MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

bisphenol A

(IISBACLAFKSPIT-UHFFFAOYSA-N)

Structure

SMILES: CC(c1ccc(cc1)O)(c1ccc(cc1)O)C
Type(s): Experimental
Molecular Formula:: C15H16O2
Molecular Weight:: 228.286
Log P:: 3.4237
Hydrogen Bond Acceptor:: 2
Hydrogen Bond Donor:: 2
TPSA:: 40.46
CAS Number(s):: 80-05-7; 27100-33-0

Synonym(s)

bisphenol A

2,2-bis(4-hydroxyphenyl)propane

4,4'-dihydroxy-2,2-diphenylpropane

bisphenol A, disodium salt

bisphenol A, sodium salt

diphenylolpropane

External Link(s)

MeSH	C006780
PubChem Compound	6623
BindingDB	29608
ChEBI	33216
CHEMBL	CHEMBL418971
DrugBank	DB06973
IUPHAR/BPS Guide to PHARMACOLOGY	7865
KEGG	cpd:C13624
Therapeutic Target Database	D02RQP
ZINC	56434

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abnormalities, Drug-Induced	View details 20299547 20970156 21269433 25853433 29458080	CTD
2	Acute kidney injury	24625398	CTD
3	Adenocarcinoma	View details 19590677 23810794 27721470 30387366 31287222	CTD
4	Albuminuria	22398408	CTD
5	Aneuploidy	18225860 30763314	CTD
6	Angina Pectoris	20084273	CTD
7	Anxiety Disorders	View details 22957036 23240141 23716699 23791455 23871786 24323913 25112706 25242006 25307304 25812946 26060449 28089772 28641223 30312744	CTD
8	Arrest of spermatogenesis	25181051	CTD
9	Asthenozoospermia	25461564 25772901 27296223	CTD
10	Atherosclerosis	21621210 24755147	CTD
11	Attention Deficit and Disruptive Behavior Disorders	25307304	CTD
12	Autoimmune Diseases	27869686	CTD
13	Birth Weight	22050967 29129240	CTD
14	Body Weight Changes	24496637 30496632	CTD
15	Body Weight	24705360 24768697	CTD
16	Bone Diseases, Developmental	29732168	CTD
17	Bone Resorption	11985600	CTD
18	Bradycardia	27486708	CTD
19	Brain Injuries	30997025	CTD
20	Bronchial Hyperreactivity	20123615	CTD
21	Camptocormia	30075455	CTD
22	Carcinoma in Situ	17123778	CTD
23	Cardiomegaly	25594700	CTD
24	Cardiomyopathy, Dilated	25996886	CTD
25	Carotid Stenosis	21621210	CTD
26	Chemical and Drug Induced Liver Injury	View details 24625398 24981242 26450347 27925325 28689058 28959593 29933238 30057697 30997025 31319301 31470036	CTD
27	Child Behavior Disorders	22707478	CTD
28	Chromosome Aberrations	21059909 24085620 27472198	CTD
29	Chromosome Breakage	25933419 27299659 29192164	CTD
30	Cognition Disorders	20169576 21971502 26139607	CTD
31	Colonic Diseases	31394344	CTD
32	Conduct Disorder	25307304	CTD
33	Congenital, Hereditary, and Neonatal Diseases and Abnormalities	27841950	CTD
34	Coronary Artery Disease	22354940	CTD
35	Craniofacial Abnormalities	View details 22194820 23637088 29016128 30075455	CTD
36	Cystadenoma	19590677	CTD
37	Demyelinating Diseases	24191696 31574244	CTD
38	Dental Enamel Hypoplasia	23764278 27257137 27352425	CTD
39	Depressive disorder	23240141 25112706 26060449	CTD
40	Diabetes Mellitus	20084273 21956417	CTD
41	Disease Progression	23810794	CTD
42	Dyslipidemias	27502578 27806752	CTD
43	Edema, Cardiac	26322593 29016128 31126002	CTD
44	Edema	View details 15364205 20728951 22194820 23637088 23821587 24992288 26450347	CTD
45	Embryo Loss	View details 23653003 26712470 27314163 27472198 29397701 30248606	CTD
46	Endometrial Hyperplasia	28959593	CTD
47	Endometriosis	25205760 28400829	CTD
48	Erectile dysfunction	20467048	CTD
49	Eye Abnormalities	19218331	CTD
50	Fatty Liver	View details 24768697 24793377 26382854 27014939 27322340 28500084 28796629 29933238	CTD
51	Feminization	22692143	CTD
52	Fetal Death	24576723	CTD
53	Fetal Growth Retardation	27623287	CTD
54	Fetal Weight	24496637	CTD
55	Fibrosis	27025157 30809271	CTD
56	Gliosis	30997025	CTD
57	Glucose Metabolism Disorders	23493373	CTD
58	Gonadal Disorders	19479018	CTD
59	Heart Diseases	27025157	CTD
60	Heart Injuries	30496632 31126002	CTD
61	Hemorrhage	20728951 29016128	CTD
62	Hepatomegaly	View details 25112833 27502578 28483554 30579156 31352099 31424294	CTD
63	Hyperalgesia	31574244	CTD
64	Hypercholesterolemia	25168180	CTD
65	Hyperemia	29558425	CTD
66	Hyperglycemia	View details 24705360 24959901 25168180 31344369	CTD
67	Hyperinsulinism	View details 27145005 27502578 28153594 28483554	CTD
68	Hyperphagia	27809950 28079927	CTD
69	Hyperplasia	View details 9607780 18938238 20350546 24257414 24520039 24988533 26098999 26877094	CTD
70	Hyperprolactinemia	11108262	CTD
71	Hypertrophy	9607780 18445619 25878060	CTD
72	Hypogonadism	24134786	CTD
73	Hypospadias	25434310	CTD
74	Hypotension	25594700	CTD
75	Immunologic Deficiency Syndromes	29195089	CTD
76	Infant Death	28393075	CTD
77	Infertility	21059909 27120497	CTD
78	Inflammation	View details 20018722 24191696 24257414 27145005 27925325 29148069 29161229 31574244	CTD
79	Insulin Resistance	View details 16393666 20488778 22470480 23424204 23748860 24705360 24793715 26923231 27187765 28153594 28483554 28739533 28774890 29793316 29935216 30208560	CTD
80	Kidney Diseases	View details 18445619 23359474 30303745 30997025	CTD
81	Liver Cirrhosis, Experimental	27925325	CTD
82	Liver Neoplasms, Experimental	27334623	CTD
83	Liver neoplasms	24487385	CTD
84	Lung Injury	30997025	CTD
85	Lung Neoplasms	27506545	CTD
86	Lymphatic Metastasis	31143956	CTD
87	Mammary Neoplasms, Experimental	22649256 28487351 28844962	CTD
88	Memory Disorders	View details 17467901 20169576 20206181 20219646 22484357 23523742 24820113 25074486 25084756 25242006 25963729 26827910 28572023 28852612 30312744 31574244	CTD
89	Mental disorders	23716699 24820113	CTD
90	Metabolic Diseases	24793377	CTD
91	Microcephaly	15364205	CTD
92	Micronuclei, Chromosome-Defective	23142537	CTD
93	Migraine Disorders	24189132	CTD
94	Mood Disorders	29778459	CTD
95	Motor Skills Disorders	31574244	CTD
96	Myocardial Infarction	20084273	CTD
97	Myocarditis	22718145 31551929	CTD
98	Myoma	23915859	CTD
99	Necrosis	17493787 26063408 26450347	CTD
100	Neoplasm Invasiveness	View details 25312822 26546977 27366082 28466560	CTD
101	Neoplasm Metastasis	21988766	CTD
102	Neoplasms, Experimental	24424067 29050248	CTD
103	Nerve Degeneration	25381574 30997025 31574244	CTD
104	Neurobehavioral Manifestations	24953688	CTD
105	Neuroblastoma	27366082	CTD
106	Neurologic Manifestations	20049216	CTD
107	Neurotoxicity Syndromes	29782159	CTD
108	Non-alcoholic Fatty Liver Disease	28483554	CTD
109	Obesity, Abdominal	21676388	CTD
110	Obesity	View details 21676388 22852093 23558351 23958765 24981242 25807043 27502578 27809950 28079927 30722647	CTD
111	Oligospermia	View details 19782717 23528252 23554804 24085620 25461564 27296223 30275377	CTD
112	Osteosarcoma	23886186	CTD
113	Ovarian Cysts	19590677 31129395	CTD
114	Ovarian Diseases	View details 11985600 22187349 23359474 24496637 28393075 28959593 31424294	CTD
115	Overweight	23776476	CTD
116	Parasitic Diseases, Animal	31291264	CTD
117	Pericarditis	31551929	CTD
118	Pigmentation Disorders	19218331 21269433	CTD
119	Pituitary Diseases	19479018	CTD
120	Plaque, Atherosclerotic	21621210 29425287	CTD
121	Pneumonia	28285737	CTD
122	Poisoning	View details 27750016 28728110 29604499 29621162	CTD
123	Pre-Eclampsia	27177253	CTD
124	Precancerous Conditions	26898831 29148069	CTD
125	Premature Birth	23545179	CTD
126	Prenatal Exposure Delayed Effects	View details 10188188 10548101 15548368 18445619 19590677 20049216 20123615 20393758 20413367 20488778 20675265 21126938 21513798 21761357 21829099 21900077 21980460 22050967 22187349 22302688 22484357 22543054 22566636 22687993 22875908 22938446 23359474 23493373 23653003 23716699 23719926 23748860 23764278 24036610 24105817 24323913 24403293 24576723 24726836 24768697 24793715 24820113 24857958 24923655 24959901 24988533 25112833 25242006 25385582 25666754 25807043 25812946 26060449 26260748 26427651 26746108 26827910 26911702 27178563 27257137 27296223 27312807 27571134 27623287 27693988 27697584 27806752 27809950 27836638 27841950 28079927 28089772 28279065 28393075 28445388 28476547 28487351 28637469 28970132 29097150 29161229 29165653 29220483 29718165 29721103 30075455 30185693 30208560 30275377 30755151 30761779 30816183 30853570 31188430 31201698 31263496	CTD
127	Prenatal Injuries	View details 22426297 23337607 23557687 23637088 24953688 26283537 28938483	CTD
128	Prolactinoma	27830003	CTD
129	Prostatic Diseases	15867144 23359474	CTD
130	Prostatic Hyperplasia	View details 26260748 28928807 29323181 30822521	CTD
131	Prostatic Neoplasms	View details 16740699 21536718 24424067 27998958 29148069 30387366	CTD
132	Proteinuria	24809654	CTD
133	Psychomotor Agitation	25074486 25583509	CTD
134	Pulmonary Edema	30997025	CTD
135	Pulmonary Fibrosis	28285737	CTD
136	Purpura	29558425	CTD
137	Sarcoma	19590677	CTD
138	Somatosensory Disorders	22194820	CTD
139	Substance-Related Disorders	16045194 16684133	CTD
140	Teratogenesis	29016128	CTD
141	Teratozoospermia	30275377 30755151	CTD
142	Testicular Diseases	View details 19193734 23359474 27539358 27855330 28393075 30228064 30526071 30997025 31319301 31352104 31369804	CTD
143	Thyroid Diseases	30352396	CTD
144	Urethral stricture	15867144	CTD
145	Urogenital Abnormalities	10806412 22687993	CTD
146	Uterine Anomalies	25666754	CTD
147	Uterine Diseases	View details 14652134 20393758 20599497 21532259	CTD
148	Uterine Neoplasms	23915859	CTD
149	Vascular Diseases	24305612	CTD
150	Vestibular Diseases	21269433	CTD
151	Weight Gain	View details 20019905 23418087 24959901 25112833 26088557 26944108 26996129 27145005 27693988 27806752 28079927 28483554 28774890 28796629 29220483 29721103 30057697 30352396 31352104	CTD
152	prostatitis	26260748	CTD

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