MetaADEDB 2.0 @ LMMD
Gemifloxacin
(JIYMVSQRGZEYAX-CWUUNJJBSA-N)
Structure
SMILES
CS(=O)(=O)O.NCC1CN(C/C/1=N\OC)c1nc2c(cc1F)c(=O)c(cn2C1CC1)C(=O)O
Molecular Formula:
C19H24FN5O7S
Molecular Weight:
485.487
Log P:
2.3161
Hydrogen Bond Acceptor:
12
Hydrogen Bond Donor:
3
TPSA:
185.79
CAS Number(s):
204519-65-3; 210353-53-0
Synonym(s)
1.
Gemifloxacin
2.
7-(3-aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)-naphthyridine-3-carboxylic acid
3.
Factive
4.
Gemifloxacin Mesylate
5.
LB 20304
6.
LB-20304
7.
LB20304
8.
SB 265805
9.
SB-265805
10.
SB265805
External Link(s)
MeSHD000077735
PubChem Compound9588170
ChEBI53749
CHEMBLCHEMBL1200621
KEGGdr:D02471
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1UrticariaFAERS: 47US FAERS
2Rash erythematousFAERS: 32US FAERS
3Drug ineffectiveFAERS: 28US FAERS
4PruritusFAERS: 18US FAERS
5NauseaFAERS: 17US FAERS
6DizzinessFAERS: 11US FAERS
7HeadacheFAERS: 9US FAERS
8HypersensitivityFAERS: 9
Canada Vigilance: 1		Canada Vigilance
US FAERS
9VomitingFAERS: 9US FAERS
10PainFAERS: 8US FAERS
11AstheniaFAERS: 7US FAERS
12SomnolenceFAERS: 7US FAERS
13Abdominal discomfortFAERS: 6US FAERS
14Clostridium colitisFAERS: 6US FAERS
15ErythemaFAERS: 5US FAERS
16PneumoniaFAERS: 5US FAERS
17Stevens-Johnson SyndromeFAERS: 5US FAERS
18Back PainFAERS: 4US FAERS
19DysgeusiaFAERS: 4US FAERS
20MyalgiaFAERS: 4US FAERS
21TachycardiaFAERS: 4US FAERS
22TremorFAERS: 4US FAERS
23Abdominal PainFAERS: 3US FAERS
24AgeusiaFAERS: 3US FAERS
25Alanine Aminotransferase IncreasedFAERS: 3US FAERS
26Anaphylactic shockFAERS: 3US FAERS
27AngioedemaFAERS: 3US FAERS
28Blood alkaline phosphatase increasedFAERS: 3US FAERS
29Burning sensationFAERS: 3US FAERS
30ChillsFAERS: 3US FAERS
31Drug toxicityFAERS: 3US FAERS
32Erythema MultiformeFAERS: 3US FAERS
33FatigueFAERS: 3US FAERS
34Feeling abnormalFAERS: 3US FAERS
35FlushingFAERS: 3US FAERS
36Joint swellingFAERS: 3US FAERS
37Oropharyngeal swellingFAERS: 3US FAERS
38SwellingFAERS: 3US FAERS
39AnosmiaFAERS: 2US FAERS
40Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
41Chest PainFAERS: 2US FAERS
42Clostridium difficile colitisFAERS: 2US FAERS
43DisorientationFAERS: 2US FAERS
44Gastrointestinal PainFAERS: 2US FAERS
45HyperparathyroidismFAERS: 2US FAERS
46LethargyFAERS: 2US FAERS
47MalaiseFAERS: 2US FAERS
48Muscle strainFAERS: 2US FAERS
49Ocular icterusFAERS: 2US FAERS
50Oral mucosal eruptionFAERS: 2US FAERS
51PhotophobiaFAERS: 2US FAERS
52PurpuraFAERS: 2US FAERS
53Rectal fissureFAERS: 2US FAERS
54Rotator cuff syndromeFAERS: 2US FAERS
55Serum SicknessFAERS: 2US FAERS
56SyncopeFAERS: 2US FAERS
57Therapy non-responderFAERS: 2US FAERS
58Visual disturbanceFAERS: 2US FAERS
59Vitamin D DeficiencyFAERS: 2US FAERS
60jaundiceFAERS: 2US FAERS
61AbasiaFAERS: 1US FAERS
62Abdominal tendernessFAERS: 1US FAERS
63AbscessFAERS: 1US FAERS
64AcarodermatitisFAERS: 1US FAERS
65Adverse eventFAERS: 1US FAERS
66AnxietyFAERS: 1US FAERS
67ArthralgiaFAERS: 1US FAERS
68ArthritisFAERS: 1US FAERS
69AsterixisFAERS: 1US FAERS
70AtelectasisFAERS: 1US FAERS
71BedriddenFAERS: 1US FAERS
72Blood creatine abnormalFAERS: 1US FAERS
73Blood creatinine increasedFAERS: 1US FAERS
74Blood urea abnormalFAERS: 1US FAERS
75Bone marrow granulomaFAERS: 1US FAERS
76Bone painFAERS: 1US FAERS
77CachexiaFAERS: 1US FAERS
78Capillary FragilityFAERS: 1US FAERS
79Cerebrovascular accidentFAERS: 1US FAERS
80Chest discomfortFAERS: 1US FAERS
81ChokingFAERS: 1US FAERS
82CholelithiasisFAERS: 1US FAERS
83ConstipationFAERS: 1US FAERS
84Depressed Level of ConsciousnessFAERS: 1US FAERS
85Dermatitis acneiformFAERS: 1US FAERS
86DermatitisFAERS: 1US FAERS
87Diabetes MellitusFAERS: 1US FAERS
88DyspepsiaFAERS: 1US FAERS
89DysuriaFAERS: 1US FAERS
90Economic problemFAERS: 1US FAERS
91EosinophiliaFAERS: 1US FAERS
92Eye painFAERS: 1US FAERS
93Facial PainFAERS: 1US FAERS
94Feeling ColdFAERS: 1US FAERS
95Feeling jitteryFAERS: 1US FAERS
96Foreign body aspirationFAERS: 1US FAERS
97Foreign body traumaFAERS: 1US FAERS
98GoutFAERS: 1US FAERS
99HypoxiaFAERS: 1US FAERS
100Impaired work abilityFAERS: 1US FAERS
101InfectionFAERS: 1US FAERS
102Infectious MononucleosisFAERS: 1US FAERS
103LacerationFAERS: 1US FAERS
104Lip swellingFAERS: 1US FAERS
105MeningitisFAERS: 1US FAERS
106Mental status changesFAERS: 1US FAERS
107Musculoskeletal chest painFAERS: 1US FAERS
108MyokymiaFAERS: 1US FAERS
109NervousnessFAERS: 1US FAERS
110Night sweatsFAERS: 1US FAERS
111Oral candidiasisFAERS: 1US FAERS
112PalpitationsFAERS: 1US FAERS
113Pityriasis RoseaFAERS: 1US FAERS
114ProctitisFAERS: 1US FAERS
115Prothrombin level decreasedFAERS: 1US FAERS
116Psychiatric symptomFAERS: 1US FAERS
117Pulmonary congestionFAERS: 1US FAERS
118RalesFAERS: 1US FAERS
119Renal painFAERS: 1US FAERS
120Respiratory arrestFAERS: 1US FAERS
121Respiratory distressFAERS: 1US FAERS
122RestlessnessFAERS: 1US FAERS
123RetchingFAERS: 1US FAERS
124Retinal DetachmentFAERS: 1US FAERS
125Rheumatoid ArthritisFAERS: 1US FAERS
126RosaceaFAERS: 1US FAERS
127ScabFAERS: 1US FAERS
128Sigmoidoscopy abnormalFAERS: 1US FAERS
129Similar reaction on previous exposure to drugFAERS: 1US FAERS
130SinusitisFAERS: 1US FAERS
131SunburnFAERS: 1US FAERS
132Therapeutic response unexpectedFAERS: 1US FAERS
133Throat irritationFAERS: 1US FAERS
134Urticaria localisedFAERS: 1US FAERS
135VertigoFAERS: 1US FAERS
136Visual ImpairmentFAERS: 1US FAERS
137Vitreous floatersFAERS: 1US FAERS
138muscle injuryFAERS: 1US FAERS
139Pharyngeal swellingCanada Vigilance: 1Canada Vigilance
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