MetaADEDB 2.0 @ LMMD
Clobetasol
(FCSHDIVRCWTZOX-DVTGEIKXSA-N)
Structure
SMILES
ClCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F
Type(s)
Approved; Experimental; Investigational
ATC code(s)
D07AD01; D07CD01
Molecular Formula:
C22H28ClFO4
Molecular Weight:
410.907
Log P:
3.1422
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
74.6
CAS Number(s):
25122-41-2
Synonym(s)
1.
Clobetasol
2.
Clobetasol 17-Propionate
3.
Clobetasol Propionate
4.
Clobex
5.
Clofenazon
6.
Cormax
7.
Dermovate
8.
Embeline
9.
Embeline E
10.
OLUX
11.
Temovate
12.
Clobetasol 17 Propionate
External Link(s)
MeSHD002990
PubChem Compound5311051
ChEBI205919
CHEMBLCHEMBL1201362
DrugBankDB11750
KEGGdr:D07715
ZINC26892643
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 13
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
2Intentional product misuseFAERS: 4US FAERS
3Product quality issueFAERS: 4US FAERS
4DizzinessFAERS: 3SIDER
US FAERS
5Hypothalamic pituitary adrenal axis suppressionFAERS: 3US FAERS
6PainFAERS: 3SIDER
US FAERS
7Product use issueFAERS: 3US FAERS
8PruritusFAERS: 3SIDER
US FAERS
9AlopeciaFAERS: 2OFFSIDES
SIDER
US FAERS
10Application site painFAERS: 2OFFSIDES
SIDER
US FAERS
11AstheniaFAERS: 2US FAERS
12BlindnessFAERS: 2US FAERS
13CataractFAERS: 2OFFSIDES
US FAERS
14Drug administered to patient of inappropriate ageFAERS: 2US FAERS
15EczemaFAERS: 2US FAERS
16FatigueFAERS: 2OFFSIDES
US FAERS
17HypersensitivityFAERS: 2SIDER
US FAERS
18Hypertensive EncephalopathyFAERS: 2US FAERS
19Left Ventricular HypertrophyFAERS: 2US FAERS
20Product use in unapproved indicationFAERS: 2US FAERS
21PsoriasisFAERS: 215499763CTD
OFFSIDES
SIDER
US FAERS
22Steroid withdrawal syndromeFAERS: 2US FAERS
23AcneFAERS: 1US FAERS
24Acute kidney injuryFAERS: 1US FAERS
25AgeusiaFAERS: 1US FAERS
26AmnesiaFAERS: 1US FAERS
27AnorgasmiaFAERS: 1US FAERS
28Application site drynessFAERS: 1SIDER
US FAERS
29BedriddenFAERS: 1US FAERS
30Body fat disorderFAERS: 1US FAERS
31Burning sensationFAERS: 1SIDER
US FAERS
32CardiotoxicityFAERS: 1US FAERS
33Cerebral atrophyFAERS: 1US FAERS
34CyanosisFAERS: 1US FAERS
35Delayed myelinationFAERS: 1US FAERS
36Depressed moodFAERS: 1OFFSIDES
US FAERS
37Diabetes MellitusFAERS: 1US FAERS
38Disturbance in sexual arousalFAERS: 1US FAERS
39Drug DependenceFAERS: 1US FAERS
40Drug abuserFAERS: 1US FAERS
41Drug abuseFAERS: 1US FAERS
42Drug dispensing errorFAERS: 1US FAERS
43Drug dose omissionFAERS: 1US FAERS
44Dry skinFAERS: 1OFFSIDES
SIDER
US FAERS
45EcchymosisFAERS: 1US FAERS
46ErythemaFAERS: 1OFFSIDES
SIDER
US FAERS
47FlushingFAERS: 1US FAERS
48Genital burning sensationFAERS: 1US FAERS
49Genital painFAERS: 1US FAERS
50Genital swellingFAERS: 1US FAERS
51HeadacheFAERS: 1SIDER
US FAERS
52HirsutismFAERS: 1US FAERS
53HyperventilationFAERS: 1US FAERS
54Inappropriate schedule of drug administrationFAERS: 1US FAERS
55Incorrect drug administration durationFAERS: 1US FAERS
56Increased tendency to bruiseFAERS: 1US FAERS
57Intentional product use issueFAERS: 1US FAERS
58Lip and/or oral cavity cancerFAERS: 1US FAERS
59LipohypertrophyFAERS: 1OFFSIDES
US FAERS
60NauseaFAERS: 1SIDER
US FAERS
61No adverse eventFAERS: 1US FAERS
62OsteopeniaFAERS: 1US FAERS
63Pericardial effusionFAERS: 1US FAERS
64Prescription drug used without a prescriptionFAERS: 1US FAERS
65Primary hypogonadismFAERS: 1US FAERS
66Product container issueFAERS: 1US FAERS
67Product expiration date issueFAERS: 1US FAERS
68Product preparation errorFAERS: 1US FAERS
69Product storage errorFAERS: 1US FAERS
70Product substitution issueFAERS: 1US FAERS
71Product taste abnormalFAERS: 1US FAERS
72ScabFAERS: 1US FAERS
73Sexual DysfunctionFAERS: 1US FAERS
74Skin PapillomaFAERS: 1US FAERS
75Skin UlcerFAERS: 1US FAERS
76SyncopeFAERS: 1US FAERS
77TremorFAERS: 1US FAERS
78TrichorrhexisFAERS: 1US FAERS
79UlcerFAERS: 1OFFSIDES
US FAERS
80Unevaluable eventFAERS: 1US FAERS
81Vitamin D DeficiencyFAERS: 1US FAERS
82Wrong technique in product usage processFAERS: 1US FAERS
83treatment failureFAERS: 1US FAERS
84Abdominal PainOFFSIDES
85Abdominal discomfortOFFSIDES
86Abdominal rigidityOFFSIDES
87Abnormal visionOFFSIDES
88Acute bronchitisOFFSIDES
89Acute myocardial infarctionOFFSIDES
90Acute respiratory failureOFFSIDES
91AdenitisOFFSIDES
92AngerOFFSIDES
93AnhidrosisOFFSIDES
94AnorexiaOFFSIDES
95AnxietyOFFSIDES
96ApneaOFFSIDES
97AppendectomyOFFSIDES
98Application site atrophySIDER
99Application site burnSIDER
100Application site irritationSIDER
101Application site pigmentation changesSIDER
102Application site pruritusSIDER
103Application site reactionSIDER
104ArteriosclerosisOFFSIDES
105ArthritisOFFSIDES
106ArthropathyOFFSIDES
107Aspiration PneumoniaOFFSIDES
108AtelectasisOFFSIDES
109AtherosclerosisOFFSIDES
110AtopySIDER
111AuraOFFSIDES
112Autoimmune hepatitisOFFSIDES
113BlepharospasmOFFSIDES
114Blood cholesterol abnormalOFFSIDES
115Blood lactate dehydrogenase increasedOFFSIDES
116Blood triglycerides increasedOFFSIDES
117Blood uric acidOFFSIDES
118Blurred visionOFFSIDES
119Bone scan abnormalOFFSIDES
120BradycardiaOFFSIDES
121BronchiolitisOFFSIDES
122BronchopneumoniaOFFSIDES
123Bronchopulmonary DysplasiaOFFSIDES
124BruxismOFFSIDES
125Bunion operationOFFSIDES
126BunionOFFSIDES
127Candidiasis of vaginaOFFSIDES
128CellulitisOFFSIDES
129Cerebral artery occlusionOFFSIDES
130Cervicobrachial syndromeOFFSIDES
131Chest PainOFFSIDES
132Choking sensationOFFSIDES
133Chronic Obstructive Airway DiseaseOFFSIDES
134Compression fractureOFFSIDES
135ConfabulationOFFSIDES
136Congenital tricuspid valve incompetenceOFFSIDES
137CyanopsiaOFFSIDES
138DehydrationOFFSIDES
139DemyelinationOFFSIDES
140Dermatitis acneiformSIDER
141Dermatitis, Irritant11851881CTD
142DermatitisSIDER
143Device FailureOFFSIDES
144Device leakageOFFSIDES
145Device related infectionOFFSIDES
146DiabetesOFFSIDES
147Diabetic FootOFFSIDES
148DiarrheaOFFSIDES
149Diastolic dysfunctionOFFSIDES
150DiplopiaOFFSIDES
151DiscomfortSIDER
152DiverticulumOFFSIDES
153Drug administration errorOFFSIDES
154Drug exposure during pregnancyOFFSIDES
155Drug toxicityOFFSIDES
156DysmorphismOFFSIDES
157DyspareuniaOFFSIDES
158DysuriaOFFSIDES
159Economic problemOFFSIDES
160Emotional distressOFFSIDES
161Erectile dysfunctionOFFSIDES
162ExcoriationSIDER
163Extremity contractureOFFSIDES
164Eye irritationSIDER
165Eye painOFFSIDES
SIDER
166Face LiftOFFSIDES
167Facial wastingOFFSIDES
168Failure to ThriveOFFSIDES
169Febrile NeutropeniaOFFSIDES
170Feelings of worthlessnessOFFSIDES
171Flank PainOFFSIDES
172Folliculitis1671328CTD
SIDER
173GamblingOFFSIDES
174GlycosuriaSIDER
175GoutOFFSIDES
176GranulomaOFFSIDES
177Hepatic InfectionOFFSIDES
178Hepatitis B positiveOFFSIDES
179HomicideOFFSIDES
180HydrocephalusOFFSIDES
181Hyperglycemia19422381CTD
182HypertrichosisSIDER
183HypophagiaOFFSIDES
184IncontinenceOFFSIDES
185IndurationSIDER
186InfectionOFFSIDES
SIDER
187Infective spondylitisOFFSIDES
188InfestationSIDER
189InfluenzaSIDER
190Instillation site painSIDER
191Intervertebral Disc DegenerationOFFSIDES
192LeukodermaSIDER
193Lichen Planus15284791CTD
194LichenificationSIDER
195Limb injuryOFFSIDES
196Loose toothOFFSIDES
197LymphedemaOFFSIDES
198LymphocytosisOFFSIDES
199Mental impairmentOFFSIDES
200Mental status changesOFFSIDES
201MesotheliomaOFFSIDES
202MiliariaSIDER
203Muscle necrosisOFFSIDES
204Musculoskeletal chest painOFFSIDES
205Mycosis FungoidesOFFSIDES
206Nail InfectionOFFSIDES
207NasopharyngitisSIDER
208Nephrogenic Fibrosing DermopathyOFFSIDES
209NeurodermatitisOFFSIDES
210NoduleOFFSIDES
211OsteomyelitisOFFSIDES
212OsteoporosisOFFSIDES
213OsteosclerosisOFFSIDES
214Pain of skinSIDER
215PancreatitisOFFSIDES
216PeriodontitisOFFSIDES
217PneumothoraxOFFSIDES
218Polysubstance abuseOFFSIDES
219Psoriasis flare-upSIDER
220Psychiatric symptomOFFSIDES
221Pulmonary HypertensionOFFSIDES
222PurpuraSIDER
223Pustular psoriasisOFFSIDES
224PyodermaSIDER
225QRS axis abnormalOFFSIDES
226Respiratory FailureOFFSIDES
227Retinopathy of PrematurityOFFSIDES
228RosaceaSIDER
229SclerodermaOFFSIDES
230SequestrectomyOFFSIDES
231Sinus operationOFFSIDES
232SinusitisOFFSIDES
233Skin Abnormalities18246695CTD
234Skin IndurationOFFSIDES
235Skin discomfortSIDER
236Skin hypertrophySIDER
237Skin irritationSIDER
238Skin tightnessSIDER
239Spinal column stenosisOFFSIDES
240Spinal fusion surgeryOFFSIDES
241Squamous cell carcinoma of skinOFFSIDES
242Synovial CystOFFSIDES
243Telangiectasis3888708CTD
244TenosynovitisOFFSIDES
245ThrombophlebitisOFFSIDES
246TinnitusOFFSIDES
247Tooth ExtractionOFFSIDES
248Transaminases increasedOFFSIDES
249Trisomy 21OFFSIDES
250UrticariaSIDER
251Vaginal Diseases15284791CTD
252Vascular purpuraSIDER
253Venous InsufficiencyOFFSIDES
254VertebroplastyOFFSIDES
255Violence-related symptomOFFSIDES
256Vitiligo9762827CTD
257Vulvar Diseases15284791CTD
258Weight GainOFFSIDES
259pustuleSIDER
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