MetaADEDB 2.0 @ LMMD
Perindopril
(IYNMDWMQHSMDDE-MHXJNQAMSA-N)
Structure
SMILES
CC(N)(C)C.CCC[C@@H](C(=O)OCC)N[C@H](C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O)C
Molecular Formula:
C23H43N3O5
Molecular Weight:
441.605
Log P:
3.7133
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
3
TPSA:
121.96
CAS Number(s):
107133-36-8
Synonym(s)
1.
Perindopril
2.
Perindopril Erbumine
3.
Perstarium
4.
Pirindopril
5.
S 9490-3
6.
S-9490
7.
Erbumine, Perindopril
8.
S 9490
9.
S 9490 3
10.
S 94903
11.
S9490
External Link(s)
MeSHD020913
PubChem Compound441313
BindingDB50248096
ChEBI8025
CHEMBLCHEMBL1200343
KEGGcpd:C07707
dr:D00624
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AngioedemaFAERS: 42US FAERS
2Drug ineffectiveFAERS: 15US FAERS
3UrticariaFAERS: 11US FAERS
4PruritusFAERS: 9US FAERS
5DizzinessFAERS: 7OFFSIDES
US FAERS
6VomitingFAERS: 7US FAERS
7BronchospasmFAERS: 6US FAERS
8NauseaFAERS: 6US FAERS
9PalpitationsFAERS: 6US FAERS
10Chest discomfortFAERS: 5US FAERS
11FatigueFAERS: 5US FAERS
12HeadacheFAERS: 5US FAERS
13HypersensitivityFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
14Product substitution issueFAERS: 5US FAERS
15Pulmonary FibrosisFAERS: 5US FAERS
16TinnitusFAERS: 5US FAERS
17Angina PectorisFAERS: 4US FAERS
18AnxietyFAERS: 4US FAERS
19Cerebrovascular accidentFAERS: 4US FAERS
20Lip swellingFAERS: 4US FAERS
21SyncopeFAERS: 4US FAERS
22Abdominal PainFAERS: 3US FAERS
23BronchiectasisFAERS: 3US FAERS
24Coronary Artery DiseaseFAERS: 3US FAERS
25DehydrationFAERS: 3OFFSIDES
US FAERS
26EpilepsyFAERS: 3US FAERS
27Joint swellingFAERS: 3US FAERS
28MalaiseFAERS: 3US FAERS
29MyalgiaFAERS: 3US FAERS
30PancreatitisFAERS: 3US FAERS
31PneumoniaFAERS: 3US FAERS
32Urinary tract infectionFAERS: 3US FAERS
33VertigoFAERS: 3US FAERS
34Alanine Aminotransferase IncreasedFAERS: 2US FAERS
35Amaurosis FugaxFAERS: 2US FAERS
36AstheniaFAERS: 2OFFSIDES
US FAERS
37AsthmaFAERS: 2OFFSIDES
US FAERS
38BradyphreniaFAERS: 2US FAERS
39CellulitisFAERS: 2US FAERS
40Chest PainFAERS: 2US FAERS
41ConstipationFAERS: 2US FAERS
42DisorientationFAERS: 2US FAERS
43DiverticulitisFAERS: 2US FAERS
44Erythema MultiformeFAERS: 2US FAERS
45ErythemaFAERS: 2US FAERS
46Feeling abnormalFAERS: 2US FAERS
47Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
48IncoherentFAERS: 2US FAERS
49Incorrect dose administeredFAERS: 2US FAERS
50LymphadenopathyFAERS: 2US FAERS
51Memory impairmentFAERS: 2US FAERS
52Myocardial InfarctionFAERS: 2US FAERS
53No adverse eventFAERS: 2US FAERS
54Oropharyngeal painFAERS: 2US FAERS
55Pancreatic PseudocystFAERS: 2US FAERS
56Personality ChangeFAERS: 2US FAERS
57Productive CoughFAERS: 2US FAERS
58Rash erythematousFAERS: 2US FAERS
59Renal ColicFAERS: 2US FAERS
60SepsisFAERS: 2US FAERS
61SomnolenceFAERS: 2US FAERS
62StomatitisFAERS: 2US FAERS
63StridorFAERS: 2US FAERS
64Suicide attemptFAERS: 2US FAERS
65Thought insertionFAERS: 2US FAERS
66Throat irritationFAERS: 2US FAERS
67Abdominal discomfortFAERS: 1US FAERS
68AbscessFAERS: 1US FAERS
69AcarodermatitisFAERS: 1US FAERS
70Accidental exposure to product by childFAERS: 1US FAERS
71Acute kidney injuryFAERS: 1US FAERS
72Acute myocardial infarctionFAERS: 1US FAERS
73AgitationFAERS: 1US FAERS
74Alcohol IntoleranceFAERS: 1US FAERS
75Alopecia universalisFAERS: 1US FAERS
76Amylase increasedFAERS: 1US FAERS
77Anaphylactic shockFAERS: 1US FAERS
78AphoniaFAERS: 1US FAERS
79AppendicitisFAERS: 1US FAERS
80ArthralgiaFAERS: 1US FAERS
81ArthritisFAERS: 1US FAERS
82Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
83Atrial FibrillationFAERS: 1US FAERS
84Autoimmune thyroiditisFAERS: 1US FAERS
85Back PainFAERS: 1US FAERS
86BlindnessFAERS: 1US FAERS
87Blood alkaline phosphatase increasedFAERS: 1US FAERS
88Blood bicarbonate abnormalFAERS: 1US FAERS
89Blood creatine phosphokinase increasedFAERS: 1US FAERS
90Blood creatinine increasedFAERS: 1US FAERS
91Blood pressure inadequately controlledFAERS: 1US FAERS
92Bone swellingFAERS: 1US FAERS
93BradycardiaFAERS: 1OFFSIDES
US FAERS
94BronchitisFAERS: 1US FAERS
95BronchopneumoniaFAERS: 1US FAERS
96BursitisFAERS: 1US FAERS
97Cerebral PalsyFAERS: 1US FAERS
98Cerebral cystFAERS: 1US FAERS
99CheilitisFAERS: 1US FAERS
100CholelithiasisFAERS: 1US FAERS
101ChromaturiaFAERS: 1US FAERS
102ConjunctivitisFAERS: 1US FAERS
103Creatinine renal clearance increasedFAERS: 1US FAERS
104CyanosisFAERS: 1US FAERS
105Delusion of referenceFAERS: 1US FAERS
106Dermatitis acneiformFAERS: 1US FAERS
107DermatitisFAERS: 1US FAERS
108Diabetes MellitusFAERS: 1US FAERS
109Disease recurrenceFAERS: 1US FAERS
110Drug administration errorFAERS: 1US FAERS
111Drug exposure during pregnancyFAERS: 1US FAERS
112DyspepsiaFAERS: 1US FAERS
113DysphoniaFAERS: 1OFFSIDES
US FAERS
114EcchymosisFAERS: 1US FAERS
115Exposure via ingestionFAERS: 1US FAERS
116Feeling of body temperature changeFAERS: 1US FAERS
117GastritisFAERS: 1US FAERS
118GastroenteritisFAERS: 1US FAERS
119General physical health deteriorationFAERS: 1US FAERS
120GingivitisFAERS: 1US FAERS
121HepatitisFAERS: 1US FAERS
122HepatomegalyFAERS: 1US FAERS
123HordeolumFAERS: 1US FAERS
124Hypertensive crisisFAERS: 1US FAERS
125HyperthyroidismFAERS: 1US FAERS
126HypotensionFAERS: 1US FAERS
127HypothyroidismFAERS: 1US FAERS
128Impaired driving abilityFAERS: 1US FAERS
129Impaired work abilityFAERS: 1US FAERS
130Intrauterine infectionFAERS: 1US FAERS
131KeratitisFAERS: 1US FAERS
132Lower respiratory tract infectionFAERS: 1US FAERS
133Lower respiratory tract inflammationFAERS: 1OFFSIDES
US FAERS
134Lumbar herniaFAERS: 1US FAERS
135MacroglossiaFAERS: 1US FAERS
136MaculeFAERS: 1US FAERS
137Medication ErrorFAERS: 1US FAERS
138NasopharyngitisFAERS: 1US FAERS
139NephroangiosclerosisFAERS: 1US FAERS
140NephrolithiasisFAERS: 1US FAERS
141NervousnessFAERS: 1US FAERS
142NeutropeniaFAERS: 1US FAERS
143Non-cardiac chest painFAERS: 1US FAERS
144OverdoseFAERS: 1US FAERS
145PainFAERS: 1US FAERS
146PallorFAERS: 1OFFSIDES
US FAERS
147Pancreatic CystFAERS: 1US FAERS
148PancytopeniaFAERS: 1US FAERS
149Partner stressFAERS: 1US FAERS
150Poor quality drug administeredFAERS: 1US FAERS
151PregnancyFAERS: 1US FAERS
152PresyncopeFAERS: 1US FAERS
153Product formulation issueFAERS: 1US FAERS
154Product quality issueFAERS: 1US FAERS
155Rectal tenesmusFAERS: 1US FAERS
156Renal cystFAERS: 1US FAERS
157Respiratory distressFAERS: 1US FAERS
158RosaceaFAERS: 1US FAERS
159Septic ShockFAERS: 1US FAERS
160ShockFAERS: 1US FAERS
161Skin UlcerFAERS: 1US FAERS
162Skin reactionFAERS: 1US FAERS
163Small bowel angioedemaFAERS: 1US FAERS
164StressFAERS: 1US FAERS
165Sudden Cardiac DeathFAERS: 1US FAERS
166Sudden deathFAERS: 1US FAERS
167Suspected counterfeit productFAERS: 1US FAERS
168ThrombocytopeniaFAERS: 1US FAERS
169Thyroid NeoplasmFAERS: 1US FAERS
170TracheitisFAERS: 1US FAERS
171TremorFAERS: 1US FAERS
172Urinary RetentionFAERS: 1US FAERS
173Urine output increasedFAERS: 1US FAERS
174VIIth nerve paralysisFAERS: 1US FAERS
175Ventricular hypertrophyFAERS: 1US FAERS
176Viral upper respiratory tract infectionFAERS: 1US FAERS
177Visual ImpairmentFAERS: 1US FAERS
178WheezingFAERS: 1US FAERS
179ActinomycosisOFFSIDES
180Acute Coronary SyndromeOFFSIDES
181Alpha 2 globulin increasedOFFSIDES
182AlveolitisOFFSIDES
183Analgesic drug level increasedOFFSIDES
184AnhedoniaOFFSIDES
185AnuriaOFFSIDES
186ApathyOFFSIDES
187AthetosisOFFSIDES
188Atrial FlutterOFFSIDES
189BartholinitisOFFSIDES
190BicytopeniaOFFSIDES
191Biliary DyskinesiaOFFSIDES
192Blood albumin increasedOFFSIDES
193Blood chromogranin A increasedOFFSIDES
194Blood glucose decreasedOFFSIDES
195Blood magnesium decreasedOFFSIDES
196Blood phosphorus increasedOFFSIDES
197Blood sodiumOFFSIDES
198Blood triglycerides increasedOFFSIDES
199Bone painOFFSIDES
200Bunion operationOFFSIDES
201Cardioactive drug level increasedOFFSIDES
202Chronic left ventricular failureOFFSIDES
203ColitisOFFSIDES
204Contact DermatitisOFFSIDES
205Creatinine renal clearance decreasedOFFSIDES
206CystOFFSIDES
207Cytolytic hepatitisOFFSIDES
208DebridementOFFSIDES
209Dental cariesOFFSIDES
210Depressed Level of ConsciousnessOFFSIDES
211DermatomyositisOFFSIDES
212DiabetesOFFSIDES
213Diabetes mellitus inadequate controlOFFSIDES
214DiarrheaOFFSIDES
215DrowsinessOFFSIDES
216Duodenal UlcerOFFSIDES
217DuodenitisOFFSIDES
218DysgeusiaOFFSIDES
219Electrocardiogram poor R-wave progressionOFFSIDES
220Emotional distressOFFSIDES
221Eosinophilic myocarditisOFFSIDES
222ErythropeniaOFFSIDES
223Euphoric moodOFFSIDES
224ExcoriationOFFSIDES
225Exfoliative rashOFFSIDES
226FibromyalgiaOFFSIDES
227Fistula repairOFFSIDES
228FormicationOFFSIDES
229Gastric ulcerOFFSIDES
230Gastrointestinal stenosisOFFSIDES
231Hepatojugular refluxOFFSIDES
232HypercapniaOFFSIDES
233Immunosuppressant drug levelOFFSIDES
234Incision site infectionOFFSIDES
235IncontinenceOFFSIDES
236Incorrect drug administration rateOFFSIDES
237Infusion Site ExtravasationOFFSIDES
238Infusion site reactionOFFSIDES
239Intestinal ObstructionOFFSIDES
240Joint Range of Motion DecreasedOFFSIDES
241Kidney FailureOFFSIDES
242LethargyOFFSIDES
243LymphedemaOFFSIDES
244Malignant HypertensionOFFSIDES
245Mental impairmentOFFSIDES
246Muscle FatigueOFFSIDES
247Muscle tightnessOFFSIDES
248MyelodysplasiaOFFSIDES
249NeurodermatitisOFFSIDES
250Oral Cavity FistulaOFFSIDES
251OsteomyelitisOFFSIDES
252OverweightOFFSIDES
253PROTHROMBIN TIMEOFFSIDES
254PapillomaOFFSIDES
255Primary sequestrumOFFSIDES
256Prothrombin level decreasedOFFSIDES
257Psoas signOFFSIDES
258PsoriasisOFFSIDES
259Pulmonary sepsisOFFSIDES
260Purulent dischargeOFFSIDES
261Renal Artery StenosisOFFSIDES
262RhabdomyolysisOFFSIDES
263RhinorrheaOFFSIDES
264Scleroderma renal crisisOFFSIDES
265Silent myocardial infarctionOFFSIDES
266Skin lesionOFFSIDES
267Tardive DyskinesiaOFFSIDES
268Temperature intoleranceOFFSIDES
269ThrombophlebitisOFFSIDES
270Thrombosis in deviceOFFSIDES
271Toe operationOFFSIDES
272Tooth ExtractionOFFSIDES
273Tooth InfectionOFFSIDES
274Tooth LossOFFSIDES
275Vasculitic rashOFFSIDES
276Venous thrombosis limbOFFSIDES
277Ventricular FibrillationOFFSIDES
278kyphosisOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.