MetaADEDB 2.0 @ LMMD
Etretinate
(HQMNCQVAMBCHCO-DJRRULDNSA-N)
Structure
SMILES
CCOC(=O)/C=C(/C=C/C=C(/C=C/c1c(C)cc(c(c1C)C)OC)\C)\C
Type(s)
Withdrawn
ATC code(s)
D05BB01
Molecular Formula:
C23H30O3
Molecular Weight:
354.482
Log P:
5.6455
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
35.53
CAS Number(s):
54350-48-0; 69427-41-4
Synonym(s)
1.
Etretinate
2.
B10-9359
3.
Ethyl Etrinoate
4.
Ro 10-9359
5.
Ro-10-9359
6.
Tigason
7.
Tigazon
8.
B10 9359
9.
B109359
10.
Etrinoate, Ethyl
11.
Ro 10 9359
12.
Ro 109359
13.
Ro109359
External Link(s)
MeSHD005050
PubChem Compound5282375
3312
BindingDB50248000
ChEBI94591
4913
CHEMBLCHEMBL464
DrugBankDB00926
DrugCentral1116
IUPHAR/BPS Guide to PHARMACOLOGY7599
KEGGdr:D00316
Therapeutic Target DatabaseD0B1IP
ZINC3830820
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AstheniaFAERS: 1US FAERS
2Gastric ulcerFAERS: 1US FAERS
3HeadacheFAERS: 16138537CTD
US FAERS
4NauseaFAERS: 1US FAERS
5PainFAERS: 1US FAERS
6SepsisFAERS: 1US FAERS
7VomitingFAERS: 1US FAERS
8Weight decreasedFAERS: 1US FAERS
9Abnormalities, Drug-Induced2114463CTD
10Acute kidney injury1477420CTD
11ArthralgiaCanada Vigilance: 18277044CTD
Canada Vigilance
12Chemical and Drug Induced Liver Injury, Chronic11922592CTD
13Craniofacial Abnormalities9021329
9200351		CTD
14Depressive disorder2497882CTD
15Erectile dysfunction1998382CTD
16Facial paralysisCanada Vigilance: 1Canada Vigilance
17Fibrosis11922592CTD
18Hepatitis1938411
2413699
16882189		CTD
19Hypercalcemia6150159CTD
20Hyperlipoproteinemias3721869CTD
21Intracranial Hypertension6138537CTD
22Jaundice, Obstructive4078057CTD
23Liver Cirrhosis11922592CTD
24Maxillofacial Abnormalities2114463CTD
25Muscle Hypertonia3711400CTD
26Muscle Rigidity3173366CTD
27MyalgiaCanada Vigilance: 1Canada Vigilance
28Mycosis Fungoides4056125CTD
29Pityriasis Rubra Pilaris1477420CTD
30Psoriasis

View details

1998382
2413699
2497882
2954577
3173366
3711400
3888246
8277044
8381828
11922592
 		CTD
31Retinal depositsCanada Vigilance: 1Canada Vigilance
32Rosacea6183905CTD
33UrticariaCanada Vigilance: 1Canada Vigilance
34jaundice3652901CTD
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