Trimipramine
(ZSCDBOWYZJWBIY-UHFFFAOYSA-N)
Structure
- SMILES
- CN(CC(CN1c2ccccc2CCc2c1cccc2)C)C
- Type(s)
- Approved
- ATC code(s)
- N06AA06
- Molecular Formula:
- C20H26N2
- Molecular Weight:
- 294.434
- Log P:
- 4.1860
- Hydrogen Bond Acceptor:
- 1
- Hydrogen Bond Donor:
- 0
- TPSA:
- 6.48
- CAS Number(s):
- 739-71-9; 3564-66-7; 3564-75-8
Synonym(s)
1.
Trimipramine
2.
Trimeprimine
3.
10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine
4.
Apo-Trimip
5.
Eldoral
6.
Herphonal
7.
Novo-Tripramine
8.
Nu-Trimipramine
9.
Rhotrimine
10.
Stangyl
11.
Surmontil
12.
Surmontil Maleate
13.
Trimidura
14.
Trimineurin
15.
Trimineurin Maleate
16.
Trimipramin AZU
17.
Trimipramin Beta
18.
Trimipramin Stada
19.
Trimipramin-Neurazpharm
20.
Trimipramine Maleate
21.
Trimipramine Maleate (1:1)
22.
Trimipramine Maleate (1:1), (+)-Isomer
23.
Trimipramine Maleate (1:1), (+-)-Isomer
24.
Trimipramine Maleate (1:1), (-)-Isomer
25.
Trimipramine Mesylate
26.
Trimipramine Monohydrochloride
27.
Trimipramine, (+-)-Isomer
28.
Trimipramine, (-)-Isomer
29.
Apo Trimip
30.
ApoTrimip
31.
Beta, Trimipramin
32.
Novo Tripramine
33.
NovoTripramine
34.
Nu Trimipramine
35.
NuTrimipramine
36.
Trimipramin Neurazpharm
37.
TrimipraminNeurazpharm
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Anxiety | FAERS: 2 Canada Vigilance: 10 | Canada Vigilance OFFSIDES SIDER US FAERS | |
| 2 | Disorientation | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 3 | Drug ineffective | FAERS: 2 | US FAERS | |
| 4 | Adverse event | FAERS: 1 | US FAERS | |
| 5 | Aphasia | FAERS: 1 | US FAERS | |
| 6 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 7 | Chills | FAERS: 1 | US FAERS | |
| 8 | Delirium | FAERS: 1 | US FAERS | |
| 9 | Dizziness | FAERS: 1 Canada Vigilance: 11 | Canada Vigilance SIDER US FAERS | |
| 10 | Dyscalculia | FAERS: 1 | US FAERS | |
| 11 | Feeling abnormal | FAERS: 1 | SIDER US FAERS | |
| 12 | Hypersomnia | FAERS: 1 | US FAERS | |
| 13 | Hypophagia | FAERS: 1 | US FAERS | |
| 14 | Illogical thinking | FAERS: 1 | US FAERS | |
| 15 | Incoherent | FAERS: 1 | US FAERS | |
| 16 | Loose associations | FAERS: 1 | US FAERS | |
| 17 | Product quality issue | FAERS: 1 | US FAERS | |
| 18 | Product substitution issue | FAERS: 1 | US FAERS | |
| 19 | Stress | FAERS: 1 | US FAERS | |
| 20 | Syncope | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 21 | Tremor | FAERS: 1 Canada Vigilance: 10 | Canada Vigilance SIDER US FAERS | |
| 22 | Abdominal Cramps | SIDER | ||
| 23 | Abdominal Pain | SIDER | ||
| 24 | Abdominal discomfort | OFFSIDES | ||
| 25 | Acidosis | OFFSIDES | ||
| 26 | Actinomycosis | OFFSIDES | ||
| 27 | Acute Coronary Syndrome | SIDER | ||
| 28 | Acute kidney injury | 3458072 | CTD | |
| 29 | Acute myocardial infarction | OFFSIDES | ||
| 30 | Adenitis | SIDER | ||
| 31 | Agitation | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 32 | Agranulocytosis | SIDER | ||
| 33 | Akathisia | Canada Vigilance: 4 | Canada Vigilance | |
| 34 | Alanine Aminotransferase Increased | OFFSIDES | ||
| 35 | Alcohol consumption | OFFSIDES | ||
| 36 | Alcohol-Related Disorders | 2925603 | CTD | |
| 37 | Alcoholic Intoxication | OFFSIDES | ||
| 38 | Alopecia | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 39 | Alveolitis | OFFSIDES | ||
| 40 | Amnesia | OFFSIDES | ||
| 41 | Amphetamines | OFFSIDES | ||
| 42 | Analgesia | OFFSIDES | ||
| 43 | Angioedema | Canada Vigilance: 1 | Canada Vigilance | |
| 44 | Anorexia | SIDER | ||
| 45 | Antidepressant drug level above therapeutic | OFFSIDES | ||
| 46 | Antipsychotic drug level above therapeutic | OFFSIDES | ||
| 47 | Aortic Aneurysm | OFFSIDES | ||
| 48 | Asthenia | Canada Vigilance: 3 | Canada Vigilance OFFSIDES SIDER | |
| 49 | Ataxia | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 50 | Atrioventricular Block | Canada Vigilance: 1 | Canada Vigilance OFFSIDES SIDER | |
| 51 | Back Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 52 | Benign Neoplasm | OFFSIDES | ||
| 53 | Bipolar Disorder | 2340328 3559536 | CTD | |
| 54 | Black hairy tongue | SIDER | ||
| 55 | Blepharospasm | OFFSIDES | ||
| 56 | Blood alkaline phosphatase increased | OFFSIDES | ||
| 57 | Blood creatine phosphokinase MB increased | OFFSIDES | ||
| 58 | Blood creatine phosphokinase increased | OFFSIDES | ||
| 59 | Blood creatinine increased | OFFSIDES | ||
| 60 | Blood potassium decreased | OFFSIDES | ||
| 61 | Blood potassium increased | OFFSIDES | ||
| 62 | Blood prolactin increased | OFFSIDES | ||
| 63 | Blood sodium | OFFSIDES | ||
| 64 | Blood triglycerides increased | OFFSIDES | ||
| 65 | Bone marrow depression | SIDER | ||
| 66 | Bradycardia | OFFSIDES | ||
| 67 | Brain Abscess | OFFSIDES | ||
| 68 | Bulimia | OFFSIDES | ||
| 69 | Capillary Leak Syndrome | OFFSIDES | ||
| 70 | Cardiac stress test abnormal | OFFSIDES | ||
| 71 | Cataplexy | OFFSIDES | ||
| 72 | Cerebrovascular accident | SIDER | ||
| 73 | Chemotherapeutic drug level increased | OFFSIDES | ||
| 74 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 75 | Choking | OFFSIDES | ||
| 76 | Chromaturia | OFFSIDES | ||
| 77 | Circumstance or information capable of leading to medication error | OFFSIDES | ||
| 78 | Cirrhosis | OFFSIDES | ||
| 79 | Clostridium colitis | OFFSIDES | ||
| 80 | Completed Suicide | Canada Vigilance: 8 | Canada Vigilance | |
| 81 | Confabulation | OFFSIDES | ||
| 82 | Conjunctival deposit | OFFSIDES | ||
| 83 | Constipation | Canada Vigilance: 3 | Canada Vigilance SIDER | |
| 84 | Depressed Level of Consciousness | OFFSIDES | ||
| 85 | Depressive disorder | 2857709 6425500 11929455 | CTD | |
| 86 | Dermatitis | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 87 | Diplopia | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Discomfort | SIDER | ||
| 89 | Disturbance in sexual arousal | SIDER | ||
| 90 | Drowsiness | OFFSIDES SIDER | ||
| 91 | Drug Tolerance | OFFSIDES | ||
| 92 | Drug level below therapeutic | OFFSIDES | ||
| 93 | Drug level increased | Canada Vigilance: 3 | Canada Vigilance | |
| 94 | Drug screen positive | OFFSIDES | ||
| 95 | Drug toxicity | OFFSIDES | ||
| 96 | Drug withdrawal syndrome | SIDER | ||
| 97 | Dysgeusia | SIDER | ||
| 98 | Dyspepsia | SIDER | ||
| 99 | Dysphonia | OFFSIDES | ||
| 100 | Dysthymic Disorder | OFFSIDES | ||
| 101 | Dystonia | Canada Vigilance: 5 | Canada Vigilance OFFSIDES | |
| 102 | Dysuria | OFFSIDES | ||
| 103 | Eczema | OFFSIDES | ||
| 104 | Electrocardiogram abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 105 | Electrocardiogram repolarisation abnormality | OFFSIDES | ||
| 106 | Electroconvulsive Therapy | OFFSIDES | ||
| 107 | Enterocolitis | OFFSIDES | ||
| 108 | Eosinophilia | SIDER | ||
| 109 | Epidermal necrosis | OFFSIDES | ||
| 110 | Epigastric distress | SIDER | ||
| 111 | Epilepsy | OFFSIDES | ||
| 112 | Erectile dysfunction | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 113 | Erysipelas | OFFSIDES | ||
| 114 | Erythema | Canada Vigilance: 1 | Canada Vigilance | |
| 115 | Excoriation | OFFSIDES | ||
| 116 | Fatigue | Canada Vigilance: 1 | Canada Vigilance OFFSIDES SIDER | |
| 117 | Flat affect | OFFSIDES | ||
| 118 | Flushing | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 119 | Gamma-Glutamyltransferase Increased | OFFSIDES | ||
| 120 | Gaze palsy | OFFSIDES | ||
| 121 | General physical health deterioration | OFFSIDES | ||
| 122 | Headache | Canada Vigilance: 9 | Canada Vigilance SIDER | |
| 123 | Hemiplegia | OFFSIDES | ||
| 124 | Hepatic necrosis | OFFSIDES | ||
| 125 | Hepatitis B positive | OFFSIDES | ||
| 126 | High density lipoprotein increased | OFFSIDES | ||
| 127 | Hyperkinesia | Canada Vigilance: 2 | Canada Vigilance | |
| 128 | Hypomania | OFFSIDES SIDER | ||
| 129 | Hypotension | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 130 | Incontinence | OFFSIDES | ||
| 131 | Intention tremor | OFFSIDES | ||
| 132 | Intentional self-injury | OFFSIDES | ||
| 133 | Intermittent Claudication | OFFSIDES | ||
| 134 | Keratitis sicca | OFFSIDES | ||
| 135 | Lethargy | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 136 | Leukoencephalopathy | OFFSIDES | ||
| 137 | Lividity | OFFSIDES | ||
| 138 | Lymphadenitis | SIDER | ||
| 139 | Malaise | SIDER | ||
| 140 | Malaria | 23129054 | CTD | |
| 141 | Mental Retardation | OFFSIDES | ||
| 142 | Mental disorder due to a general medical condition | OFFSIDES | ||
| 143 | Mental disorders | 16856516 | CTD | |
| 144 | Mental impairment | OFFSIDES | ||
| 145 | Multiple drug overdose | OFFSIDES | ||
| 146 | Multiple drug overdose intentional | OFFSIDES | ||
| 147 | Multiple sclerosis relapse | OFFSIDES | ||
| 148 | Muscle necrosis | OFFSIDES | ||
| 149 | Musculoskeletal stiffness | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 150 | Mydriasis | SIDER | ||
| 151 | Myocardial Infarction | SIDER | ||
| 152 | Nail bed tenderness | OFFSIDES | ||
| 153 | Nasopharyngitis | OFFSIDES | ||
| 154 | Nausea | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 155 | Negativism | OFFSIDES | ||
| 156 | Neonatal cardiac failure | OFFSIDES | ||
| 157 | Neonatal hypotension | OFFSIDES | ||
| 158 | Neuroleptic Malignant Syndrome | 2925603 | CTD | |
| 159 | Numbness | SIDER | ||
| 160 | Oculogyric crisis | OFFSIDES | ||
| 161 | Onychalgia | OFFSIDES | ||
| 162 | Oropharyngeal discomfort | SIDER | ||
| 163 | Oropharyngeal pain | SIDER | ||
| 164 | Pallor | OFFSIDES | ||
| 165 | Palpitations | SIDER | ||
| 166 | Pancytopenia | SIDER | ||
| 167 | Paresthesia of limbs | SIDER | ||
| 168 | Parotid swelling | SIDER | ||
| 169 | Petechiae | SIDER | ||
| 170 | Pneumoconiosis | OFFSIDES | ||
| 171 | Polysubstance abuse | OFFSIDES | ||
| 172 | Portal Hypertension | OFFSIDES | ||
| 173 | Post procedural pain | OFFSIDES | ||
| 174 | Pruritus | Canada Vigilance: 3 | Canada Vigilance SIDER | |
| 175 | Pulmonary necrosis | OFFSIDES | ||
| 176 | Purpura | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 177 | Rash erythematous | Canada Vigilance: 3 | Canada Vigilance | |
| 178 | Renal failure neonatal | OFFSIDES | ||
| 179 | Restlessness | Canada Vigilance: 3 | Canada Vigilance | |
| 180 | Seizures | 11144696 | CTD | |
| 181 | Sinus Tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 182 | Skin laceration | OFFSIDES | ||
| 183 | Sleep study abnormal | OFFSIDES | ||
| 184 | Somatoform Disorder | OFFSIDES | ||
| 185 | Somnolence | Canada Vigilance: 26 | Canada Vigilance SIDER | |
| 186 | Sopor | OFFSIDES | ||
| 187 | Status Epilepticus | OFFSIDES | ||
| 188 | Stomatitis | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 189 | Sudden onset of sleep | OFFSIDES | ||
| 190 | Sunburn | Canada Vigilance: 1 | Canada Vigilance | |
| 191 | Tachycardia | SIDER | ||
| 192 | Taste peculiar | SIDER | ||
| 193 | Thrombocytopenia | SIDER | ||
| 194 | Tinnitus | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 195 | Unevaluable event | OFFSIDES | ||
| 196 | Urinary Retention | Canada Vigilance: 3 | Canada Vigilance SIDER | |
| 197 | Urticaria | SIDER | ||
| 198 | Vascular purpura | SIDER | ||
| 199 | Ventricular Fibrillation | OFFSIDES | ||
| 200 | Visual disturbance | OFFSIDES | ||
| 201 | Vomiting | Canada Vigilance: 3 | Canada Vigilance SIDER | |
| 202 | Weight decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 203 | jaundice | Canada Vigilance: 1 | Canada Vigilance SIDER |
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