MetaADEDB 2.0 @ LMMD
gadoversetamide
(HBEAOBRDTOXWRZ-UHFFFAOYSA-K)
Structure
SMILES
COCCNC(=O)CN(CC(=O)[O-])CCN(CC(=O)[O-])CCN(CC(=O)NCCOC)CC(=O)[O-].[Gd+3]
Type(s)
Approved; Investigational
ATC code(s)
V08CA06
Molecular Formula:
C20H34GdN5O10
Molecular Weight:
661.761
Log P:
-6.5509
Hydrogen Bond Acceptor:
15
Hydrogen Bond Donor:
2
TPSA:
206.77
CAS Number(s):
131069-91-5
Synonym(s)
1.
gadoversetamide
2.
OptiMARK
External Link(s)
MeSHC112666
PubChem Compound6435809
444013
ChEBI31644
CHEMBLCHEMBL1200457
DrugBankDB00538
KEGGdr:D01646
Therapeutic Target DatabaseD0X0GI
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Nephrogenic Systemic FibrosisFAERS: 53SIDER
US FAERS
2NauseaFAERS: 16SIDER
US FAERS
3PainFAERS: 16OFFSIDES
SIDER
US FAERS
4HeadacheFAERS: 12SIDER
US FAERS
5UrticariaFAERS: 12SIDER
US FAERS
6DizzinessFAERS: 11SIDER
US FAERS
7Medication residue presentFAERS: 10US FAERS
8Drug administration errorFAERS: 8OFFSIDES
US FAERS
9ErythemaFAERS: 8OFFSIDES
SIDER
US FAERS
10PruritusFAERS: 8SIDER
US FAERS
11Throat irritationFAERS: 7SIDER
US FAERS
12VomitingFAERS: 7SIDER
US FAERS
13ChillsFAERS: 6SIDER
US FAERS
14DysgeusiaFAERS: 6SIDER
US FAERS
15Feeling abnormalFAERS: 6SIDER
US FAERS
16Gadolinium deposition diseaseFAERS: 6US FAERS
17Injection site extravasationFAERS: 6US FAERS
18SyncopeFAERS: 6SIDER
US FAERS
19AnxietyFAERS: 5OFFSIDES
SIDER
US FAERS
20ArthralgiaFAERS: 5SIDER
US FAERS
21AstheniaFAERS: 5OFFSIDES
SIDER
US FAERS
22Burning sensationFAERS: 5OFFSIDES
SIDER
US FAERS
23DysphoniaFAERS: 4SIDER
US FAERS
24Emotional distressFAERS: 4OFFSIDES
US FAERS
25Mental impairmentFAERS: 4US FAERS
26MyalgiaFAERS: 4SIDER
US FAERS
27Nephrogenic Fibrosing DermopathyFAERS: 418425843CTD
OFFSIDES
US FAERS
28PalpitationsFAERS: 4SIDER
US FAERS
29WheezingFAERS: 4US FAERS
30Chest PainFAERS: 3SIDER
US FAERS
31DisorientationFAERS: 3SIDER
US FAERS
32Drug prescribing errorFAERS: 3OFFSIDES
US FAERS
33Dry skinFAERS: 3OFFSIDES
SIDER
US FAERS
34FatigueFAERS: 3OFFSIDES
SIDER
US FAERS
35Injection site injuryFAERS: 3OFFSIDES
US FAERS
36MalaiseFAERS: 3SIDER
US FAERS
37Post procedural complicationFAERS: 3US FAERS
38Quality of life decreasedFAERS: 3OFFSIDES
US FAERS
39Renal painFAERS: 3US FAERS
40TremorFAERS: 3SIDER
US FAERS
41Tubo-ovarian abscessFAERS: 3US FAERS
42VertigoFAERS: 3SIDER
US FAERS
43AlopeciaFAERS: 2US FAERS
44Auricular swellingFAERS: 2US FAERS
45Bone painFAERS: 2OFFSIDES
US FAERS
46BursitisFAERS: 2US FAERS
47Cardiac ArrestFAERS: 2US FAERS
48Chest discomfortFAERS: 2SIDER
US FAERS
49Cold sweatFAERS: 2SIDER
US FAERS
50Contrast media reactionFAERS: 2US FAERS
51DermatitisFAERS: 2SIDER
US FAERS
52Device dislocationFAERS: 2US FAERS
53Drug ineffectiveFAERS: 2US FAERS
54Eye irritationFAERS: 2US FAERS
55Eye painFAERS: 2SIDER
US FAERS
56Feeling ColdFAERS: 2US FAERS
57FibrosisFAERS: 2US FAERS
58FormicationFAERS: 2OFFSIDES
US FAERS
59Head discomfortFAERS: 2US FAERS
60HypersensitivityFAERS: 2SIDER
US FAERS
61Infusion Site ExtravasationFAERS: 2US FAERS
62Injection site erythemaFAERS: 2US FAERS
63Joint stiffnessFAERS: 2OFFSIDES
US FAERS
64NeurodermatitisFAERS: 2OFFSIDES
US FAERS
65Pericardial effusionFAERS: 2OFFSIDES
US FAERS
66Respiratory FailureFAERS: 2OFFSIDES
US FAERS
67Respiratory distressFAERS: 2US FAERS
68Skin lesionFAERS: 2OFFSIDES
US FAERS
69SneezingFAERS: 2SIDER
US FAERS
70TachycardiaFAERS: 2SIDER
US FAERS
71TinnitusFAERS: 2SIDER
US FAERS
72Toxicity to various agentsFAERS: 2US FAERS
73Vitreous floatersFAERS: 2US FAERS
74Abdominal PainFAERS: 1SIDER
US FAERS
75Abdominal discomfortFAERS: 1US FAERS
76Angina PectorisFAERS: 1US FAERS
77ArthritisFAERS: 1OFFSIDES
US FAERS
78AsthmaFAERS: 1SIDER
US FAERS
79Blood potassium decreasedFAERS: 1US FAERS
80Contrast media allergyFAERS: 1US FAERS
81Coronary Artery DiseaseFAERS: 1US FAERS
82Depressed moodFAERS: 1US FAERS
83DiplopiaFAERS: 1SIDER
US FAERS
84Drug clearance decreasedFAERS: 1US FAERS
85Drug level increasedFAERS: 1US FAERS
86Ejection Fraction DecreasedFAERS: 1OFFSIDES
US FAERS
87Electrocardiogram ST segment abnormalFAERS: 1US FAERS
88ExcoriationFAERS: 1OFFSIDES
US FAERS
89Expired product administeredFAERS: 1US FAERS
90FlushingFAERS: 1SIDER
US FAERS
91Impaired work abilityFAERS: 1OFFSIDES
US FAERS
92Incorrect drug administration rateFAERS: 1US FAERS
93Injection site coldnessFAERS: 1US FAERS
94Injection site painFAERS: 1US FAERS
95Injection site warmthFAERS: 1US FAERS
96Joint sprainFAERS: 1US FAERS
97Joint swellingFAERS: 1US FAERS
98LethargyFAERS: 1US FAERS
99Limb discomfortFAERS: 1US FAERS
100Lip swellingFAERS: 1US FAERS
101Musculoskeletal chest painFAERS: 1OFFSIDES
US FAERS
102Musculoskeletal stiffnessFAERS: 1OFFSIDES
SIDER
US FAERS
103Myocardial InfarctionFAERS: 1US FAERS
104Oral pruritusFAERS: 1US FAERS
105Oropharyngeal discomfortFAERS: 1US FAERS
106Oropharyngeal painFAERS: 1US FAERS
107OsteomyelitisFAERS: 1OFFSIDES
US FAERS
108PapuleFAERS: 1US FAERS
109ParaparesisFAERS: 1US FAERS
110Peritoneal DialysisFAERS: 1US FAERS
111PresyncopeFAERS: 1US FAERS
112Product residue presentFAERS: 1US FAERS
113Skin hypertrophyFAERS: 1OFFSIDES
US FAERS
114Skin tightnessFAERS: 1OFFSIDES
US FAERS
115SomnolenceFAERS: 1SIDER
US FAERS
116StridorFAERS: 1US FAERS
117Unresponsive to stimuliFAERS: 1US FAERS
118Vascular graft complicationFAERS: 1OFFSIDES
US FAERS
119Venous stenosisFAERS: 1OFFSIDES
US FAERS
120Vibratory sense increasedFAERS: 1US FAERS
121AbasiaOFFSIDES
122Abdominal AbscessOFFSIDES
123Abdominal wound dehiscenceOFFSIDES
124Abnormal cervical smearOFFSIDES
125AbscessOFFSIDES
126AbuseOFFSIDES
127AcanthosisOFFSIDES
128Accidental needle stickOFFSIDES
129AcneOFFSIDES
130Activities of daily living impairedOFFSIDES
131Acute respiratory failureOFFSIDES
132Acute sinusitisOFFSIDES
133AdenocarcinomaOFFSIDES
134Administration site reactionSIDER
135AgitationSIDER
136Alanine Aminotransferase IncreasedSIDER
137AmblyopiaSIDER
138Ammonia increasedOFFSIDES
139AmnesiaSIDER
140AmputationOFFSIDES
141Anal FissureOFFSIDES
142Anaphylactic shockSIDER
143AnhedoniaOFFSIDES
144AnhidrosisOFFSIDES
145Anorectal discomfortSIDER
146AnorexiaOFFSIDES
SIDER
147Aortic embolusOFFSIDES
148Application site reactionSIDER
149ArteriosclerosisOFFSIDES
150Arteriovenous fistula occlusionOFFSIDES
151Arteriovenous fistula site complicationOFFSIDES
152Arteriovenous graft site abscessOFFSIDES
153Arteriovenous graft thrombosisOFFSIDES
154ArthrofibrosisOFFSIDES
155AscitesOFFSIDES
156Aspiration PneumoniaOFFSIDES
157Asthenic conditionsSIDER
158AtelectasisOFFSIDES
159Atrial thrombosisOFFSIDES
160Avascular necrosisOFFSIDES
161Axillary vein thrombosisOFFSIDES
162Back PainSIDER
163Bacterial EndocarditisOFFSIDES
164Basal cell carcinomaOFFSIDES
165BedriddenOFFSIDES
166Biliary dilatationOFFSIDES
167BlepharochalasisOFFSIDES
168Blood calcium abnormalSIDER
169Blood creatine phosphokinase increasedSIDER
170Blood creatinine increasedSIDER
171Blood glucose decreasedOFFSIDES
172Bone density increasedOFFSIDES
173Bone lesionOFFSIDES
174BronchiectasisSIDER
175BronchitisOFFSIDES
176BronchopneumoniaOFFSIDES
177BronchospasmSIDER
178CalcinosisOFFSIDES
179CalciphylaxisOFFSIDES
180CataractOFFSIDES
181Catheter related infectionOFFSIDES
182Catheter site erythemaOFFSIDES
183CellulitisOFFSIDES
184Cerebral atrophyOFFSIDES
185Cervicobrachial syndromeOFFSIDES
186CholangiolitisOFFSIDES
187CholecystitisOFFSIDES
188Chronic Obstructive Airway DiseaseOFFSIDES
189Clostridium difficile colitisOFFSIDES
190ClubbingOFFSIDES
191ClumsinessOFFSIDES
192Coagulation test abnormalOFFSIDES
193ColitisOFFSIDES
194Colon adenomaOFFSIDES
195Congenital tricuspid valve incompetenceOFFSIDES
196Conjunctival depositOFFSIDES
197ConjunctivitisSIDER
198ConstipationSIDER
199ContractureOFFSIDES
200Cramps of lower extremitiesSIDER
201Creatine Phosphokinase IncreasedSIDER
202Creatinine increasedSIDER
203DemyelinationOFFSIDES
204Device related infectionOFFSIDES
205Diabetic ulcerOFFSIDES
206Diastolic dysfunctionOFFSIDES
207DiscomfortSIDER
208DiverticulosisOFFSIDES
209DiverticulumOFFSIDES
210DuodenitisOFFSIDES
211DyspepsiaSIDER
212DysuriaSIDER
213Ear and labyrinth disordersSIDER
214EcchymosisSIDER
215EncephalomalaciaOFFSIDES
216End stage AIDSSIDER
217EndophthalmitisSIDER
218EntropionOFFSIDES
219EpistaxisSIDER
220EructationSIDER
221Erythema MultiformeSIDER
222EscharOFFSIDES
223Eustachian tube disorderOFFSIDES
224Exfoliative rashOFFSIDES
225ExophthalmosOFFSIDES
226Extremity contractureOFFSIDES
227Eye inflammationOFFSIDES
228Femoral artery occlusionOFFSIDES
229FlatulenceSIDER
230Fluid overloadOFFSIDES
231GangreneOFFSIDES
232Gastric ulcerSIDER
233GastroenteritisOFFSIDES
234Gastrointestinal PainSIDER
235Gastrointestinal perforationSIDER
236General physical health deteriorationOFFSIDES
237GoutOFFSIDES
238GranulocytosisOFFSIDES
239HemiparesisOFFSIDES
240HyperacusisSIDER
241HyperkeratosisOFFSIDES
242HyperparathyroidismOFFSIDES
243HyperpigmentationOFFSIDES
244HyperreflexiaSIDER
245Hypertrophic CardiomyopathyOFFSIDES
246HypogonadismOFFSIDES
247HypoparathyroidismOFFSIDES
248HyporeflexiaSIDER
249HypotensionSIDER
250IleitisOFFSIDES
251Impaired gastric emptyingOFFSIDES
252Impaired self-careOFFSIDES
253IndurationOFFSIDES
254InfectionOFFSIDES
255InfluenzaSIDER
256Infusion site mobility decreasedOFFSIDES
257Injection Site ReactionSIDER
258Injection site inflammationSIDER
259Intervertebral Disc DegenerationOFFSIDES
260Intervertebral disc disorderOFFSIDES
261Joint Range of Motion DecreasedOFFSIDES
262KeratopathyOFFSIDES
263Klebsiella sepsisOFFSIDES
264LaryngospasmSIDER
265Left Ventricular HypertrophyOFFSIDES
266Left atrial dilatationOFFSIDES
267LichenificationOFFSIDES
268Life expectancy shortenedOFFSIDES
269Limb injuryOFFSIDES
270Livedo ReticularisOFFSIDES
271Local reactionSIDER
272Lung infection pseudomonalOFFSIDES
273LymphedemaOFFSIDES
274Malignant HypertensionOFFSIDES
275Mallory-Weiss SyndromeOFFSIDES
276MalnutritionSIDER
277MeningitisSIDER
278Mental status changesOFFSIDES
279Metabolic acidosisOFFSIDES
280MetaplasiaOFFSIDES
281MetrorrhagiaSIDER
282Mitral Valve StenosisOFFSIDES
283MorpheaOFFSIDES
284Muscle FatigueOFFSIDES
285Muscle WeaknessOFFSIDES
286Muscle fibrosisOFFSIDES
287Muscle tightnessOFFSIDES
288Musculoskeletal discomfortOFFSIDES
SIDER
289Myocardial fibrosisOFFSIDES
290MyosclerosisOFFSIDES
291NasopharyngitisSIDER
292Neck PainSIDER
293Neck stiffnessSIDER
294NervousnessSIDER
295NeuralgiaOFFSIDES
296Nodule on extremityOFFSIDES
297Nuchal RigiditySIDER
298NumbnessSIDER
299Occult blood positiveOFFSIDES
300Ocular icterusOFFSIDES
301OliguriaSIDER
302Open woundOFFSIDES
303OsteopeniaOFFSIDES
304OsteoporosisOFFSIDES
305Pain of skinOFFSIDES
306PallorSIDER
307Pelvic PainSIDER
308PericarditisOFFSIDES
309Peripheral arterial occlusive diseaseOFFSIDES
310Peritoneal InfectionOFFSIDES
311PeritonitisOFFSIDES
312PharyngitisSIDER
313Physical disabilityOFFSIDES
314PingueculaOFFSIDES
315PleurisyOFFSIDES
316PneumoniaSIDER
317PneumothoraxOFFSIDES
318Polymyalgia RheumaticaOFFSIDES
319PolyneuropathyOFFSIDES
320Portal HypertensionOFFSIDES
321Post inflammatory pigmentation changeOFFSIDES
322Post procedural discomfortOFFSIDES
323Postoperative renal failureOFFSIDES
324Prostate cancer recurrentOFFSIDES
325Pulmonary EosinophiliaOFFSIDES
326Pulmonary HypertensionOFFSIDES
327Pulmonary function test decreasedOFFSIDES
328Pulmonary vascular disorderOFFSIDES
329PyonephrosisOFFSIDES
330PyuriaOFFSIDES
331QRS axis abnormalOFFSIDES
332QuadriparesisOFFSIDES
333Rectal tenesmusSIDER
334Renal Artery StenosisOFFSIDES
335Renal cystOFFSIDES
336Retinal vascular thrombosisOFFSIDES
337RhinitisSIDER
338ScabOFFSIDES
339ScleritisOFFSIDES
340SclerodactyliaOFFSIDES
341SclerodermaOFFSIDES
342Sebaceous hyperplasiaOFFSIDES
343ShockSIDER
344Shunt infectionOFFSIDES
345Sinus bradycardiaOFFSIDES
346SinusitisOFFSIDES
SIDER
347Skin ErosionOFFSIDES
348Skin IndurationOFFSIDES
349Skin WrinklingOFFSIDES
350Skin necrosisOFFSIDES
351Splenic InfarctionOFFSIDES
352SpondylitisOFFSIDES
353Staphylococcal osteomyelitisOFFSIDES
354Stasis dermatitisOFFSIDES
355StressOFFSIDES
356Subcutaneous noduleOFFSIDES
357Superior Vena Cava SyndromeOFFSIDES
358TensionSIDER
359ThirstSIDER
360ThrombocytopeniaSIDER
361ThrombophlebitisSIDER
362Thrombosis in deviceOFFSIDES
363Tracheal StenosisOFFSIDES
364Trigeminal palsyOFFSIDES
365Urinary tract infectionSIDER
366Urine electrolytes abnormalSIDER
367Uterine abscessOFFSIDES
368UvulitisOFFSIDES
369Vascular calcificationOFFSIDES
370Vascular stenosisOFFSIDES
371Vasodilation procedureSIDER
372VasodilationSIDER
373VasospasmSIDER
374Venous InsufficiencyOFFSIDES
375Ventricular hypokinesiaOFFSIDES
376Wheelchair userOFFSIDES
377Wound infection staphylococcalOFFSIDES
378XerosisOFFSIDES
379effusionOFFSIDES
380fibromaOFFSIDES
381keratoacanthomaOFFSIDES
382nervous system disorderSIDER
383prostatitisOFFSIDES
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