MetaADEDB 2.0 @ LMMD
Methadone
(USSIQXCVUWKGNF-UHFFFAOYSA-N)
Structure
SMILES
CCC(=O)C(c1ccccc1)(c1ccccc1)CC(N(C)C)C
Type(s)
Approved; Illicit
ATC code(s)
N02AC52; N07BC02
Molecular Formula:
C21H27NO
Molecular Weight:
309.445
Log P:
4.2920
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
20.31
CAS Number(s):
76-99-3; 5967-73-7
Synonym(s)
1.
Methadone
2.
Amidone
3.
Biodone
4.
Dolophine
5.
Metadol
6.
Metasedin
7.
Methaddict
8.
Methadone Hydrochloride
9.
Methadose
10.
Methex
11.
Phenadone
12.
Phymet
13.
Physeptone
14.
Pinadone
15.
Symoron
16.
Hydrochloride, Methadone
External Link(s)
MeSHD008691
PubChem Compound4095
BindingDB50027393
82507
ChEBI6807
CHEMBLCHEMBL651
DrugBankDB00333
DrugCentral1728
IUPHAR/BPS Guide to PHARMACOLOGY5458
KEGGcpd:C07163
dr:D08195
Therapeutic Target DatabaseD09OJQ
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Toxicity to various agentsFAERS: 162
Canada Vigilance: 5		Canada Vigilance
US FAERS
2OverdoseFAERS: 106
Canada Vigilance: 6		Canada Vigilance
OFFSIDES
US FAERS
3Drug ineffectiveFAERS: 52OFFSIDES
US FAERS
4Respiratory DepressionFAERS: 43
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
5SomnolenceFAERS: 39
Canada Vigilance: 5		Canada Vigilance
SIDER
US FAERS
6Cardiac ArrestFAERS: 36
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
7Unresponsive to stimuliFAERS: 35
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
8StrabismusFAERS: 33US FAERS
9Product quality issueFAERS: 32US FAERS
10Depressed Level of ConsciousnessFAERS: 31
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
11MalaiseFAERS: 29US FAERS
12Accidental overdoseFAERS: 27
Canada Vigilance: 3		Canada Vigilance
US FAERS
13NauseaFAERS: 27
Canada Vigilance: 2		15972261CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
14Accidental exposure to product by childFAERS: 26
Canada Vigilance: 2		Canada Vigilance
US FAERS
15Drug abuseFAERS: 26
Canada Vigilance: 1		Canada Vigilance
US FAERS
16HypotensionFAERS: 26
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
17Completed SuicideFAERS: 25US FAERS
18Respiratory arrestFAERS: 25
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
19VomitingFAERS: 22
Canada Vigilance: 1		15454842CTD
SIDER
Canada Vigilance
US FAERS
20Drug diversionFAERS: 20US FAERS
21PoisoningFAERS: 1921439157CTD
US FAERS
22HeadacheFAERS: 18
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
23LeukoencephalopathyFAERS: 18OFFSIDES
US FAERS
24Respiratory FailureFAERS: 17
Canada Vigilance: 1		Canada Vigilance
US FAERS
25Drug withdrawal syndromeFAERS: 16SIDER
US FAERS
26DeliriumFAERS: 15
Canada Vigilance: 1		11303498
17906213		CTD
Canada Vigilance
US FAERS
27Mental status changesFAERS: 15OFFSIDES
US FAERS
28Respiratory distressFAERS: 15US FAERS
29ConstipationFAERS: 138874346CTD
SIDER
US FAERS
30Exposure during breast feedingFAERS: 13US FAERS
31Feeling abnormalFAERS: 13
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
32HypoxiaFAERS: 1316997682
19819313		CTD
OFFSIDES
US FAERS
33Intentional drug misuseFAERS: 13US FAERS
34LethargyFAERS: 13OFFSIDES
US FAERS
35PneumoniaFAERS: 13US FAERS
36NystagmusFAERS: 12OFFSIDES
US FAERS
37PainFAERS: 12

View details

2886842
4028630
7486124
7562497
7892029
8874346
11145498
11303498
11406880
11744587
11783819
12230351
15454842
15471646
15795907
15810761
15857742
15972261
16238992
16877186
17319250
17378505
17394991
17480178
17906213
18715174
19317728
19437394
19824814
 		CTD
OFFSIDES
SIDER
US FAERS
38TremorFAERS: 1211783819CTD
SIDER
US FAERS
39DizzinessFAERS: 11
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
40RhabdomyolysisFAERS: 11
Canada Vigilance: 1		1436354
19392810		CTD
Canada Vigilance
US FAERS
41Accidental exposure to productFAERS: 10
Canada Vigilance: 1		Canada Vigilance
US FAERS
42Acute kidney injuryFAERS: 101436354
4936579		CTD
US FAERS
43Biliary dilatationFAERS: 10US FAERS
44CyanosisFAERS: 101436354
16997682		CTD
US FAERS
45Posterior reversible encephalopathy syndromeFAERS: 10US FAERS
46Vision abnormal neonatalFAERS: 10US FAERS
47AgitationFAERS: 9
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
48EncephalitisFAERS: 9US FAERS
49SyncopeFAERS: 9
Canada Vigilance: 2

View details

14556883
16865634
17344330
18686025
 		CTD
SIDER
Canada Vigilance
US FAERS
50BradycardiaFAERS: 8

View details

4743335
12222559
15961013
16395081
 		CTD
SIDER
US FAERS
51Incorrect dose administeredFAERS: 8US FAERS
52Medication ErrorFAERS: 8US FAERS
53Suicide attemptFAERS: 8US FAERS
54AstheniaFAERS: 7
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
55Drug DependenceFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
56Drug level increasedFAERS: 7US FAERS
57Intentional product misuseFAERS: 7US FAERS
58Product substitution issueFAERS: 7US FAERS
59PruritusFAERS: 7
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
60Toxic leukoencephalopathyFAERS: 7US FAERS
61Acute respiratory failureFAERS: 6US FAERS
62AstigmatismFAERS: 6US FAERS
63FatigueFAERS: 6
Canada Vigilance: 3		Canada Vigilance
OFFSIDES
US FAERS
64HydrocephalusFAERS: 616997682CTD
US FAERS
65Metabolic acidosisFAERS: 6US FAERS
66SepsisFAERS: 6US FAERS
67TachycardiaFAERS: 6SIDER
US FAERS
68Weight decreasedFAERS: 6SIDER
US FAERS
69Abdominal PainFAERS: 5
Canada Vigilance: 1		11506132CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
70DehydrationFAERS: 52554359CTD
OFFSIDES
US FAERS
71Drug dispensing errorFAERS: 5US FAERS
72Drug screen negativeFAERS: 5OFFSIDES
US FAERS
73Drug screen positiveFAERS: 5OFFSIDES
US FAERS
74HypoventilationFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
75IntussusceptionFAERS: 5US FAERS
76LeukocytosisFAERS: 5US FAERS
77Memory impairmentFAERS: 5US FAERS
78Muscle SpasticityFAERS: 5US FAERS
79Product taste abnormalFAERS: 5US FAERS
80RestlessnessFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
81Urinary IncontinenceFAERS: 5US FAERS
82AnxietyFAERS: 4
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
83ArthralgiaFAERS: 4US FAERS
84Brain DeathFAERS: 4US FAERS
85Chest PainFAERS: 4
Canada Vigilance: 2		Canada Vigilance
US FAERS
86Drug administration errorFAERS: 4US FAERS
87Drug prescribing errorFAERS: 4US FAERS
88Drug toxicityFAERS: 4OFFSIDES
US FAERS
89Erectile dysfunctionFAERS: 4
Canada Vigilance: 1		4474860
18093096		CTD
OFFSIDES
Canada Vigilance
US FAERS
90Exposure via breast milkFAERS: 4US FAERS
91HomicideFAERS: 4US FAERS
92HyperreflexiaFAERS: 4US FAERS
93MyalgiaFAERS: 4US FAERS
94Narcotic Bowel SyndromeFAERS: 4US FAERS
95PalpitationsFAERS: 4
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
96PetechiaeFAERS: 4US FAERS
97PriapismFAERS: 4US FAERS
98PurpuraFAERS: 4US FAERS
99Accidental exposureFAERS: 3US FAERS
100AlopeciaFAERS: 3US FAERS
101Altered state of consciousnessFAERS: 3US FAERS
102AmnesiaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
103AtaxiaFAERS: 319808992CTD
OFFSIDES
US FAERS
104BlindnessFAERS: 34367894CTD
US FAERS
105Blood immunoglobulin G increasedFAERS: 3OFFSIDES
US FAERS
106CardiotoxicityFAERS: 3US FAERS
107CatatoniaFAERS: 3US FAERS
108Cerebellar infarctionFAERS: 3US FAERS
109Congenital nystagmusFAERS: 3US FAERS
110DeafnessFAERS: 3
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
111Disease ProgressionFAERS: 3OFFSIDES
US FAERS
112Drug abuserFAERS: 3OFFSIDES
US FAERS
113Drug dose omissionFAERS: 3OFFSIDES
US FAERS
114HeterophoriaFAERS: 3US FAERS
115HypersensitivityFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
116Intestinal ObstructionFAERS: 3US FAERS
117Libido disorderFAERS: 3US FAERS
118NarcolepsyFAERS: 3US FAERS
119NeuralgiaFAERS: 3US FAERS
120Product dispensing errorFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
121Pulmonary HypertensionFAERS: 3US FAERS
122Sinus TachycardiaFAERS: 3US FAERS
123Therapeutic response unexpectedFAERS: 3US FAERS
124ThrombocytopeniaFAERS: 3SIDER
US FAERS
125Ventricular FibrillationFAERS: 3SIDER
US FAERS
126Abnormal organ growthFAERS: 2US FAERS
127Activities of daily living impairedFAERS: 2US FAERS
128Acute Coronary SyndromeFAERS: 2US FAERS
129Acute Lung InjuryFAERS: 2US FAERS
130Alanine Aminotransferase IncreasedFAERS: 2US FAERS
131Anion GapFAERS: 2US FAERS
132AphasiaFAERS: 2US FAERS
133Apparent deathFAERS: 2US FAERS
134Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
135AsphyxiaFAERS: 2US FAERS
136AsthenopiaFAERS: 2US FAERS
137Atrial FibrillationFAERS: 2US FAERS
138BedriddenFAERS: 2US FAERS
139Blood alkaline phosphatase increasedFAERS: 2US FAERS
140Blood creatinine increasedFAERS: 2US FAERS
141Blood glucose decreasedFAERS: 2US FAERS
142Blood glucose increasedFAERS: 2US FAERS
143Blood urea increasedFAERS: 2US FAERS
144BronchitisFAERS: 2OFFSIDES
US FAERS
145Burning sensationFAERS: 2OFFSIDES
US FAERS
146Cerebrovascular accidentFAERS: 2US FAERS
147Chest discomfortFAERS: 2US FAERS
148Dental cariesFAERS: 217687962CTD
OFFSIDES
US FAERS
149Diabetes InsipidusFAERS: 2US FAERS
150DiscomfortFAERS: 2US FAERS
151DisorientationFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
152Drug level decreasedFAERS: 2US FAERS
153Drug withdrawal headacheFAERS: 2OFFSIDES
US FAERS
154DysarthriaFAERS: 2US FAERS
155DyspepsiaFAERS: 2US FAERS
156DysphoniaFAERS: 2US FAERS
157Emotional distressFAERS: 2OFFSIDES
US FAERS
158EpidermolysisFAERS: 2US FAERS
159Executive dysfunctionFAERS: 2US FAERS
160FlushingFAERS: 2
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
161Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
162Gastrointestinal motility disorderFAERS: 2OFFSIDES
US FAERS
163GliosisFAERS: 2US FAERS
164HemiparesisFAERS: 2US FAERS
165HepatotoxicityFAERS: 2US FAERS
166HypercapniaFAERS: 219819313CTD
US FAERS
167HypersomniaFAERS: 2US FAERS
168HypokinesiaFAERS: 2US FAERS
169Impaired driving abilityFAERS: 2US FAERS
170IncontinenceFAERS: 2US FAERS
171Incorrect route of drug administrationFAERS: 2US FAERS
172Incorrect route of product administrationFAERS: 2US FAERS
173Intentional product use issueFAERS: 2US FAERS
174Liquid product physical issueFAERS: 2US FAERS
175Maternal exposure during pregnancyFAERS: 2US FAERS
176Multi-organ disorderFAERS: 2US FAERS
177Muscle tightnessFAERS: 2US FAERS
178Musculoskeletal PainFAERS: 2OFFSIDES
US FAERS
179MydriasisFAERS: 2SIDER
US FAERS
180Myocardial InfarctionFAERS: 215477802CTD
US FAERS
181NecrosisFAERS: 24586767
16931994
20691259		CTD
US FAERS
182Neurological decompensationFAERS: 2US FAERS
183ParanoiaFAERS: 2OFFSIDES
US FAERS
184Placenta AccretaFAERS: 2US FAERS
185Placental InsufficiencyFAERS: 2US FAERS
186Prescription drug used without a prescriptionFAERS: 2US FAERS
187Product counterfeitFAERS: 2US FAERS
188Product tamperingFAERS: 2US FAERS
189Product use in unapproved indicationFAERS: 2US FAERS
190Product use issueFAERS: 2US FAERS
191QuadriparesisFAERS: 2US FAERS
192Rash erythematousFAERS: 2US FAERS
193SneezingFAERS: 2SIDER
US FAERS
194StillbirthFAERS: 2US FAERS
195StridorFAERS: 2US FAERS
196Sudden infant death syndromeFAERS: 2US FAERS
197TachyarrhythmiaFAERS: 2US FAERS
198Transaminases increasedFAERS: 2US FAERS
199Unevaluable eventFAERS: 2US FAERS
200UrticariaFAERS: 2SIDER
US FAERS
201Visual ImpairmentFAERS: 2SIDER
US FAERS
202Wrong technique in drug usage processFAERS: 2OFFSIDES
US FAERS
203nervous system disorderFAERS: 2US FAERS
204AbasiaFAERS: 1US FAERS
205Abdominal tendernessFAERS: 1US FAERS
206Alcohol poisoningFAERS: 1US FAERS
207AngerFAERS: 1US FAERS
208AnoxiaFAERS: 1US FAERS
209AntimetropiaFAERS: 1US FAERS
210Apallic syndromeFAERS: 1US FAERS
211ApathyFAERS: 1US FAERS
212Aplasia Cutis CongenitaFAERS: 1US FAERS
213ArteriosclerosisFAERS: 1OFFSIDES
US FAERS
214AtelectasisFAERS: 1OFFSIDES
US FAERS
215AutomatismFAERS: 1US FAERS
216Back PainFAERS: 116089243
19996237		CTD
US FAERS
217Biopsy chorionic villous abnormalFAERS: 1US FAERS
218Blood thyroid stimulating hormone increasedFAERS: 1US FAERS
219BradyphreniaFAERS: 1US FAERS
220Brain HypoxiaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
221Breath HoldingFAERS: 1US FAERS
222BronchiectasisFAERS: 1US FAERS
223BronchopneumoniaFAERS: 1US FAERS
224BruxismFAERS: 1US FAERS
225CardiomegalyFAERS: 1US FAERS
226Cauda Equina SyndromeFAERS: 1US FAERS
227CellulitisFAERS: 1OFFSIDES
US FAERS
228Cerebral atrophyFAERS: 1US FAERS
229ChillsFAERS: 1SIDER
US FAERS
230Choking sensationFAERS: 1OFFSIDES
US FAERS
231ChokingFAERS: 1OFFSIDES
US FAERS
232Cleft PalateFAERS: 1US FAERS
233ClonusFAERS: 1US FAERS
234Cold sweatFAERS: 1US FAERS
235Consciousness fluctuatingFAERS: 1US FAERS
236Contraindicated drug administeredFAERS: 1US FAERS
237Cortisol decreasedFAERS: 1US FAERS
238Croup infectiousFAERS: 1US FAERS
239CryingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
240Cryoglobulins presentFAERS: 1US FAERS
241Deafness NeurosensoryFAERS: 1US FAERS
242DementiaFAERS: 1US FAERS
243Disseminated Intravascular CoagulationFAERS: 1US FAERS
244Drug ToleranceFAERS: 1US FAERS
245Drug administered to patient of inappropriate ageFAERS: 1US FAERS
246Drug effect incompleteFAERS: 1US FAERS
247Drug screen false positiveFAERS: 1US FAERS
248DysgeusiaFAERS: 1OFFSIDES
US FAERS
249DyspareuniaFAERS: 1US FAERS
250DysphemiaFAERS: 1OFFSIDES
US FAERS
251DysuriaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
252EcchymosisFAERS: 1US FAERS
253Economic problemFAERS: 1US FAERS
254Ejection Fraction DecreasedFAERS: 1US FAERS
255Electrocardiogram ST-T segment abnormalFAERS: 1US FAERS
256Electrocardiogram changeFAERS: 1US FAERS
257Electroencephalogram abnormalFAERS: 1US FAERS
258EmpyemaFAERS: 1US FAERS
259EndocarditisFAERS: 1OFFSIDES
US FAERS
260Euphoric moodFAERS: 1SIDER
US FAERS
261Extra dose administeredFAERS: 1US FAERS
262Feeling ColdFAERS: 1OFFSIDES
SIDER
US FAERS
263Feeling of body temperature changeFAERS: 1US FAERS
264FormicationFAERS: 1OFFSIDES
US FAERS
265Fragile X SyndromeFAERS: 1US FAERS
266Gastrointestinal PainFAERS: 1SIDER
US FAERS
267Gaze palsyFAERS: 1US FAERS
268General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
269Growth retardationFAERS: 1US FAERS
270Hepatic congestionFAERS: 1US FAERS
271Hepatitis CFAERS: 1OFFSIDES
US FAERS
272HypervigilanceFAERS: 1US FAERS
273HypophagiaFAERS: 1US FAERS
274Hyporesponsive to stimuliFAERS: 1US FAERS
275Hypothalamo-pituitary disorderFAERS: 1US FAERS
276IleusFAERS: 1US FAERS
277Implantable defibrillator insertionFAERS: 1US FAERS
278Inadequate analgesiaFAERS: 1US FAERS
279InfectionFAERS: 1OFFSIDES
US FAERS
280InfertilityFAERS: 1US FAERS
281Injection site abscessFAERS: 1US FAERS
282Intestinal Pseudo-ObstructionFAERS: 1US FAERS
283Irregular breathingFAERS: 1US FAERS
284Joint swellingFAERS: 1US FAERS
285Left Ventricular HypertrophyFAERS: 1OFFSIDES
US FAERS
286Lip swellingFAERS: 1US FAERS
287Livedo ReticularisFAERS: 1US FAERS
288Locked-In SyndromeFAERS: 1US FAERS
289Long QT SyndromeFAERS: 1

View details

14527710
14556883
15232338
15550974
15875343
15918160
15986265
16100543
16144878
16178046
16801510
17026725
17101952
17101953
17110841
17319250
17344330
17376175
17394991
17480178
18032235
18072176
18178408
18686025
18774239
19042586
19386945
20177760
20390695
 		CTD
US FAERS
290Loss of personal independence in daily activitiesFAERS: 1US FAERS
291Low birth weight babyFAERS: 1US FAERS
292Lung consolidationFAERS: 1US FAERS
293LymphadenopathyFAERS: 1US FAERS
294LymphomaFAERS: 1US FAERS
295LymphopeniaFAERS: 1US FAERS
296Maternal exposure during breast feedingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
297Maternal exposure timing unspecifiedFAERS: 1US FAERS
298Medication dilutionFAERS: 1US FAERS
299Mental impairmentFAERS: 1US FAERS
300MicrocephalyFAERS: 1US FAERS
301Mood swingsFAERS: 1US FAERS
302Multiple drug overdose accidentalFAERS: 1US FAERS
303Muscle FatigueFAERS: 1US FAERS
304Muscle RigidityFAERS: 1US FAERS
305Musculoskeletal stiffnessFAERS: 1US FAERS
306MutismFAERS: 117187532CTD
US FAERS
307MyoclonusFAERS: 1

View details

7486124
11406880
17906213
18715174
 		CTD
US FAERS
308NasopharyngitisFAERS: 1SIDER
US FAERS
309Neck PainFAERS: 1US FAERS
310Neonatal respiratory acidosisFAERS: 1US FAERS
311Neonatal respiratory depressionFAERS: 1US FAERS
312NeurodermatitisFAERS: 1US FAERS
313NocturiaFAERS: 1US FAERS
314Noninfective gingivitisFAERS: 1US FAERS
315Oropharyngeal painFAERS: 1OFFSIDES
US FAERS
316OsteoporosisFAERS: 1OFFSIDES
SIDER
US FAERS
317PallorFAERS: 1US FAERS
318Pancreatic duct dilatationFAERS: 1US FAERS
319PancreatitisFAERS: 1OFFSIDES
US FAERS
320Patent ductus arteriosusFAERS: 1US FAERS
321Pelvic PainFAERS: 1US FAERS
322Peripheral swellingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
323Pharyngolaryngeal PainFAERS: 1US FAERS
324PneumoconiosisFAERS: 1US FAERS
325PolyuriaFAERS: 1US FAERS
326Poor weight gain neonatalFAERS: 1US FAERS
327PosturingFAERS: 1US FAERS
328Prescribed overdoseFAERS: 1US FAERS
329Product administered to patient of inappropriate ageFAERS: 1US FAERS
330Product complaintFAERS: 1US FAERS
331Product dispensing issueFAERS: 1US FAERS
332Product dose omissionFAERS: 1US FAERS
333Product label confusionFAERS: 1US FAERS
334Product storage errorFAERS: 1US FAERS
335Protein urine presentFAERS: 1US FAERS
336Pulmonary EmbolismFAERS: 1US FAERS
337Pulmonary congestionFAERS: 1US FAERS
338Pulmonary granulomaFAERS: 1US FAERS
339Purple urine bag syndromeFAERS: 1US FAERS
340RalesFAERS: 1US FAERS
341Respiratory ParalysisFAERS: 1US FAERS
342Respiratory tract congestionFAERS: 1OFFSIDES
US FAERS
343Restless Legs SyndromeFAERS: 1US FAERS
344Rhinovirus infectionFAERS: 1US FAERS
345RhonchiFAERS: 1US FAERS
346RosaceaFAERS: 1US FAERS
347Septic ShockFAERS: 1US FAERS
348Septic embolusFAERS: 1US FAERS
349Serotonin SyndromeFAERS: 117187532
19996237		CTD
US FAERS
350Sexual DysfunctionFAERS: 1US FAERS
351ShockFAERS: 1SIDER
US FAERS
352Sinus bradycardiaFAERS: 1US FAERS
353Skin lesionFAERS: 1US FAERS
354Slow response to stimuliFAERS: 1US FAERS
355SnoringFAERS: 1US FAERS
356Spontaneous penile erectionFAERS: 1US FAERS
357Staphylococcus test positiveFAERS: 1US FAERS
358Status EpilepticusFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
359StressFAERS: 1US FAERS
360Sudden Cardiac DeathFAERS: 1US FAERS
361Sudden deathFAERS: 1US FAERS
362SwellingFAERS: 1SIDER
US FAERS
363Tablet physical issueFAERS: 1US FAERS
364Teeth brittleFAERS: 1US FAERS
365Therapeutic product ineffectiveFAERS: 1US FAERS
366Therapy non-responderFAERS: 1US FAERS
367ThrombocytosisFAERS: 1US FAERS
368TinnitusFAERS: 1US FAERS
369Tooth ErosionFAERS: 1US FAERS
370Toxicologic test abnormalFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
371Transfusion-Related Acute Lung InjuryFAERS: 1US FAERS
372TrismusFAERS: 1US FAERS
373Trisomy 21FAERS: 1US FAERS
374UnderweightFAERS: 1US FAERS
375Urinary RetentionFAERS: 1SIDER
US FAERS
376VasculitisFAERS: 1US FAERS
377VertigoFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
378Viral load increasedFAERS: 1US FAERS
379Waist circumference increasedFAERS: 1US FAERS
380Wrong doseFAERS: 1US FAERS
381Wrong drug administeredFAERS: 1OFFSIDES
US FAERS
382Wrong patient received medicationFAERS: 1US FAERS
383Wrong technique in product usage processFAERS: 1US FAERS
384treatment failureFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
385Abdominal CrampsSIDER
386Abdominal discomfortCanada Vigilance: 1Canada Vigilance
OFFSIDES
387Abnormalities, Drug-Induced4586767
6178811		CTD
388AbuseOFFSIDES
389AcheSIDER
390Acid refluxOFFSIDES
391ActinomycosisOFFSIDES
392Acute psychosisOFFSIDES
393Acute sinusitisOFFSIDES
394AgraphiaOFFSIDES
395Alcohol withdrawal syndromeOFFSIDES
396AlveolitisOFFSIDES
397AlveoloplastyOFFSIDES
398AnalgesiaOFFSIDES
399Anaphylactic shockSIDER
400Anencephaly4586767CTD
401AnhedoniaOFFSIDES
402AnorexiaOFFSIDES
SIDER
403Anticonvulsant drug level above therapeuticOFFSIDES
404Apnea4936579
16997682		CTD
OFFSIDES
405ArthritisOFFSIDES
406AsthmaOFFSIDES
407Atrial tachycardiaOFFSIDES
408AuraOFFSIDES
409Back disorderOFFSIDES
410Bile Duct Diseases12838240CTD
411Bipolar DisorderOFFSIDES
412Bladder cystOFFSIDES
413Bladder neck obstructionOFFSIDES
414Blood GlucoseOFFSIDES
415Blood albumin decreasedOFFSIDES
416Blood pressure fluctuationOFFSIDES
417Blood sodium abnormalOFFSIDES
418Blood testosterone decreasedSIDER
419Blurred visionOFFSIDES
420Body TemperatureOFFSIDES
421Bone lesionOFFSIDES
422Bone painOFFSIDES
423Bone swellingOFFSIDES
424Bone trimmingOFFSIDES
425Bowel spasmSIDER
426Brain Edema16997682
19782326		CTD
427Brain natriuretic peptide increasedOFFSIDES
428Breakthrough PainOFFSIDES
429BronchospasmCanada Vigilance: 1Canada Vigilance
430Cardiovascular insufficiencySIDER
431Catalepsy987911
990037
2899450		CTD
432Central venous catheter removalOFFSIDES
433Cerebrovascular Disorders12629538CTD
434Cervical dysplasiaOFFSIDES
435Chemotherapeutic drug level increasedOFFSIDES
436Child Behavior Disorders7121694
7683453		CTD
437CholecystitisOFFSIDES
438Chorea6108101
9754849
11783819		CTD
439Chronic Obstructive Airway DiseaseOFFSIDES
440Chronic sinusitisOFFSIDES
441Chronic ulcerative colitisOFFSIDES
442Circulatory depressionSIDER
443Cocaine-Related Disorders

View details

9888118
9892294
10372794
10545663
10631964
10708326
10723850
10934576
11173169
11470055
12028741
12884887
14616189
15677600
16597572
16785218
16930857
16956865
17278675
17668330
18990547
19192861
19692689
20180662
20532873
20565154
20716302
 		CTD
444Cognition Disorders

View details

12062778
12628632
15893159
17565668
 		CTD
445Compression fractureOFFSIDES
446ConfabulationOFFSIDES
447Confusion2886842
11145498		CTD
448Congenital cystic kidney diseaseOFFSIDES
449Congenital pyelocaliectasisOFFSIDES
450Conjunctival depositOFFSIDES
451Cutis anserinaSIDER
452DebridementOFFSIDES
453DemyelinationOFFSIDES
454Denture wearerOFFSIDES
455Depressive disorder17055063
19110885		CTD
456DermatitisSIDER
457Developmental Disabilities6178811
19219093		CTD
458Device breakageOFFSIDES
459Device related infectionOFFSIDES
460DiabetesOFFSIDES
461Diabetes mellitus inadequate controlOFFSIDES
462Diabetic ulcerOFFSIDES
463Disorders of Excessive Somnolence11145498CTD
464Disturbance in sexual arousalSIDER
465DiverticulosisOFFSIDES
466DrowsinessOFFSIDES
SIDER
467Drug Overdose

View details

4936579
11744587
16910150
16997682
17852162
19263068
20028962
21439157
 		CTD
468Drug addictOFFSIDES
469Dry skinOFFSIDES
470Dyskinesia, Drug-Induced810889CTD
471DysmenorrheaOFFSIDES
472Ear congestionOFFSIDES
473Embryo Loss4586767CTD
474ErythemaOFFSIDES
SIDER
475ExcoriationOFFSIDES
476FibromyalgiaOFFSIDES
477Fistula repairOFFSIDES
478Flank PainOFFSIDES
479Flatulence4028630CTD
480Foaming at mouthCanada Vigilance: 1Canada Vigilance
481FractureSIDER
482Gait Disorders, Neurologic11783819CTD
483Galactorrhea-Hyperprolactinemia16675813CTD
484Gastric BypassOFFSIDES
485GlossitisSIDER
486GranulocytosisOFFSIDES
487Granuloma16931994CTD
488Grip strengthOFFSIDES
489HIV Infections14556883
15156430		CTD
490Hallucinations2886842
10199103
15454842		CTD
491Hearing Loss, Sudden19263068
20028962		CTD
492Heat StrokeCanada Vigilance: 1Canada Vigilance
493Hepatic Insufficiency16997682CTD
494Hepatic necrosisOFFSIDES
495Hepatopulmonary Syndrome20583080CTD
496Heroin Dependence

View details

56139
4028630
6108101
7869468
10768702
11173169
12859171
15477802
15608471
15717844
15964714
15986265
16085366
16162728
16238992
16389204
16496034
16759341
16814005
16865634
17026725
17222284
17278675
17378505
17628351
17784892
19150250
19339140
19540702
19930027
20180662
20532873
20827272
 		CTD
497HiccoughOFFSIDES
498Hormone level abnormalOFFSIDES
499Hospice CareOFFSIDES
500HydronephrosisOFFSIDES
501Hyperalgesia

View details

11027904
11376918
11427327
17325516
17906213
19818750
20163921
20178837
20184918
 		CTD
502Hyperglycemia2554359CTD
503Hyperglycemic Hyperosmolar Nonketotic Coma16997682CTD
504HyperpigmentationOFFSIDES
505Hyperprolactinemia21094671CTD
506HypogonadismSIDER
507HypotensiveSIDER
508Impaired quality of lifeCanada Vigilance: 1Canada Vigilance
509Implant site dischargeOFFSIDES
510Inappropriate schedule of drug administrationOFFSIDES
511Infusion site pruritusOFFSIDES
512Initial insomniaCanada Vigilance: 1Canada Vigilance
513Injection site dermatitisOFFSIDES
514Inspiratory capacity decreasedOFFSIDES
515Insulin-requiring type 2 diabetes mellitusOFFSIDES
516Intention tremorOFFSIDES
517Intentional self-injuryOFFSIDES
518Intervertebral Disc DegenerationOFFSIDES
519Ischemia4367894CTD
520Joint Range of Motion DecreasedOFFSIDES
521Lack of spontaneous speechOFFSIDES
522LacrimationSIDER
523Leukopenia neonatalOFFSIDES
524LightheadednessSIDER
525Lung Neoplasms7848904CTD
526MalabsorptionOFFSIDES
527Malignant neoplasm progressionOFFSIDES
528Mastication disorderOFFSIDES
529Medical device removalOFFSIDES
530Memory Disorders12062778CTD
531MenopauseCanada Vigilance: 1Canada Vigilance
532Middle insomniaCanada Vigilance: 1Canada Vigilance
533Monoclonal immunoglobulin presentOFFSIDES
534Motor Skills Disorders7121697
7121699		CTD
535Multiple MyelomaOFFSIDES
536Multiple Organ Failure16997682CTD
537Multiple drug overdoseOFFSIDES
538Muscle WeaknessOFFSIDES
539Muscle strainOFFSIDES
540Musculoskeletal chest painOFFSIDES
541Musculoskeletal discomfortOFFSIDES
542Myoglobinuria4936579CTD
543Narcotic intoxicationOFFSIDES
544Neonatal Abstinence Syndrome

View details

1883657
2567922
4748595
6178811
7820717
7873960
11042868
11454944
17291325
17701668
19219093
19690513
19931991
21142534
 		CTD
545Nephrogenic Fibrosing DermopathyOFFSIDES
546NephrolithiasisOFFSIDES
547Nerve BlockOFFSIDES
548NervousnessCanada Vigilance: 1Canada Vigilance
549Neuromuscular Manifestations6178811
7121699		CTD
550Neurotoxicity Syndromes19808992CTD
551Neutrophil count decreasedOFFSIDES
552No adverse eventCanada Vigilance: 1Canada Vigilance
553ObstructionOFFSIDES
554Occult blood positiveOFFSIDES
555Oliguria4936579CTD
556Opioid-Related Disorders

View details

2449617
2540995
8434657
9649976
9888118
9892294
10215673
10934576
11164690
12028741
12230351
12628632
12884887
15039761
15063917
15568612
15677600
15774410
15857742
15875343
15961013
15977920
16675813
17286641
17373567
17394991
17480178
17517480
17565668
17668330
18032235
18720267
18956527
19258204
19392907
19760630
19931991
20177760
21142534
 		CTD
557Oral Cavity FistulaOFFSIDES
558Oral fungal infectionOFFSIDES
559Oral polypectomyOFFSIDES
560OsteomyelitisOFFSIDES
561Otitis Media6178811CTD
562Pain, Postoperative4069717
11782325
15310347		CTD
563Panic Disorder1314016CTD
564PapillomaOFFSIDES
565Paranoid Personality DisorderOFFSIDES
566Paraparesis, Spastic14622789CTD
567Partner stressCanada Vigilance: 1Canada Vigilance
568Peptostreptococcus infectionOFFSIDES
569PericarditisOFFSIDES
570Peripheral Nervous System Diseases20184918CTD
571Perirectal abscessOFFSIDES
572PhlebitisSIDER
573PiloerectionSIDER
574Pilonidal CystOFFSIDES
575Poor quality drug administeredOFFSIDES
576Portal hypertensive gastropathyOFFSIDES
577Postoperative Complications4069717CTD
578Precancerous cells presentOFFSIDES
579Prenatal Exposure Delayed Effects

View details

2636852
2742277
7121697
7121699
7683453
11454944
17701668
19219093
19690513
20189732
21142534
 		CTD
580Primary sequestrumOFFSIDES
581Productive CoughOFFSIDES
582Prostate examination abnormalOFFSIDES
583Prosthesis ImplantationOFFSIDES
584Psychomotor Agitation2886842
19808992		CTD
585Psychomotor Disorders12062778
19219093		CTD
586Psychoses, Substance-Induced10199103CTD
587Psychotic Disorders17890983CTD
588Pulmonary Edema4936579
16997682
19782326		CTD
589Pulmonary function test decreasedSIDER
590Pupil Disorders9173676CTD
591Purulent dischargeOFFSIDES
592PyelonephritisOFFSIDES
593RednessSIDER
594Reflex Sympathetic Dystrophy11783819CTD
595Renal cystOFFSIDES
596Respiration Disorders14550686
18022786		CTD
597Respiratory Aspiration16997682CTD
598Respiratory Distress Syndrome, Adult1436354CTD
599Respiratory Insufficiency

View details

11145498
11744587
15278196
15454842
17968993
19819313
 		CTD
600Retinal Diseases4367894CTD
601Retroperitoneal lymphadenopathyOFFSIDES
602ScabOFFSIDES
603SeromaOFFSIDES
604Serum testosterone decreasedSIDER
605Shock, Cardiogenic16997682CTD
606Sjogren's SyndromeOFFSIDES
607Skin IndurationOFFSIDES
608Skin hypertrophyOFFSIDES
609Skin lacerationOFFSIDES
610Skin tightnessOFFSIDES
611Sleep Apnea, Central11255580
16162728		CTD
612Sleep Initiation and Maintenance Disorders19775835CTD
613Sleep TalkingCanada Vigilance: 1Canada Vigilance
614Sleep Wake Disorders16154297
20483171		CTD
615Spasm14622789CTD
616Speech Disorders6108101
19808992		CTD
617Spina Bifida OccultaOFFSIDES
618Spinal Cord Diseases4586767CTD
619Spinal Stenosis16089243CTD
620Spinal column stenosisOFFSIDES
621Stasis dermatitisOFFSIDES
622Stem cell transplantOFFSIDES
623Stupor4367894CTD
624Substance Withdrawal Syndrome

View details

45902
56139
1163365
2449617
2498296
2540995
4028630
4433085
6734421
6794076
7224382
7869468
8201637
8434657
9649976
10786356
10862807
10993435
11765307
12628632
12793936
15538140
15830825
16395081
19760630
 		CTD
625Substance-Related Disorders

View details

1436354
2742277
3177071
5036504
10862807
10934576
11058673
14665804
 		CTD
626SweatingSIDER
627Tachycardia, Ventricular15232338CTD
628Temperature intoleranceCanada Vigilance: 1Canada Vigilance
629Therapeutic product effect incompleteCanada Vigilance: 1Canada Vigilance
630Therapy cessationOFFSIDES
631ThoracotomyOFFSIDES
632Thrombosis in deviceOFFSIDES
633Tooth ExtractionOFFSIDES
634Tooth InfectionCanada Vigilance: 1Canada Vigilance
OFFSIDES
635Tooth Injuries17687962CTD
636Tooth LossCanada Vigilance: 217687962CTD
OFFSIDES
Canada Vigilance
637ToothacheCanada Vigilance: 1Canada Vigilance
638Torsades de Pointes

View details

12230351
14556883
14587370
15232338
15387312
15471174
15550974
15774410
15795907
15875343
15918160
15977920
15986265
16178046
16865634
16911733
17026725
17394991
17480178
17697226
18022786
18032235
18178408
18277734
18686025
19358226
19386945
19437394
19930027
 		CTD
639Troponin increasedOFFSIDES
640Ureteral stent insertionOFFSIDES
641Venous thrombosis limbOFFSIDES
642Visual disturbanceSIDER
643Walking aid userOFFSIDES
644Weight GainOFFSIDES
645Wound ComplicationOFFSIDES
646Wound dehiscenceOFFSIDES
647Wound infection fungalOFFSIDES
648YawningSIDER
649kyphosisOFFSIDES
650muscle injuryOFFSIDES
651prostatitisOFFSIDES
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