bone abnormalOFFSIDES
573BiopsyCanada Vigilance: 1Canada Vigilance
OFFSIDES
574Bipolar Disorder2286718CTD
575Blepharoptosis3395920CTD
576Blood GlucoseOFFSIDES
577Blood albumin decreasedOFFSIDES
578Blood chromogranin A increasedOFFSIDES
579Blood gases abnormalOFFSIDES
580Blood potassium decreasedOFFSIDES
581Blood urine presentOFFSIDES
582Body TemperatureOFFSIDES
583Brain Injuries17689565CTD
584Brain Ischemia16192539CTD
585BronchitisOFFSIDES
586Bundle-Branch Block2782658CTD
587CD4 Lymphocytes DecreasedOFFSIDES
588CNS toxicitySIDER
589CandiduriaOFFSIDES
590Cardiovascular Diseases17277955
19250287
CTD
591Cauda Equina SyndromeSIDER
592Causalgia17251215CTD
OFFSIDES
593CellulitisOFFSIDES
594Central line infectionOFFSIDES
595Cerebellar Ataxia15039479CTD
596Cholelithiasis obstructiveOFFSIDES
597Circumoral paresthesiaSIDER
598Cocaine-Related Disorders11826141
14614084
17156389
CTD
599Confusion3812782
4968192
CTD
600Conjunctival depositOFFSIDES
601Contact DermatitisOFFSIDES
602Coronary artery perforationOFFSIDES
603Dental abscessOFFSIDES
604Diabetic Neuropathies15210530CTD
605DiarrheaOFFSIDES
606Disorders of Excessive Somnolence6886235
16043000
CTD
607Disseminated Intravascular CoagulationOFFSIDES
608DiverticulumOFFSIDES
609DrowsinessSIDER
610Drug Eruptions1371395
11792017
CTD
611Dyspareunia7771004CTD
612DyspepsiaOFFSIDES
613DystoniaOFFSIDES
614DysuriaOFFSIDES
615Edema11217590CTD
616Endotracheal tube obstructionSIDER
617Erectile dysfunction439362
7771004
CTD
618Erythema Nodosum18073329CTD
619Erythromelalgia22170168CTD
620ExcoriationOFFSIDES
621Facial Nerve Injuries14689429CTD
622Failure of implantOFFSIDES
623Febrile NeutropeniaOFFSIDES
624Feeding and Eating Disorders6952075CTD
625Flank PainOFFSIDES
626Food PoisoningOFFSIDES
627Gait Ataxia407834CTD
628Gastrointestinal motility disorderOFFSIDES
629Gingivitis11217590CTD
SIDER
630Gum neoplasm malignant stage unspecifiedOFFSIDES
631Hallucinations3812782CTD
632Heart Block

View details

CTD
633Heart Diseases24323366CTD
634Heart failure3510989
7712677
CTD
635Heparin-induced thrombocytopeniaOFFSIDES
636Hepatic InfarctionOFFSIDES
637HiccoughOFFSIDES
638HidradenitisOFFSIDES
639HoarsenessSIDER
640Horner Syndrome10051945CTD
641HydronephrosisOFFSIDES
642HyperacusisSIDER
643Hyperalgesia

View details

CTD
644Hypertrophic CardiomyopathyOFFSIDES
645Hypesthesia6886235CTD
646Hypokalemia8669646CTD
647Implant site swellingOFFSIDES
648Incision site infectionOFFSIDES
649Increased upper airway secretionOFFSIDES
650Injection site infectionOFFSIDES
651Injection site warmthOFFSIDES
652Intestinal FistulaOFFSIDES
653Intestinal infarctionOFFSIDES
654Joint sprainOFFSIDES
655Kidney FailureOFFSIDES
656Labor Pain4931162
18326251
CTD
657LeukodermaSIDER
658LightheadednessSIDER
659Low Back Pain12500518
17698525
18599578
CTD
660Lymphoma, Non-Hodgkin8834551CTD
661MeningismSIDER
662Meniscus removalOFFSIDES
663Mental disorders16982355
19250287
CTD
664Mesenteric vascular insufficiencyOFFSIDES
665Metastases to abdominal cavityOFFSIDES
666Metastatic NeoplasmOFFSIDES
667Metastatic Renal Cell CarcinomaOFFSIDES
668Methemoglobinemia3537620
17612444
CTD
669Mole excisionOFFSIDES
670Mouth irritationSIDER
671Multiple MyelomaOFFSIDES
672Muscle Spasticity2008943CTD
673Muscle hypotonia407834
18406071
CTD
674Muscle necrosisOFFSIDES
675MyelodysplasiaOFFSIDES
676Myofascial Pain Syndromes19446144CTD
677MyringitisOFFSIDES
678Nerve Degeneration11799506
16037173
CTD
679Neural Tube Defects7462985CTD
680Neuritis19224819CTD
681Neurologic Manifestations

View details

CTD
682Neurologic reactionSIDER
683Neuropathic painOFFSIDES
684NeuropathySIDER
685Neutrophil count decreasedOFFSIDES
686Numbness of tongueSIDER
687NumbnessSIDER
688Obsessive thoughtsOFFSIDES
689ObstructionSIDER
690OculogyrationOFFSIDES
691Olfaction Disorders16286355CTD
692OliguriaOFFSIDES
693Oropharyngeal painOFFSIDES
SIDER
694Osteitis DeformansOFFSIDES
695Osteochondrodysplasias12238912CTD
696Ovarian enlargementOFFSIDES
697Pain worsenedSIDER
698Pain, Intractable11280320CTD
699Pain, Postoperative

View details

CTD
700Paresis843977
16834790
CTD
701Paresthesia

View details

CTD
702Pelvic Pain18287220CTD
703Performance status decreasedOFFSIDES
704Pericardial effusionOFFSIDES
705Peripheral Nervous System Diseases

View details

CTD
706Peripheral Vascular Diseases3564823CTD
707Personality Disorders1168209CTD
708PetechiaeSIDER
709Phlebitis6617280CTD
710PiloerectionOFFSIDES
711PlasmacytomaOFFSIDES
712Polyradiculopathy10225068CTD
713Positron emission tomogram abnormalOFFSIDES
714Post procedural hypothyroidismOFFSIDES
715Post transplant distal limb syndromeOFFSIDES
716Postoperative Complications3395920
9466098
11172519
CTD
717Postoperative Nausea and Vomiting5090228CTD
718PregnancySIDER
719Prenatal Exposure Delayed Effects3703096CTD
720Prenatal Injuries24323366CTD
721Primary sequestrumOFFSIDES
722Protein total decreasedOFFSIDES
723Psychoses, Substance-Induced3563280
3812782
CTD
724Psychotic Disorders18486797CTD
725Pulmonary Edema12509636
14762759
CTD
726Pulmonary function test decreasedSIDER
727PyelonephritisOFFSIDES
728Radiculopathy8862655
9924248
11899459
CTD
729RednessSIDER
730Reflex Sympathetic Dystrophy15271746
16115995
CTD
731Renal tubular disorderOFFSIDES
732Respiratory Insufficiency

View details

CTD
733Respiratory Paralysis945016
1343088
CTD
SIDER
734RetrocollisOFFSIDES
735RhinitisSIDER
736Seizures

View details

CTD
737Sensation Disorders

View details

CTD
738ShiveringSIDER
739Shock, Cardiogenic7154501CTD
740Sinus Arrest, Cardiac7097935
7148661
7344095
CTD
741Situs Inversus9856732CTD
742Skin irritationSIDER
743Slurred speechSIDER
744Soft Tissue InjuriesOFFSIDES
745Spasm414595
3564823
16176311
CTD
746Speech Disorders3563280CTD
747Spinal Cord Diseases171983
5487723
CTD
748Spinal Cord Injuries30240660CTD
749Spinal claudicationOFFSIDES
750Splenic InfarctionOFFSIDES
751Splenic abscessOFFSIDES
752StomatitisSIDER
753StuporCanada Vigilance: 1Canada Vigilance
754Tachycardia, Ventricular

View details

CTD
755Taste Disorders8403154CTD
756TensionSIDER
757Therapeutic product effect incompleteCanada Vigilance: 1Canada Vigilance
758Tooth ErosionOFFSIDES
759Tooth ExtractionOFFSIDES
760Torsades de Pointes

View details

CTD
761Tracheal StenosisOFFSIDES
762TracheitisOFFSIDES
763TracheobronchitisOFFSIDES
764Upper respiratory tract infection bacterialOFFSIDES
765Vascular calcificationOFFSIDES
766Venipuncture site hemorrhageSIDER
767Ventricular Dysfunction7415933CTD
768Vision Disorders9292686CTD
769Vulvovaginal discomfortCanada Vigilance: 1Canada Vigilance
770Weight GainOFFSIDES
771anaphylaxis2806083
14688599
CTD
772apprehensionSIDER
773colonoscopyOFFSIDES
774kyphosisOFFSIDES
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