MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Niacinamide

(DFPAKSUCGFBDDF-UHFFFAOYSA-N)

Structure

SMILES: NC(=O)c1cccnc1
Type(s): Approved; Investigational
ATC code(s): A11HA01
Molecular Formula:: C6H6N2O
Molecular Weight:: 122.125
Log P:: 0.8808
Hydrogen Bond Acceptor:: 3
Hydrogen Bond Donor:: 1
TPSA:: 55.98
CAS Number(s):: 98-92-0

Synonym(s)

Niacinamide

Nicotinamide

Vitamin B 3

Vitamin PP

3-Pyridinecarboxamide

Enduramide

Nicobion

Nicotinsäureamid Jenapharm

Papulex

10.

Vitamin B3

11.

3 Pyridinecarboxamide

12.

B 3, Vitamin

13.

B3, Vitamin

14.

Jenapharm, Nicotinsäureamid

External Link(s)

MeSH	D009536
PubChem Compound	936
BindingDB	27507
ChEBI	17154
CHEMBL	CHEMBL1140
DrugBank	DB02701
DrugCentral	1906
KEGG	cpd:C00153 dr:D00036
ZINC	5878

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Accidental exposure to product	FAERS: 1		US FAERS
2	Burning sensation	FAERS: 1		US FAERS
3	Nausea	FAERS: 1		US FAERS
4	Pain	FAERS: 1		US FAERS
5	Pruritus	FAERS: 1 Canada Vigilance: 2		Canada Vigilance US FAERS
6	Abdominal Pain			OFFSIDES
7	Abdominal discomfort			OFFSIDES
8	Acidosis			OFFSIDES
9	Acute bronchitis			OFFSIDES
10	Alanine Aminotransferase Increased			OFFSIDES
11	Aldolase increased			OFFSIDES
12	Anorexia			OFFSIDES
13	Antinuclear antibody increased			OFFSIDES
14	Apathy			OFFSIDES
15	Aphonia			OFFSIDES
16	Aspergillosis			OFFSIDES
17	Asthenia			OFFSIDES
18	Atherosclerosis			OFFSIDES
19	Blepharospasm			OFFSIDES
20	Blood creatine phosphokinase increased			OFFSIDES
21	Blood osmolarity decreased			OFFSIDES
22	Blood sodium			OFFSIDES
23	Brain Infarction		19288225	CTD
24	Brain Ischemia		19288225	CTD
25	Brain scan abnormal			OFFSIDES
26	Chemical and Drug Induced Liver Injury		7590113 8742498 21630391	CTD
27	Child Behavior Disorders		150790	CTD
28	Chromaturia			OFFSIDES
29	Cleft Palate		4269736	CTD
30	Confabulation			OFFSIDES
31	Demyelination			OFFSIDES
32	Dermatofibrosarcoma			OFFSIDES
33	Dermatomyositis			OFFSIDES
34	Diabetes Mellitus, Experimental		View details 2975197 18675532 19059388 20307516 20696151 20869956 21382363 21439372 21630391 22056647 23406761 25849131 25999625 29247773 29421519 29944876	CTD
35	Diabetic Cardiomyopathies		23677724	CTD
36	Diarrhea			OFFSIDES
37	Dyspepsia			OFFSIDES
38	Dysuria			OFFSIDES
39	Erectile dysfunction			OFFSIDES
40	Fatty Liver			OFFSIDES
41	Fibromyalgia			OFFSIDES
42	Flat affect			OFFSIDES
43	Flushing	Canada Vigilance: 2		Canada Vigilance
44	Gastrointestinal perforation			OFFSIDES
45	Hepatitis C			OFFSIDES
46	Hypercholesterolemia		20696151	CTD
47	Hyperglycemia		View details 19059388 21382363 21630391 23406761 23466488 25849131 25999625 29247773 29421519	CTD
48	Hyperlipoproteinemias		20696151	CTD
49	Hypertriglyceridemia		20696151	CTD
50	Hypoalphalipoproteinemias		20696151	CTD
51	Infection			OFFSIDES
52	Kidney Diseases		21630391	CTD
53	Kidney Failure			OFFSIDES
54	Limb Deformities, Congenital		4269736	CTD
55	Lung Injury			OFFSIDES
56	Musculoskeletal stiffness			OFFSIDES
57	Nerve Degeneration		8298082	CTD
58	Nodule			OFFSIDES
59	Occult blood positive			OFFSIDES
60	Ocular icterus			OFFSIDES
61	Patellofemoral Pain Syndrome			OFFSIDES
62	Pelvic venous thrombosis			OFFSIDES
63	Protein total decreased			OFFSIDES
64	Pulmonary vascular disorder			OFFSIDES
65	Rectal polyp			OFFSIDES
66	Rheumatoid Nodule			OFFSIDES
67	Rosacea		18189062	CTD
68	Seizures		2931304	CTD
69	Skin Neoplasms		24792773	CTD
70	Skin irritation	Canada Vigilance: 1		Canada Vigilance
71	Spinal column stenosis			OFFSIDES
72	Synovitis			OFFSIDES
73	Tendinitis			OFFSIDES
74	Thrombophlebitis			OFFSIDES
75	Tinea Versicolor			OFFSIDES
76	Vascular insufficiency			OFFSIDES
77	Vasculitis		9131432	CTD
78	Ventricular Dysfunction, Left		23677724	CTD
79	Walking aid user			OFFSIDES

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237