MetaADEDB 2.0 @ LMMD
Benztropine
(GIJXKZJWITVLHI-YOFSQIOKSA-N)
Structure
SMILES
CN1[C@@H]2CC[C@H]1CC(C2)OC(c1ccccc1)c1ccccc1
Type(s)
Approved
ATC code(s)
N04AC01
Molecular Formula:
C21H25NO
Molecular Weight:
307.429
Log P:
4.3557
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
12.47
CAS Number(s):
86-13-5
Synonym(s)
1.
Benztropine
2.
Apo-Benztropine
3.
Bensylate
4.
Benzatropine
5.
Benzatropine Mesylate
6.
Benzatropine Methanesulfonate
7.
Benzatropine Methanesulfonate, Hydrobromide
8.
Benzatropine Methanesulfonate, Hydrobromide, (endo)-Isomer
9.
Benzatropine Methanesulfonate, Hydrochloride, (endo)-Isomer
10.
Benztropine Mesylate
11.
Cogentin
12.
Cogentinol
13.
N-Methylbenztropine
14.
PMS-Benztropine
15.
Apo Benztropine
16.
Hydrobromide Benzatropine Methanesulfonate
17.
Mesylate, Benzatropine
18.
Mesylate, Benztropine
19.
Methanesulfonate, Benzatropine
20.
Methanesulfonate, Hydrobromide Benzatropine
21.
N Methylbenztropine
22.
PMS Benztropine
External Link(s)
MeSHD001590
PubChem Compound1201549
BindingDB50366775
ChEBI3048
94707
CHEMBLCHEMBL438151
CHEMBL1618180
CHEMBL1201203
DrugBankDB00245
DrugCentral333
IUPHAR/BPS Guide to PHARMACOLOGY7601
KEGGcpd:C06846
dr:D07511
ZINC968360
100068353
100036536
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DeliriumFAERS: 3

View details

CTD
US FAERS
2Memory impairmentFAERS: 3SIDER
US FAERS
3Eye painFAERS: 2US FAERS
4Mental status changesFAERS: 2OFFSIDES
US FAERS
5Urinary RetentionFAERS: 22258459CTD
SIDER
US FAERS
6AsthenopiaFAERS: 1US FAERS
7ConstipationFAERS: 1SIDER
US FAERS
8CycloplegiaFAERS: 1US FAERS
9DisorientationFAERS: 1SIDER
US FAERS
10DroolingFAERS: 1US FAERS
11DystoniaFAERS: 1

View details

CTD
OFFSIDES
US FAERS
12HeadacheFAERS: 1US FAERS
13HypotensionFAERS: 1US FAERS
14IleusFAERS: 1SIDER
US FAERS
15Intestinal ObstructionFAERS: 1OFFSIDES
US FAERS
16ParanoiaFAERS: 1OFFSIDES
US FAERS
17PneumoniaFAERS: 1US FAERS
18Poor quality sleepFAERS: 1US FAERS
19ProctitisFAERS: 1US FAERS
20PruritusFAERS: 1US FAERS
21Respiratory distressFAERS: 1US FAERS
22Toxicity to various agentsFAERS: 1US FAERS
23Troponin increasedFAERS: 1OFFSIDES
US FAERS
24Urinary tract infectionFAERS: 1US FAERS
25Visual ImpairmentFAERS: 1US FAERS
26treatment failureFAERS: 1US FAERS
27AbasiaOFFSIDES
28Abnormal visionOFFSIDES
29AbuliaOFFSIDES
30AbuseOFFSIDES
31Accidental overdoseOFFSIDES
32Acid refluxOFFSIDES
33AcidosisOFFSIDES
34Acquired pyloric stenosisOFFSIDES
35ActinomycosisOFFSIDES
36Activities of daily living impairedOFFSIDES
37Acute bronchitisOFFSIDES
38Acute sinusitisOFFSIDES
39Adverse eventOFFSIDES
40AgeusiaOFFSIDES
41Agonal death struggleOFFSIDES
42Akathisia, Drug-Induced6847973
10895402
CTD
43Alcohol abuseOFFSIDES
44Alcohol withdrawal syndromeOFFSIDES
45Alcoholic IntoxicationOFFSIDES
46AlopeciaOFFSIDES
47AlveolitisOFFSIDES
48AmenorrheaOFFSIDES
49Ammonia increasedOFFSIDES
50AmnesiaOFFSIDES
51AmphetaminesOFFSIDES
52Anal FissureOFFSIDES
53AngerOFFSIDES
54AnhedoniaOFFSIDES
55AnisocytosisOFFSIDES
56AnosmiaOFFSIDES
57Anti-platelet antibody positiveOFFSIDES
58Anticholinergic SyndromeOFFSIDES
59Anticoagulation drug level above therapeuticOFFSIDES
60Antiphospholipid AntibodiesOFFSIDES
61Antipsychotic drug level increasedOFFSIDES
62Antiviral drug level above therapeuticOFFSIDES
63Anxiety Disorders33969
4405503
CTD
64AnxietyOFFSIDES
65ApathySIDER
66ArteriosclerosisOFFSIDES
67ArthritisOFFSIDES
68ArthropathyOFFSIDES
69Artificial crown procedureOFFSIDES
70Aspartate aminotransferase decreasedOFFSIDES
71AspergillosisOFFSIDES
72Aspiration PneumoniaOFFSIDES
73AsthmaOFFSIDES
74AtelectasisOFFSIDES
75AthetosisOFFSIDES
76Atrial tachycardiaOFFSIDES
77Atrioventricular Septal DefectOFFSIDES
78AuraOFFSIDES
79Autonomic neuropathyOFFSIDES
80Basal Ganglia Diseases

View details

CTD
81Bed restOFFSIDES
82BelligerenceOFFSIDES
83Bipolar Disorder3381938
6512011
7962691
CTD
OFFSIDES
84Bipolar I disorderOFFSIDES
85BlepharitisOFFSIDES
86BlepharospasmOFFSIDES
87Blood GlucoseOFFSIDES
88Blood amylase increasedOFFSIDES
89Blood chloride decreasedOFFSIDES
90Blood cholesterol abnormalOFFSIDES
91Blood cholesterolOFFSIDES
92Blood count abnormalOFFSIDES
93Blood creatine phosphokinase MB increasedOFFSIDES
94Blood creatine phosphokinase increasedOFFSIDES
95Blood creatinine decreasedOFFSIDES
96Blood creatinine increasedOFFSIDES
97Blood glucose decreasedOFFSIDES
98Blood glucose fluctuationOFFSIDES
99Blood hyposmosisOFFSIDES
100Blood ketone body presentOFFSIDES
101Blood pH decreasedOFFSIDES
102Blood prolactin increasedOFFSIDES
103Blood sodium increasedOFFSIDES
104Blood sodiumOFFSIDES
105Blood triglycerides increasedOFFSIDES
106Blunted affectOFFSIDES
107Blurred visionOFFSIDES
108Bone density decreasedOFFSIDES
109Bone painOFFSIDES
110Borderline Personality DisorderOFFSIDES
111Bradycardia1575268CTD
OFFSIDES
112Breast hyperplasiaOFFSIDES
113Breast tendernessOFFSIDES
114BronchitisOFFSIDES
115BruxismOFFSIDES
116BursitisOFFSIDES
117CarcinomaOFFSIDES
118Cardioactive drug levelOFFSIDES
119Carotid artery occlusionOFFSIDES
120Catalepsy10058
20713114
CTD
121CataractOFFSIDES
122Catatonia1429421
4008454
4397415
CTD
OFFSIDES
123CellulitisOFFSIDES
124Cerebral atrophyOFFSIDES
125Cerebrovascular accidentSIDER
126Chemical and Drug Induced Liver Injury6886037CTD
127Chemotherapeutic drug level increasedOFFSIDES
128Chest PainOFFSIDES
129Chest wall painOFFSIDES
130Choking sensationOFFSIDES
131ChokingOFFSIDES
132CholecystitisOFFSIDES
133Chorea6879286
15321589
CTD
134Chronic Obstructive Airway DiseaseOFFSIDES
135Chronic sinusitisOFFSIDES
136Circumstance or information capable of leading to medication errorOFFSIDES
137ClonusOFFSIDES
138Cogwheel RigidityOFFSIDES
139Colonic Pseudo-ObstructionOFFSIDES
140Completed SuicideOFFSIDES
141ConfabulationOFFSIDES
142Confusion4405503CTD
143Congenital tricuspid valve incompetenceOFFSIDES
144Conjunctival abrasionOFFSIDES
145Consciousness fluctuatingOFFSIDES
146Corneal UlcerOFFSIDES
147Cutaneous CandidiasisOFFSIDES
148CystOFFSIDES
149DebridementOFFSIDES
150Decreased LibidoOFFSIDES
151Deglutition Disorders2224229
11569473
18305296
CTD
152DehydrationOFFSIDES
153Delusion of replacementOFFSIDES
154Dementia of the Alzheimer's type, with deliriumOFFSIDES
155DemyelinationOFFSIDES
156Dental abscessOFFSIDES
157Dental cariesOFFSIDES
158Depressed Level of ConsciousnessOFFSIDES
159Depressive disorder33969CTD
160DermatitisSIDER
161DermatophytosisOFFSIDES
162Developmental Coordination DisorderOFFSIDES
163DiabetesOFFSIDES
164Diabetes InsipidusOFFSIDES
165Diabetes mellitus inadequate controlOFFSIDES
166Diabetes with hyperosmolarityOFFSIDES
167Diabetic Autonomic NeuropathyOFFSIDES
168Diabetic FootOFFSIDES
169Diabetic NephropathyOFFSIDES
170Diabetic RetinopathyOFFSIDES
171Diabetic foot infectionOFFSIDES
172Diabetic gastropathyOFFSIDES
173Diabetic ulcerOFFSIDES
174DiarrheaOFFSIDES
175DiplopiaOFFSIDES
176Disease ProgressionOFFSIDES
177DiverticulumOFFSIDES
178DrowningOFFSIDES
179DrowsinessOFFSIDES
180Drug abuserOFFSIDES
181Drug addictOFFSIDES
182Drug ineffectiveCanada Vigilance: 1Canada Vigilance
183Drug screen positiveOFFSIDES
184Drug toxicityOFFSIDES
185Drug withdrawal headacheOFFSIDES
186DuodenitisOFFSIDES
187Dyskinesia, Drug-Induced1125690CTD
188DysmenorrheaOFFSIDES
189DysmorphismOFFSIDES
190Dysphonia18305296CTD
191Dysthymic DisorderOFFSIDES
192DysuriaOFFSIDES
SIDER
193EcholaliaOFFSIDES
194Economic problemOFFSIDES
195Electrocardiogram ST-T segment abnormalOFFSIDES
196Emotional disorderOFFSIDES
197Emotional distressOFFSIDES
198EncephalitisOFFSIDES
199Endodontic procedureOFFSIDES
200Enuresis20119596CTD
OFFSIDES
201Eosinophilic myocarditisOFFSIDES
202Epidural lipomatosisOFFSIDES
203Erectile dysfunction6837805CTD
204Erosive gastritisOFFSIDES
205Escherichia urinary tract infectionOFFSIDES
206Esophageal motility disorders8354511CTD
207Esotropia18090571CTD
208Essential HypertensionOFFSIDES
209Euphoric moodOFFSIDES
210ExcoriationOFFSIDES
211ExophthalmosOFFSIDES
212Failure to ThriveOFFSIDES
213Fatigue10917413CTD
OFFSIDES
214Fatty LiverOFFSIDES
215Feeling ColdOFFSIDES
216Feeling abnormalOFFSIDES
SIDER
217Fever5676585CTD
218FibromyalgiaOFFSIDES
219Flat affectOFFSIDES
SIDER
220Foreign body aspirationOFFSIDES
221FrustrationOFFSIDES
222GalactorrheaOFFSIDES
223GangreneOFFSIDES
224Gastric hypomotilityOFFSIDES
225GastroduodenitisOFFSIDES
226GastroenteritisOFFSIDES
227Gaze palsyOFFSIDES
228General physical health deteriorationOFFSIDES
229Genitourinary tract infectionOFFSIDES
230Gestational DiabetesOFFSIDES
231GranulocytosisOFFSIDES
232GranulomaOFFSIDES
233Hallucinations4405503CTD
234Head BangingOFFSIDES
235Hearing disabilityOFFSIDES
236Heat Stroke18025545CTD
OFFSIDES
SIDER
237HemiparesisOFFSIDES
238Hepatitis COFFSIDES
239HepatosplenomegalyOFFSIDES
240HerniaOFFSIDES
241Hormone level abnormalOFFSIDES
242HostilityOFFSIDES
243Hyperosmolar stateOFFSIDES
244HyperreflexiaOFFSIDES
245HypersensitivitySIDER
246Hypertensive heart diseaseOFFSIDES
247HypogonadismOFFSIDES
248HypoxiaOFFSIDES
249Impaired gastric emptyingOFFSIDES
250Impaired self-careOFFSIDES
251Inappropriate affectOFFSIDES
252IncoherentOFFSIDES
253IncontinenceOFFSIDES
254InfectionOFFSIDES
255Injection site cellulitisOFFSIDES
256Insulin-requiring type 2 diabetes mellitusOFFSIDES
257Intention tremorOFFSIDES
258Intentional self-injuryOFFSIDES
259Intermittent ClaudicationOFFSIDES
260Intermittent Explosive DisorderOFFSIDES
261Intestinal PerforationOFFSIDES
262Intracranial AneurysmOFFSIDES
263Joint Range of Motion DecreasedOFFSIDES
264Keratitis siccaOFFSIDES
265Kidney FailureOFFSIDES
266LacerationOFFSIDES
267Lack of spontaneous speechOFFSIDES
268Laryngeal Diseases7270747CTD
269Left Ventricular HypertrophyOFFSIDES
270LethargyOFFSIDES
271Leukopenia neonatalOFFSIDES
272Limb discomfortOFFSIDES
273Limb injuryOFFSIDES
274LipaseOFFSIDES
275Lipids abnormalOFFSIDES
276Long QT SyndromeOFFSIDES
277Loose toothOFFSIDES
278Lysosomal Storage Diseases28551711CTD
279Markedly reduced dietary intakeOFFSIDES
280Memory Disorders4405503CTD
281Mental impairmentOFFSIDES
282Metastatic NeoplasmOFFSIDES
283Motor retardationOFFSIDES
284Movement Disorders33969
974497
1125709
CTD
285Multi-organ disorderOFFSIDES
286Multiple drug overdoseOFFSIDES
287Multiple drug overdose intentionalOFFSIDES
288Muscle Rigidity3089336
9226090
CTD
289Muscle Weakness7465751CTD
290Muscle strainOFFSIDES
291Muscle tightnessOFFSIDES
292Musculoskeletal PainOFFSIDES
293Musculoskeletal chest painOFFSIDES
294Musculoskeletal stiffnessOFFSIDES
295MutismOFFSIDES
296Mydriasis18090571CTD
SIDER
297Myoglobin blood increasedOFFSIDES
298Nausea10917413CTD
SIDER
299NegativismOFFSIDES
300Nephrogenic Diabetes InsipidusOFFSIDES
301NephrolithiasisOFFSIDES
302Nervous tensionOFFSIDES
303NervousnessSIDER
304Neuroleptic Malignant Syndrome1590507
4707025
16669738
CTD
OFFSIDES
305Neurological examination abnormalOFFSIDES
306NeuromaOFFSIDES
307Neutrophil count decreasedOFFSIDES
308Nicotine DependenceOFFSIDES
309Nutritional condition abnormalOFFSIDES
310Ocular Motility Disorders17514191CTD
311Oculogyric crisisOFFSIDES
312Olfactory Nerve DisorderOFFSIDES
313OpisthotonusOFFSIDES
314Oropharyngeal painOFFSIDES
315Orthosis userOFFSIDES
316OsteopetrosisOFFSIDES
317OsteoporosisOFFSIDES
318OsteosclerosisOFFSIDES
319OverdoseOFFSIDES
320OverweightOFFSIDES
321PCO2 decreasedOFFSIDES
322PainOFFSIDES
323PancreatitisOFFSIDES
324Panic disorder with agoraphobiaOFFSIDES
325Parkinson Disease9877318CTD
326Parkinsonian Disorders33969
4405503
9686775
CTD
327Parkinsonian rest tremorOFFSIDES
328PeriarthritisOFFSIDES
329PericarditisOFFSIDES
330Periodontal operationOFFSIDES
331Periumbilical abscessOFFSIDES
332Perivascular dermatitisOFFSIDES
333Pharyngeal Diseases7270747
11569473
CTD
334Physical assaultOFFSIDES
335Physical disabilityOFFSIDES
336Pleural decorticationOFFSIDES
337PoikilocytosisOFFSIDES
338PolychondritisOFFSIDES
339Polysubstance dependenceOFFSIDES
340PolyuriaOFFSIDES
341Poor dental conditionOFFSIDES
342Poor personal hygieneOFFSIDES
343Portal HypertensionOFFSIDES
344Post procedural infectionOFFSIDES
345PresbyopiaOFFSIDES
346Prescribed overdoseOFFSIDES
347Pressure of speechOFFSIDES
348PriapismOFFSIDES
349Product substitution issueCanada Vigilance: 1Canada Vigilance
350Productive CoughOFFSIDES
351Psychiatric symptomOFFSIDES
352Psychomotor Agitation453364
464141
4405503
CTD
353Psychoses, Substance-Induced4163280
7202232
CTD
354Psychotic Disorders6627044CTD
355Pulmonary HypertensionOFFSIDES
356Pulmonary congestionOFFSIDES
357PurulenceOFFSIDES
358Purulent dischargeOFFSIDES
359Pyoderma GangrenosumOFFSIDES
360Rectal ProlapseOFFSIDES
361Respiratory TherapyOFFSIDES
362Respiratory tract congestionOFFSIDES
363RetrocollisOFFSIDES
364Retrograde amnesiaOFFSIDES
365RhabdomyolysisOFFSIDES
366Risus sardonicusOFFSIDES
367Schizoaffective DisorderOFFSIDES
368Schizophrenia1119614CTD
OFFSIDES
369Schizotypal Personality DisorderOFFSIDES
370Seizures9877318CTD
371Senile dementiaOFFSIDES
372Sialorrhea3978350CTD
373Similar reaction on previous exposure to drugOFFSIDES
374SinobronchitisOFFSIDES
375Sinus bradycardiaOFFSIDES
376SinusitisOFFSIDES
377Skeletal injuryOFFSIDES
378Sleep TalkingOFFSIDES
379SmokerOFFSIDES
380SnoringOFFSIDES
381SoliloquyOFFSIDES
382Somnambulism3093469CTD
383SomnolenceCanada Vigilance: 1Canada Vigilance
384Splenic cystOFFSIDES
385Sputum culture positiveOFFSIDES
386StaringOFFSIDES
387StarvationOFFSIDES
388Stem cell transplantOFFSIDES
389StressOFFSIDES
390Subcutaneous AbscessOFFSIDES
391Substance Withdrawal Syndrome2889760
6362765
CTD
392Sudden Cardiac DeathOFFSIDES
393Sudden deathOFFSIDES
394Superior Mesenteric Artery Syndrome2486013CTD
395Supraventricular tachycardiaOFFSIDES
396TachycardiaSIDER
397TachyphreniaOFFSIDES
398Tardive DyskinesiaOFFSIDES
399Temperature regulation disorderOFFSIDES
400Temporal ArteritisOFFSIDES
401TendinitisOFFSIDES
402TenosynovitisOFFSIDES
403TensionSIDER
404Therapy non-responderOFFSIDES
405ThoracotomyOFFSIDES
406Thromboembolic strokeOFFSIDES
407ThrombophlebitisOFFSIDES
408Tobacco userOFFSIDES
409Tooth ExtractionOFFSIDES
410Tooth InfectionOFFSIDES
411Torsades de Pointes2416504CTD
412Torticollis5574054
7299979
15349021
CTD
413Tremor1260604
9877318
CTD
414TrichiasisOFFSIDES
415Trismus5574054CTD
416Troponin I increasedOFFSIDES
417Unresponsive to stimuliOFFSIDES
418Unresponsive to verbal stimuliOFFSIDES
419Vasculitic rashOFFSIDES
420Vena cava filter insertionOFFSIDES
421VerbigerationOFFSIDES
422Visceral congestionOFFSIDES
423Vital functions abnormalOFFSIDES
424VomitingSIDER
425Vulvovaginal burning sensationOFFSIDES
426Weight Gain10917413CTD
OFFSIDES
427Wheelchair userOFFSIDES
428Wound InfectionOFFSIDES
429Wound dehiscenceOFFSIDES
430Xerostomia2056136
10770471
CTD
431furuncleOFFSIDES
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