Fexofenadine hydrochloride and pseudoephedrine hydrochloride
(QFDDBBKJOGTVNI-PVTQAGNOSA-N)
Structure
- SMILES
- OC(=O)C(c1ccc(cc1)C(CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O)O)(C)C.CN[C@H]([C@H](c1ccccc1)O)C.Cl.Cl
- Molecular Formula:
- C42H56Cl2N2O5
- Molecular Weight:
- 739.810
- Log P:
- 8.7712
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 7
- TPSA:
- 113.26
- CAS Number(s):
- 616242-78-5
Synonym(s)
1.
Fexofenadine hydrochloride and pseudoephedrine hydrochloride
External Link(s)
| PubChem Compound | 9831873 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 492 Canada Vigilance: 36 | Canada Vigilance US FAERS | |
| 2 | Medication residue present | FAERS: 205 | US FAERS | |
| 3 | Feeling abnormal | FAERS: 121 | US FAERS | |
| 4 | Extra dose administered | FAERS: 70 | US FAERS | |
| 5 | Headache | FAERS: 67 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 6 | Dizziness | FAERS: 66 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 7 | Malaise | FAERS: 52 | US FAERS | |
| 8 | Nausea | FAERS: 46 | US FAERS | |
| 9 | Somnolence | FAERS: 41 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 10 | Feeling jittery | FAERS: 34 | US FAERS | |
| 11 | Wrong technique in drug usage process | FAERS: 34 | US FAERS | |
| 12 | Nervousness | FAERS: 30 | US FAERS | |
| 13 | Fatigue | FAERS: 26 | US FAERS | |
| 14 | Palpitations | FAERS: 26 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 15 | Constipation | FAERS: 25 | US FAERS | |
| 16 | Abdominal discomfort | FAERS: 24 | US FAERS | |
| 17 | Unevaluable event | FAERS: 24 | US FAERS | |
| 18 | Wrong technique in product usage process | FAERS: 23 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 19 | Product quality issue | FAERS: 21 | US FAERS | |
| 20 | Sneezing | FAERS: 21 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 21 | Anxiety | FAERS: 20 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 22 | Hypersensitivity | FAERS: 19 | US FAERS | |
| 23 | Product residue present | FAERS: 19 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 24 | Tremor | FAERS: 18 | US FAERS | |
| 25 | Drug effect incomplete | FAERS: 17 | US FAERS | |
| 26 | Dysuria | FAERS: 17 | US FAERS | |
| 27 | Expired product administered | FAERS: 17 | US FAERS | |
| 28 | Pruritus | FAERS: 16 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 29 | Adverse event | FAERS: 15 | US FAERS | |
| 30 | Product use issue | FAERS: 15 | US FAERS | |
| 31 | Vomiting | FAERS: 15 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 32 | Product taste abnormal | FAERS: 14 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 33 | Drug administration error | FAERS: 13 | US FAERS | |
| 34 | Oropharyngeal pain | FAERS: 12 | US FAERS | |
| 35 | Head discomfort | FAERS: 11 | US FAERS | |
| 36 | Restlessness | FAERS: 11 | US FAERS | |
| 37 | Agitation | FAERS: 10 | US FAERS | |
| 38 | Asthenia | FAERS: 10 | US FAERS | |
| 39 | Chest Pain | FAERS: 10 | US FAERS | |
| 40 | Choking | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 41 | Dyspepsia | FAERS: 10 | US FAERS | |
| 42 | Visual Impairment | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 43 | Dysphonia | FAERS: 9 | US FAERS | |
| 44 | Erythema | FAERS: 9 | US FAERS | |
| 45 | Inappropriate schedule of drug administration | FAERS: 9 | US FAERS | |
| 46 | Intentional product misuse | FAERS: 9 | US FAERS | |
| 47 | Medication residue | FAERS: 9 | US FAERS | |
| 48 | Pain | FAERS: 9 | US FAERS | |
| 49 | Urticaria | FAERS: 9 | US FAERS | |
| 50 | Abdominal Pain | FAERS: 8 | US FAERS | |
| 51 | Drug Dependence | FAERS: 8 | US FAERS | |
| 52 | Drug dose omission | FAERS: 8 | US FAERS | |
| 53 | Sinusitis | FAERS: 8 | US FAERS | |
| 54 | Chest discomfort | FAERS: 7 | US FAERS | |
| 55 | Dysgeusia | FAERS: 7 | US FAERS | |
| 56 | Eye irritation | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 57 | Pneumonia | FAERS: 7 | US FAERS | |
| 58 | Product use in unapproved indication | FAERS: 7 | US FAERS | |
| 59 | Sinus headache | FAERS: 7 | US FAERS | |
| 60 | Back Pain | FAERS: 6 | US FAERS | |
| 61 | Ear discomfort | FAERS: 6 | US FAERS | |
| 62 | Myocardial Infarction | FAERS: 6 | US FAERS | |
| 63 | Nasopharyngitis | FAERS: 6 | US FAERS | |
| 64 | Product packaging issue | FAERS: 6 | US FAERS | |
| 65 | Therapeutic response unexpected | FAERS: 6 | US FAERS | |
| 66 | Throat irritation | FAERS: 6 | US FAERS | |
| 67 | Disorientation | FAERS: 5 | US FAERS | |
| 68 | Euphoric mood | FAERS: 5 | US FAERS | |
| 69 | Foreign body trauma | FAERS: 5 | US FAERS | |
| 70 | Pharmaceutical product complaint | FAERS: 5 | US FAERS | |
| 71 | Product physical issue | FAERS: 5 | US FAERS | |
| 72 | Therapeutic reaction time decreased | FAERS: 5 | US FAERS | |
| 73 | Weight decreased | FAERS: 5 | US FAERS | |
| 74 | Aphonia | FAERS: 4 | US FAERS | |
| 75 | Asthma | FAERS: 4 | US FAERS | |
| 76 | Drug ineffective for unapproved indication | FAERS: 4 | US FAERS | |
| 77 | Epistaxis | FAERS: 4 | US FAERS | |
| 78 | Eye pain | FAERS: 4 | US FAERS | |
| 79 | Feeling Cold | FAERS: 4 | US FAERS | |
| 80 | Peripheral swelling | FAERS: 4 | US FAERS | |
| 81 | Product use complaint | FAERS: 4 | US FAERS | |
| 82 | Syncope | FAERS: 4 | US FAERS | |
| 83 | Tachycardia | FAERS: 4 | US FAERS | |
| 84 | Urinary Retention | FAERS: 4 | US FAERS | |
| 85 | Accidental overdose | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 86 | Amnesia | FAERS: 3 | US FAERS | |
| 87 | Cerebrovascular accident | FAERS: 3 | US FAERS | |
| 88 | Dark circles under eyes | FAERS: 3 | US FAERS | |
| 89 | Discomfort | FAERS: 3 | US FAERS | |
| 90 | Drug dispensing error | FAERS: 3 | US FAERS | |
| 91 | Drug effect delayed | FAERS: 3 | US FAERS | |
| 92 | Drug exposure during pregnancy | FAERS: 3 | US FAERS | |
| 93 | Hypotension | FAERS: 3 | US FAERS | |
| 94 | Incorrect dose administered | FAERS: 3 | US FAERS | |
| 95 | Lethargy | FAERS: 3 | US FAERS | |
| 96 | Medication Error | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 97 | Neck Pain | FAERS: 3 | US FAERS | |
| 98 | No adverse event | FAERS: 3 | US FAERS | |
| 99 | Overdose | FAERS: 3 | US FAERS | |
| 100 | Poor quality sleep | FAERS: 3 | US FAERS | |
| 101 | Tinnitus | FAERS: 3 | US FAERS | |
| 102 | Toothache | FAERS: 3 | US FAERS | |
| 103 | Urine flow decreased | FAERS: 3 | US FAERS | |
| 104 | Wheezing | FAERS: 3 | US FAERS | |
| 105 | Wrong drug administered | FAERS: 3 | US FAERS | |
| 106 | Accidental exposure to product by child | FAERS: 2 | US FAERS | |
| 107 | Amphetamines positive | FAERS: 2 | US FAERS | |
| 108 | Anger | FAERS: 2 | US FAERS | |
| 109 | Astigmatism | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 110 | Blood glucose increased | FAERS: 2 | US FAERS | |
| 111 | Bronchitis | FAERS: 2 | US FAERS | |
| 112 | Chromaturia | FAERS: 2 | US FAERS | |
| 113 | Cold sweat | FAERS: 2 | US FAERS | |
| 114 | Dehydration | FAERS: 2 | US FAERS | |
| 115 | Depressed mood | FAERS: 2 | US FAERS | |
| 116 | Diplopia | FAERS: 2 | US FAERS | |
| 117 | Disability | FAERS: 2 | US FAERS | |
| 118 | Drug screen positive | FAERS: 2 | US FAERS | |
| 119 | Dry skin | FAERS: 2 | US FAERS | |
| 120 | Feeling of body temperature change | FAERS: 2 | US FAERS | |
| 121 | Keratitis | FAERS: 2 | US FAERS | |
| 122 | Limb injury | FAERS: 2 | US FAERS | |
| 123 | Macular degeneration | FAERS: 2 | US FAERS | |
| 124 | Multiple allergies | FAERS: 2 | US FAERS | |
| 125 | Musculoskeletal stiffness | FAERS: 2 | US FAERS | |
| 126 | Myalgia | FAERS: 2 | US FAERS | |
| 127 | Nasal discomfort | FAERS: 2 | US FAERS | |
| 128 | Night sweats | FAERS: 2 | US FAERS | |
| 129 | Oral administration complication | FAERS: 2 | US FAERS | |
| 130 | Paranasal sinus discomfort | FAERS: 2 | US FAERS | |
| 131 | Poisoning | FAERS: 2 | US FAERS | |
| 132 | Product package associated injury | FAERS: 2 | US FAERS | |
| 133 | Product size issue | FAERS: 2 | US FAERS | |
| 134 | Product solubility abnormal | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 135 | Retching | FAERS: 2 | US FAERS | |
| 136 | Stillbirth | FAERS: 2 | US FAERS | |
| 137 | Swelling | FAERS: 2 | US FAERS | |
| 138 | Upper-airway cough syndrome | FAERS: 2 | US FAERS | |
| 139 | Vertigo | FAERS: 2 | US FAERS | |
| 140 | Abdominal rigidity | FAERS: 1 | US FAERS | |
| 141 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 142 | Activities of daily living impaired | FAERS: 1 | US FAERS | |
| 143 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 144 | Angle Closure Glaucoma | FAERS: 1 | US FAERS | |
| 145 | Anorexia | FAERS: 1 | US FAERS | |
| 146 | Aphagia | FAERS: 1 | US FAERS | |
| 147 | Aphasia | FAERS: 1 | US FAERS | |
| 148 | Apparent death | FAERS: 1 | US FAERS | |
| 149 | Arthralgia | FAERS: 1 | US FAERS | |
| 150 | Arthritis | FAERS: 1 | US FAERS | |
| 151 | Arthropathy | FAERS: 1 | US FAERS | |
| 152 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 153 | Benign Prostatic Hyperplasia | FAERS: 1 | US FAERS | |
| 154 | Bipolar Disorder | FAERS: 1 | US FAERS | |
| 155 | Blepharospasm | FAERS: 1 | US FAERS | |
| 156 | Blindness | FAERS: 1 | US FAERS | |
| 157 | Blood pressure immeasurable | FAERS: 1 | US FAERS | |
| 158 | Blood urine present | FAERS: 1 | US FAERS | |
| 159 | Bowel movement irregularity | FAERS: 1 | US FAERS | |
| 160 | Bradycardia | FAERS: 1 | US FAERS | |
| 161 | Bronchospasm | FAERS: 1 | US FAERS | |
| 162 | Burning sensation | FAERS: 1 | US FAERS | |
| 163 | Calcium deficiency | FAERS: 1 | US FAERS | |
| 164 | Cardiac Flutter | FAERS: 1 | US FAERS | |
| 165 | Cardiac discomfort | FAERS: 1 | US FAERS | |
| 166 | Cardiomegaly | FAERS: 1 | US FAERS | |
| 167 | Choking sensation | FAERS: 1 | US FAERS | |
| 168 | Chronic respiratory failure | FAERS: 1 | US FAERS | |
| 169 | Clostridium difficile infection | FAERS: 1 | US FAERS | |
| 170 | Complications of maternal exposure to therapeutic drugs | FAERS: 1 | US FAERS | |
| 171 | Conjunctivitis | FAERS: 1 | US FAERS | |
| 172 | Contraindicated product administered | FAERS: 1 | US FAERS | |
| 173 | Crying | FAERS: 1 | US FAERS | |
| 174 | Cyanosis | FAERS: 1 | US FAERS | |
| 175 | Cystitis | FAERS: 1 | US FAERS | |
| 176 | Dependence | FAERS: 1 | US FAERS | |
| 177 | Diverticulitis | FAERS: 1 | US FAERS | |
| 178 | Diverticulum | FAERS: 1 | US FAERS | |
| 179 | Drug abuse | FAERS: 1 | US FAERS | |
| 180 | Drug administered to patient of inappropriate age | FAERS: 1 | US FAERS | |
| 181 | Drug level increased | FAERS: 1 | US FAERS | |
| 182 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 183 | Drug resistance | FAERS: 1 | US FAERS | |
| 184 | Dysentery | FAERS: 1 | US FAERS | |
| 185 | Dystonia | FAERS: 1 | US FAERS | |
| 186 | Ear congestion | FAERS: 1 | US FAERS | |
| 187 | Eating disorder symptom | FAERS: 1 | US FAERS | |
| 188 | Eczema | FAERS: 1 | US FAERS | |
| 189 | Electrocardiogram change | FAERS: 1 | US FAERS | |
| 190 | Epilepsy | FAERS: 1 | US FAERS | |
| 191 | Erectile dysfunction | FAERS: 1 | US FAERS | |
| 192 | Eye allergy | FAERS: 1 | US FAERS | |
| 193 | Facial Pain | FAERS: 1 | US FAERS | |
| 194 | Flatulence | FAERS: 1 | US FAERS | |
| 195 | Flushing | FAERS: 1 | US FAERS | |
| 196 | Food Poisoning | FAERS: 1 | US FAERS | |
| 197 | Gastrointestinal Pain | FAERS: 1 | US FAERS | |
| 198 | Gastrointestinal motility disorder | FAERS: 1 | US FAERS | |
| 199 | Glaucoma | FAERS: 1 | US FAERS | |
| 200 | Hearing disability | FAERS: 1 | US FAERS | |
| 201 | Hepatitis | FAERS: 1 | US FAERS | |
| 202 | Hypertensive crisis | FAERS: 1 | US FAERS | |
| 203 | Hyperthyroidism | FAERS: 1 | US FAERS | |
| 204 | Hyperventilation | FAERS: 1 | US FAERS | |
| 205 | Hypophagia | FAERS: 1 | US FAERS | |
| 206 | Idiopathic Pulmonary Fibrosis | FAERS: 1 | US FAERS | |
| 207 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 208 | Impatience | FAERS: 1 | US FAERS | |
| 209 | Inability to afford medication | FAERS: 1 | US FAERS | |
| 210 | Inappropriate schedule of product administration | FAERS: 1 | US FAERS | |
| 211 | Incoherent | FAERS: 1 | US FAERS | |
| 212 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 213 | Incorrect drug administration rate | FAERS: 1 | US FAERS | |
| 214 | Incorrect drug dosage form administered | FAERS: 1 | US FAERS | |
| 215 | Incorrect product storage | FAERS: 1 | US FAERS | |
| 216 | Increased upper airway secretion | FAERS: 1 | US FAERS | |
| 217 | Influenza | FAERS: 1 | US FAERS | |
| 218 | Initial insomnia | FAERS: 1 | US FAERS | |
| 219 | Intercepted drug administration error | FAERS: 1 | US FAERS | |
| 220 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 221 | Irritable Bowel Syndrome | FAERS: 1 | US FAERS | |
| 222 | Joint injury | FAERS: 1 | US FAERS | |
| 223 | Laryngitis | FAERS: 1 | US FAERS | |
| 224 | Laryngospasm | FAERS: 1 | US FAERS | |
| 225 | Lip swelling | FAERS: 1 | US FAERS | |
| 226 | Local reaction | FAERS: 1 | US FAERS | |
| 227 | Loss of personal independence in daily activities | FAERS: 1 | US FAERS | |
| 228 | Magnesium Deficiency | FAERS: 1 | US FAERS | |
| 229 | Memory impairment | FAERS: 1 | US FAERS | |
| 230 | Middle insomnia | FAERS: 1 | US FAERS | |
| 231 | Migraine with Aura | FAERS: 1 | US FAERS | |
| 232 | Mood swings | FAERS: 1 | US FAERS | |
| 233 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 234 | Musculoskeletal chest pain | FAERS: 1 | US FAERS | |
| 235 | Musculoskeletal discomfort | FAERS: 1 | US FAERS | |
| 236 | Mydriasis | FAERS: 1 | US FAERS | |
| 237 | No adverse reaction | FAERS: 1 | US FAERS | |
| 238 | Nocturia | FAERS: 1 | US FAERS | |
| 239 | Nodule | FAERS: 1 | US FAERS | |
| 240 | Nonspecific reaction | FAERS: 1 | US FAERS | |
| 241 | Nystagmus | FAERS: 1 | US FAERS | |
| 242 | Ocular discomfort | FAERS: 1 | US FAERS | |
| 243 | Ovarian cancer stage III | FAERS: 1 | US FAERS | |
| 244 | Pallor | FAERS: 1 | US FAERS | |
| 245 | Pelvic Pain | FAERS: 1 | US FAERS | |
| 246 | Perforated ulcer | FAERS: 1 | US FAERS | |
| 247 | Personality Change | FAERS: 1 | US FAERS | |
| 248 | Photophobia | FAERS: 1 | US FAERS | |
| 249 | Poor quality drug administered | FAERS: 1 | US FAERS | |
| 250 | Pregnancy | FAERS: 1 | US FAERS | |
| 251 | Premenstrual Dysphoric Disorder | FAERS: 1 | US FAERS | |
| 252 | Product complaint | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 253 | Product dispensing error | FAERS: 1 | US FAERS | |
| 254 | Product outer packaging issue | FAERS: 1 | US FAERS | |
| 255 | Product packaging quantity issue | FAERS: 1 | US FAERS | |
| 256 | Product shape issue | FAERS: 1 | US FAERS | |
| 257 | Product substitution issue | FAERS: 1 | US FAERS | |
| 258 | Productive Cough | FAERS: 1 | US FAERS | |
| 259 | Punctate keratitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 260 | Rash erythematous | FAERS: 1 | US FAERS | |
| 261 | Rebound effect | FAERS: 1 | US FAERS | |
| 262 | Respiratory tract congestion | FAERS: 1 | US FAERS | |
| 263 | Restless Legs Syndrome | FAERS: 1 | US FAERS | |
| 264 | Rhinalgia | FAERS: 1 | US FAERS | |
| 265 | Rosacea | FAERS: 1 | US FAERS | |
| 266 | Shock | FAERS: 1 | US FAERS | |
| 267 | Somnambulism | FAERS: 1 | US FAERS | |
| 268 | Spinal fusion surgery | FAERS: 1 | US FAERS | |
| 269 | Stool analysis abnormal | FAERS: 1 | US FAERS | |
| 270 | Stress | FAERS: 1 | US FAERS | |
| 271 | Tachyphrenia | FAERS: 1 | US FAERS | |
| 272 | Tachyphylaxis | FAERS: 1 | US FAERS | |
| 273 | Tension | FAERS: 1 | US FAERS | |
| 274 | Therapeutic response changed | FAERS: 1 | US FAERS | |
| 275 | Therapeutic response delayed | FAERS: 1 | US FAERS | |
| 276 | Thirst | FAERS: 1 | US FAERS | |
| 277 | Urethral Obstruction | FAERS: 1 | US FAERS | |
| 278 | Urinary Incontinence | FAERS: 1 | US FAERS | |
| 279 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 280 | Urine amphetamine positive | FAERS: 1 | US FAERS | |
| 281 | Urine output increased | FAERS: 1 | US FAERS | |
| 282 | Uvulitis | FAERS: 1 | US FAERS | |
| 283 | Vitreous floaters | FAERS: 1 | US FAERS | |
| 284 | Yawning | FAERS: 1 | US FAERS | |
| 285 | Chills | Canada Vigilance: 1 | Canada Vigilance | |
| 286 | Malabsorption | Canada Vigilance: 1 | Canada Vigilance |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.